United States
Germany
Japan
United Kingdom
China
DAXX (NM_001350) Human Untagged Clone
CAT＃: SC119273
DAXX (untagged)-Human death-domain associated protein (DAXX), transcript variant 2
CNY 5,432.00
CNY 7,220.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | BING2; DAP6; EAP1; SMIM40 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC119273 sequence for NM_001350 edited (data generated by NextGen Sequencing)
ATGGCCACCGCTAACAGCATCATCGTGCTGGATGATGATGACGAAGATGAAGCAGCTGCT CAGCCAGGGCCCTCCCACCCACTCCCCAATGCGGCCTCACCTGGGGCAGAAGCCCCTAGC TCCTCTGAGCCTCATGGGGCCAGAGGAAGCAGTAGTTCGGGCGGCAAGAAATGCTACAAG CTGGAGAATGAGAAGCTGTTCGAAGAGTTCCTTGAACTTTGTAAGATGCAGACAGCAGAC CACCCTGAGGTGGTCCCATTCCTCTATAACCGGCAGCAACGTGCCCACTCTCTGTTTTTG GCCTCGGCGGAGTTCTGCAACATCCTCTCTAGGGTCCTGTCTCGGGCCCGGAGCCGGCCA GCCAAGCTCTATGTCTACATCAATGAGCTCTGCACTGTTCTCAAGGCCCACTCAGCCAAA AAGAAGCTGAACTTGGCCCCTGCCGCCACCACCTCCAATGAGCCCTCTGGGAATAACCCT CCCACACACCTCTCCTTGGACCCCACAAATGCTGAAAACACTGCCTCTCAGTCTCCAAGG ACCCGTGGTTCCCGGCGGCAGATCCAGCGTTTGGAGCAGCTGCTGGCGCTCTATGTGGCA GAGATCCGGCGGCTGCAGGAAAAGGAGTTGGATCTCTCAGAATTGGATGACCCAGACTCC GCATACCTGCAGGAGGCACGGTTGAAGCGTAAGCTGATCCGCCTCTTTGGGCGACTATGT GAGCTGAAAGACTGCTCTTCACTGACCGGCCGTGTCATAGAGCAGCGCATCCCCTACCGT GGCACCCGCTACCCAGAGGTTAACAGGCGCATTGAGCGGCTCATCAACAAGCCAGGGCCT GATACCTTCCCTGACTATGGGGATGTGCTTCGGGCTGTAGAGAAGGCAGCTGCCCGACAC AGCCTTGGCCTCCCCCGACAGCAGCTCCAGCTCATGGCTCAGGATGCCTTCCGAGATGTG GGCATCAGGTTACAGGAGCGACGTCACCTCGATCTCATCTACAACTTTGGCTGCCACCTC ACAGATGACTATAGGCCAGGCGTTGACCCTGCACTATCAGATCCTGTGTTGGCCCGGCGC CTTCGGGAAAACCGGAGTTTGGCCATGAGTCGGCTGGATGAGGTCATCTCCAAATATGCA ATGTTGCAAGACAAAAGTGAGGAGGGCGAGAGAAAAAAGAGAAGAGCTCGGCTCCAAGGC ACCTCTTCCCACTCTGCAGACACCCCCGAAGCCTCCTTGGATTCTGGTGAGGGCCCTAGT GGAATGGCATCCCAGGGGTGCCCTTCTGCCTCCAGAGCTGAGACAGATGACGAAGACGAT GAGGAGAGTGATGAGGAAGAGGAGGAGGAGGAGGAAGAAGAAGAGGAGGAGGCCACAGAT TCTGAAGAGGAGGAGGATCTGGAACAGATGCAGGAGGGTCAGGAGGATGATGAAGAGGAG GACGAAGAGGAAGAAGCAGCAGCAGGTAAAGATGGAGACAAGAGCCCCATGTCCTCACTA CAGATCTCCAATGAAAAGAACCTGGAACCTGGCAAACAGATCAGCAGATCTTCAGGGGAG CAGCAAAACAAAGGACGCATAGTGTCACCATCGTTACTGTCAGAAGAACCCCTGGCCCCC TCCAGCATAGATGCTGAAAGCAATGGAGAACAGCCTGAGGAGCTGACCCTGGAGGAAGAA AGCCCTGTGTCTCAGCTCTTTGAGCTAGAGATTGAAGCTTTGCCCCTGGATACCCCTTCC