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MEF2C (NM_002397) Human Untagged Clone
CAT＃: SC118667
MEF2C (untagged)-Human myocyte enhancer factor 2C (MEF2C), transcript variant 1
CNY 5,488.00
| Cited in 1 publication. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | C5DELq14.3; DEL5q14.3 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_002397, the custom clone sequence may differ by one or more nucleotides
ATGGGGAGAAAAAAGATTCAGATTACGAGGATTATGGATGAACGTAACAGACAGGTGACATTTACAAAGA GGAAATTTGGGTTGATGAAGAAGGCTTATGAGCTGAGCGTGCTGTGTGACTGTGAGATTGCGCTGATCAT CTTCAACAGCACCAACAAGCTGTTCCAGTATGCCAGCACCGACATGGACAAAGTGCTTCTCAAGTACACG GAGTACAACGAGCCGCATGAGAGCCGGACAAACTCAGACATCGTGGAGACGTTGAGAAAGAAGGGCCTTA ATGGCTGTGACAGCCCAGACCCCGATGCGGACGATTCCGTAGGTCACAGCCCTGAGTCTGAGGACAAGTA CAGGAAAATTAACGAAGATATTGATCTAATGATCAGCAGGCAAAGATTGTGTGCTGTTCCACCTCCCAAC TTCGAGATGCCAGTCTCCATCCCAGTGTCCAGCCACAACAGTTTGGTGTACAGCAACCCTGTCAGCTCAC TGGGAAACCCCAACCTATTGCCACTGGCTCACCCTTCTCTGCAGAGGAATAGTATGTCTCCTGGTGTAAC ACATCGACCTCCAAGTGCAGGTAACACAGGTGGTCTGATGGGTGGAGACCTCACGTCTGGTGCAGGCACC AGTGCAGGGAACGGGTATGGCAATCCCCGAAACTCACCAGGTCTGCTGGTCTCACCTGGTAACTTGAACA AGAATATGCAAGCAAAATCTCCTCCCCCAATGAATTTAGGAATGAATAACCGTAAACCAGATCTCCGAGT TCTTATTCCACCAGGCAGCAAGAATACGATGCCATCAGTGTCTGAGGATGTCGACCTGCTTTTGAATCAA AGGATAAATAACTCCCAGTCGGCTCAGTCATTGGCTACCCCAGTGGTTTCCGTAGCAACTCCTACTTTAC CAGGACAAGGAATGGGAGGATATCCATCAGCCATTTCAACAACATATGGTACCGAGTACTCTCTGAGTAG TGCAGACCTGTCATCTCTGTCTGGGTTTAACACCGCCAGCGCTCTTCACCTTGGTTCAGTAACTGGCTGG CAACAGCAACACCTACATAACATGCCACCATCTGCCCTCAGTCAGTTGGGAGCTTGCACTAGCACTCATT TATCTCAGAGTTCAAATCTCTCCCTGCCTTCTACTCAAAGCCTCAACATCAAGTCAGAACCTGTTTCTCC TCCTAGAGACCGTACCACCACCCCTTCGAGATACCCACAACACACGCGCCACGAGGCGGGGAGATCTCCT GTTGACAGCTTGAGCAGCTGTAGCAGTTCGTACGACGGGAGCGACCGAGAGGATCACCGGAACGAATTCC ACTCCCCCATTGGACTCACCAGACCTTCGCCGGACGAAAGGGAAAGTCCCTCAGTCAAGCGCATGCGACT TTCTGAAGGATGGGCAACATGA >OriGene 5' read for NM_002397 unedited
NGTCAGAATTTGTATACGACTCATATAGGGCGGCCGCGAATTCGCACGAGGGTTTGGAGG AACAGGAAAGAGAAAGAAAGGAAGGAAATAATACTAATTTCAGGGACGAGAGAGAGAAGA AAAACGGGGACTATGGGGAGAAAAAAGATTCAGATTACGAGGATTATGGATGAACGTAAC AAACAGGTGACATTTACAAAGAGGAAATTTGGGTTGATGAAGAAGGCTTATGAGCTGAGC GTGCTGTGTGACTGTGAGATTGCGCTGATCATCTTCAACAGCACCAACAAGCTGTTCCAG TATGCCAGCACCGACATGGACAAAGTGCTTCTCAAGTACACGGAGTACAACGAGCCGCAT GAGAGCCGGACAAACTCAGACATCGTGGAGACGTTGAGAAAGAAGGGCCTTAATGGCTGT GACAGCCCAGACCCCGATGCGGACGATTCCGTAGGTCACAGCCCTGAGTCTGAGGACAAG TACAGGAAAATTAACGAAGATATTGATCTAATGATCAGCAGGCAAAGATTGTGTGCTGTT CCACCTCCCAACTTCGAGATGCCAGTCTCCATCCCAGTGTCCAGCCACAACAGTTTGGTG TACAGCAACCCTGTCAGCTCACTGGGAAACCCCAACCTATTGCCACTGGCTCACCCTATT CTGCAGAGGAATAGTATGTCTCCTGGTGTAACACATCGACCTCCAAGTGCAGGTAACACA GGGTGGTCTGATGGGTGGAGACCTCACGTCTGGTGCAGGCACCAGTGCAGGGAACGGGTA TGGCAATTCCCGAATCTCACCAAGTCTGCTGGTCTCACCTGGTAACTGAACAAAATATGC AAGCACAATTTCTTCCCAATGATTTAGGAAGAATACCGTAACCAGTCTCCGAGTCTATAC A >OriGene 3' read for NM_002397 unedited
