CCK4 (PTK7) (NM_002821) Human Untagged Clone
CAT#: SC118391
PTK7 (untagged)-Human PTK7 protein tyrosine kinase 7 (PTK7), transcript variant PTK7-1
CNY 7,456.00
Cited in 3 publications. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | CCK-4; CCK4 |
Vector | pCMV6-XL4 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene ORF sequence for NM_002821 edited
ATGGGAGCTGCGCGGGGATCCCCGGCCAGACCCCGCCGGTTGCCTCTGCTCAGCGTCCTG CTGCTGCCGCTGCTGGGCGGTACCCAGACAGCCATTGTCTTCATCAAGCAGCCGTCCTCC CAGGATGCACTGCAGGGGCGCCGGGCGCTGCTTCGCTGTGAGGTTGAGGCTCCGGGCCCG GTACATGTGTACTGGCTGCTCGATGGGGCCCCTGTCCAGGACACGGAGCGGCGTTTCGCC CAGGGCAGCAGCCTGAGCTTTGCAGCTGTGGACCGGCTGCAGGACTCTGGCACCTTCCAG TGTGTGGCTCGGGATGATGTCACTGGAGAAGAAGCCCGCAGTGCCAACGCCTCCTTCAAC ATCAAATGGATTGAGGCAGGTCCTGTGGTCCTGAAGCATCCAGCCTCGGAAGCTGAGATC CAGCCACAGACCCAGGTCACACTTCGTTGCCACATTGATGGGCACCCTCGGCCCACCTAC CAATGGTTCCGAGATGGGACCCCCCTTTCTGATGGTCAGAGCAACCACACAGTCAGCAGC AAGGAGCGGAACCTGACGCTCCGGCCAGCTGGTCCTGAGCATAGTGGGCTGTATTCCTGC TGCGCCCACAGTGCTTTTGGCCAGGCTTGCAGCAGCCAGAACTTCACCTTGAGCATTGCT GATGAAAGCTTTGCCAGGGTGGTGCTGGCACCCCAGGACGTGGTAGTAGCGAGGTATGAG GAGGCCATGTTCCATTGCCAGTTCTCAGCCCAGCCACCCCCGAGCCTGCAGTGGCTCTTT GAGGATGAGACTCCCATCACTAACCGCAGTCGCCCCCCACACCTCCGCAGAGCCACAGTG TTTGCCAACGGGTCTCTGCTGCTGACCCAGGTCCGGCCACGCAATGCAGGGATCTACCGC TGCATTGGCCAGGGGCAGAGGGGCCCACCCATCATCCTGGAAGCCACACTTCACCTAGCA GAGATTGAAGACATGCCGCTATTTGAGCCACGGGTGTTTACAGCTGGCAGCGAGGAGCGT GTGACCTGCCTTCCCCCCAAGGGTCTGCCAGAGCCCAGCGTGTGGTGGGAGCACGCGGGA GTCCGGCTGCCCACCCATGGCAGGGTCTACCAGAAGGGCCACGAGCTGGTGTTGGCCAAT ATTGCTGAAAGTGATGCTGGTGTCTACACCTGCCACGCGGCCAACCTGGCTGGTCAGCGG AGACAGGATGTCAACATCACTGTGGCCACTGTGCCCTCCTGGCTGAAGAAGCCCCAAGAC AGCCAGCTGGAGGAGGGCAAACCCGGCTACTTGGATTGCCTGACCCAGGCCACACCAAAA CCTACAGTTGTCTGGTACAGAAACCAGATGCTCATCTCAGAGGACTCACGGTTCGAGGTC TTCAAGAATGGGACCTTGCGCATCAACAGCGTGGAGGTGTATGATGGGACATGGTACCGT TGTATGAGCAGCACCCCAGCCGGCAGCATCGAGGCGCAAGCCCGTGTCCAAGTGCTGGAA AAGCTCAAGTTCACACCACCACCCCAGCCACAGCAGTGCATGGAGTTTGACAAGGAGGCC ACGGTGCCCTGTTCAGCCACAGGCCGAGAGAAGCCCACTATTAAGTGGGAACGGGCAGAT GGGAGCAGCCTCCCAGAGTGGGTGACAGACAACGCTGGGACCCTGCATTTTGCCCGGGTG ACTCGAGATGACGCTGGCAACTACACTTGCATTGCCTCCAACGGGCCGCAGGGCCAGATT