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Serum Response Factor (SRF) (NM_003131) Human Untagged Clone
CAT＃: SC118177
SRF (untagged)-Human serum response factor (c-fos serum response element-binding transcription factor) (SRF)
CNY 2,950.00
| Cited in 3 publications. |
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热销推荐Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | MCM1 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_003131, the custom clone sequence may differ by one or more nucleotides
ATGTTACCGACCCAAGCTGGGGCCGCGGCGGCTCTGGGCCGGGGCTCGGCCCTGGGGGGCAGCCTGAACC GGACCCCGACGGGGCGGCCGGGCGGCGGCGGCGGGACACGCGGGGCTAACGGGGGCCGGGTCCCCGGGAA TGGCGCGGGGCTCGGGCCCGGCCGCCTGGAGCGGGAGGCTGCGGCAGCGGCGGCAACCACCCCGGCGCCC ACCGCGGGGGCCCTCTACAGCGGCAGCGAGGGCGACTCGGAGTCGGGCGAGGAGGAGGAGCTGGGCGCCG AGCGGCGCGGCCTGAAGCGGAGCCTGAGCGAGATGGAGATCGGTATGGTGGTCGGTGGGCCCGAGGCGTC GGCAGCGGCCACCGGGGGCTACGGGCCGGTGAGCGGCGCGGTGAGCGGGGCCAAGCCGGGTAAGAAGACC CGGGGCCGCGTGAAGATCAAGATGGAGTTCATCGACAACAAGCTGCGGCGCTACACGACCTTCAGCAAGA GGAAGACGGGCATCATGAAGAAGGCCTATGAGCTGTCCACGCTGACAGGGACACAGGTGCTGTTGCTGGT GGCCAGTGAGACAGGCCATGTGTATACCTTTGCCACCCGAAAACTGCAGCCCATGATCACCAGTGAGACC GGCAAGGCACTGATTCAGACCTGCCTCAACTCGCCAGACTCTCCACCCCGTTCAGACCCCACAACAGACC AGAGAATGAGTGCCACTGGCTTTGAAGAGACAGATCTCACCTACCAGGTGTCGGAGTCTGACAGCAGTGG GGAGACCAAGGACACACTGAAGCCGGCGTTCACAGTCACCAACCTGCCGGGTACAACCTCCACCATCCAA ACAGCACCTAGCACCTCTACCACCATGCAAGTCAGCAGCGGCCCCTCCTTTCCCATCACCAACTACCTGG CACCAGTGTCTGCTAGTGTCAGCCCCAGTGCTGTCAGCAGTGCCAATGGGACTGTGCTGAAGAGTACAGG CAGCGGCCCTGTCTCCTCTGGGGGCCTTATGCAGCTGCCTACCAGCTTCACCCTCATGCCTGGTGGGGCA GTGGCCCAGCAGGTCCCAGTGCAGGCCATTCAAGTGCACCAGGCCCCACAGCAAGCGTCTCCCTCCCGTG ACAGCAGCACAGACCTCACGCAGACCTCCTCCAGCGGGACAGTGACGCTGCCCGCCACCATCATGACGTC ATCCGTGCCCACAACTGTGGGTGGCCACATGATGTACCCTAGCCCGCATGCGGTGATGTATGCCCCCACC TCGGGCCTGGGTGATGGCAGCCTCACCGTGCTGAATGCCTTCTCCCAGGCACCATCCACCATGCAGGTGT CACACAGCCAGGTCCAGGAGCCAGGTGGCGTCCCCCAGGTGTTCCTGACAGCATCATCTGGGACAGTGCA GATCCCTGTTTCAGCAGTTCAGCTCCACCAGATGGCTGTGATAGGGCAGCAGGCCGGGAGCAGCAGCAAC CTCACCGAGCTACAGGTGGTGAACCTGGACACCGCCCACAGCACCAAGAGTGAATGA >OriGene 5' read for NM_003131 unedited
GTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGCCACAGGGGCAGGAAA GTGAGGGCCCAGGTCGGCCCGGGCGTGCAGGGGCCCCGGGTTCGCAGCGGCGGCCGCGGC AGCGATAGCGGCACTAGCAGCAGCGGGAGTGCCGGGTTGAGCCGGGAAGCCGATGGCGGC GGCTGCGGCGGCTCCGATTCCTCGCTGACTGCCCGTCCGCCCTCCTGCATCGAGCGCCAT GTTACCGACCCAAGCTGGGGCCGCGGCGGCTCTGGGCCGGGGCTCGGCCCTGGGGGGCAG CCTGAACCGGACCCCGACGGGGCGGCCGGGCGGCGGCGGCGGGACACGCGGGGCTAACGG GGGCCGGGTCCCCGGGAATGGCGCGGGGCTCGGGCCCGGCCGCCTGGAGCGGGAGGCTGC GGCAGCGGCGGCAACCACCCCGGCGCCCACCGCGGGGGCCCTCTACAGCGGCAGCGAGGG CGACTCGGAGTCGGGCGAGGAGGAGGAGCTGGGCGCCGAGCGGCGCGGCCTGAAGCGGAG CCTGAGCGAGATGGAGATCGGTATGGTGGTCGGTGGGCCCGAGGCGTCGGCAGCGGCCAC CGGGGGCTACGGGCCGGTGAGCGGCGCGGTGAGCGGTGCCAATCCGGGTAAGAAGACCCG GGGCCGCGTGAAGATCAAGATGGAGTTCATCGACACCAGCTGCGGCGCTACACGACCTTC AGCAAGAAGAAGACGGGCATCATGAAAGAAGCCTATGAGCTGTCCACGCTGACAGGGACA CAGGTTGCTGTTGCTGGTGGCCAGTGAGACAGCCATGTGTATACCTTTTGCCACCCGAAA CTGCAGCCCATGATCACCATGAGACCGGCAAGCACTGATTCAAACCTGCCTCATCTGCAG ACTCTCCACCCGTTAGACCCCACACAGACANAGGATGATCGCCCTGCT >OriGene 3' read for NM_003131 unedited
