GAB1 (NM_002039) Human Untagged Clone
CAT#: SC118863
GAB1 (untagged)-Human GRB2-associated binding protein 1 (GAB1), transcript variant 2
CNY 5,088.00
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Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | DFNB26 |
Vector | pCMV6-XL5 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene ORF within SC118863 sequence for NM_002039 edited (data generated by NextGen Sequencing)
ATGAGCGGTGGTGAAGTGGTCTGCTCCGGATGGCTCCGCAAGTCCCCCCCGGAGAAAAAG TTGAAGCGTTATGCATGGAAGAGGAGATGGTTCGTGTTACGCAGTGGCCGTTTAACTGGA GATCCAGATGTTTTGGAATATTACAAAAATGATCATGCCAAGAAGCCTATTCGTATTATT GATTTAAATTTATGTCAACAAGTAGATGCTGGATTGACATTTAACAAAAAAGAGTTTGAA AACAGCTACATTTTTGATATCAACACTATTGACCGGATTTTCTACTTGGTAGCAGACAGC GAGGAGGAGATGAATAAGTGGGTTCGTTGTATTTGTGACATCTGTGGGTTTAATCCAACA GAAGAAGATCCTGTGAAGCCACCTGGCAGCTCTTTACAAGCACCAGCTGATTTACCTTTA GCTATAAATACAGCACCACCATCCACCCAGGCAGATTCATCCTCTGCTACTCTACCTCCT CCATATCAGCTAATCAATGTTCCACCACACCTGGAAACTCTTGGCATTCAGGAGGATCCT CAAGACTACCTGTTGCTCATCAACTGTCAAAGCAAGAAGCCCGAACCCACCAGAACGCAT GCTGATTCTGCAAAATCCACCTCTTCTGAAACAGACTGCAATGATAACGTCCCTTCTCAT AAAAATCCTGCTTCCTCCCAGAGCAAACATGGAATGAATGGCTTTTTTCAGCAGCAAATG ATATACGACTCTCCACCTTCACGTGCCCCATCTGCTTCAGTTGACTCCAGCCTTTATAAC CTGCCCAGGAGTTATTCCCATGATGTTTTACCAAAGGTGTCTCCATCAAGTACTGAAGCA GATGGAGAACTCTATGTTTTTAATACCCCATCTGGGACATCGAGTGTAGAGACTCAAATG AGGCATGTATCTATTAGTTATGACATTCCTCCAACACCTGGTAATACTTATCAGATTCCA CGAACATTTCCAGAAGGAACCTTGGGACAGACATCAAAGCTAGACACTATTCCAGATATT CCTCCACCTCGGCCACCGAAACCACATCCAGCTCATGACCGATCTCCTGTGGAAACGTGT AGTATCCCACGCACCGCCTCAGACACTGACAGTAGTTACTGTATCCCTACAGCAGGGATG TCGCCTTCACGTAGTAATACCATTTCCACTGTGGATTTAAACAAATTGCGAAAAGATGCT AGTTCTCAAGACTGCTATGATATTCCACGAGCATTTCCAAGTGATAGATCTAGTTCACTT GAAGGCTTCCATAACCACTTTAAAGTCAAAAATGTGTTGACAGTGGGAAGTGTTTCAAGT GAAGAACTGGATGAAAATTACGTCCCAATGAATCCCAATTCACCACCACGACAACATTCC AGCAGTTTTACAGAACCAATTCAGGAAGCAAATTATGTGCCAATGACTCCAGGAACATTT GATTTTTCCTCATTTGGAATGCAAGTTCCTCCTCCTGCTCATATGGGCTTCAGGTCCAGC CCAAAAACCCCTCCCAGAAGGCCAGTTCCTGTTGCAGACTGTGAACCACCCCCCGTGGAT AGGAACCTCAAGCCAGACAGAAAAGTCAAGCCAGCGCCTTTAGAAATAAAACCTTTGCCA GAATGGGAAGAATTACAAGCCCCAGTTAGATCTCCCATCACTAGGAGTTTTGCTCGAGAC TCTTCCAGGTTTCCCATGTCCCCCCGACCAGATTCAGTGCATAGCACAACTTCAAGCAGT GACTCACACGACAGTGAAGAGAATTATGTTCCCATGAACCCAAACCTGTCCAGTGAAGAC CCAAATCTCTTTGGCAGTAACAGTCTTGATGGAGGAAGCAGCCCTATGATCAAGCCCAAA GGAGACAAACAGGTGGAATACTTAGATCTCGACTTAGATTCTGGGAAATCCACACCACCA CGTAAGCAAAAGAGCAGTGGCTCAGGCAGCAGTGTAGCAGATGAGAGAGTGGATTATGTT GTTGTTGACCAACAGAAGACCTTGGCTCTAAAGAGTACCCGGGAAGCCTGGACAGATGGG AGACAGTCCACAGAATCAGAAACGCCAGCGAAGAGTGTGAAATGA Clone variation with respect to NM_002039.3 >OriGene 5' read for NM_002039 unedited
TTCGCATTATGTAATACGACTCACTATAGGGCGGCCGCGNAATTCGCACGAGGCTGAGTC CGAGCGCTGCTGAGGCAGCTGGCGAGACGGCACGTCTGGAGGCGAGGCGGGCGCACTGAA AGGAGGCCGGCGCGCCCGCGGCCCCGGCTCGCGTTCTGTTCAGGTTCGTGGGCCTGCAGA GGAGAGACTCGAACTCGTGGAACCCGCGCACCGTGGAGTCTGTCCGCCCAGTCCGTCCGG GGTGCGCGACCAGGAGAGCTAGGTTCTCGCCACTGCGCGCTCGGCAGGCGTCGGCTGTGT CGGGAGCGCGCCCGCCGCCCCTCAGCTGCCCGGCCCGGAGCCCGAGACGCGCGCACCATG AGCGGTGGTGAAGTGGTCTGCTCCGGATGGCTCCGCAAGTCCCCCCCGGAGAAAAAGTTG AAGCGTTATGCATGGAAGAGGAGATGGTTCGTGTTACGCAGTGGCCGTTTAACTGGAGAT CCAGATGTTTTGGAATATTACAAAAATGATCATGCCAAGAAGCCTATTCGTATTATTGAT TTAAATTTATGTCAACAAGTAGATGCTGGATTGACATTTAACAAAAAAGAGTTTGAAAAC AGCTACATTTTTGATATCAACACTATTGACCGGATTTTCTACTTGGTAGCAGACAGCGAG GAGGAGATGAATAAGTGGGTTCGTTGTATTTGTGACATCTGTGGGTTTAATCCAACAGAA GAAGATCCTGTGAAGCCACCTGGCAGCTCTTTACAGCACCAGCTGAATTACCTTTAGCTT AAATACAGCACCACCATTCCACCCAGCAGATTCATNCTCTGCTACTCTACCTNCTTCATA TTAGCTAATCAATGGTCCACCACACCTGGAAACTTTTGGCATTCCAGGAGATCCTCAAGA CTACCTGNTGCTCATTAACTGGNAAAGCAGAAGCCCGGACCCCCAGGACGCATGCTGGAT CTGT >OriGene 3' read for NM_002039 unedited