TCTGTGGAGACGGACATTTCCTCTTCCAGGAAGCAATCAGAGGAGCCCTTCACCACTGTC TTAGAGAATGGAGCAGGCATGGTCTCTTCTACTTCCTTCAATGGAGGCGTCTCTCCTCAC AACTGGGGAGATTCTGGTCCCCCCTGCAAAAAATCTCGGAAGGAGAAGAAGCAAACAGGA TCAGGGCCATTAGGAAACAGCTATGTGGAAAGGCAAAGGTCAGTGCATGAGAAGAATGGG AAAAAGATATGTACCCTGCCCAGCCCACCTTCCCCCTTGGCTTCCTTGGCCCCAGTTGCT GATTCCTCCACGAGGGTGGACTCTCCCAGCCATGGCCTGGTGACCAGCTCCCTCTGCATC CCTTCTCCAGCCCGGCTGTCCCAAACCCCCCATTCACAGCCTCCTCGGCCTGGTACTTGC AAGACAAGTGTGGCCACACAATGCGATCCAGAAGAGATCATCGTGCTCTCAGACTCTGAT TAG Clone variation with respect to NM_001350.4 >OriGene 5' read for NM_001350 unedited
GGTTTANAATAGTATACGACTCCTATAGGGCGGCCGCGAATTCGCACGAGGGTGGGAGTG GGAAGGAAGGCGGAGGGAACCATGCGAGGTTCTGAGAATTGCGGCGAGGGTCGCCTCGAG AGACGGTTTCTGAGCAGGAATTCTGAAATCCCCACCACTTCCTCCCTCCGGGGGATTTGA TCCCCTATGGCCACCGCTAACAGCATCATCGTGCTGGATGATGATGACGAAGATGAAGCA GCTGCTCAGCCAGGGCCCTCCCACCCACTCCCCAATGCGGCCTCACCTGGGGCAGAAGCC CCTAGCTCCTCTGAGCCTCATGGGGCCAGAGGAAGCAGTAGTTCGGGCGGCAAGAAATGC TACAAGCTGGAGAATGAGAAGCTGTTCGAAGAGTTCCTTGAACTTTGTAAGATGCAGACA GCAGACCACCCTGAGGTGGTCCCATTCCTCTATAACCGGCAGCAACGTGCCCACTCTCTG TTTTTGGCCTCGGCGGAGTTCTGCAACATCCTCTCTAGGGTCCTGTCTCGGGCCCGGAGC CGGCCAGCCAAGCTCTATGTCTACATCAATGAGCTCTGCACTGTTCTCAAGGCCCACTCA GCCAAAAAGAAGCTGAACTTGGCCCCTGCCGCCACCACCTCCAATGAGCCCTCTGGGAAT AACCCTCCCACACACCTCTCCTTGGACCCCACAAATGCTGAAAACACTGCCTCTCAGTCT CCAAGGACCCGTGGTTCCCGGCGGCAGATTCAGCGTTTGGAGCAGCTGCTGGCGCTCTAT GGGGCAGAGATCCGGCGGCTGCAGGACAAGGAGTTGGATCTCTCAAANTTGGATGACCCA GACTCCGCATACCTGCAGGAGGCACGGCTGAAGCGTAAGCTGATCCGGCTCTTGGGCGAC TATGNGAGCTG >OriGene 3' read for NM_001350 unedited
CCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTAAAGAAACACCACCAAAGGGGATT AGCTTAGTCCATCCCTTCCTCAGTCATCTGCTTCCCACCTTCCTCCAAATGTTATCCCAT AACATTCTGGAGGCAGGGAGAAGGGGAGGCAGCTAATCAGAGTCTGAGAGCACGATGATC TCTTCTGGATCGCATTGTGTGGCCACACTTGTCTTGCAAGTACCAGGCCGAGGAGGCTGT GAATGGGGGGTTTGGGACAGCCGGGCTGGAGAAGGGATGCAGAGGGAGCTGGTCACCAGG CCATGGCTGGGAGAGTCCACCCTCGTGGAGGAATCAGCAACTGGGGCCAAGGAAGCCAAG GGGGAAGGTGGGCTGGGCAGGGTACATATCTTTTTCCCATTCTTCTCATGCACTGACCTT TGCCTTTCACATAGCTGTTTCCTAATGGCCCTGATCCTGTTTGCTTCTTCTCCTTCCGAG ATTTTTTGCAGGGGGGACCAGAATCTCCCCAGTTGTGAGGAGAGACGCCTCCCTTGAAGG AAGTAGAAGAGACCATGCCTGCTCCATTCTCTAAGACAGCGGTGAAGGGCTCCTCTGATT