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TGF beta 3 (TGFB3) (NM_003239) Human Untagged Clone
CAT＃: SC118071
TGFB3 (untagged)-Human transforming growth factor, beta 3 (TGFB3)
CNY 3,656.00
CNY 6,650.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ARVD; ARVD1; LDS5; RNHF; TGF-beta3 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_003239 edited
GAATTCGGCACGAGGGCTTCTTCGTCCTCAGGGTTGCCAGCGCTTCCTGGAAGTCCTGAA GCTCTCGCAGTGCAGTGAGTTCATGCACCTTCTTGCCAAGCCTCAGTCTTTGGGATCTGG GGAGGCCGCCTGGTTTTCCTCCCTCCTTCTGCACGTCTGCTGGGGTCTCTTCCTCTCCAG GCCTTGCCGTCCCCCTGGCCTCTCTTCCCAGCTCACACATGAAGATGCACTTGCAAAGGG CTCTGGTGGTCCTGGCCCTGCTGAACTTTGCCACGGTCAGCCTCTCTCTGTCCACTTGCA CCACCTTGGACTTCGGCCACATCAAGAAGAAGAGGGTGGAAGCCATTAGGGGACAGATCT TGAGCAAGCTCAGGCTCACCAGCCCCCCTGAGCCAACGGTGATGACCCACGTCCCCTATC AGGTCCTGGCCCTTTACAACAGCACCCGGGAGCTGCTGGAGGAGATGCATGGGGAGAGGG AGGAAGGCTGCACCCAGGAAAACACCGAGTCGGAATACTATGCCAAAGAAATCCATAAAT TCGACATGATCCAGGGGCTGGCGGAGCACAACGAACTGGCTGTCTGTCCTAAAGGAATTA CCTCCAAGGTTTTCCGCTTCAATGTGTCCTCAGTGGAGAAAAATAGAACCAACCTATTCC GAGCAGAATTCCGGGTCTTGCGGGTGCCCAACCCCAGCTCTAAGCGGAATGAGCAGAGGA TCGAGCTCTTCCAGATCCTTCGGCCAGATGAGCACATTGCCAAACAGCGCTATATCGGTG GCAAGAATCTGCCCACACGGGGCACTGCCGAGTGGCTGTCCTTTGATGTCACTGACACTG TGCGTGAGTGGCTGTTGAGAAGAGAGTCCAACTTAGGTCTAGAAATCAGCATTCACTGTC CATGTCACACCTTTCAGCCCAATGGAGATATCCTGGAAAACATTCACGAGGTGATGGAAA TCAAATTCAAAGGCGTGGACAATGAGGATGACCATGGCCGTGGAGATCTGGGGCGCCTCA AGAAGCAGAAGGATCACCACAACCCTCATCTAATCCTCATGATGATTCCCCCACACCGGC TCGACAACCCGGGCCAGGGGGGTCAGAGGAAGAAGCGGGCTTTGGACACCAATTACTGCT TCCGCAACTTGGAGGAGAACTGCTGTGTGCGCCCCCTCTACATTGACTTCCGACAGGATC TGGGCTGGAAGTGGGTCCATGAACCTAAGGGCTACTATGCCAACTTCTGCTCAGGCCCTT GCCCATACCTCCGCAGTGCAGACACAACCCACAGCACGGTGCTGGGACTGTACAACACTC TGAACCCTGAAGCATCTGCCTCGCCTTGCTGCGTGCCCCAGGACCTGGAGCCCCTGACCA TCCTGTACTATGTTGGGAGGACCCCCAAAGTGGAGCAGCTCTCCAACATGGTGGTGAAGT CTTGTAAATGTAGCTGAGACCCCACGTGCGACAGAGAGAGGGGAGAGAGAACCACCACTG CCTGACTGCCCGCTCCTCGGGAAACACACAAGCAACAAACCTCACTGAGAGGCCTGGAGC CCACAACCTTCGGCTCCGGGCAAATGGCTGAGATGGAGGTTTCCTTTTGGAACATTTCTT TCTTGCTGGCTCTGAGAATCACGGTGGTAAAGAAAGTGTGGGTTTGGTTAGAGGAAGGCT GAACTCTTCAGAACACACAGACTTTCTGTGACGCAGACAGAGGGGATGGGGATAGAGGAA AGGGATGGTAAGTTGAGATGTTGTGTGGCAATGGGATTTGGGCTACCCTAAAGGGAGAAG GAAGGGCAGAGAATGGCTGGGTCAGGGCCAGACTGGAAGACACTTCAGATCTGAGGTTGG