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TRAF3 (NM_003300) Human Untagged Clone
CAT＃: SC118061
TRAF3 (untagged)-Human TNF receptor-associated factor 3 (TRAF3), transcript variant 3
CNY 4,240.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1; RNF118 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_145725 edited
GAATTCGGCACGAGGCCCAGCCGGGACTTTCCAGCCGGCGGCAGCCGCGGCGGCCGCCGG CTCTTCCCCGCCCCCCGCCATGGGGCAGCCCGGGGAGCAGAACGCTGCGGACCGCGGCGG AGGACGCGCCCGGCGCCCCTGAGCCGGCCGAGCGGCGACGGACCGCGAGATGAGGAAAAT GAGGCCCAAAGAAGTGATGCCACTTGGTTAAGGTCCCAGAGCAGGTCAGAATCAGACCTA GGATCAGAAACCTGGCTCCTGGCTCCTGGCTCCCTACTCTTCTAAGGATCGCTGTCCTGA CAGAAGAGAACTCCTCTTTCCTAAAATGGAGTCGAGTAAAAAGATGGACTCTCCTGGCGC GCTGCAGACTAACCCGCCGCTAAAGCTGCACACTGACCGCAGTGCTGGGACGCCAGTTTT TGTCCCTGAACAAGGAGGTTACAAGGAAAAGTTTGTGAAGACCGTGGAGGACAAGTACAA GTGTGAGAAGTGCCACCTGGTGCTGTGCAGCCCGAAGCAGACCGAGTGTGGGCACCGCTT CTGCGAGAGCTGCATGGCGGCCCTGCTGAGCTCTTCAAGTCCAAAATGTACAGCGTGTCA AGAGAGCATCGTTAAAGATAAGGTGTTTAAGGATAATTGCTGCAAGAGAGAAATTCTGGC TCTTCAGATCTATTGTCGGAATGAAAGCAGAGGTTGTGCAGAGCAGTTAACGCTGGGACA TCTGCTGGTGCATTTAAAAAATGATTGCCATTTTGAAGAACTTCCATGTGTGCGTCCTGA CTGCAAAGAAAAGGTCTTGAGGAAAGACCTGCGAGACCACGTGGAGAAGGCGTGTAAATA CCGGGAAGCCACATGCAGCCACTGCAAGAGTCAGGTTCCGATGATCGCGCTGCAGAAACA CGAAGACACCGACTGTCCCTGCGTGGTGGTGTCCTGCCCTCACAAGTGCAGCGTCCAGAC TCTCCTGAGGAGCGAGTTGAGTGCACACTTGTCAGAGTGTGTCAATGCCCCCAGCACCTG TAGTTTTAAGCGCTATGGCTGCGTTTTTCAGGGGACAAACCAGCAGATCAAGGCCCACGA GGCCAGCTCCGCCGTGCAGCACGTCAACCTGCTGAAGGAGTGGAGCAACTCGCTCGAAAA GAAGGTTTCCTTGTTGCAGAATGAAAGTGTAGAAAAAAACAAGAGCATACAAAGTTTGCA CAATCAGATATGTAGCTTTGAAATTGAAATTGAGAGACAAAAGGAAATGCTTCGAAATAA TGAATCCAAAATCCTTCATTTACAGCGAGTGATAGACAGCCAAGCAGAGAAACTGAAGGA GCTTGACAAGGAGATCCGGCCCTTCCGGCAGAACTGGGAGGAAGCAGACAGCATGAAGAG CAGCGTGGAGTCCCTCCAGAACCGCGTGACCGAGCTGGAGAGCGTGGACAAGAGCGCGGG GCAAGTGGCTCGGAACACAGGCCTGCTGGAGTCCCAGCTGAGCCGGCATGACCAGATGCT GAGTGTGCACGACATCCGCCTAGCCGACATGGACCTGCGCTTCCAGGTCCTGGAGACCGC CAGCTACAATGGAGTGCTCATCTGGAAGATTCGCGACTACAAGCGGCGGAAGCAGGAGGC CGTCATGGGGAAGACCCTGTCCCTTTACAGCCAGCCTTTCTACACTGGTTACTTTGGCTA TAAGATGTGTGCCAGGGTCTACCTGAACGGGGACGGGATGGGGAAGGGGACGCACTTGTC GCTGTTTTTTGTCATCATGCGTGGAGAATATGATGCCCTGCTTCCTTGGCCGTTTAAGCA GAAAGTGACACTCATGCTGATGGATCAGGGGTCCTCTCGACGTCATTTGGGAGATGCATT CAAGCCCGACCCCAACAGCAGCAGCTTCAAGAAGCCCACTGGAGAGATGAATATCGCCTC TGGCTGCCCAGTCTTTGTGGCCCAAACTGTTCTAGAAAATGGGACATATATTAAAGATGA TACAATTTTTATTAAAGTCATAGTGGATACTTCGGATCTGCCCGATCCCTGATAAGTAGC