United States
Germany
Japan
United Kingdom
China
STAT6 (NM_003153) Human Untagged Clone
CAT＃: SC118195
STAT6 (untagged)-Human signal transducer and activator of transcription 6, interleukin-4 induced (STAT6), transcript variant 2
CNY 6,208.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | D12S1644; IL-4-STAT; STAT6B; STAT6C |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_003153 edited
ATGTCTCTGTGGGGTCTGGTCTCCAAGATGCCCCCAGAAAAAGTGCAGCGGCTCTATGTC GACTTTCCCCAACACCTGCGGCATCTTCTGGGTGACTGGCTGGAGAGCCAGCCCTGGGAG TTCCTGGTCGGCTCCGACGCCTTCTGCTGCAACTTGGCTAGTGCCCTACTTTCAGACACT GTCCAGCACCTTCAGGCCTCGGTGGGAGAGCAGGGGGAGGGGAGCACCATCTTGCAACAC ATCAGCACCCTTGAGAGCATATATCAGAGGGACCCCCTGAAGCTGGTGGCCACTTTCAGA CAAATACTTCAAGGAGAGAAAAAAGCTGTTATGGAACAGTTCCGCCACTTGCCAATGCCT TTCCACTGGAAGCAGGAAGAACTCAAGTTTAAGACAGGCTTGCGGAGGCTGCAGCACCGA GTAGGGGAGATCCACCTTCTCCGAGAAGCCCTGCAGAAGGGGGCTGAGGCTGGCCAAGTG TCTCTGCACAGCTTGATAGAAACTCCTGCTAATGGGACTGGGCCAAGTGAGGCCCTGGCC ATGCTACTGCAGGAGACCACTGGAGAGCTAGAGGCAGCCAAAGCCCTAGTGCTGAAGAGG ATCCAGATTTGGAAACGGCAGCAGCAGCTGGCAGGGAATGGCGCACCGTTTGAGGAGAGC CTGGCCCCACTCCAGGAGAGGTGTGAAAGCCTGGTGGACATTTATTCCCAGCTACAGCAG GAGGTAGGGGCGGCTGGTGGGGAGCTTGAGCCCAAGACCCGGGCATCGCTGACTGGCCGG CTGGATGAAGTCCTGAGAACCCTCGTCACCAGTTGCTTCCTGGTGGAGAAGCAGCCCCCC CAGGTACTGAAGACTCAGACCAAGTTCCAGGCTGGAGTTCGATTCCTGTTGGGCTTGAGG TTCCTGGGGGCCCCAGCCAAGCCTCCGCTGGTCAGGGCCGACATGGTGACAGAGAAGCAG GCGCGGGAGCTGAGTGTGCCTCAGGGTCCTGGGGCTGGAGCAGAAAGCACTGGAGAAATC ATCAACAACACTGTGCCCTTGGAGAACAGCATTCCTGGGAACTGCTGCTCTGCCCTGTTC AAGAACCTGCTTCTCAAGAAGATCAAGCGGTGTGAGCGGAAGGGCACTGAGTCTGTCACA GAGGAGAAGTGCGCTGTGCTCTTCTCTGCCAGCTTCACACTTGGCCCCGGCAAACTCCCC ATCCAGCTCCAGGCCCTGTCTCTGCCCCTGGTGGTCATCGTCCATGGCAACCAAGACAAC AATGCCAAAGCCACTATCCTGTGGGACAATGCCTTCTCTGAGATGGACCGCGTGCCCTTT GTGGTGGCTGAGCGGGTGCCCTGGGAGAAGATGTGTGAAACTCTGAACCTGAAGTTCATG GCTGAGGTGGGGACCAACCGGGGGCTGCTCCCAGAGCACTTCCTCTTCCTGGCCCAGAAG ATCTTCAATGACAACAGCCTCAGTATGGAGGCCTTCCAGCACCGTTCTGTGTCCTGGTCG CAGTTCAACAAGGAGATCCTGCTGGGCCGTGGCTTCACCTTTTGGCAGTGGTTTGATGGT GTCCTGGACCTCACCAAACGCTGTCTCCGGAGCTACTGGTCTGACCGGCTGATCATTGGC TTCATCAGCAAACAGTACGTTACTAGCTTTCTTCTCAATGAGCCCGACGGAACCTTTCTC CTCCGCTTCAGCGACTCAGAGATTGGGGGCATCACCATTGCCCATGTCATCCGGGGCCAG GATGGCTCTCCACAGATAGAGAACATCCAGCCATTCTCTGCCAAAGACCTGTCCATTCGC TCACTGGGGGACCGAATCCGGGATCTTGCTCAGCTCAAAAATCTCTATCCCAAGAAGCCC AAGGATGAGGCTTTCCGGAGCCACTACAAGCCTGAACAGATGGGTAAGGATGGCAGGGGT TATGTCCCAGCTACCATCAAGATGACCGTGGAAAGGGACCAACCACTTCCTACCCCAGAG