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INPP5F (OCRL) (NM_001587) Human Untagged Clone
CAT＃: SC119145
OCRL (untagged)-Human oculocerebrorenal syndrome of Lowe (OCRL), transcript variant b
CNY 6,552.00
CNY 7,220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | Dent-2; DENT2; INPP5F; LOCR; NPHL2; OCRL-1; OCRL1 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_001587 edited
ATGGAGCCGCCGCTCCCGGTCGGAGCCCAGCCGCTTGCCACTGTCGAGGGTATGGAGATG AAGGGTCCTCTCCGGGAGCCCTGCGCCCTGACCCTAGCCCAGAGGAACGGGCAATATGAG TTAATAATCCAGTTGCATGAGAAGGAACAGCATGTTCAAGATATCATTCCTATAAATAGC CACTTCAGATGTGTTCAAGAAGCAGAAGAAACTCTTTTGATTGACATAGCTTCTAACAGT GGCTGCAAAATTCGGGTTCAGGGGGACTGGATCAGAGAGCGCCGCTTTGAAATCCCTGAT GAGGAACACTGTTTGAAGTTCCTCTCAGCTGTCCTTGCTGCTCAGAAAGCTCAGTCACAG CTTCTTGTTCCAGAGCAAAAGGACTCATCTAGCTGGTACCAGAAATTAGACACTAAGGAC AAACCTTCTGTTTTTTCAGGGCTTCTTGGATTTGAAGACAATTTTTCTTCTATGAATTTG GACAAGAAAATAAATTCACAAAATCAGCCTACTGGGATTCATCGGGAACCCCCACCTCCA CCCTTTTCAGTGAATAAAATGCTTCCACGTGAAAAAGAAGCTTCTAACAAGGAGCAGCCC AAAGTGACCAACACCATGCGGAAGCTCTTTGTACCAAATACCCAATCTGGGCAGCGGGAG GGTCTCATCAAACATATCCTGGCAAAGCGAGAGAAAGAATATGTCAACATTCAGACTTTC AGATTTTTTGTTGGAACTTGGAATGTGAATGGCCAGTCTCCAGATAGCGGGTTAGAACCT TGGCTGAACTGTGATCCCAATCCTCCTGATATCTACTGCATTGGATTCCAAGAACTGGAC TTGAGCACAGAAGCCTTCTTCTACTTTGAATCTGTGAAGGAACAAGAATGGTCCATGGCT GTAGAGAGAGGTTTGCATTCCAAAGCCAAGTATAAGAAAGTTCAACTGGTGCGCCTTGTT GGGATGATGCTTCTTATATTTGCCAGAAAGGATCAGTGTCGATACATTCGTGATATTGCT ACAGAAACAGTTGGAACTGGAATCATGGGGAAAATGGGAAACAAAGGTGGGGTAGCTGTG AGATTTGTATTTCACAACACCACCTTTTGCATTGTCAATTCCCATCTGGCTGCACACGTG GAGGACTTTGAGAGAAGGAATCAAGATTATAAGGACATTTGTGCGAGAATGAGTTTTGTG GTCCCAAATCAGACCCTCCCGCAGTTGAACATCATGAAACATGAGGTTGTCATTTGGTTG GGAGATTTGAATTATAGACTTTGCATGCCTGATGCCAATGAGGTGAAAAGTCTTATTAAT AAGAAAGACCTTCAGAGACTCTTGAAATTCGACCAGCTAAATATTCAGCGCACACAGAAA AAAGCTTTTGTTGACTTCAATGAAGGGGAAATCAAGTTCATCCCCACTTATAAGTATGAC TCTAAAACAGACCGGTGGGATTCCAGTGGGAAATGCCGGGTTCCAGCCTGGTGTGACCGA ATTCTTTGGAGAGGAACAAATGTTAATCAGCTTAATTATCGGAGTCACATGGAACTGAAA ACCAGCGACCACAAGCCTGTTAGCGCCCTCTTCCATATTGGGGTGAAGGTTGTGGATGAA CGAAGGTACCGGAAAGTCTTTGAAGATAGTGTACGCATCATGGACAGAATGGAAAATGAC TTCCTTCCTTCCTTAGAACTCAGCAGGAGGGAGTTTGTGTTTGAAAATGTGAAGTTTCGG CAACTACAAAAGGAGAAGTTCCAGATCAGCAACAATGGACAGGTTCCCTGCCATTTTTCT TTCATCCCTAAACTTAATGACAGCCAGTACTGCAAGCCATGGCTTCGGGCTGAACCTTTT