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CDA (NM_001785) Human Untagged Clone
CAT＃: SC119015
CDA (untagged)-Human cytidine deaminase (CDA)
CNY 1,800.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CDD |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_001785 edited
ATGGCCCAGAAGCGTCCTGCCTGCACCCTGAAGCCTGAGTGTGTCCAGCAGCTGCTGGTT TGCTCCCAGGAGGCCAAGCAGTCAGCCTACTGCCCCTACAGTCACTTTCCTGTGGGGGCT GCCCTGCTCACCCAGGAGGGGAGAATCTTCAAAGGGTGCAACATAGAAAATGCCTGCTAC CCGCTGGGCATCTGTGCTGAACGGACCGCTATCCAGAAGGCCGTCTCAGAAGGGTACAAG GATTTCAGGGCAATTGCTATCGCCAGTGACATGCAAGATGATTTTATCTCTCCATGTGGG GCCTGCAGGCAAGTCATGAGAGAGTTTGGCACCAACTGGCCCGTGTACATGACCAAGCCG GATGGTACGTATATTGTCATGACGGTCCAGGAGCTGCTGCCCTCCTCCTTTGGGCCTGAG GACCTGCAGAAGACCCAGTGA >OriGene 5' read for NM_001785 unedited
CACGAGGCCCGGGGTACCAACATGGCCCAGAAGCGTCCTGCCTGCACCCTGAAGCCTGAG TGTGTCCAGCAGCTGCTGGTTTGCTCCCAGGAGGCCAAGCAGTCAGCCTACTGCCCCTAC AGTCACTTTCCTGTGGGGGCTGCCCTGCTCACCCAGGAGGGGAGAATCTTCAAAGGGTGC AACATAGAAAATGCCTGCTACCCGCTGGGCATCTGTGCTGAACGGACCGCTATCCAGAAG GCCGTCTCAGAAGGGTACAAGGATTTCAGGGCAATTGCTATCGCCAGTGACATGCAAGAT GATTTTATCTCTCCATGTGGGGCCTGCAGGCAAGTCATGAGAGAGTTTGGCACCAACTGG CCCGTGTACATGACCAAGCCGGATGGTACGTATATTGTCATGACGGTCCAGGAGCTGCTG CCCTCCTCCTTTGGGCCTGAGGACCTGCAGAAGACCCAGTGACAGCCAGAGAATGCCCAC TGCCTGTAACAGCCACCTGGAGAACTTCATAAAGATGTCTCACAGCCCTGGGGACACCTG CCCAGTGGGCCCCAGCCCTACAGGGACTGGGCAAAGATGATGTTTCCAGATTACACTCCA GCCTGAGTCAGCACCCCTCCTAGCAACCTGCCTTGGGA >OriGene 3' read for NM_001785 unedited
CGGCCCCCGGGGGGNNCNNNNNNCNNNNNNNNNNNNNAANNTTTGACTTTGACCCCCCGN CCGCATACNANGATCGNGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT TTTTTTTCCCAGAGGTTCTGGGATGTTTATAATTAAAAAATTGCTCGGAACAGGATAAAA CCTTGGAAAGGCTGATGGGAAACCACCCCAAACTAGGCTGGACTTTAAAAAAGGGCCCCC AGGAAGGAAAGGAAAGGGGGGGCAGGGGGCGGCGGTTTTTTAATCCCCAAGGCAGGTTGT TAGGAGGGGTGCTGACTCAGGCTGGAGGGTAATCTGGAAACATCTTTTTTGCCCAGCCCC TGTAGGGCTGGGGCCCACTGGGCAGGTGTCCCCAGGGCTGGAAAACATTTTTATAAAGTT CTCCAGGGGGCTGTTACAGGCAGGGGGCATTCTTTGGCTGCCACTGGGTCTTTTGCAGGC CCTCAGGCCCAAAGGAGGAGGGCAGCATCTCCTGGACCGTCTTGACAATATACGTCCCAT CCGGCTTGGTCATGTCCACGGCCCAGTTGGGGCCAAACTCTTTAATGACTTGCCTGCAGG CCCCACATGGAAAGATAAAATCATCTTGCATGTCACTGGCAATAGCAATTGCCCTGAAAT CCTTGTACCCTTCTGAAACGGCCCTCTGGATAGCGGCCCGTTCACCACAAATGCCCAGCG GTTAACAGGCATTTTCTATGTTTGCCCCCTTTGAAGATTCTCCTTTCCTGGGGGACCGGG GCACCCCCCCCCAGAAAAGTGACTGTTGGGGCCAATAGGCCTAACTGCTTGGGCCTCCTT GGGACCAAACCACCATTTGTTGGACACCACTTAGCTTTTAGGGTGCAGGCCAGAACCCTT CTTGGGCCCATGGTTGGACCCCCGGGGCCTTCGTGCCCAAATTCCCGGGCCGCCCTTTTG GGGAGCCGTATTACAAAA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_001785 |
| Insert Size | 910 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001785.1, NP_001776.1 |
| RefSeq Size | 892 bp |
| RefSeq ORF | 441 bp |
| Locus ID | 978 |
| UniProt ID | P32320 |
| Domains | dCMP_cyt_deam |
| Protein Families | Stem cell - Pluripotency |
| Protein Pathways | Drug metabolism - other enzymes, Metabolic pathways, Pyrimidine metabolism |
| Gene Summary | This gene encodes an enzyme involved in pyrimidine salvaging. The encoded protein forms a homotetramer that catalyzes the irreversible hydrolytic deamination of cytidine and deoxycytidine to uridine and deoxyuridine, respectively. It is one of several deaminases responsible for maintaining the cellular pyrimidine pool. Mutations in this gene are associated with decreased sensitivity to the cytosine nucleoside analogue cytosine arabinoside used in the treatment of certain childhood leukemias. [provided by RefSeq, Jul 2008] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
APOBEC3A cytidine deaminase induces RNA editing in monocytes and macrophages
,Sharma, S;Patnaik, SK;Thomas Taggart, R;Kannisto, ED;Enriquez, SM;Gollnick, P;Baysal, BE;,
Nat Commun
,PubMed ID 25898173
[CDA]
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