CGTGCCCATGTCCAGCTCACTGTGGCAGTTTTTATCACCTTCAAAGTGGAACCAGAGCGT ACGACTGTGTACCAGGGCCACACAGCCCTACTGCAGTGCGAGGCCCAGGGGGACCCCAAG CCGCTGATTCAGTGGAAAGGCAAGGACCGCATCCTGGACCCCACCAAGCTGGGACCCAGG ATGCACATCTTCCAGAATGGCTCCCTGGTGATCCATGACGTGGCCCCTGAGGACTCAGGC CGCTACACCTGCATTGCAGGCAACAGCTGCAACATCAAGCACACGGAGGCCCCCCTCTAT GTCGTGGACAAGCCTGTGCCGGAGGAGTCGGAGGGCCCTGGCAGCCCTCCCCCCTACAAG ATGATCCAGACCATTGGGTTGTCGGTGGGTGCCGCTGTGGCCTACATCATTGCCGTGCTG GGCCTCATGTTCTACTGCAAGAAGCGCTGCAAAGCCAAGCGGCTGCAGAAGCAGCCCGAG GGCGAGGAGCCAGAGATGGAATGCCTCAACGGTGGGCCTTTGCAGAACGGGCAGCCCTCA GCAGAGATCCAAGAAGAAGTGGCCTTGACCAGCTTGGGCTCCGGCCCCGCGGCCACCAAC AAACGCCACAGCACAAGTGATAAGATGCACTTCCCACGGTCTAGCCTGCAGCCCATCACC ACGCTGGGGAAGAGTGAGTTTGGGGAGGTGTTCCTGGCAAAGGCTCAGGGCTTGGAGGAG GGAGTGGCAGAGACCCTGGTACTTGTGAAGAGCCTGCAGAGCAAGGATGAGCAGCAGCAG CTGGACTTCCGGAGGGAGTTGGAGATGTTTGGGAAGCTGAACCACGCCAACGTGGTGCGG CTCCTGGGGCTGTGCCGGGAGGCTGAGCCCCACTACATGGTGCTGGAATATGTGGATCTG GGAGACCTCAAGCAGTTCCTGAGGATTTCCAAGAGCAAGGATGAAAAATTGAAGTCACAG CCCCTCAGCACCAAGCAGAAGGTGGCCCTATGCACCCAGGTAGCCCTGGGCATGGAGCAC CTGTCCAACAACCGCTTTGTGCATAAGGACTTGGCTGCGCGTAACTGCCTGGTCAGTGCC CAGAGACAAGTGAAGGTGTCTGCCCTGGGCCTCAGCAAGGATGTGTACAACAGTGAGTAC TACCACTTCCGCCAGGCCTGGGTGCCGCTGCGCTGGATGTCCCCCGAGGCCATCCTGGAG GGTGACTTCTCTACCAAGTCTGATGTCTGGGCCTTCGGTGTGCTGATGTGGGAAGTGTTT ACACATGGAGAGATGCCCCATGGTGGGCAGGCAGATGATGAAGTACTGGCAGATTTGCAG GCTGGGAAGGCTAGACTTCCTCAGCCCGAGGGCTGCCCTTCCAAACTCTATCGGCTGATG CAGCGCTGCTGGGCCCTCAGCCCCAAGGACCGGCCCTCCTTCAGTGAGATTGCCAGCGCC CTGGGAGACAGCACCGTGGACAGCAAGCCGTGA >OriGene 5' read for NM_002821 unedited
NNNNGGGGCNAANNNNCTTTCTCCACNNNNGGTTCAGAATTGTAAACGATTATATAGGCG GCCGCGNAATTCGCACGAGCCGCGCTCCGGTGCGCTCCGCCTCCTGTGCCCGCCGCGGAG CGCAGTCTGCGCGCCCGCCGTGCGCCCTCAGCTCCTTTTCCTGAGCCCGCCGCGATGGGA GCTGCGCGGGGATCCCCGGCCAGACCCCGCCGGTTGCCTCTGCTCAGCGTCCTGCTGCTG CCGCTGCTGGGCGGTACCCAGACAGCCATTGTCTTCATCAAGCAGCCGTCCTCCCAGGAT GCACTGCAGGGGCGCCGGGCGCTGCTTCGCTGTGAGGTTGAGGCTCCGGGCCCGGTACAT GTGTACTGGCTGCTCGATGGGGCCCCTGTCCAGGACACGGAGCGGCGTTTCGCCCAGGGC AGCAGCCTGAGCTTTGCAGCTGTGGACCGGCTGCAGGACTCTGGCACCTTCCAGTGTGTG GCTCGGGATGATGTCACTGGAGAAGAAGCCCGCAGTGCCAACGCCTCCTTCAACATCAAA TGGATTGAGGCAGGTCCTGTGGTCCTGAAGCATCCAGCCTCGGAAGCTGAGATCCAGCCA