GAB1 (NM_002039) Human Untagged Clone

CAT#: SC118863

GAB1 (untagged)-Human GRB2-associated binding protein 1 (GAB1), transcript variant 2



  "NM_002039" in other vectors (6)

CNY 5,088.00


货期*
现货

规格
    • 10 ug

Product images

经常一起买 (4)
Rabbit Polyclonal Anti-GAB1 Antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00


TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Synonyms DFNB26
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC118863 sequence for NM_002039 edited (data generated by NextGen Sequencing)
ATGAGCGGTGGTGAAGTGGTCTGCTCCGGATGGCTCCGCAAGTCCCCCCCGGAGAAAAAG
TTGAAGCGTTATGCATGGAAGAGGAGATGGTTCGTGTTACGCAGTGGCCGTTTAACTGGA
GATCCAGATGTTTTGGAATATTACAAAAATGATCATGCCAAGAAGCCTATTCGTATTATT
GATTTAAATTTATGTCAACAAGTAGATGCTGGATTGACATTTAACAAAAAAGAGTTTGAA
AACAGCTACATTTTTGATATCAACACTATTGACCGGATTTTCTACTTGGTAGCAGACAGC
GAGGAGGAGATGAATAAGTGGGTTCGTTGTATTTGTGACATCTGTGGGTTTAATCCAACA
GAAGAAGATCCTGTGAAGCCACCTGGCAGCTCTTTACAAGCACCAGCTGATTTACCTTTA
GCTATAAATACAGCACCACCATCCACCCAGGCAGATTCATCCTCTGCTACTCTACCTCCT
CCATATCAGCTAATCAATGTTCCACCACACCTGGAAACTCTTGGCATTCAGGAGGATCCT
CAAGACTACCTGTTGCTCATCAACTGTCAAAGCAAGAAGCCCGAACCCACCAGAACGCAT
GCTGATTCTGCAAAATCCACCTCTTCTGAAACAGACTGCAATGATAACGTCCCTTCTCAT
AAAAATCCTGCTTCCTCCCAGAGCAAACATGGAATGAATGGCTTTTTTCAGCAGCAAATG
ATATACGACTCTCCACCTTCACGTGCCCCATCTGCTTCAGTTGACTCCAGCCTTTATAAC
CTGCCCAGGAGTTATTCCCATGATGTTTTACCAAAGGTGTCTCCATCAAGTACTGAAGCA
GATGGAGAACTCTATGTTTTTAATACCCCATCTGGGACATCGAGTGTAGAGACTCAAATG
AGGCATGTATCTATTAGTTATGACATTCCTCCAACACCTGGTAATACTTATCAGATTCCA
CGAACATTTCCAGAAGGAACCTTGGGACAGACATCAAAGCTAGACACTATTCCAGATATT
CCTCCACCTCGGCCACCGAAACCACATCCAGCTCATGACCGATCTCCTGTGGAAACGTGT
AGTATCCCACGCACCGCCTCAGACACTGACAGTAGTTACTGTATCCCTACAGCAGGGATG
TCGCCTTCACGTAGTAATACCATTTCCACTGTGGATTTAAACAAATTGCGAAAAGATGCT
AGTTCTCAAGACTGCTATGATATTCCACGAGCATTTCCAAGTGATAGATCTAGTTCACTT
GAAGGCTTCCATAACCACTTTAAAGTCAAAAATGTGTTGACAGTGGGAAGTGTTTCAAGT
GAAGAACTGGATGAAAATTACGTCCCAATGAATCCCAATTCACCACCACGACAACATTCC
AGCAGTTTTACAGAACCAATTCAGGAAGCAAATTATGTGCCAATGACTCCAGGAACATTT
GATTTTTCCTCATTTGGAATGCAAGTTCCTCCTCCTGCTCATATGGGCTTCAGGTCCAGC
CCAAAAACCCCTCCCAGAAGGCCAGTTCCTGTTGCAGACTGTGAACCACCCCCCGTGGAT
AGGAACCTCAAGCCAGACAGAAAAGTCAAGCCAGCGCCTTTAGAAATAAAACCTTTGCCA
GAATGGGAAGAATTACAAGCCCCAGTTAGATCTCCCATCACTAGGAGTTTTGCTCGAGAC
TCTTCCAGGTTTCCCATGTCCCCCCGACCAGATTCAGTGCATAGCACAACTTCAAGCAGT
GACTCACACGACAGTGAAGAGAATTATGTTCCCATGAACCCAAACCTGTCCAGTGAAGAC
CCAAATCTCTTTGGCAGTAACAGTCTTGATGGAGGAAGCAGCCCTATGATCAAGCCCAAA
GGAGACAAACAGGTGGAATACTTAGATCTCGACTTAGATTCTGGGAAATCCACACCACCA
CGTAAGCAAAAGAGCAGTGGCTCAGGCAGCAGTGTAGCAGATGAGAGAGTGGATTATGTT
GTTGTTGACCAACAGAAGACCTTGGCTCTAAAGAGTACCCGGGAAGCCTGGACAGATGGG
AGACAGTCCACAGAATCAGAAACGCCAGCGAAGAGTGTGAAATGA