GAGGGCTACTTGGAGCCAAATGAGACAGTGGACATTTCTCTTGATGTGTATGTCAGCAAA GACTCTGTAACCATCCTGAACTCGGGAGAAGATAAGATTGAAGATATTCTCGTCCTTCAC CTGGATCGAGGCAAAGATTACTTCTTGACTATCAGTGGAAATTACCTCCCAAGTTGTTTT GGCACATCCTTAGAGGCTCTGTGCCGTATGAAAAGACCAATCCGAGAAGTTCCTGTTACC AAACTCATAGACTTGGAGAAATCCCTTCTGCAAATGGTTCCTTTGGATGAAGGTGCCAGT GAGAGACCCCTTCAGGTTCCCAAGGAGATCTGGCTTCTAGTAGATCACCTATTCAAATAC GCCTGTCACCAGGAGGACCTGTTCCAGACCCCTGGAATGCAGGAAGAGCTCCAGCAGATC ATTGATTGTCTGGATACCAGCATTCCTGAGACAATCCCTGGCAGCAACCACTCTGTGGCT GAAGCACTGCTCATTTTCTTGGAAGCCCTGCCAGAGCCAGTCATCTGTTACGAGCTGTAT CAGCGATGTCTTGACTCTGCTTATGATCCCCGGATCTGCCGACAGGTGATCTCCCAGCTT CCGAGATGCCATAGAAATGTTTTCCGTTACTTGATGGCATTCCTTCGAGAACTCTTAAAA TTCTCTGAATACAATAGCGTCAATGCCAACATGATCGCTACTCTCTTCACTAGTCTTCTC CTGAGGCCTCCACCCAACCTTATGGCAAGACAGACTCCAAGTGACCGCCAGCGTGCTATT CAGTTCCTTCTGGGCTTTCTGCTTGGGAGCGAAGAAGACTAA >OriGene 5' read for NM_001587 unedited
CATTATGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGCGCAGCCGAGGT GGGTGGGTGTGGGGACGCGGGAGCCAGTGTCGTCGGATCGGCCCGCAGTCCGCTGTCCTG CTGAGCCCGGAGGCCGCCTGGATGGAGCCGCCGCTCCCGGTCGGAGCCCAGCCGCTTGCC ACTGTCGAGGGTATGGAGATGAAGGGTCCTCTCCGGGAGCCCTGCGCCCTGACCCTAGCC CAGAGGAACGGGCAATATGAGTTAATAATCCAGTTGCATGAGAAGGAACAGCATGTTCAA GATATCATTCCTATAAATAGCCACTTCAGATGTGTTCAAGAAGCAGAAGAAACTCTTTTG ATTGACATAGCTTCTAACAGTGGCTGCAAAATTCGGGTTCAGGGGGACTGGATCAGAGAG CGCCGCTTTGAAATCCCTGATGAGGAACACTGTTTGAAGTTCCTCTCAGCTGTCCTTGCT GCTCAGAAAGCTCAGTCACAGCTTCTTGTTCCAGAGCAAAAGGACTCATCTAGCTGGTAC CAGAAATTAGACACTAAGGACAAACCTTCTGTTTTTTCAGGGCTTCTTGGATTTGAAGAC AATTTTTCTTCTATGAATTTGGACAAGAAAATAAATTCACAAAATCAGCCTACTGGGATT CATCGGGAACCCCCACCTCCACCCTTTTCAGTGAATAAAATGCTTCCACGTGAAAAAGAA GCTTCTAACAAGGAGCAGCCCAAAGTGACCAACACCATGCGGAAGCTCTTTGTACCAAAT ACCCAATCTGGGCAGCGGGAGGGTCTCATCAAACATATCCTGGCANAGCGAGAGAAAGAA TATGTCAACATTCAGAACTTCAGATTTTNTGTTGGAACTTGGNATGTGAATGCCCAGTCT CCAGATAGCGGGNTAGAACCTTGCNCTGACTGTGATCCCCATCCTNCTGATATCTACTGC ATNGGATTCCAGAACTGGNACTGAGCACAAAGN >OriGene 3' read for NM_001587 unedited
TTCNTTGNACCGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTTTTTAACAC AACATATATTTATTCAGAAAAAATTTGCAATAAATTATAATAAAAAAGAGACACGAAATA TAGAATCCCACTAGCAGCTTTGCTTAGTGATCAAGACGTTTTTGGGAAATATAACAAACA ATTACAGAATAAGAAAACAGTGAAAGGGAGACTAATGCAATGTCACCACATGGATTTGAA CCATTTCTTCCCTAAGACAGCAGGTGCAGAGTCTTTCCCTACCAGCTGAATCCGAAATCC TTACTTCAGAGCAGCTACAAATTAGTACCTTAAAGGACTTGGCAATTACAGGTTGGGGTG