TGGGGAGGTGGATTTAGCAGAAGGCAACTCCTCTGGGGGATTTGAACCGGTCTGTCTTCA CTGAGGTCCTCGCGCTCAGAAAAGGACCTTGTGAGACGGAGGAAGCGGCAGAAGGCGGAC GCGTGCCGGCGGGAGGAGCCACGCGTGAGCACACCTGACACGTTTTATAATAGACTAGCC ACACTTCACTCTGAAGAATTATTTATCCTTCAACAAGATAAATATTGCTGTCAGAGAAGG TTTTCATTTTCATTTTTAAAGATCTAGTTAATTAAGGTGGAAAACATATATGCTAAACAA AAGAAACATGATTTTTCTTCCTTAAACTTGAACACCAAAAAAACACACACACACACACAC GTGGGGATAGCTGGACATGTCAGCATGTTAAGTAAAAGGAGAATTTATGAAATAGTAATG CAATTCTGATATCTTCTTTCTAAAATTCAAGAGTGCAATTTTGTTTCAAATACAGTATAT TGTCTATTTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAACTCGAC >OriGene 5' read for NM_003300 unedited
TGGCAGAAATTTGTATACGACTCACTATAGGGGCGGCCGCGAATTCGCACGAGGCCCAGC CGGGACTTTCCAGCCGGCGGCAGCCGCGGCGGCCGCCGGCTCTTCCCCGCCCCCCGCCAT GGGGCAGCCCGGGGAGCAGAACGCTGCGGACCGCGGCGGAGGACGCGCCCGGCGCCCCTG AGCCGGCCGAGCGGCGACGGACCGCGAGATGAGGAAAATGAGGCCCAAAGAAGTGATGCC ACTTGGTTAAGGTCCCAGAGCAGGTCAGAATCAGACCTAGGATCAGAAACCTGGCTCCTG GCTCCTGGCTCCCTACTCTTCTAAGGATCGCTGTCCTGACAGAAGAGAACTCCTCTTTCC TAAAATGGAGTCGAGTAAAAAGATGGACTCTCCTGGCGCGCTGCAGACTAACCCGCCGCT AAAGCTGCACACTGACCGCAGTGCTGGGACGCCAGTTTTTGTCCCTGAACAAGGAGGTTA CAAGGAAAAGTTTGTGAAGACCGTGGAGGACAAGTACAAGTGTGAGAAGTGCCACCTGGT GCTGTGCAGCCCGAAGCAGACCGAGTGTGGGCACCGCTTCTGCGAGAGCTGCATGGCGGC CCTGCTGAGCTCTTCAAGTCCAAAATGTACAGCGTGTCAAGAGAGCATCGTTAAAGATAA GGTGTTTAAGGATAATTGCTGCAAGAGAGAAATTCTGGCTCTTCAGATCTATTGTCGGAA TGAAAGCAGAGGTTGTGCAGAGCAGTTAACGCTGGGACATCTGCTGGTGCATTTAANAAA TGATTGCCATTNTGAAGAACTCCATGTGTGCGTNCCTGACTGCAAGAAAAGGGTCTGAGG GAAGACCTGCGAGACCACGTGGAGAANGGCGTGNTAATACCGGGAAGCCACATGCAGNCC TGCAGAAGTCAGGNTCCGATGATCGCGCTGCAGAACACGAAGACACGACTGGCCTGCGGT GGTGG >OriGene 3' read for NM_003300 unedited
TTTGGCCGCGGCCGCATTCTANAGNCGAGNTCTTTTTTTTTTTTTTTTTTTTTTTTTTTT TTTTTTAAAAAAAACAATATACTGTATTTGAAAACAAAATTGCACTCTTGAATTTTAACA AAAAAGATACCAAAATTGCATTACTATTTCATAAATTCTCCTTTTACTTAACATGCTGAC ATGTCCAGCTATCCCCACGGGGGTGTGTGTGCGTGCTTTTTTGGGGCTCAAGTTTAAGGA AAAAAAACCATGTTTTTTTTGTTAACCATATATGTTTTCCACCTTAATTAACTAAATCTT TAAAAACGAAAATGAAAACCTTCTCTGACAGAAATATTTATCTTGTTGAAGGATAAATAA TTCTTCAAAGGGAAGGGTGGTTAGCCTATTATAAAACGTGTCAGGTGTGCCTCCGCGGGG TTCCTTCCGCCGGAACGCGCCCGCTTTTTGCCGTTTCCTCCGTCTCACAAGGTCCTTTTC TGAGCGCGAGGACCTCAGGGAAAACAGACCGGCTCAAATCCCCCAGAGGAGTTGCCTTTT GTTAAATCCACCTCCCCAGCTACTTATTAGGGATCGGGCAGATCCGAAGTATCCACTATG ACTTTAATAAAAATTGCATCATCTTTACAATACGTCCCATTTCCTAGAACAGTTTGCCCC ACAAAGCACTGTGCACCCAGAGGCCATATCTATTTCCTCCGCGGGCCTACTTGAACCCGN TGCTGTTGCGGTCGGGCCTGAACCCCCTCCCAAAGACCGCCAAAGCACCCCGACCCATAG CATGAGTGTCACTTCTGCTTAACGGCCAGGAAGAGGCCTTATTTTTCCCCCCGGAGACAA AAACGTGAAGGGGCGCCTCTCCCCATCCGTCCCCGTAAGGCAAACCTGGCCACCTTTATA CCCAGAACCACTGAAAAAGTTGTTTGAAAGGAAGGGTTTCCCAGAGGCCTTCGT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_003300 |