Clone variation with respect to NM_002039.3
>OriGene 5' read for NM_002039 unedited
TTCGCATTATGTAATACGACTCACTATAGGGCGGCCGCGNAATTCGCACGAGGCTGAGTC
CGAGCGCTGCTGAGGCAGCTGGCGAGACGGCACGTCTGGAGGCGAGGCGGGCGCACTGAA
AGGAGGCCGGCGCGCCCGCGGCCCCGGCTCGCGTTCTGTTCAGGTTCGTGGGCCTGCAGA
GGAGAGACTCGAACTCGTGGAACCCGCGCACCGTGGAGTCTGTCCGCCCAGTCCGTCCGG
GGTGCGCGACCAGGAGAGCTAGGTTCTCGCCACTGCGCGCTCGGCAGGCGTCGGCTGTGT
CGGGAGCGCGCCCGCCGCCCCTCAGCTGCCCGGCCCGGAGCCCGAGACGCGCGCACCATG
AGCGGTGGTGAAGTGGTCTGCTCCGGATGGCTCCGCAAGTCCCCCCCGGAGAAAAAGTTG
AAGCGTTATGCATGGAAGAGGAGATGGTTCGTGTTACGCAGTGGCCGTTTAACTGGAGAT
CCAGATGTTTTGGAATATTACAAAAATGATCATGCCAAGAAGCCTATTCGTATTATTGAT
TTAAATTTATGTCAACAAGTAGATGCTGGATTGACATTTAACAAAAAAGAGTTTGAAAAC
AGCTACATTTTTGATATCAACACTATTGACCGGATTTTCTACTTGGTAGCAGACAGCGAG
GAGGAGATGAATAAGTGGGTTCGTTGTATTTGTGACATCTGTGGGTTTAATCCAACAGAA
GAAGATCCTGTGAAGCCACCTGGCAGCTCTTTACAGCACCAGCTGAATTACCTTTAGCTT
AAATACAGCACCACCATTCCACCCAGCAGATTCATNCTCTGCTACTCTACCTNCTTCATA
TTAGCTAATCAATGGTCCACCACACCTGGAAACTTTTGGCATTCCAGGAGATCCTCAAGA
CTACCTGNTGCTCATTAACTGGNAAAGCAGAAGCCCGGACCCCCAGGACGCATGCTGGAT
CTGT
>OriGene 3' read for NM_002039 unedited
CCCCATGGAATGGCACTTCCAGGNCCAGGNAAAGCACTGGGGNAGGGTCACAGGNATGCC
ACCCGGGATCTGTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAGAGTCGAGTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTCAGGTTAAAATGCTTTTATGA
AGGAAAACTATAACCCCCATTAATTAAATATAAAAAAGTCCAGCAAAATTTATGACCTTA
ATGTACAAGTAAAGTAGTTTTTCTATATCAAATTAAATTTAGCCTATGATTAAATACAAG
GCTTTTTATCCCCCCCCTTCCGGACCCCCTCATAGTACCTTTAGGGAATTCTCTAAAAGG
CTCACAGTACCTTATATAGTATTGATAAGGAAAAAAATGTATAAACTGAAGGGTAAATTT
AAAAAATCTTTTACATCTTACTAAATGATATCTTCCAGGGGTTAAACAGCTTTTTCAAGT
TTGAATTTTAATTTTTGAAAGCAAAACTGGGCTTCAGTATTCAAACCTTCATAAAATCTT
ACATTTTTTCAAAATAAGGAATTAAGGTAAAAAACTCTAATGGGGAAAAAAGATTTCCAA
TCTCCAAAATCATAACTGTCACATCGTTAACCAGGGGTTTTTAGCCCATTCCTGGCCAAA
GTCTAGCTTCTTGGAGGTGAGTTAAAAGGGTTTGATTCAAATTTAGTTTTTATACGTGCA
TATTTAAAAACCTAATAAACCCCACATTCTGATGTGTAACATACCCTACTTTACCAACTG
GAGACTGCTTATTTATTAACTTCCCCTACCAGGATAACTTTATTTGGGATAGACCCTGAA
AAACTTTAGCTATCTCCAAATTAAAGAATTTCCTGGAATGGATGGTTAAAACCCATTAAT
TTTCGCCAACATTG
Restriction Sites NotI-NotI     
ACCN NM_002039
Insert Size 4700 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq NM_002039.2, NP_002030.2
RefSeq Size 3323 bp
RefSeq ORF 2085 bp
Locus ID 2549
UniProt ID Q13480
Domains PH
Protein Families Druggable Genome
Protein Pathways ErbB signaling pathway, Neurotrophin signaling pathway, Renal cell carcinoma
Gene Summary The protein encoded by this gene is a member of the IRS1-like multisubstrate docking protein family. It is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
Transcript Variant: This variant (2) lacks an in-frame coding exon compared to variant 1, resulting in a shorter isoform (b) with the same N- and C-termini, but missing a 30 aa protein segment compared to isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments.
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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