CTGGAATAGCCATGGTAGGGAAGCAGATTTCTTCTGTCTGGGTCTACATCTTGTCTCCTC TACCTAGAGATTGTCTAAAACTCTCAACTCTGTATATGTTCCAGGATGAGCTGAAAAAAG GTCGAGGCAGTACACCAACTTAGTGTTTTGATCTGATGTACAAAGAGATAGGATACTGCA TACGTGCAGCACAGAGCCTCCACTAACCACACCCTTGATCACCCAAAGATCCCAGGTCAG CGATATGCTAGAAAACAAGCCCAGGAAAGGTATTTTCCTGTGGAATGACCCTACCCAGTG CCTATCATCTGCCTCTTTTTGAGATCACTTTTTGGCCCTGCGGAGATGAACAACTGCTCT TGCCTAAGTCTTCCATTAACTAAGTCCAACACTACCCCCCGACTTATATACCTGCAAATC TGGGCCCACTCCTGGACTTTAAGCTTTACTTCTAAGAGCACGGGTGATCCCTCTGCCACA TACCCCCTTGCCCCCCCCTCCCGATCACATTGACTTCCCTGGTGCCCCTCCCCTCCTCAA TGCCCACACGGTCCCCCGATTACTTACGTCCC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_001587 |
| Insert Size | 5120 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001587.3, NP_001578.2 |
| RefSeq Size | 5141 bp |
| RefSeq ORF | 2682 bp |
| Locus ID | 4952 |
| UniProt ID | Q01968 |
| Domains | RhoGAP, IPPc, Exo_endo_phos |
| Protein Families | Druggable Genome |
| Protein Pathways | Inositol phosphate metabolism, Metabolic pathways, Phosphatidylinositol signaling system |
| Gene Summary | This gene encodes an inositol polyphosphate 5-phosphatase. This protein is involved in regulating membrane trafficking and is located in numerous subcellular locations including the trans-Golgi network, clathrin-coated vesicles and, endosomes and the plasma membrane. This protein may also play a role in primary cilium formation. Mutations in this gene cause oculocerebrorenal syndrome of Lowe and also Dent disease. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016] Transcript Variant: This variant (b) lacks an alternate in-frame exon, compared to variant 1, resulting in a shorter protein (isoform b) that has a shorter C-terminus, compared to isoform 1. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC210491 | OCRL (Myc-DDK-tagged)-Human oculocerebrorenal syndrome of Lowe (OCRL), transcript variant b |
CNY 6,544.00 |
|
| RC210491L3 | Lenti-ORF clone of OCRL (Myc-DDK-tagged)-Human oculocerebrorenal syndrome of Lowe (OCRL), transcript variant b |
CNY 5,890.00 |
|
| RC210491L4 | Lenti-ORF clone of OCRL (mGFP-tagged)-Human oculocerebrorenal syndrome of Lowe (OCRL), transcript variant b |
CNY 5,890.00 |
|
| RG210491 | OCRL (tGFP-tagged) - Human oculocerebrorenal syndrome of Lowe (OCRL), transcript variant b |
CNY 8,144.00 |