GCTTCCTGGAAAGGAATTGTCCGCCTCCACAGAGAAGGGGTATCCAAGGGCAAAGCTTCA ATCTCTAGCTCAAAGAGCCGAGACACAGGCCTTTCCTTCCTACCAGGAANCCTCCTCAAG CCGGTCTCCCATTGCTTTCACCTTCTATGCTGGAGGGGCCCACGGTTTCTCTGACAATAA CCAGGGGGACCTATGCGCCCCTTTGTCTTGCTGTTCCCCCGAAAACCGCTGTCTGTCTGC CCCGTTCACGTCTTTTTTTGGAAATTCGCCTCAGACTGGGGCTCTTCCCCCCTTTTTCCA CCGCCGGTCCTTCCTTTCGTCTCCTTTCTATCTCTTCTATCTCTACTTTGTTCCCAATCC CACTTTAAAACAGGGGCCTCCCTTTTTCTCCC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_001350 |
| Insert Size | 2620 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001350.3, NP_001341.1 |
| RefSeq Size | 2477 bp |
| RefSeq ORF | 2223 bp |
| Locus ID | 1616 |
| UniProt ID | Q9UER7 |
| Domains | Daxx |
| Protein Families | Druggable Genome, Stem cell - Pluripotency, Transcription Factors |
| Protein Pathways | Amyotrophic lateral sclerosis (ALS), MAPK signaling pathway |
| Gene Summary | This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2008] Transcript Variant: This variant (2) uses an alternate splice site in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same isoform (a). |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
DAXX Is a New AIRE-interacting Protein
,Allesandra Meloni, Edoardo Fiorillo, Denise Corda, Federica Incani, Maria Luisa Serra, Antonella Contini, Antonio Cao, and Maria Cristina Rosatelli,
J. Biol. Chem., Apr 2010; 285: 13012 - 13021.
[DAXX]
|
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC219497 | DAXX (Myc-DDK-tagged)-Human death-domain associated protein (DAXX), transcript variant 2 |
CNY 5,424.00 |
|
| RC219497L1 | Lenti ORF clone of Human death-domain associated protein (DAXX), transcript variant 2, Myc-DDK-tagged |
CNY 7,824.00 |
|
| RC219497L2 | Lenti ORF clone of Human death-domain associated protein (DAXX), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RC219497L3 | Lenti ORF clone of Human death-domain associated protein (DAXX), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC219497L4 | Lenti ORF clone of Human death-domain associated protein (DAXX), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RG219497 | DAXX (tGFP-tagged) - Human death-domain associated protein (DAXX), transcript variant 2 |
CNY 7,024.00 |