| Insert Size | 2600 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_003300.2, NP_003291.2 |
| RefSeq Size | 2428 bp |
| RefSeq ORF | 1707 bp |
| Locus ID | 7187 |
| UniProt ID | Q13114 |
| Domains | zf-TRAF, RING, MATH |
| Protein Families | Druggable Genome |
| Protein Pathways | Pathways in cancer, RIG-I-like receptor signaling pathway, Small cell lung cancer, Toll-like receptor signaling pathway |
| Gene Summary | The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from, members of the TNF receptor (TNFR) superfamily. This protein participates in the signal transduction of CD40, a TNFR family member important for the activation of the immune response. This protein is found to be a critical component of the lymphotoxin-beta receptor (LTbetaR) signaling complex, which induces NF-kappaB activation and cell death initiated by LTbeta ligation. Epstein-Barr virus encoded latent infection membrane protein-1 (LMP1) can interact with this and several other members of the TRAF family, which may be essential for the oncogenic effects of LMP1. The protein also plays a role in the regulation of antiviral response. Mutations in this are associated with Encephalopathy, acute, infection-induced, herpes-specific 5. [provided by RefSeq, Jul 2020] Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1 and 3 both encode the same isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC218682 | TRAF3 (Myc-DDK-tagged)-Human TNF receptor-associated factor 3 (TRAF3), transcript variant 3 |
CNY 6,344.00 |
|
| RC218682L1 | Lenti ORF clone of Human TNF receptor-associated factor 3 (TRAF3), transcript variant 3, Myc-DDK-tagged |
CNY 8,744.00 |
|
| RC218682L2 | Lenti ORF clone of Human TNF receptor-associated factor 3 (TRAF3), transcript variant 3, mGFP tagged |
CNY 5,890.00 |
|
| RC218682L3 | Lenti ORF clone of Human TNF receptor-associated factor 3 (TRAF3), transcript variant 3, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC218682L4 | Lenti ORF clone of Human TNF receptor-associated factor 3 (TRAF3), transcript variant 3, mGFP tagged |
CNY 5,890.00 |
|
| RG218682 | TRAF3 (tGFP-tagged) - Human TNF receptor-associated factor 3 (TRAF3), transcript variant 3 |
CNY 7,944.00 |
