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C5R1 (C5AR1) (NM_001736) Human Untagged Clone
CAT＃: SC119072
C5AR1 (untagged)-Human complement component 5a receptor 1 (C5AR1)
CNY 3,656.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | C5A; C5AR; C5R1; CD88 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC119072 sequence for NM_001736 edited (data generated by NextGen Sequencing)
ATGAACTCCTTCAATTATACCACCCCTGATTATGGGCACTATGATGACAAGGATACCCTG GACCTCAACACCCCTGTGGATAAAACTTCTAACACGCTGCGTGTTCCAGACATCCTGGCC TTGGTCATCTTTGCAGTCGTCTTCCTGGTGGGAGTGCTGGGCAATGCCCTGGTGGTCTGG GTGACGGCATTCGAGGCCAAGCGGACCATCAATGCCATCTGGTTCCTCAACTTGGCGGTA GCCGACTTCCTCTCCTGCCTGGCGCTGCCCATCTTGTTCACGTCCATTGTACAGCATCAC CACTGGCCCTTTGGCGGGGCCGCCTGCAGCATCCTGCCCTCCCTCATCCTGCTCAACATG TACGCCAGCATCCTGCTCCTGGCCACCATCAGCGCCGACCGCTTTCTGCTGGTGTTTAAA CCCATCTGGTGCCAGAACTTCCGAGGGGCCGGCTTGGCCTGGATCGCCTGTGCCGTGGCT TGGGGTTTAGCCCTGCTGCTGACCATACCCTCCTTCCTGTACCGGGTGGTCCGGGAGGAG TACTTTCCACCAAAGGTGTTGTGTGGCGTGGACTACAGCCACGACAAACGGCGGGAGCGA GCCGTGGCCATCGTCCGGCTGGTCCTGGGCTTCCTGTGGCCTCTACTCACGCTCACGATT TGTTACACTTTCATCCTGCTCCGGACGTGGAGCCGCAGGGCCACGCGGTCCACCAAGACA CTCAAGGTGGTGGTGGCAGTGGTGGCCAGTTTCTTTATCTTCTGGTTGCCCTACCAGGTG ACGGGGATAATGATGTCCTTCCTGGAGCCATCGTCACCCACCTTCCTGCTGCTGAATAAG CTGGACTCCCTGTGTGTCTCCTTTGCCTACATCAACTGCTGCATCAACCCCATCATCTAC GTGGTGGCCGGCCAGGGCTTCCAGGGCCGACTGCGGAAATCCCTCCCCAGCCTCCTCCGG AACGTGTTGACTGAAGAGTCCGTGGTTAGGGAGAGCAAGTCATTCACGCGCTCCACAGTG GACACTATGGCCCAGAAGACCCAGGCAGTGTAG Clone variation with respect to NM_001736.3 >OriGene 5' read for NM_001736 unedited
CACATTTTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGGAGACCAGACATG AACTCCTTCAATTATACCACCCCTNGATATGGGCACTATGATGACAAGGATACCCTGGAC CTCAACACCCCTGTGGATAAAACTTCTAACACGCTGCGTGTTCCAGACATCCTGGCCTTG GTCATCTTTGCAGTCGTCTTCCTGGTGGGAGTGCTGGGCAATGCCCTGGTGGTCTGGGTG ACGGCATTCGAGGCCAAGCGGACCATCAATGCCATCTGGTTCCTCAACTTGGCGGTAGCC GACTTCCTCTCCTGCCTGGCGCTGCCCATCTTGTTCACGTCCATTGTACAGCATCACCAC TGGCCCTTTGGCGGGGCCGCCTGCAGCATCCTGCCCTCCCTCATCCTGCTCAACATGTAC GCCAGCATCCTGCTCCTGGCCACCATCAGCGCCGACCGCTTTCTGCTGGTGTTTAAACCC ATCTGGTGCCAGAACTTCCGAGGGGCCGGCTTGGCCTGGATCGCCTGTGCCGTGGCTTGG GGTTTAGCCCTGCTGCTGACCATACCCTCCTTCCTGTACCGGGTGGTCCGGGAGGAGTAC TTTCCACCAAAGGTGTTGTGTGGCGTGGACTACAGCCACGACAAACGGCGGGAGCGAGCC GTGGCCATCGTCCGGCTGGTCCTGGGCTTCCTGTGGCCTCTACTCACGCTCACGATTTGT TACACTTTCATCCTGCTCCGGACGTGGAGCCGCAGGCCACGCGGTCCACCAAGACCTCAA GGTGGTGGTGGCAGTGGTGGGCCAGTTCTTATCTTCTGGGTGCCCTACCAGTGAGGNGAT AATGATGTCCTTCTGGACCATCGTCACCACCTTTCTGCGCTGAATAGCTGACTCCCTGTG TGTCTCTTTTGCTACTCACTGCTGATAACCCATATTTACGGGG >OriGene 3' read for NM_001736 unedited
