CDK9 (NM_001261) Human Untagged Clone
CAT#: SC119344
CDK9 (untagged)-Human cyclin-dependent kinase 9 (CDK9)
CNY 3,656.00
Cited in 3 publications. |
Product images
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | C-2k; CDC2L4; CTK1; PITALRE; TAK |
Vector | pCMV6-XL5 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene ORF sequence for NM_001261 edited
ATGGCAAAGCAGTACGACTCGGTGGAGTGCCCTTTTTGTGATGAAGTTTCCAAATACGAG AAGCTCGCCAAGATCGGCCAAGGCACCTTCGGGGAGGTGTTCAAGGCCAGGCACCGCAAG ACCGGCCAGAAGGTGGCTCTGAAGAAGGTGCTGATGGAAAACGAGAAGGAGGGGTTCCCC ATTACAGCCTTGCGGGAGATCAAGATCCTTCAGCTTCTAAAACACGAGAATGTGGTCAAC TTGATTGAGATTTGTCGAACCAAAGCTTCCCCCTATAACCGCTGCAAGGGTAGTATATAC CTGGTGTTCGACTTCTGCGAGCATGACCTTGCTGGGCTGTTGAGCAATGTTTTGGTCAAG TTCACGCTGTCTGAGATCAAGAGGGTGATGCAGATGCTGCTTAACGGCCTCTACTACATC CACAGAAACAAGATCCTGCATAGGGACATGAAGGCTGCTAATGTGCTTATCACTCGTGAT GGGGTCCTGAAGCTGGCAGACTTTGGGCTGGCCCGGGCCTTCAGCCTGGCCAAGAACAGC CAGCCCAACCGCTACACCAACCGTGTGGTGACACTCTGGTACCGGCCCCCGGAGCTGTTG CTCGGGGAGCGGGACTACGGCCCCCCCATTGACCTGTGGGGTGCTGGGTGCATCATGGCA GAGATGTGGACCCGCAGCCCCATCATGCAGGGCAACACGGAGCAGCACCAACTCGCCCTC ATCAGTCAGCTCTGCGGCTCCATCACCCCTGAGGTGTGGCCAAACGTGGACAACTATGAG CTGTACGAAAAGCTGGAGCTGGTCAAGGGCCAGAAGCGGAAGGTGAAGGACAGGCTGAAG GCCTATGTGCGTGACCCATACGCACTGGACCTCATCGACAAGCTGCTGGTGCTGGACCCT GCCCAGCGCATCGACAGCGATGACGCCCTCAACCACGACTTCTTCTGGTCCGACCCCATG CCCTCCGACCTCAAGGGCATGCTCTCCACCCACCTGACGTCCATGTTCGAGTACTTGGCA CCACCGCGCCGGAAGGGCAGCCAGATCACCCAGCAGTCCACCAACCAGAGTCGCAATCCC GCCACCACCAACCAGACGGAGTTTGAGCGCGTCTTCTGA >OriGene 5' read for NM_001261 unedited
TGTAATACGACTCACTATAGGGCGGCCGCNGAATCGGCACGAGGCTCCGGCGCCCCGGCT CCCCGCGCCCCCGATCGGGGCCGCCGCTAGTAGTGGCGGCGGCGGAGGCGGGGGCAGCGG CGGCGGCGGCGGAGGCGCCTCTGCAGCTCCGGCTCCCCCTGGCCTCTCGGGAACTACAAG TCCCAGGGGGCCTGGCGGTGGGCGGCGGGCGGAAGAGGCGGGGTCGGCGCCGCGAGGCCG GAAGTGGCCGTGGAGGCGGAAGTGGCGCGGCCGCGGAGGGGCCTGGAGTGCGGCGGCGGC GGGACCCGGAGCAGGAGCGGCGGCAGCAGCGACTGGGGGCGGCGGCGGCGCGTTGGAGGC GGCCATGGCAAAGCAGTACGACTCGGTGGAGTGCCCTTTTTGTGATGAAGTTTCCAAATA CGAGAAGCTCGCCAAGATCGGCCAAGGCACCTTCGGGGAGGTGTTCAAGGCCAGGCACCG CAAGACCGGCCAGAAGGTGGCTCTGAAGAAGGTGCTGATGGAAAACGAGAAGGAGGGGTT CCCCATTACAGCCTTGCGGGAGATCAAGATCCTTCAGCTTCTAAAACACGAGAATGTGGT CAACTTGATTGAGATTTGTCGAACCAAAGCTTCCCCCTATAACCGCTGCAAGGGTAGTAT ATACCCTGGTGTTCGACTTCTGCGAGCATGACCTTGCTGGGCTGTTGAGCAATGTTNTGG TCAAGTTCACGCTGTCTGAGATCAAGAAGGTGATGCAGATGCTGCTTAACGGCCTCTACT ACATCCACAGAAACAAGATCCTGCATAGGGACATGAAGGCTGCTAATGTGCTTACACTCG TGGATGGGGTCCTGAGCTGGCGACTTTGGGCTGGCCCGGNCCTTCACCTGGCAAGAACAG CAGCCCACCGTACACACCGGTGTGTGACCTCTG >OriGene 3' read for NM_001261 unedited
