ID2 (NM_002166) Human Untagged Clone

CAT#: SC118791

ID2 (untagged)-Human inhibitor of DNA binding 2, dominant negative helix-loop-helix protein (ID2)



  "NM_002166" in other vectors (6)

CNY 1,800.00


货期*
现货

规格
    • 10 ug

Product images

经常一起买 (3)
ID2 mouse monoclonal antibody, clone OTI10C3 (formerly 10C3)
    • 100 ul

CNY 1,999.00
CNY 2,700.00


TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Synonyms bHLHb26; GIG8; ID2A; ID2H
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC118791 sequence for NM_002166 edited (data generated by NextGen Sequencing)
ATGAAAGCCTTCAGTCCCGTGAGGTCCGTTAGGAAAAACAGCCTGTCGGACCACAGCCTG
GGCATCTCCCGGAGCAAAACCCCTGTGGACGACCCGATGAGCCTGCTATACAACATGAAC
GACTGCTACTCCAAGCTCAAGGAGCTGGTGCCCAGCATCCCCCAGAACAAGAAGGTGAGC
AAGATGGAAATCCTGCAGCACGTCATCGACTACATCTTGGACCTGCAGATCGCCCTGGAC
TCGCATCCCACTATTGTCAGCCTGCATCACCAGAGACCCGGGCAGAACCAGGCGTCCAGG
ACGCCGCTGACCACCCTCAACACGGATATCAGCATCCTGTCCTTGCAGGCTTCTGAATTC
CCTTCTGAGTTAATGTCAAATGACAGCAAAGCACTGTGTGGCTGA

Clone variation with respect to NM_002166.4
>OriGene 5' read for NM_002166 unedited
GATTTTGTAATACGACTTTCTATAGGCGCGCCGCGAATTCGCACGAGGCCGGTGCCATTC
GCAGCTAGCTCAGCAGGCGGCAGCGGCGGCCTGAGCTTCAGGGACTGCCAGCTCCCTCCC
GGTCTCGCCTTCCCTCGCGGTCAGCATGAAAGCCTTCAGTCCCGTGAGGTCCGTTAGGAA
AAACAGCCTGTCGGACCACAGCCTGGGCATCTCCCGGAGCAAAACCCCTGTGGACGACCC
GATGAGCCTGCTATACAACATGAACGACTGCTACTCCAAGCTCAAGGAGCTGGTGCCCAG
CATCCCCCAGAACAAGAAGGTGAGCAAGATGGAAATCCTGCAGCACGTCATCAACTACAT
CTTGGACCTGCAGATCGCCCTGGACTCGCATCCCACTATTGTCAGCCTGCATCACCAGAG
ACCCGGGCAGAACCAGGCGTNCAGGACGCCGCTGACCACCCTCAACACGGATATCAGCAT
CCTGTCCTTGCAGGCTTCTGAATTCCCTTCTGAGTTAATGTCAAATGACAGCAAAGCACT
GTGTGGCTGAATAAGCGGCGTTCATGACTTCTTTTATTCTTTGCACAACAACAACAACAA
CAAATTCACGGAATCTTTTAAGTGCTGACCTATATTTTTCAACCATCTTCCCCACGACGA
CAAGTTGAATGGACCTTTTTAAAAAGAAAACAAAAATGGAAGGAACACTAAGAATGATCA
CTCTTCCCAGGGTGTCCTCTTACTTGCACTGTGATATTCCGTATTTATGAAAAAGACTTT
TAAATGCCCTTTCTGCAGTTGGAAGGGTCTCCTTTATATACTATTCCCACCATGGGGAAG
CGAAAACGGTTAACATCACCAGGAATTGCCCAATCTTAGCCAGACTTTGCCCTCTTTTCA
AAGGTGGAGCCGTGAATACCATNAAGGTATCCAGTTTCCAACCCTTAAAATGAAGGCTTN
TGGTCACGAAATTCCCTTCTTGACACAACCTTAG
>OriGene 3' read for NM_002166 unedited
NNNNNNNNCCCCCCCCNCCCGCCCCCNTNCNGGGTTTGCNTTGCCCGGCGCCGCATTTCA
CGATCGGTTTTTTTTTTTTTTTTTTNTGATTCAGAACTGTTTTATTATAATCTTATACAG
TCTACATAAATTTGAACTTGCATTTATTTGGGTTCAGCTATAACATAGCATAATATAAAT
CAAAGCACTGGCCCTCTGAAACAAAGCAGGCACTCACCATTCACTAAACACCCTTGACTT
ATTTTGTATAAAAGGGTTAAGTTTACCACTCAACTTTCATACAAAGTTCACCATGAATAA
GCACATCATTACCCTTTTGAATGCAGAAATAGACATCTCTGCCACTATACAACACAACTC
TAATTAACCAGCTCACAACGGTTTCACCTCAAATAGATATATTTATCCCTAAATATATAC
ACAGCACTCAGCCGGCTTGTGTCACAAAAGGTAATTTCTGACCAAAAGACTTCATTTCAC
TGCCCGAACTCCTGGATCCTTCTGCCATTCACGCTCCACCTTTGAAAAAAGGCAAAGTCT
GCTTACATTGGGCCATTCCTCTGTGATCCTAACGCTCTCGCTCCCCATGGTGGGAATAGT
ATATAAACAAAATCTTCCACCTGCCGACAGGCCCTCTCCCCAACGCCTTTCTCATACCCA
CCGAAATATCACAGCCCCACGCAAGAAAACCCCCTGCCAAGATGAACATTCCTAACCCTC
CCTTCATTCTTTCTTTTTTTTTCAAACCCGGTCCATTCCACCCGTCCCTCCTTGCGAAAG
GCTCCCCAAATCATCCCCACCCTTCCCCATTCCCCCGAATTCCTCGTTCCCCCCTGTCCC
CCCCAAAACAAAAAACCCCCCCACCCCGCTCATTCACCACCACCGGCGCTTTGCTGTATT
TGTCCCCACCCTCAACGGCACTTTAAAACCCGCCAGGCC
Restriction Sites NotI-NotI     
ACCN NM_002166
Insert Size 1280 bp
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq NM_002166.4, NP_002157.2
RefSeq Size 1402 bp
RefSeq ORF 405 bp
Locus ID 3398
UniProt ID Q02363
Domains HLH
Protein Families ES Cell Differentiation/IPS, Stem cell relevant signaling - TGFb/BMP signaling pathway, Transcription Factors
Protein Pathways TGF-beta signaling pathway
Gene Summary The protein encoded by this gene belongs to the inhibitor of DNA binding family, members of which are transcriptional regulators that contain a helix-loop-helix (HLH) domain but not a basic domain. Members of the inhibitor of DNA binding family inhibit the functions of basic helix-loop-helix transcription factors in a dominant-negative manner by suppressing their heterodimerization partners through the HLH domains. This protein may play a role in negatively regulating cell differentiation. A pseudogene of this gene is located on chromosome 3. [provided by RefSeq, Aug 2011]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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