ATTTGCTCATTGCTGTACCACATCTGCTCTAGGGAATCTGGATTATGTTATACAAGGCAA GCATTTTTTTTTTTTTTTTAAAGACAGGTTACGAAGACAAAGTCCCAGAATTGTATCTCA TACTGTCTGGGATTAAGGGCAAATCTATTACTTTTGCAAACTGTCCTCTACATCAATTAA CATCGTGGGTCACTACAGGGAGAAAATCCAGGTCATGCAGTTCCTGGCCCATCAACTGTA TTGGGCCTTTTGGATATGCTGAACGCAGAAGAAAGGGTGGAAATCAACCCTCTCCTGTCT GCCCTCTGGGTCCCTCCTCTCACCTCTCCCTCGATCATATTTCCCCTTGGACACTTGGTT AGACGCCTTCCAGGTCAGGATGCACATTTCTGGATTGTGGTTCCATGCAGCCTTGGGGCA TTATGGGTTCTTCCCCCACTTCCCCTCCAAGACCCTGTGTTCATTTGGTGTTCCTGGAAG CAGGTGCTACAACATGTGAGGCATTCGGGGAAGCTGCACATGTGCCACACAGTGACTTGG CCCCAGACGCATAGACTGAGGTATAAAGACAAGTATGAATATTACTCTCAAAATCTTTGT ATAAATAAATATTTTTGGGGCATCCTGGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAACTCGAC >OriGene 5' read for NM_003239 unedited
GTGTACATTTGTATACGACTCACTATAGGCGGCCGCGAATCGGCACGAGGGCTTCTTCGT CCTCGGGTTGCCAGCGCTTCCTGGAAGTCCTGAAGCTCTCGCAGTGCAGTGAGTTCATGC ACCTTCTTGCCAAGCCTCAGTCTTTGGGATCTGGGGAGGCCGCCTGGTTTTCCTCCCTCC TTCTGCACGTCTGCTGGGGTCTCTTCCTCTCCAGGCCTTGCCGTCCCCCTGGCCTCTCTT CCCAGCTCACACATGAAGATGCACTTGCAAAGGGCTCTGGTGGTCCTGGCCCTGCTGAAC TTTGCCACGGTCAGCCTCTCTCTGTCCACTTGCACCACCTTGGACTTCGGCCACATCAAG AAGAAGAGGGTGGAAGCCATTAGGGGACAGATCTTGAGCAAGCTCAGGCTCACCAGCCCC CCTGAGCCAACGGTGATGACCCACGTCCCCTATCAGGTCCTGGCCCTTTACAACAGCACC CGGGAGCTGCTGGAGGAGATGCATGGGGAGAGGGAGGAAGGCTGCACCCAGGAAAACACC GAGTCGGAATACTATGCCAAAGAAATCCATAAATTCGACATGATCCAGGGGCTGGCGGAG CACAACGAACTGGCTGTCTGTCCTAAAGGAATTACCTCCAAGGTTTTCCGCTTCAATGTG TCCTCAGTGGAGAAAAATAGAACCAACCTATTCCGAGCAGAATTCCGGGTCTTGCGGGTG CCCAACCCCAGCTCTAAGCGGAATGAGCAGAAGATCGAGCTCTTCCGATCCCTTCGCCAG ATGAGCACATTGCCAAACAGCGCTATATCGGTGGCCAGAATCTGCCCACCCGGGCACTGC CGAGTGGCTGTCCTTTTGAGTCACTGACACTGTGCGTGAGTGCCTGTTGAAAAAAGAGTC CACTTAAGTCTAGAAATCANCT >OriGene 3' read for NM_003239 unedited
GGGGTGGTTTTTCTTTTTACCAACCCAACCCACACCCTTTTTGGCCCCAAATATATTTTT ATACAAATATTTGTGCGTAATATTCATACTTGTCTTTATACCTCAGTCTATGCGTCTGGG GCCAAGTCACTGTGTGGCACATGTGCAGCTTCCCCGATGCCTCCATGTTGTAGCACCTGC TTCCAGGAACACCAAATGAACACAGGGTCCTTGGAGGGGAAGTGGGGGAAGAACCCATAA TGCCCCAAGGCTGCATGGAACCACAATCCAGAAATGTGCATCCTGACCTGGAAGGCGTCT AACCAAGTGTCCAAGGGGAAATATGATCGAGGGAGAGGTGAGAGGAGGGACCCATAGGGC AGACAGGAGAGGGTTGATTTCCACCCTTTCTTCTGCGTTCAGCATATCCAAAAGGCCCAA TACAGTTGATGGGCCAGGAACTGCATGACCTGGATTTTCTCCCTGTAGTGACCCACGATG TTAATTGATGTAGAGGACAGTTTGCAAAAGTAATAGATTTGCCCTTTATCCCACACAGTA TGAGATACAATTCTGGGACTTTGTCTTCGTAACCTGTCTTTAAAAAAAAAAAAAAAAATG