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MTAP (NM_002451) Human Untagged Clone
CAT＃: SC118635
MTAP (untagged)-Human methylthioadenosine phosphorylase (MTAP)
CNY 2,400.00
CNY 2,950.00
| Cited in 2 publications. |
Product images
热销推荐Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | BDMF; c86fus; DMSFH; DMSMFH; HEL-249; LGMBF; MSAP |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC118635 sequence for NM_002451 edited (data generated by NextGen Sequencing)
ATGGCCTCTGGCACCACCACCACCGCCGTGAAGATTGGAATAATTGGTGGAACAGGCCTG GATGATCCAGAAATTTTAGAAGGAAGAACTGAAAAATATGTGGATACTCCATTTGGCAAG CCATCTGATGCCTTAATTTTGGGGAAGATAAAAAATGTTGATTGCATCCTCCTTGCAAGG CATGGAAGGCAGCACACCATCATGCCTTCAAAGGTCAACTACCAGGCGAACATCTGGGCT TTGAAGGAAGAGGGCTGTACACATGTCATAGTGACCACAGCTTGTGGCTCCTTGAGGGAG GAGATTCAGCCCGGCGATATTGTCATTATTGATCAGTTCATTGACAGGACCACTATGAGA CCTCAGTCCTTCTATGATGGAAGTCATTCTTGTGCCAGAGGAGTGTGCCATATTCCAATG GCTGAGCCGTTTTGCCCCAAAACGAGAGAGGTTCTTATAGAGACTGCTAAGAAGCTAGGA CTCCGGTGCCACTCAAAGGGGACAATGGTCACAATCGAGGGACCTCGTTTTAGCTCCCGG GCAGAAAGCTTCATGTTCCGCACCTGGGGGGCGGATGTTATCAACATGACCACAGTTCCA GAGGTGGTTCTTGCTAAGGAGGCTGGAATTTGTTACGCAAGTATCGCCATGGCGACAGAT TATGACTGCTGGAAGGAGCACGAGGAAGCAGTTTCGGTGGACCGGGTCTTAAAGACCCTG AAAGAAAACGCTAATAAAGCCAAAAGCTTACTGCTCACTACCATACCTCAGATAGGGTCC ACAGAATGGTCAGAAACCCTCCATAACCTGAAGAATATGGCCCAGTTTTCTGTTTTATTA CCAAGACATTAA Clone variation with respect to NM_002451.3 166 g=>a >OriGene 5' read for NM_002451 unedited
ATTTGTATACGACTCACTATAGGCGGCCGCGAATTCGGCACGAGGCCACCGCTCTGTGGC TCGCTTGGTTCCCTTAGTCCCGAGCGCTCGCCCACTGCAGATTCCTTTCCCGTGCAGACA TGGCCTCTGGCACCACCACCACCGCCGTGAAGATTGGAATAATTGGTGGAACAGGCCTGG ATGATCCAGAAATTTTAGAAGGAAGAACTGAAAAATATGTGGATACTCCATTTGGCAAGC CATCTGATGCCTTAATTTTGGGGAAGATAAAAAATGTTGATTGCATCCTCCTTGCAAGGC ATGGAAGGCAGCACACCATCATGCCTTCAAAGGTCAACTACCAGGCGAACATCTGGGCTT TGAAGGAAGAGGGCTGTACACATGTCATAGTGACCACAGCTTGTGGCTCCTTGAGGGAGG AGATTCAGCCCGGCGATATTGTCATTATTGATCAGTTCATTGACAGGACCACTATGAGAC CTCAGTCCTTCTATGATGGAAGTCATTCTTGTGCCAGAGGAGTGTGCCATATTCCAATGG CTGAGCCGTTTTGCCCCAAAACGAGAGAGGTTCTTATAGAGACTGCTAAGAAGCTAGGAC TCCGGTGCCACTCAAAGGGGACAATGGTCACAATCGAGGGACCTCGTTTTAGCTCCCGGG CAGAAAGCTTCATGTTCCGCACCTGGGGGGCGGATGTTATCAACATGACCACAGTTCCAG AAGTGGTTCTTGCTAAGGACGCTGTAATTTGTTACGCAAGTATCGCCATGCCGACAGATT ATGACTGCTGGCAAGAGCACCATGAAGCAGTTTCCGTGCACCCGGTCCTTAAGACCTTGA AGCAAACGCTATAAAGCCAAAAGCTACTGCTCATACCATACCTCAGATAGGTCCCAGAAT GGTCANAACCCTCCATACCTGGAGATATGCCCAGCTTTTGTCTTATACCAGCAATAAATG ACATGCTGCCCAGG >OriGene 3' read for NM_002451 unedited
CGCAATCTATAGTCGAGTTTTTTTTTTTTTTTTTTCTAAATCCACTTTTATTTTTACAAC AACTTTACTATTTGATTATATTCACTGTAGAAAAATGTGAAGACACAGAAAGATTCAAAG AAAATAAAAATTATCCCAGTATCCCTCCCCCAAATACAATAACAAGGTTATATATATTTC TTTCTAGTTTTTTTGTATATTTACATAGCATTTTAAAGCAAAACTAGTACTATAAAATGC TACCATATCCTTTTTTCACTTCATATATAGAGCAACCGTGTCTTTTTAGGACATTGAAAT ATGCAAAAAGGATTTTCAGTTGGCTGATTCACAATCTAATTATAACTAAGACATAATTTA CCTCCAATTGCAAGGGATTCAGATTGTTTCAATTATTTATTATTATAACTATCATTATTA AACACCCTTCTTTATATATAATTCTTTGTATGCATCTCTGATATGGTTTTAAAGAGAAAT