CTCCAGATGCCTACCATGGTGCCTTCTTATGACCTTGGAATGGCCCCTGATTCCTCCATG AGCATGCAGCTTGGCCCAGATATGGTGCCCCAGGTGTACCCACCACACTCTCACTCCATC CCCCCGTATCAAGGCCTCTCCCCAGAAGAATCAGTCAACGTGTTGTCAGCCTTCCAGGAG CCTCACCTGCAGATGCCCCCCAGCCTGGGCCAGATGAGCCTGCCCTTTGACCAGCCTCAC CCCCAGGGCCTGCTGCCGTGCCAGCCTCAGGAGCATGCTGTGTCCAGCCCTGACCCCCTG CTCTGCTCAGATGTGACCATGGTGGAAGACAGCTGCCTGAGCCAGCCAGTGACAGCGTTT CCTCAGGGCACTTGGATTGGTGAAGACATATTCCCTCCTCTGCTGCCTCCCACTGAACAG GACCTCACTAAGCTTCTCCTGGAGGGGCAAGGGGAGTCGGGGGGAGGGTCCTTGGGGGCA CAGCCCCTCCTGCAGCCCTCCCACTATGGGCAATCTGGGATCTCAATGTCCCACATGGAC CTAAGGGCCAACCCCAGTTGGTGA >OriGene 5' read for NM_003153 unedited
GTTCAGATTTGTATACGACTCACTATAGGCGGCCGACGAATTCGCACGAGGTGAAGAGGG AGGACGGGAGAGGAGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTATGTATGTGTGTGCTT TATCTTATTTTTCTTTTTGGTGGTGGTGGTGGAAGGGGGGAGGTGCTAGCAGGGCCAGCC TTGAACTCGCTGGACAGAGCTACAGACCTATGGGGCCTGGAAGTGCCCGCTGAGAAAGGG AGAAGACAGCAGAGGGGTTGCCGAGGCAACCTCCAAGTCCCAGATCATGTCTCTGTGGGG TCTGGTCTCCAAGATGCCCCCAGAAAAAGTGCAGCGGCTCTATGTCGACTTTCCCCAACA CCTGCGGCATCTTCTGGGTGACTGGCTGGAGAGCCAGCCCTGGGAGTTCCTGGTCGGCTC CGACGCCTTCTGCTGCAACTTGGCTAGTGCCCTACTTTCAGACACTGTCCAGCACCTTCA GGCCTCGGTGGGAGAGCAGGGGGAGGGGAGCACCATCTTGCAACACATCAGCACCCTTGA GAGCATATATCAGAGGGACCCCCTGAAGCTGGTGGCCACTTTCAGACAAATACTTCAAGG AGAGAAAAAAGCTGTTATGGAACAGTTCCGCCACTTGCCAATGCCTTTCCACTGGAAGCA GGAAGAACTCAAGTTTAAGACAGGCTTGCGGAGGCTGCAGCACCGAGTAGGGGAGATCCA CCTTCTCCGAGAAGCCCTGCAGAAGGAGGCTGANGCTGGCCAAGTGTCTCTGCACAGCTT GATAGAAACTCCTGCNTATGGGACTGGGCCAAGTGAGGCCCTGGCCATGCTACTGCANGA GACCACTGGAGAGCTAGAGGCAGCCAAAGCCCTAGTGCTNGAGAGGATCCAAATTNGAAA ACGCAGCANCAGCTGGCAGGGAATGCG >OriGene 3' read for NM_003153 unedited
GCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTGTGGGCATGCAACTAAGGTGCCA GCTATATATTTAACATATCCTAGGTACATACACGTTCACACAGCTATACACGAAGAATCT CAGCCCTTGTACTTTTGCATAGTCTCATACACGTATCAAAAGCCTCCACCTGGCTAACAG GAATTTGGGGCTTTGGGAGATTTTTTAATCAGGGCAAAACCTGTACTAGTAACCACATGT CCAGACTCCTCCTATGCTCCCACCCAGGGTCCCTTGAGCTGCTTCCCATTCCCCTAGGGC TGAGACCCAATATCCTCTATCCCTGGCCTCTAGTGTAAATGTGTCTGTATGTTCCTGCCT ATCCGTCCTAAGCCCTGGGTCAGAATGGGCGGAGAAGCCTTCCATGCCCTAACCTGTGCT CTTACCCAGCCCCCCTCCTGCTCAGCCCCATCACCCTCAGAGAGCTCTGTATGTGTGTGT GCGTGCGTGTGCGCGCTGCAAGTGCAGGCATGTTGGGGCGTGTCTCAAAGCCTGAACTTC CCTTCCANTCANTGCTGGAAGGAAGTGGGCAGGGGAATGATTCAAAGGAAGGAGTGGATT GGCTCCACCCACTGTGCATTCTCCTGTTAGTCTTTTCCTCCTGACCCACGAGTANGTGGG GATAGGAAGGCACCCTTNCCATCTGCTGCTTGGCAAGGCATGACCCAGTGTCCATAGCAG GTCTGTGGGGGTAAGANAAAAACTGGTTCTTTGGGTTCTCCTTCAGCTGGGATCAACAAC TGGGGTTGGCCCTTAGGTCCATGTGGGAAATTGGAATCCCAAATTGCCCCTATTGGAAAG GCTGCAGGAGGGGCTTTGCCCCCCAGGAACCTTCCCCCGAATCCCTTGGGCCCCCAAGAG AACTTATGGAGGCCCGTTCCATGGAAGCGCGCAAGGAGGAATTGTTTTCACAACCAACGC CTTAGGAACCCGGACTGCTTGGTCAGCACTGTCTT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_003153 |