CTTGCCCTTGTATAACATAATCCAGATTCCCTAGAGCCAGATGTGGTACAGCAATGAGCA AATCCAACCTCAGATCTGAAGTGTCTTCCACTCTGGGCCCCTGACCAAACCATTTTCTGT CCTTCTCTTTTCCTTTAAGGTAGCCCAAATCCCATTGCCACACAACATCTTAACTTAACC ATCCTTTTCCTTTATCCCCATTCCCCTCTGTCTGCGTCACAAAAAGACTGTGTGGTTCTG AAGAGTTCACACTTCCTCTTAACCAACCCCCAATTTTTTTTTACCACCGTGATTTTTATA GCCTGTAGAAGAAAAATGTTCCAAAGAG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_003239 |
| Insert Size | 2640 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_003239.1, NP_003230.1 |
| RefSeq Size | 2574 bp |
| RefSeq ORF | 1239 bp |
| Locus ID | 7043 |
| UniProt ID | P10600 |
| Domains | TGFb_propeptide, TGF-beta |
| Protein Families | Druggable Genome, Secreted Protein, Transmembrane |
| Protein Pathways | Cell cycle, Chronic myeloid leukemia, Colorectal cancer, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM), MAPK signaling pathway, Pancreatic cancer, Pathways in cancer, Renal cell carcinoma, TGF-beta signaling pathway |
| Gene Summary | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. This protein is involved in embryogenesis and cell differentiation, and may play a role in wound healing. Mutations in this gene are a cause of aortic aneurysms and dissections, as well as familial arrhythmogenic right ventricular dysplasia 1. [provided by RefSeq, Aug 2016] Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1). Both variants 1 and 2 encode the same isoform (1). |
Documents
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| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC214987 | TGFB3 (Myc-DDK-tagged)-Human transforming growth factor, beta 3 (TGFB3) |
CNY 3,656.00 |
|
| RC214987L1 | Lenti ORF clone of Human transforming growth factor, beta 3 (TGFB3), Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC214987L2 | Lenti ORF clone of Human transforming growth factor, beta 3 (TGFB3), mGFP tagged |
CNY 5,890.00 |
|
| RC214987L3 | Lenti ORF clone of Human transforming growth factor, beta 3 (TGFB3), Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC214987L4 | Lenti ORF clone of Human transforming growth factor, beta 3 (TGFB3), mGFP tagged |
CNY 6,056.00 |
|
| RG214987 | TGFB3 (tGFP-tagged) - Human transforming growth factor, beta 3 (TGFB3) |
CNY 5,256.00 |
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