TTATAGCATTTGGTTTTCACTTTTCGTCTCCTCAAATAAAAAGTTCAAAATCAACTTTAA GTAAAGCAGCTGGGAGGAGAGGGGGGAAGACAAGGGGGAGAAGGGAACGCTGGTGGTTCC CTCCAACCCAGGAGCCCCTGGAGGTCCAAGGGGAGCGGCAAGGCAGGGCAGGCGGCCCCA GGAACCTGCCCAGTGCACAGGCCCAGCTACTCAGGAGCTGAAGGGGGAGAGGACAGCAGT GTGAGGAAGAAGCCCCCATCTCCCCAGCTGGCCCCCTGAGGGGCAGAGCCAGGGCTCTTT TGACCCAGCCTGTGACAGACACAGGGCTGACCTGGGGTCAGCAAGGAGGCTGGCAAGAGG GCCCCAACTGCTTCCTCAGAGGAGGACACGGTGCCCAGCCCCACAGAATGCCTGTGTGTG GGGAGGTGGGGCACGGTCCCATTGGGTAAGCTAATACTCATGGCAAACATCGAGCCAAGC TGGCGAGGGGGTCCCATGAAGGAGGACAGCCCCTTCAGCAACAGAAATGTGATGTGGGGC GGGAACAAAGGGAGGCTGATGGACGACCGTTGCGAGCTTGCATGCCCTTTCCTTTGCCTG ACTCATAGGCCTCACCCTCGGCCGCCCTTCCTCTTCCCCCCTCCTTCTTCCTTTCTCCCT CCCCCTTCCTCCCCCCCTCACCTCCCCCTTTTTTCTCCCCTCTCTTCTCTCCCAGATATT TTTTTTCCCCCTCTCCTCCCCCCCTCCTTTCCCCCTTCCCCCCTTTCTTTTTTATTCGTC ACATTCCCCGCCCCGTTTCCGTCTTTTCCCCCTCCCATTTCCCCCCCCTTCTCTTTACGT TCCTTCTTTTTTTTCCCTTTCCTCCCTTCCCTCCTTCTTTCTCCCTTTCTTTTTTCCTTT TTTCCCCCTCCTTCTTCCTCTTCCCCCTCCTCTTCTCTTCCCTATTTTCTCCCCCCCCAT TCTTTTCTTTCTTCCTCCCCCTCCTTATCTTCCATCCTCGATTCTTTCTCTTT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_003131 |
| Insert Size | 2740 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_003131.2, NP_003122.1 |
| RefSeq Size | 4343 bp |
| RefSeq ORF | 1527 bp |
| Locus ID | 6722 |
| UniProt ID | P11831 |
| Domains | MADS |
| Protein Families | Druggable Genome, Transcription Factors |
| Protein Pathways | MAPK signaling pathway |
| Gene Summary | This gene encodes a ubiquitous nuclear protein that stimulates both cell proliferation and differentiation. It is a member of the MADS (MCM1, Agamous, Deficiens, and SRF) box superfamily of transcription factors. This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate-early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation. This gene is the downstream target of many pathways; for example, the mitogen-activated protein kinase pathway (MAPK) that acts through the ternary complex factors (TCFs). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2014] Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). |
Citations (3)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Novel mutations of the SRF gene in Chinese sporadic conotruncal heart defect patients
,Mengmeng, X;Yuejuan, X;Sun, C;Yanan, L;Fen, L;Kun, S;,
BMC Med. Genet.
,PubMed ID 32380971
[SRF]
|
|
Reduction of miR-132-3p contributes to gastric cancer proliferation by targeting MUC13
,null,
Molecular Medicine Reports
,PubMed ID 28339011
[SRF]
|
|
Smooth Muscle Expression of Lipoma Preferred Partner Is Mediated by an Alternative Intronic Promoter That Is Regulated by Serum Response Factor/Myocardin
,Marleen M.R. Petit, Henrik Lindskog, Erik Larsson, Per Wasteson, Elisabeth Athley, Silke Breuer, Meike Angstenberger, David Hertfelder, Erney Mattsson, Alfred Nordheim, Sven Nelander, and Per Lindahl,
Circ. Res., Jul 2008; 103: 61 - 69.
[SRF]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC208596 | SRF (Myc-DDK-tagged)-Human serum response factor (c-fos serum response element-binding transcription factor) (SRF) |
CNY 3,784.00 |
|
| RC208596L1 | Lenti ORF clone of Human serum response factor (c-fos serum response element-binding transcription factor) (SRF), Myc-DDK-tagged |
CNY 6,184.00 |
|
| RC208596L2 | Lenti ORF clone of Human serum response factor (c-fos serum response element-binding transcription factor) (SRF), mGFP tagged |
CNY 6,460.00 |
|
| RC208596L3 | Lenti ORF clone of Human serum response factor (c-fos serum response element-binding transcription factor) (SRF), Myc-DDK-tagged |
CNY 6,460.00 |
|
| RC208596L4 | Lenti ORF clone of Human serum response factor (c-fos serum response element-binding transcription factor) (SRF), mGFP tagged |
CNY 6,460.00 |
|
| RG208596 | SRF (tGFP-tagged) - Human serum response factor (c-fos serum response element-binding transcription factor) (SRF) |
CNY 5,040.00 |
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