NGGGGGGNNNGGGGGGGNANNNNNNNCCTCTTTNNNNNNNNNTTTTACTTGNNACCGCGG CCGCATACTAGATCGNGTTTTTTTTTTTTTTTTTTCAAATTCATTTTTATTTTCCTCATT AAAGTCATGTATACTTTTTTTTTAAGCTCAAAACGGTTACATACTATATGATTCCATTGA ATAACATTCTTGAAATGACAACATTATAGAAATGGAGAGTGGATTCCTGGTTGCCAGGGG TTAGGGACACGGCTGGGGTGTGGGGGTGGAGGGAAGTGGGCATCCTGGGGATCCCTGTGG TGATGAAAATGTCCTGTATCTTCACTGTATCAATGTCAATATCCTGGTTATGAGACTACA TTGTAGTTTTGCAAGATGTTGCCATTGGGGGAGGCTGGGTGAAGGGTACACAAAATCCCT CTGTATCATTACTTACAATTGTGTTGAGTTTGCAATGATCTCAAAATAGAAAGCATAATT TAAAAACAAAGTACAAACAAAACTGCAGGTTTTTTAGGTGTTTTTGTTTTTGTTTTTGCT TTGCTTTTGAGACAGAGCCTCCCTCGGTCACCCAGGCTAGAGTGCAGTGGTGCGATCATG GCTCACCACAACCTCCACCTCCAAGGTTCGAGCAATTCTCCCACCTCAGCCTCCCAAGTA GCTGGGATTACAGGCACCCACTACCATGCCCAGTTAATTTTTTGTATTAATGACACAAAA CAGGGGGTTCCACCATGCTNGGCCAACCCTGGNCCTGGAAACTCTTGACCTCAAGGTGAT CCCACCACCTTTAACCTTCCCAAAAGTCTTGGGATTACAGGCCGTGAGGCCACTGCTCTC AACCCTAAATTTTCTTTTNTTAAATTAAACTCACCTTACAAAAGCTTAAAATAACTCCAT GGACCTCCTGTTTTTGCCCCCAAGAAACTTTGGAAATTCCAGTTACCATATTTTCCAACT TGCCCTA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_001736 |
| Insert Size | 2390 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001736.2, NP_001727.1 |
| RefSeq Size | 2328 bp |
| RefSeq ORF | 1053 bp |
| Locus ID | 728 |
| UniProt ID | P21730 |
| Domains | 7tm_1 |
| Protein Families | Druggable Genome, GPCR, Transmembrane |
| Protein Pathways | Complement and coagulation cascades, Neuroactive ligand-receptor interaction |
| Gene Summary | Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a (PubMed:1847994, PubMed:8182049, PubMed:7622471, PubMed:9553099, PubMed:10636859, PubMed:15153520, PubMed:29300009). The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events (PubMed:8182049, PubMed:7622471, PubMed:9553099). Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production (PubMed:10636859, PubMed:15153520).[UniProtKB/Swiss-Prot Function] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC203784 | C5AR1 (Myc-DDK-tagged)-Human complement component 5a receptor 1 (C5AR1) |
CNY 3,656.00 |
|
| RC203784L1 | Lenti ORF clone of Human complement component 5a receptor 1 (C5AR1), Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC203784L2 | Lenti ORF clone of Human complement component 5a receptor 1 (C5AR1), mGFP tagged |
CNY 5,890.00 |
|
| RC203784L3 | Lenti ORF clone of Human complement component 5a receptor 1 (C5AR1), Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC203784L4 | Lenti ORF clone of Human complement component 5a receptor 1 (C5AR1), mGFP tagged |
CNY 6,056.00 |
|
| RG203784 | C5AR1 (tGFP-tagged) - Human complement component 5a receptor 1 (C5AR1) |
CNY 5,256.00 |
|
| SC322253 | C5AR1 (untagged)-Human complement component 5a receptor 1 (C5AR1) |
CNY 3,656.00 |