CAGACCCAGGTCACACTTCGTTGCCACATTGATGGGCACCCTCGGCCCACCTACCAATGG TTCCGAGATGGGACCCCCCTTTCTGATGGTCAGAGGCACCACACAGTCAGCAGCAAAGAG CGGAACCTGACGCTNCGGCCAGCTGGTCCTGAGCATAGTGGGGCTGTATTCCTGCTGCGC CCACAGTGCCTTTGGCCAGGCTTGCAGCAGCCAGAACTTCACCTTGAGCATTGCTGATGA AAGCTTGCCAGGGTGGTGCTGGCACCCCAGACCTGTTANTACCGAGGTATGAGGAGGCCT GTTCCATTGGCAGTTTTCAGCCCAGCCACCCCCGACCTGCATGGGCTCTTTTGGGATGAC ACTCCATCATTAACCGAG >OriGene 3' read for NM_002821 unedited
NNAAAATACTGTGGACCGCGAGCCGCAATCTAGGATCGAGTTTTTTTCTTTTTTTTTTAA AAAAGCTTATTTATTGAGAGCAGCGAGTGTAAAAACAAAAACAAAAACAAAAAAACAAAA CAAACAAAAAACGACAACAATAAAAGTGTGGGGTAAGGATGGCCCACCCTCCTCATCTCC AGGGCCCACCCCTACCTCCCATGCCCACCCACCCCACGCTGTATTTACATATAAAAGCCG CCCGTGGTGCATACAAAAAGGGCGGTTTATATAGTGTCAAAAGCTCCTGAAAACTCCTTC ATCTGCCAGGCACTTAGGATGAGGAAAGGAGAAAAGGGTGGGGAAGACGTGGGTCTGGGT CAGTGTGCACAAGCCCAGAGTGGGGAGGACTCACTTGCTGTGTCCTCTATAATCCTGGTC TAGACCCCCAAGTGGGACCAGTGGGCCAAGAGACTCATTAACCCTGTGTGCCCAGAACTT GAGAATATTAAGGAACATCCCACAAACCCAGCTCATCCCAAGCCTAGCCCTCCCCAGGCA AAGTTGGCAGATGAGTGGCAGAGTTGGACCCGGTCAAGGGGAGAAGTTGAAGGCCAGAAA TTGGGGTTACCTGTGGCACCCACACTGTCCCTGATAGAGGAAGAGGTGGCAGGGGAAACT GCCCAGCTCAAAGCCCTAGTCGCCCAGTTTGGGTCCAAGTCAGCCTCCCAAAGGATGAGG GTGAGGAAGAGGAGGAAAGGCCAGGCCCTGCTCAGACCTCAGCAATGCCTGTTGCACTAG GGCAGGGGCCTCNAGGCCCAGGAGGACAGGGATCTTGCCCATCATGCTGTGAGCTTCCCT CTAGAGATGTCCTCCCCTGCCCAGGCCATCCTGAGCGGGCTCCCTCCTCACGGCTTGCTG TCCACGGTGCTGTCTCCCAGGCGCTGG |
Restriction Sites | NotI-NotI |
ACCN | NM_002821 |
Insert Size | 3213 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_002821.3, NP_002812.2 |
RefSeq Size | 4273 bp |
RefSeq ORF | 3213 bp |
Locus ID | 5754 |
UniProt ID | Q13308 |
Domains | pkinase, TyrKc, S_TKc, ig, IGc2, IG |
Protein Families | Druggable Genome, Protein Kinase, Transmembrane |
Gene Summary | This gene encodes a member of the receptor protein tyrosine kinase family of proteins that transduce extracellular signals across the cell membrane. The encoded protein lacks detectable catalytic tyrosine kinase activity, is involved in the Wnt signaling pathway and plays a role in multiple cellular processes including polarity and adhesion. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012] Transcript Variant: This variant (PTK7-1) represents the longest transcript and encodes isoform a. |
