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alpha smooth muscle Actin (ACTA2) (NM_001613) Human Untagged Clone
CAT＃: SC119152
ACTA2 (untagged)-Human actin, alpha 2, smooth muscle, aorta (ACTA2), transcript variant 2
CNY 3,656.00
| Cited in 1 publication. |
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热销推荐Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ACTSA |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC119152 sequence for NM_001613 edited (data generated by NextGen Sequencing)
ATGTGTGAAGAAGAGGACAGCACTGCCTTGGTGTGTGACAATGGCTCTGGGCTCTGTAAG GCCGGCTTTGCTGGGGACGATGCTCCCAGGGCTGTTTTCCCATCCATTGTGGGACGTCCC AGACATCAGGGGGTGATGGTGGGAATGGGACAAAAAGACAGCTACGTGGGTGACGAAGCA CAGAGCAAAAGAGGAATCCTGACCCTGAAGTACCCGATAGAACATGGCATCATCACCAAC TGGGACGACATGGAAAAGATCTGGCACCACTCTTTCTACAATGAGCTTCGTGTTGCCCCT GAAGAGCATCCCACCCTGCTCACGGAGGCACCCCTGAACCCCAAGGCCAACCGGGAGAAA ATGACTCAAATTATGTTTGAGACTTTCAATGTCCCAGCCATGTATGTGGCTATCCAGGCG GTGCTGTCTCTCTATGCCTCTGGACGCACAACTGGCATCGTGCTGGACTCTGGAGATGGT GTCACCCACAATGTCCCCATCTATGAGGGCTATGCCTTGCCCCATGCCATCATGCGTCTG GATCTGGCTGGCCGAGATCTCACTGACTACCTCATGAAGATCCTGACTGAGCGTGGCTAT TCCTTCGTTACTACTGCTGAGCGTGAGATTGTCCGGGACATCAAGGAGAAACTGTGTTAT GTAGCTCTGGACTTTGAAAATGAGATGGCCACTGCCGCATCCTCATCCTCCCTTGAGAAG AGTTACGAGTTGCCTGATGGGCAAGTGATCACCATCGGAAATGAACGTTTCCGCTGCCCA GAGACCCTGTTCCAGCCATCCTTCATCGGGATGGAGTCTGCTGGCATCCATGAAACCACC TACAACAGCATCATGAAGTGTGATATTGACATCAGGAAGGACCTCTATGCTAACAATGTC CTATCAGGGGGCACCACTATGTACCCTGGCATTGCCGACCGAATGCAGAAGGAGATCACG GCCCTAGCACCCAGCACCATGAAGATCAAGATCATTGCCCCTCCGGAGCGCAAATACTCT GTCTGGATCGGTGGCTCCATCCTGGCCTCTCTGTCCACCTTCCAGCAGATGTGGATCAGC AAACAGGAATACGATGAAGCCGGGCCTTCCATTGTCCACCGCAAATGCTTCTAA Clone variation with respect to NM_001613.2 >OriGene 5' read for NM_001613 unedited
NGGTCGAATTTGTATACGACTCCTATAGGCGGCCCGCGAATTCGCACGAGGGAGCAGCCC AGCCAAGCACTGTCAGGAATCCTGTGAAGCAGCTCCAGCTATGTGTGAAGAAGAGGACAG CACTGCCTTGGTGTGTGACAATGGCTCTGGGCTCTGTAAGGCCGGCTTTGCTGGGGACGA TGCTCCCAGGGCTGTTTTCCCATCCATTGTGGGACGTCCCAGACATCAGGGGGTGATGGT GGGAATGGGACAAAAAGACAGCTACGTGGGTGACGAAGCACAGAGCAAAAGAGGAATCCT GACCCTGAAGTACCCGATAGAACATGGCATCATCACCAACTGGGACGACATGGAAAAGAT CTGGCACCACTCTTTCTACAATGAGCTTCGTGTTGCCCCTGAAGAGCATCCCACCCTGCT CACGGAGGCACCCCTGAACCCCAAGGCCAACCGGGAGAAAATGACTCAAATTATGTTTGA GACTTTCAATGTCCCAGCCATGTATGTGGCTATCCAGGCGGTGCTGTCTCTCTATGCCTC TGGACGCACAACTGGCATCGTGCTGGACTCTGGAGATGGTGTCACCCACAATGTCCCCAT CTATGAGGGCTATGCCTTGCCCCATGCCATCATGCGTCTGGATCTGGCTGGCCGAGATCT CACTGACTACCTCATGAAGATCCTGACTGAGCGTGGCTATTCCTTCGTTACTACTGCTGA GCGTGAGATTGTCCGGGACATCAAGGAGAAACTGTGNTATGTAGCTCTGGACTNTGAAAA TGAGATGGCCACTGCCGCATCCTCATCCTCCCTTGAGAAGAGTTACGAGTTGCCTGATGG GCAAGTGATCACCATCGAANATGAACGTTTTCGCTGCCCANANACCCCTGTCCAGCCATC CTT >OriGene 3' read for NM_001613 unedited
ACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTGCCAGTAGCCTATTTCA GATTTATTAAAAAACACATAGGTAACGAGTCAGAGCTTTGGCTAGGAATGATTTGGAAAA GAACTGAAGGCATAATTCCACAGGACATTCACAGTTGTGTGCTAGAGACAGAGAGGAGCA GGAAAGTGTTTTAGAAGCATTTGCGGTGGACAATGGAAGGCCCGGCTTCATCGTATTCCT GTTTGCTGATCCACATCTGCTGGAAGGTGGACAGAGAGGCCAGGATGGAGCCACCGATCC AGACAGAGTATTTGCGCTCCGGAGGGGCAATGATCTTGATCTTCATGGTGCTGGGTGCTA GGGCCGTGATCTCCTTCTGCATTCGGTCGGCAATGCCAGGGTACATAGTGGTGCCCCCTG ATAGGACATTGTTAGCATAGAGGTCCTTCCTGATGTCAATATCACACTTCATGATGCTGT TGTAGGTGGTTTCATGGATGCCAGCAGACTCCATCCCGATGAAGGATGGCTGGAACAGGG TCTCTGGGCAGCGGAAACGTTCATTTCCGATGGTGATCACTTGCCCATCAGGCAACTCGT AACTCTTCTCAAGGGAGGATGAGGATGCGGCAGTGGCCATCTCATTTTCAAAGTCCAGAG CTACATAACACAGTTTCTCCTTGATGTCCCGGACAATCTCACGCTCAGCAGTAGTTACGA AGGAATAGCCACGCTCAGTCAGGATCTTCATGANGGTAGTCAGTGAGATCTCGGCCAGCC AGATCCAGACGCCTGATGGCATGGGGCAAAGGCTTACCCTCATAGATGGGGACATTGGGG GGACACCTTTCCAAAGTCACACCGAGCCCGTTGGGCGCTCAAAGCATAAAGAGACACACC CGCTGGAAGCCCCCTACCTGGCTGGGACTTGGAAAGTTCAAACTT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_001613 |
| Insert Size | 1410 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001613.1, NP_001604.1 |
| RefSeq Size | 1330 bp |
| RefSeq ORF | 1134 bp |
| Locus ID | 59 |
| UniProt ID | P62736 |
| Domains | ACTIN |
| Protein Pathways | Vascular smooth muscle contraction |
| Gene Summary | This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, integrity, and intercellular signaling. The encoded protein is a smooth muscle actin that is involved in vascular contractility and blood pressure homeostasis. Mutations in this gene cause a variety of vascular diseases, such as thoracic aortic disease, coronary artery disease, stroke, and Moyamoya disease, as well as multisystemic smooth muscle dysfunction syndrome. [provided by RefSeq, Sep 2017] Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1-3 encode the same protein. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Statins Block Calcific Nodule Formation of Valvular Interstitial Cells by Inhibiting {alpha}-Smooth Muscle Actin Expression
,Julie A. Benton, Hanna B. Kern, Leslie A. Leinwand, Peter D. Mariner, and Kristi S. Anseth,
Arterioscler Thromb Vasc Biol, Nov 2009; 29: 1950 - 1957
[ACTA2]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC210641 | ACTA2 (Myc-DDK-tagged)-Human actin, alpha 2, smooth muscle, aorta (ACTA2), transcript variant 2 |
CNY 3,656.00 |
|
| RC210641L1 | Lenti ORF clone of Human actin, alpha 2, smooth muscle, aorta (ACTA2), transcript variant 2, Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC210641L2 | Lenti ORF clone of Human actin, alpha 2, smooth muscle, aorta (ACTA2), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RC210641L3 | Lenti ORF clone of Human actin, alpha 2, smooth muscle, aorta (ACTA2), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC210641L4 | Lenti ORF clone of Human actin, alpha 2, smooth muscle, aorta (ACTA2), transcript variant 2, mGFP tagged |
CNY 6,056.00 |
|
| RG210641 | ACTA2 (tGFP-tagged) - Human actin, alpha 2, smooth muscle, aorta (ACTA2), transcript variant 2 |
CNY 5,256.00 |
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