SDHD (NM_003002) Human Untagged Clone
CAT#: SC118276
SDHD (untagged)-Human succinate dehydrogenase complex, subunit D, integral membrane protein (SDHD), nuclear gene encoding mitochondrial protein
CNY 1,200.00
CNY 2,950.00
Product images
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | CBT1; CII-4; CWS3; cybS; MC2DN3; PGL; PGL1; QPs3; SDH4 |
Vector | pCMV6-XL5 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene ORF sequence for NM_003002 edited
ATGGCGGTTCTCTGGAGGCTGAGTGCCGTTTGCGGTGCCCTAGGAGGCCGAGCTCTGTTG CTTCGAACTCCAGTGGTCAGACCTGCTCATATCTCAGCATTTCTTCAGGACCGACCTATC CCAGAATGGTGTGGAGTGCAGCACATACACTTGTCACCGAGCCACCATTCTGGCTCCAAG GCTGCATCTCTCCACTGGACTAGCGAGAGGGTTGTCAGTGTTTTGCTCCTGGGTCTGCTT CCGGCTGCTTATTTGAATCCTTGCTCTGCGATGGACTATTCCCTGGCTGCAGCCCTCACT CTTCATGGTCACTGGGGCCTTGGACAAGTTGTTACTGACTATGTTCATGGGGATGCCTTG CAGAAAGCTGCCAAGGCAGGGCTTTTGGCACTTTCAGCTTTAACCTTTGCTGGGCTTTGC TATTTCAACTATCACGATGTGGGCATCTGCAAAGCTGTTGCCATGCTGTGGAAGCTCTGA >OriGene 5' read for NM_003002 unedited
TGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCAGGAACGAGATGGCG GTTCTCTGGAGGCTGAGTGCCGTTTGCGGTGCCCTAGGAGGCCGAGCTCTGTTGCTTCGA ACTCCAGTGGTCAGACCTGCTCATATCTCAGCATTTCTTCAGGACCGACCTATCCCAGAA TGGTGTGGAGTGCAGCACATACACTTGTCACCGAGCCACCATTCTGGCTCCAAGGCTGCA TCTCTCCACTGGACTAGCGAGAGGGTTGTCAGTGTTTTGCTCCTGGGTCTGCTTCCGGCT GCTTATTTGAATCCTTGCTCTGCGATGGACTATTCCCTGGCTGCAGCCCTCACTCTTCAT GGTCACTGGGGCCTTGGACAAGTTGTTACTGACTATGTTCATGGGGATGCCTTGCAGAAA GCTGCCAAGGCAGGGCTTTTGGCACTTTCAGCTTTAACCTTTGCTGGGCTTTGCTATTTC AACTATCACGATGTGGGCATCTGCAAAGCTGTTGCCATGCTGTGGAAGCTCTGACCTTTT TGACTTCATACTTTGAAGAATTGATGTATGCCTCTTTGCCTCTGCTTTGTCATGCCATTA AGCTCACAATAAGGAAGAAATAACAGATAAGTCCATTGGTGGACAGCCTTCTTCTCTTAA TCACAAGATTATTTTCAGAATTTAATCTTTGAGGANNAGGTTTGAGAGGATTATATCTAA GTTGTGAGACTGANGTCTATATTCTGGTGAGTTAATGGGGGTGCCTCCCAGCTTCTTATA GACTCACAGTATACTAACATGAATATCAGCTTTTGCCTTTCAATTATCAATCTCTTAAGA GATCCCACTTTTTACGATAGNATTGATCAACTTCCTATTGCCTTGGGATAATGACA >OriGene 3' read for NM_003002 unedited
GCCGCAATCNATAGTCGAGTTTTTTCTTTTTTTTTTTCTTTTTTTTTTTTTTTTTTTTTT TTTTTTTTTTTTTTTTAAAAAAAAAACATTTTATTTAAAAAAATTTTTTTCATAAAATAC ATTTTCACATTAAAAATTCCCATTGGGCGAAAATAACAATTTATTACTTATAGTTTTATA TTTGGGGACAGATTGTTTTAAAACATTTTAAATACATTGGGGAATTAAATCTCAATTTAC AGGGGGGAGTATTTTGATACATCTACGGGGAAACTTGCCCTTAAATGGAACTTTTGTTTA TTCAAAACCCCTCCAAGCGTTTTTTCCTAGGATTTAAAAATTTATAATTTGAGCTTTCAG CCTTTCCTAATTTTAAAATTTCCCTACTATATGTAACCATCAGTAGGGGGTCTCTCCCGG CTACAGAGGGAAGTTTTCCAAAATTAAACCTTGGTTCATTTTCCGCAAAGCTTTTTTTCA TGAATTAACAGTCTTCCCCTTTGCCCATTATTCCCAAGGGAAATCGGGAAGTTTGATCCT TTCTAACCGCATTAAAGCGGGTTCTCTTTTAAAAGATTGACAAATTGAAAGGCAAAAGCT GATCTTTCCTGTTTACTCATCACGGGGAGTTTCATCAAAAGCCGGGCGGCCTCCCCTCTA CTTCCCAAATATAAAACTTGTTCCCCCCTCAAATATATTCTTCTAAACCCTCGCCACAGA TACAACCTAAAACACCTTGGACAACAAAAAAGGTTCCCCCCGGGGCTTTTGTTTATTCCC CATGGGACCTTTGGCTTGCCAACCCGGCCATGGGTTTCTTTCTCTTTCATGTGACCCATT CGGTAACCCTTCCACCTGGCAACTTTGCCAGCCCACTTGGGTGTGTACCGTAATCTTCAG GCCACTTTAAGTCCAACCCCGTTTGGATCTTCCAGGTCCCCCGCCAAT |