Citations (3)
The use of this cDNA Clones has been cited in the following citations: |
---|
MiR‐503 pleiotropically regulates epithelial‐mesenchymal transition and targets PTK7 to control lung cancer metastasis
,null,
Cancer Medicine
,PubMed ID 37212485
[PTK7]
|
Downstream signaling and genome-wide regulatory effects of PTK7 pseudokinase and its proteolytic fragments in cancer cells
,Golubkov, VS;Strongin, AY;,
Cell Commun. Signal
,PubMed ID 24618420
[PTK7]
|
Human CD4+ T cell recent thymic emigrants are identified by protein tyrosine kinase 7 and have reduced immune function
,Christopher J. Haines, Thierry D. Giffon, Li-Sheng Lu, Xiaowei Lu, Marc Tessier-Lavigne, Douglas T. Ross, and David B. Lewis,
. Exp. Med., Feb 2009; 206: 275 - 285.
[PTK7]
|
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Other Versions
SKU | Description | Size | Price |
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RC209690 | PTK7 (Myc-DDK-tagged)-Human PTK7 protein tyrosine kinase 7 (PTK7), transcript variant PTK7-1 |
CNY 10,640.00 |
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RC209690L1 | Lenti-ORF clone of PTK7 (Myc-DDK-tagged)-Human PTK7 protein tyrosine kinase 7 (PTK7), transcript variant PTK7-1 |
CNY 13,576.00 |
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RC209690L2 | Lenti-ORF clone of PTK7 (mGFP-tagged)-Human PTK7 protein tyrosine kinase 7 (PTK7), transcript variant PTK7-1 |
CNY 12,540.00 |
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RC209690L3 | Lenti-ORF clone of PTK7 (Myc-DDK-tagged)-Human PTK7 protein tyrosine kinase 7 (PTK7), transcript variant PTK7-1 |
CNY 12,540.00 |
|
RC209690L4 | Lenti-ORF clone of PTK7 (mGFP-tagged)-Human PTK7 protein tyrosine kinase 7 (PTK7), transcript variant PTK7-1 |
CNY 13,576.00 |
|
RC600063 | PTK7 (DDK-His-tagged)-Extra Cellular Domain Clone of Homo sapiens PTK7 protein tyrosine kinase 7, transcript variant PTK7-1, Signal peptide (1-30) plus EC domain (31-704) |
CNY 5,160.00 |
|
RG209690 | PTK7 (tGFP-tagged) - Human PTK7 protein tyrosine kinase 7 (PTK7), transcript variant PTK7-1 |
CNY 12,776.00 |