TACTTGGGGAAAAAATTTACAAAAATAAAATTNCAACTTTTTTAATTCTAACGGAACCAA ACTGTGCCCAGGAATGTCTCCAAACAATGGAACCAAAAGAAACACAGTAAAATTCTCCTG TTGAAGAAACCAAGAGTTTGTGCCAGCCCCAGTGTTTCTGAGGGTTAGGCCAAAAACAGC CCATTCCTGAGGCGAGCCCTGTCCCCACGCAGGGTTCTCAGCCCGAGAATAGGATTGTGG GTGGGTGAGGGACCTGTCCCCTCTTCCACCACGCCGGGAGCTCTTAGAAAAAGTCACTGG TGGGCGAGCCCATCCTCCTACCCCATGGAAACCCTCTGGGAACCATCCAGAAAACCAGCA AGGACAAGACAGCTCCAGTGCCCTCCTGGTCTCTCAGCCAATGCTCCACTCCAGTCCACT CAGCGGGCTGCTCCCAGAGCCCAGGGTGGGGATTAAATAAAATATGCATGAGAGATATAA ACTCAAATGCCCTGTCTCCACGATGCAAGTCACATAGCAGAAGAAAAAAAACACAAGAGC CCTAGTGGCAAGCGCCGGCCCTCAGAAGACGCGCTCAAACTCCGTCTGGTTGGTGGTGGC GGGATTGCGACTCTGGTTGGTGGACTGCTGGGTGATCTGGCTGCCCTTCCGGCGCGGTGG TGCCAAGTACTCCAACATGGACGTCAGGTGGGGTGGAGAGCATGCCCTTTGAGTCCGAGG GCATGGGGTCGGACCAAANAAGTCGTGGTTGAAGGCGTCATCGCTGTCCATGCGCTGGGC CAGGTCCAACACCACCACCTTTGTCATGAGGGCCAATGCCTATGGGTCACGCCATAAGCC CTTAAACTGGCCTTTACCTTCCCCTTTTGGCCCTTGACCAGCTCAGCTTTTTCCTCCGCT CATAAGTGTTCACCTTGGGCCACACCTCCGGGGTGAAGGGAC |
Restriction Sites | NotI-NotI |
ACCN | NM_001261 |
Insert Size | 1910 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_001261.2, NP_001252.1 |
RefSeq Size | 1791 bp |
RefSeq ORF | 1119 bp |
Locus ID | 1025 |
UniProt ID | P50750 |
Domains | pkinase, TyrKc, S_TKc |
Protein Families | Druggable Genome, Protein Kinase, Transcription Factors |
Gene Summary | The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS. [provided by RefSeq, Jul 2008] |
Citations (3)
The use of this cDNA Clones has been cited in the following citations: |
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The Zinc-Finger Antiviral Protein ZAP Inhibits LINE and Alu Retrotransposition
,Moldovan, JB;Moran, JV;,
PLoS Genet.
,PubMed ID 25951186
[CDK9]
|
Acute Targeting of General Transcription Factor IIB Restricts Cardiac Hypertrophy via Selective Inhibition of Gene Transcription
,Sayed, D;Yang, Z;He, M;Pfleger, JM;Abdellatif, M;,
Circ Heart Fail
,PubMed ID 25398966
[CDK9]
|
CDKN1C Negatively Regulates RNA Polymerase II C-terminal Domain Phosphorylation in an E2F1-dependent Manner
,Yihong Ma, Lu Chen, Gabriela M. Wright, Smitha R. Pillai, Srikumar P. Chellappan, and W. Douglas Cress,
J. Biol. Chem., Mar 2010; 285: 9813 - 9822
[CDK9]
|
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Other Versions
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RC201603L3 | Lenti ORF clone of Human cyclin-dependent kinase 9 (CDK9), Myc-DDK-tagged |
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RC201603L4 | Lenti ORF clone of Human cyclin-dependent kinase 9 (CDK9), mGFP tagged |
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