TGCTAGATGTAGAGTTCCCAGCACAAAGTACGTCCGTATTTTTAAGTCTTTAGATGCATT TTACCAAATTGCCCTCCAGAAATACTGTACCAATTTACAGTCGCATCAATAAATAACCAA AGAGTCCCATTTCTTCCTCACATTCTTTGGCAGTATAGGAAAGTAAAGATTACCCTCCAC CCTTTATTGTTGCAAATTTATAGGGGGAGAAGAGATTGGCGGGGTTTTTTTTCCCCTTAA ATGAATATTTTTTACCCATGTTACCAGCCATTGGCTTTCTTCTGATTTTGAAGTGGCCAA TCATTCAAGAATCTTTATACACCAATGCATGTTCTTTTACAAAATATCTTTGTAGCCAGG GCTTGAAGCTGATGTTTTTCCATATTTTTCAGTTAACAGAATTCCAATGATGGATTAATG CTCTTTTTTCCGGACACCAGCTTTTATTGCTTGCTAAAAAAAAAGTGGCCTTTTTCAGTT TGAAGTTCTGACTACCG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_002451 |
| Insert Size | 1950 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_002451.3, NP_002442.2 |
| RefSeq Size | 4937 bp |
| RefSeq ORF | 852 bp |
| Locus ID | 4507 |
| UniProt ID | Q13126 |
| Domains | Mtap_PNP |
| Protein Families | Druggable Genome |
| Protein Pathways | Cysteine and methionine metabolism, Metabolic pathways |
| Gene Summary | This gene encodes an enzyme that plays a major role in polyamine metabolism and is important for the salvage of both adenine and methionine. The encoded enzyme is deficient in many cancers because this gene and the tumor suppressor p16 gene are co-deleted. Multiple alternatively spliced transcript variants have been described for this gene, but their full-length natures remain unknown. [provided by RefSeq, Jul 2008] |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Role for human arylamine N-acetyltransferase 1 in the methionine salvage pathway
,Witham, KL;Minchin, RF;Butcher, NJ;,
Biochem. Pharmacol.
,PubMed ID 27865712
[MTAP]
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|
Nicotinamide Riboside and Nicotinic Acid Riboside Salvage in Fungi and Mammals: QUANTITATIVE BASIS FOR Urh1 AND PURINE NUCLEOSIDE PHOSPHORYLASE FUNCTION IN NAD+ METABOLISM
,Peter Belenky, Kathryn C. Christensen, Francesca Gazzaniga, Alexandre A. Pletnev, and Charles Brenner,
J. Biol. Chem., Jan 2009; 284: 158 - 164.
[MTAP]
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Other Versions
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| RC206024 | MTAP (Myc-DDK-tagged)-Human methylthioadenosine phosphorylase (MTAP) |
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| RC206024L1 | Lenti ORF clone of Human methylthioadenosine phosphorylase (MTAP), Myc-DDK-tagged |
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| RC206024L2 | Lenti ORF clone of Human methylthioadenosine phosphorylase (MTAP), mGFP tagged |
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| RC206024L3 | Lenti ORF clone of Human methylthioadenosine phosphorylase (MTAP), Myc-DDK-tagged |
CNY 4,800.00 |
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| RC206024L4 | Lenti ORF clone of Human methylthioadenosine phosphorylase (MTAP), mGFP tagged |
CNY 4,800.00 |
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| RG206024 | MTAP (tGFP-tagged) - Human methylthioadenosine phosphorylase (MTAP) |
CNY 4,370.00 |