TTTTAATATATAACACACATTNAGGNTCACNANAGGGNCCAAGGCTAGCATCCTTTATGG ATACAACCAAAGGTGCATTGTGGTCTAATTGTGGATTTCAGATCAAGTTAAGNAAAAATA TAGCCTAGTTAATAAGGTCTCTTGGCTTCTGCCACCCAGCGGCAGCCTTTTACCAAAAAT GGGNNNAGAAACACATAAGCAACTATGCAAGTAANANAAAGNNAAAAAAAAATGGATNNN NNNNNNNNNNAATGTNCTACNCNNNCCCNNNNTNNNNNNATNNNNNNANNNCACAGGTGG ATATTACTGGCTATATCTNCTTTGCTGGGTATGTCAATGCATATGATTGGAGATGAATCG ACAGATCTTCACATTCCAAGAGAAGGAAAATCTTTCCTAGACTGAAATATCTTTTAAACA ATATATATTGACTTTCTTATGGCACTCACTTATTAAAGGGTCTGAAAATAATCCCTTATA GACGAATATTANACAAGAGTCATTTTTTTTAATTAAAAAAAGGGACATAGAGAGGGTTCT TATGGGATTTCTTGAAATGGCTATTAAATCTCTTTATTTGAGAAAAAATAGATGACATAC ATGCTNTATGCANAAGTGACATTTGGGGGGTCCTGACACACCCGGGATTNGTCAACAGTC CTATATTGCTGACAAGATTGTCAAGGGTCANTTAAAAATATTTAAAACGGATGACAAAAC AACTATCCCTTTACCTGGCTTCTTTCTTGGCTAGCACCCAATCTTTTAAATTTTNTCTTC TGTGGGGAATTATAACCTTATTCACCCAAGTAAATTCCATATCACCTTGTTCCTAAGGCC ATTATTGCAGGAATTGGCCCCCAACTTAACTTTTTTTTTTGGGCATTTTTTAAAAACCTT TAAATTTTAGGTTGAAACACCCGATATTTTAAATTGGGCAGTTAGAATTGGCCTTCCGAA TCCAAAAGCTGGG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_002397 |
| Insert Size | 4000 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_002397.2, NP_002388.2 |
| RefSeq Size | 4077 bp |
| RefSeq ORF | 1422 bp |
| Locus ID | 4208 |
| UniProt ID | Q06413 |
| Domains | MADS |
| Protein Families | Transcription Factors |
| Protein Pathways | MAPK signaling pathway |
| Gene Summary | This locus encodes a member of the MADS box transcription enhancer factor 2 (MEF2) family of proteins, which play a role in myogenesis. The encoded protein, MEF2 polypeptide C, has both trans-activating and DNA binding activities. This protein may play a role in maintaining the differentiated state of muscle cells. Mutations and deletions at this locus have been associated with severe cognitive disability, stereotypic movements, epilepsy, and cerebral malformation. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2010] Transcript Variant: This variant (1) represents the longest transcript and encodes isoform 1. Variants 1, 6, and 9-11 all encode the same isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Control of the SOST Bone Enhancer by PTH Using MEF2 Transcription Factors
,Olivier Leupin, Ina Kramer, Nicole M Collette, Gabriela G Loots, François Natt, Michaela Kneissel, Hansjoerg Keller,
Journal of Bone and Mineral Research, Journal of Bone and Mineral Research December 2007:22:1957-1967 (doi: 10.1359/jbmr.070804)
[MEF2C]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC220584 | MEF2C (Myc-DDK-tagged)-Human myocyte enhancer factor 2C (MEF2C), transcript variant 1 |
CNY 5,488.00 |
|
| RC220584L1 | Lenti ORF clone of Human myocyte enhancer factor 2C (MEF2C), transcript variant 1, Myc-DDK-tagged |
CNY 7,888.00 |
|
| RC220584L2 | Lenti ORF clone of Human myocyte enhancer factor 2C (MEF2C), transcript variant 1, mGFP tagged |
CNY 7,888.00 |
|
| RC220584L3 | Lenti ORF clone of Human myocyte enhancer factor 2C (MEF2C), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC220584L4 | Lenti ORF clone of Human myocyte enhancer factor 2C (MEF2C), transcript variant 1, mGFP tagged |
CNY 7,888.00 |
|
| RG220584 | MEF2C (tGFP-tagged) - Human myocyte enhancer factor 2C (MEF2C), transcript variant 1 |
CNY 7,088.00 |