CCCCATGGAATGGCACTTCCAGGNCCAGGNAAAGCACTGGGGNAGGGTCACAGGNATGCC ACCCGGGATCTGTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAGAGTCGAGTTTTTT TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTCAGGTTAAAATGCTTTTATGA AGGAAAACTATAACCCCCATTAATTAAATATAAAAAAGTCCAGCAAAATTTATGACCTTA ATGTACAAGTAAAGTAGTTTTTCTATATCAAATTAAATTTAGCCTATGATTAAATACAAG GCTTTTTATCCCCCCCCTTCCGGACCCCCTCATAGTACCTTTAGGGAATTCTCTAAAAGG CTCACAGTACCTTATATAGTATTGATAAGGAAAAAAATGTATAAACTGAAGGGTAAATTT AAAAAATCTTTTACATCTTACTAAATGATATCTTCCAGGGGTTAAACAGCTTTTTCAAGT TTGAATTTTAATTTTTGAAAGCAAAACTGGGCTTCAGTATTCAAACCTTCATAAAATCTT ACATTTTTTCAAAATAAGGAATTAAGGTAAAAAACTCTAATGGGGAAAAAAGATTTCCAA TCTCCAAAATCATAACTGTCACATCGTTAACCAGGGGTTTTTAGCCCATTCCTGGCCAAA GTCTAGCTTCTTGGAGGTGAGTTAAAAGGGTTTGATTCAAATTTAGTTTTTATACGTGCA TATTTAAAAACCTAATAAACCCCACATTCTGATGTGTAACATACCCTACTTTACCAACTG GAGACTGCTTATTTATTAACTTCCCCTACCAGGATAACTTTATTTGGGATAGACCCTGAA AAACTTTAGCTATCTCCAAATTAAAGAATTTCCTGGAATGGATGGTTAAAACCCATTAAT TTTCGCCAACATTG |
Restriction Sites | NotI-NotI |
ACCN | NM_002039 |
Insert Size | 4700 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_002039.2, NP_002030.2 |
RefSeq Size | 3323 bp |
RefSeq ORF | 2085 bp |
Locus ID | 2549 |
UniProt ID | Q13480 |
Domains | PH |
Protein Families | Druggable Genome |
Protein Pathways | ErbB signaling pathway, Neurotrophin signaling pathway, Renal cell carcinoma |
Gene Summary | The protein encoded by this gene is a member of the IRS1-like multisubstrate docking protein family. It is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008] Transcript Variant: This variant (2) lacks an in-frame coding exon compared to variant 1, resulting in a shorter isoform (b) with the same N- and C-termini, but missing a 30 aa protein segment compared to isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. |
Documents
Product Manuals |
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SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC219005 | GAB1 (Myc-DDK-tagged)-Human GRB2-associated binding protein 1 (GAB1), transcript variant 2 |
CNY 5,088.00 |
|
RC219005L1 | Lenti ORF clone of Human GRB2-associated binding protein 1 (GAB1), transcript variant 2, Myc-DDK-tagged |
CNY 9,220.00 |
|
RC219005L2 | Lenti ORF clone of Human GRB2-associated binding protein 1 (GAB1), transcript variant 2, mGFP tagged |
CNY 9,220.00 |
|
RC219005L3 | Lenti ORF clone of Human GRB2-associated binding protein 1 (GAB1), transcript variant 2, Myc-DDK-tagged |
CNY 9,220.00 |
|
RC219005L4 | Lenti ORF clone of Human GRB2-associated binding protein 1 (GAB1), transcript variant 2, mGFP tagged |
CNY 9,220.00 |
|
RG219005 | GAB1 (tGFP-tagged) - Human GRB2-associated binding protein 1 (GAB1), transcript variant 2 |
CNY 6,688.00 |