| Insert Size | 3460 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_003153.3, NP_003144.3 |
| RefSeq Size | 3993 bp |
| RefSeq ORF | 2544 bp |
| Locus ID | 6778 |
| UniProt ID | P42226 |
| Domains | SH2, STAT |
| Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Stem cell relevant signaling - DSL/Notch pathway, Stem cell relevant signaling - JAK/STAT signaling pathway, Transcription Factors |
| Protein Pathways | Jak-STAT signaling pathway |
| Gene Summary | The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010] Transcript Variant: This variant (2) uses an alternate splice site in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein (isoform 1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Insulin Receptor Substrate-1/2 Mediates IL-4-Induced Migration of Human Air-way Epithelial Cells
,Steven R. White, Linda D. Martin, Mark K. Abe, Bertha A. Marroquin, Randi Stern, and Xiaoying Fu,
Am J Physiol Lung Cell Mol Physiol, May 2009; 10.1152/ajplung.90453.2008.
[STAT6]
|
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC210065 | STAT6 (Myc-DDK-tagged)-Human signal transducer and activator of transcription 6, interleukin-4 induced (STAT6), transcript variant 2 |
CNY 9,304.00 |
|
| RC210065L1 | Lenti ORF clone of Human signal transducer and activator of transcription 6, interleukin-4 induced (STAT6), transcript variant 2, Myc-DDK-tagged |
CNY 11,704.00 |
|
| RC210065L2 | Lenti ORF clone of Human signal transducer and activator of transcription 6, interleukin-4 induced (STAT6), transcript variant 2, mGFP tagged |
CNY 11,704.00 |
|
| RC210065L3 | Lenti ORF clone of Human signal transducer and activator of transcription 6, interleukin-4 induced (STAT6), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC210065L4 | Lenti ORF clone of Human signal transducer and activator of transcription 6, interleukin-4 induced (STAT6), transcript variant 2, mGFP tagged |
CNY 11,704.00 |
|
| RG210065 | STAT6 (tGFP-tagged) - Human signal transducer and activator of transcription 6, interleukin-4 induced (STAT6), transcript variant 2 |
CNY 10,904.00 |
