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TLR1 (NM_003263) Human Untagged Clone
CAT＃: SC118088
TLR1 (untagged)-Human toll-like receptor 1 (TLR1)
CNY 5,768.00
CNY 7,220.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CD281; rsc786; TIL; TIL. LPRS5 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_003263, the custom clone sequence may differ by one or more nucleotides
ATGACTAGCATCTTCCATTTTGCCATTATCTTCATGTTAATACTTCAGATCAGAATACAATTATCTGAAG AAAGTGAATTTTTAGTTGATAGGTCAAAAAACGGTCTCATCCACGTTCCTAAAGACCTATCCCAGAAAAC AACAATCTTAAATATATCGCAAAATTATATATCTGAGCTTTGGACTTCTGACATCTTATCACTGTCAAAA CTGAGGATTTTGATAATTTCTCATAATAGAATCCAGTATCTTGATATCAGTGTTTTCAAATTCAACCAGG AATTGGAATACTTGGATTTGTCCCACAACAAGTTGGTGAAGATTTCTTGCCACCCTACTGTGAACCTCAA GCACTTGGACCTGTCATTTAATGCATTTGATGCCCTGCCTATATGCAAAGAGTTTGGCAATATGTCTCAA CTAAAATTTCTGGGGTTGAGCACCACACACTTAGAAAAATCTAGTGTGCTGCCAATTGCTCATTTGAATA TCAGCAAGGTCTTGCTGGTCTTAGGAGAGACTTATGGGGAAAAAGAAGACCCTGAGGGCCTTCAAGACTT TAACACTGAGAGTCTGCACATTGTGTTCCCCACAAACAAAGAATTCCATTTTATTTTGGATGTGTCAGTC AAGACTGTAGCAAATCTGGAACTATCTAATATCAAATGTGTGCTAGAAGATAACAAATGTTCTTACTTCC TAAGTATTCTGGCGAAACTTCAAACAAATCCAAAGTTATCAAATCTTACCTTAAACAACATTGAAACAAC TTGGAATTCTTTCATTAGGATCCTCCAGCTGGTTTGGCATACAACTGTATGGTATTTCTCAATTTCAAAC GTGAAGCTACAGGGTCAGCTGGACTTCAGAGATTTTGATTATTCTGGCACTTCCTTGAAGGCCTTGTCTA TACACCAAGTTGTCAGCGATGTGTTCGGTTTTCCGCAAAGTTATATCTATGAAATCTTTTCGAATATGAA CATCAAAAATTTCACAGTGTCTGGTACACGCATGGTCCACATGCTTTGCCCATCCAAAATTAGCCCGTTC CTGCATTTGGATTTTTCCAATAATCTCTTAACAGACACGGTTTTTGAAAATTGTGGGCACCTTACTGAGT TGGAGACACTTATTTTACAAATGAATCAATTAAAAGAACTTTCAAAAATAGCTGAAATGACTACACAGAT GAAGTCTCTGCAACAATTGGATATTAGCCAGAATTCTGTAAGCTATGATGAAAAGAAAGGAGACTGTTCT TGGACTAAAAGTTTATTAAGTTTAAATATGTCTTCAAATATACTTACTGACACTATTTTCAGATGTTTAC CTCCCAGGATCAAGGTACTTGATCTTCACAGCAATAAAATAAAGAGCATTCCTAAACAAGTCGTAAAACT GGAAGCTTTGCAAGAACTCAATGTTGCTTTCAATTCTTTAACTGACCTTCCTGGATGTGGCAGCTTTAGC AGCCTTTCTGTATTGATCATTGATCACAATTCAGTTTCCCACCCATCGGCTGATTTCTTCCAGAGCTGCC AGAAGATGAGGTCAATAAAAGCAGGGGACAATCCATTCCAATGTACCTGTGAGCTAGGAGAATTTGTCAA AAATATAGACCAAGTATCAAGTGAAGTGTTAGAGGGCTGGCCTGATTCTTATAAGTGTGACTACCCGGAA AGTTATAGAGGAACCCTACTAAAGGACTTTCACATGTCTGAATTATCCTGCAACATAACTCTGCTGATCG TCACCATCGTTGCCACCATGCTGGTGTTGGCTGTGACTGTGACCTCCCTCTGCAGCTACTTGGATCTGCC CTGGTATCTCAGGATGGTGTGCCAGTGGACCCAGACCCGGCGCAGGGCCAGGAACATACCCTTAGAAGAA CTCCAAAGAAATCTCCAGTTTCATGCATTTATTTCATATAGTGGGCACGATTCTTTCTGGGTGAAGAATG AATTATTGCCAAACCTAGAGAAAGAAGGTATGCAGATTTGCCTTCATGAGAGAAACTTTGTTCCTGGCAA GAGCATTGTGGAAAATATCATCACCTGCATTGAGAAGAGTTACAAGTCCATCTTTGTTTTGTCTCCCAAC TTTGTCCAGAGTGAATGGTGCCATTATGAACTCTACTTTGCCCATCACAATCTCTTTCATGAAGGATCTA ATAGCTTAATCCTGATCTTGCTGGAACCCATTCCGCAGTACTCCATTCCTAGCAGTTATCACAAGCTCAA AAGTCTCATGGCCAGGAGGACTTATTTGGAATGGCCCAAGGAAAAGAGCAAACGTGGCCTTTTTTGGGCT AACTTAAGGGCAGCCATTAATATTAAGCTGACAGAGCAAGCAAAGAAATAG >OriGene 5' read for NM_003263 unedited
TCACAATTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGGAACAGA CAAGCAGGTTGTCTTGGGTCTTCATGAACACTAATAGGGGTACCAGGCCCTCTTCCTCGT TAGAAGAAATCAGGATAACAAAGGCATATTGGGCACCCCTACAAAAGGAATCTGTATCTG TATCAAGATGATCTGAAGAACAGCTTCTACCTTTAGGAATGTCTAGTGTTCCAAAATGAC TAGCATCTTCCATTTTGCCATTATCTTCATGTTAATACTTCAGATCAGAATACAATTATC TGAAGAAAGTGAATTTTTAGTTGATAGGTCAAAAAACGGTCTCATCCACGTTCCTAAAGA CCTATCCCAGAAAACAACAATCTTAAATATATCGCAAAATTATATATCTGAGCTTTGGAC TTCTGACATCTTATCACTGTCAAAACTGAGGATTTTGATAATTTCTCATAATAGAATCCA GTATCTTGATATCAGTGTTTTCAAATTCAACCAGGAATTGGAATACTTGGATTTGTCCCA CAACAAGTTGGTGAAGATTTCTTGCCACCCTACTGTGAACCTCAAGCACTTGGACCTGTC ATTTAATGCATTTGATGCCCTGCCTATATGCAAAGAGTTTGGCAATATGTCTCAACTAAN NATTCTGGNGTTGAGCACCACACACTTTAGAAAATCTAGTGTGCTGCCAATTGCTCATTT GAATATCAGNCAAGTCTTGCTGGTCTTANGAGAGAACTATGGNGAANAAAGAAGACCCTN GAGGCCCTTCAAGAACTTAACACTTGAGAGTCTGCACATTGTGTTCCCCCACCAACAAAG AATTCCATCTTATTTTGGATGTGTCAGTCAAGACTGTAGCAAATCTGGAACCTATCTATT ATCAAAGTGTGCTAGAAGAATACAAATGGTCCTACTTCCCTAGTATTCTGGCGAN >OriGene 3' read for NM_003263 unedited
CGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTACATTTCATTAATTTTTAA TACCACATATAAATGGTGAACTGCGACCCGAAGGTATATATTTTTACCTACATCATACAC TCACAATTGTGTTTACATCTATGCTGATGCAAAATAAAGTCATTGTTGGAACTTCCAAAA GCAGCAATATCAACAGGAGGAATATTTTTCACTTGATGTGTAATCTATTTCTTTGCTTGC TCTGTCAGCTTAATATTAATGGCTGCCCTTAAGTTAGCCCAAAAAAGGCCACGTTTGCTC TTTTCCTTGGGCCATTCCAAATAAGTCCTCCTGGCCATGAGACTTTTGAGCTTGTGATAA CTGCTAGGAATGGAGTACTGAGGAATGGGTTCCAGCAAGATCAGGATTAAGCTATTAGAT CCTTCATGAAAGAGATTGTGATGGGCAAAGTAGAGTTCATAATGGCACCATTCACTCTGG ACAAAGTTGGGAGACAAAACAAAGATGGACTTGTAACTCTTCTCAATGCAGGTGATGATA TTTTCCACAATGCTCTTGCCAGGAACAAAGTTTCTCTCATGAAGGCAAATCTGCATACCT TCTTTCTCTAGGTTTGGCAATAATTCATTCTTCACCCAGAAAGAATCGTGCCCACTATAT GAAATAAATGCATGAAACTGGAGATTTCTTTGTAGTTCTTCTAAGGGTATGTTCCTGGCC CCTGCGCCGGGTTTGGGTCCACTGGCCACACCATCCTGAGAATCCCAGGCCATATTCCAG TACCTGTCCAAGGAGGGCCCATTCACACCCCCCCCCTCATGGGGGCAACAATGGCGACAA TCACAAGACTTTTGTCGCAGATAATCCAACTTGGAAAACCCTCTAAAGGGTCCCTTTAAA CTTCCGGGTGTCACCCTATAAAATAGGCCACCCTCAAAACTAATTGAACCTGGCTTTATT TTACAN |
| Restriction Sites | NotI-NotI |
| ACCN | NM_003263 |
| Insert Size | 2820 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_003263.3, NP_003254.2 |
| RefSeq Size | 2867 bp |
| RefSeq ORF | 2361 bp |
| Locus ID | 7096 |
| UniProt ID | Q15399 |
| Domains | TIR, LRRCT, LRR, LRR_TYP |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Toll-like receptor signaling pathway |
| Gene Summary | The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is ubiquitously expressed, and at higher levels than other TLR genes. Different length transcripts presumably resulting from use of alternative polyadenylation site, and/or from alternative splicing, have been noted for this gene. [provided by RefSeq, Jul 2008] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Pancreatic adenocarcinoma upregulated factor promotes metastasis by regulating TLR/CXCR4 activation
,H D Park, Y Lee, Y K Oh, J G Jung, Y W Park, K Myung, K-H Kim, S S Koh, D-S Lim,
Oncogene (30 August 2010) doi:10.1038/onc.2010.401 Original Article
[TLR1]
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