Restriction Sites | NotI-NotI |
ACCN | NM_003002 |
Insert Size | 1320 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_003002.1, NP_002993.1 |
RefSeq Size | 1313 bp |
RefSeq ORF | 480 bp |
Locus ID | 6392 |
UniProt ID | O14521 |
Protein Pathways | Alzheimer's disease, Citrate cycle (TCA cycle), Huntington's disease, Metabolic pathways, Oxidative phosphorylation, Parkinson's disease |
Gene Summary | This gene encodes a member of complex II of the respiratory chain, which is responsible for the oxidation of succinate. The encoded protein is one of two integral membrane proteins anchoring the complex to the matrix side of the mitochondrial inner membrane. Mutations in this gene are associated with the formation of tumors, including hereditary paraganglioma. Transmission of disease occurs almost exclusively through the paternal allele, suggesting that this locus may be maternally imprinted. There are pseudogenes for this gene on chromosomes 1, 2, 3, 7, and 18. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2013] Transcript Variant: This variant (1) encodes the longest isoform (a). |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC203269 | SDHD (Myc-DDK-tagged)-Human succinate dehydrogenase complex, subunit D, integral membrane protein (SDHD), nuclear gene encoding mitochondrial protein |
CNY 1,200.00 |
|
RC203269L1 | Lenti ORF clone of Human succinate dehydrogenase complex, subunit D, integral membrane protein (SDHD), nuclear gene encoding mitochondrial protein, Myc-DDK-tagged |
CNY 3,600.00 |
|
RC203269L2 | Lenti ORF clone of Human succinate dehydrogenase complex, subunit D, integral membrane protein (SDHD), nuclear gene encoding mitochondrial protein, mGFP tagged |
CNY 5,890.00 |
|
RC203269L3 | Lenti ORF clone of Human succinate dehydrogenase complex, subunit D, integral membrane protein (SDHD), nuclear gene encoding mitochondrial protein, Myc-DDK-tagged |
CNY 5,890.00 |
|
RC203269L4 | Lenti ORF clone of Human succinate dehydrogenase complex, subunit D, integral membrane protein (SDHD), nuclear gene encoding mitochondrial protein, mGFP tagged |
CNY 5,890.00 |
|
RG203269 | SDHD (tGFP-tagged) - Human succinate dehydrogenase complex, subunit D, integral membrane protein (SDHD), nuclear gene encoding mitochondrial protein |
CNY 2,800.00 |