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UBE2D1 (NM_003338) Human Untagged Clone
CAT＃: SC118046
UBE2D1 (untagged)-Human ubiquitin-conjugating enzyme E2D 1 (UBE2D1), transcript variant 1
CNY 1,200.00
CNY 2,950.00
| Cited in 1 publication. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | E2(17)KB1; SFT; UBC4/5; UBCH5; UBCH5A |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_003338 edited
GAATTCGGCACGAGGCGCGCTCGGGCGCACACGGAGCAGGGACCGGCGCCCGGAGCGAGC CAGGGAGCGGCTAACCGGGGACCCACCGCGCGGAGCCAGCCTAGCTGCCAGCGAGCCCAA CCCGCGACGACCCACGCCCCTGAGCCCCGCAGCCGACCCCTGCCGGCCGGTGTCCCCACC GCCATCCCTGACCCATGGCGCTGAAGAGGATTCAGAAAGAATTGAGTGATCTACAGCGCG ATCCACCTGCTCACTGTTCAGCTGGACCTGTGGGAGATGACTTGTTCCACTGGCAAGCCA CTATTATGGGGCCTCCTGATAGCGCATATCAAGGTGGAGTCTTCTTTCTCACTGTACATT TTCCGACAGATTATCCTTTTAAACCACCAAAGATTGCTTTCACAACAAAAATTTACCATC CAAACATAAACAGTAATGGAAGTATTTGTCTCGATATTCTGAGGTCACAATGGTCACCAG CTCTGACTGTATCAAAAGTTTTATTGTCCATATGTTCTCTACTTTGTGATCCTAATCCAG ATGACCCCTTAGTACCAGATATTGCACAAATCTATAAATCAGACAAAGAAAAATACAACA GACATGCAAGAGAATGGACTCAGAAATATGCAATGTAAAAATCAAAAACATTTTCATATA TACCAGAGTACTGTAAAATCTAGGTTTTTTTCAACATTAGCAGTAAATTGAGCACTGTTT ACTGTTTCATTGTACCATGAAACCATTTGATTTTTACCCATTTTAAATGTGTTTCTGAAG CAAGACAAAACAAACTTCCAAAAATACCCTTAAGACTGTGATGAGAGCATTTATCATTTT GTATGCATTGAGAAAGACATTTATTATGGTTTTTAAGATACTTGGACATCTGCATCTTCA GCTTACAAGATCTACAATGCAGCTGAAAAGCAACCAAATTATTTTTTGCTGAAACTAGAT GTTTTTACATGAGAAATACTGTATGTGTTGTCTAAGATGTCAGTTTTATAAATCTGTATT CAGATTTCATTCTTTGTTAGCTCACTTTATAATTTGTATTTTTTTACTGTATAGACTAAA TATATTCTATTTACATGTATGTCAACTCATTACTTTTTTCCTGTGAACAGTATTGAAAAA CCCCAACGGCTGATAATTAAGTGAATTAACTGTGTCTCCCTTGTCTTAGGATATTCTGTA GATTGATTGCAGATTTCTTAAATCTGAAATGATCTTTACACTGTAATTCTCAGCATACTG ATTATGGAGAAACACTTGTTTTGATTTTGTTATACTTGACTTAACTTTATTGCAATGTGA ATTAATTGCACTGCTAAGTAGGAAGATGTGTAACTTTTATTTGTTGCTATTCACATTTGA ATTTTTXXXXXXXXXXXXXXXXXXXXXXCTCGAC >OriGene 5' read for NM_003338 unedited
ATTTTGTAATACGACTCACTATAGGGGCGGCCGCGAATTCGCACGAGGCGCGCTCGGGCG CACACGGAGCAGGGACCGGCGCCCGGAGCGAGCCAGGGAGCGGCTAACCGGGGACCCACC GCGCGGAGCCAGCCTAGCTGCCAGCGAGCCCAACCCGCGACGACCCACGCCCCTGAGCCC CGCAGCCGACCCCTGCCGGCCGGTGTCCCCACCGCCATCCCTGACCCATGGCGCTGAAGA GGATTCAGAAAGAATTGAGTGATCTACAGCGCGATCCACCTGCTCACTGTTCAGCTGGAC CTGTGGGAGATGACTTGTTCCACTGGCAAGCCACTATTATGGGGCCTCCTGATAGCGCAT ATCAAGGTGGAGTCTTCTTTCTCACTGTACATTTTCCGACAGATTATCCTTTTAAACCAC CAAAGATTGCTTTCACAACAAAAATTTACCATCCAAACATAAACAGTAATGGAAGTATTT GTCTCGATATTCTGAGGTCACAATGGTCACCAGCTCTGACTGTATCAAAAGTTTTATTGT CCATATGTTCTCTACTTTGTGATCCTAATCCAGATGACCCCTTAGTACCAGATATTGCAC AAATCTATAAATCAGACAAAGAAAAATACAACAGACATGCAAGAGAATGGACTCAGAAAT ATGCAATGTAAAAATCAAAAACATTTTCATATATACCAGAGTACTGTAAAATCTAGGTTT TTTTCAACATTAGCAGTAAATTGAGCACTGTTTACTGTTTCATTGTACCATGAAACCATT TGATTNTTACCCATTNTAAATGTGTTTCTGAAGCAAGACANAACANACTTCCAANAATAC CCTTAAGACTGTGATGAGAGCATTTATCATTNTGTATGCATTGAGAAAGAACATTATTAT GGTTTNTAAGATACTGGNACATCTGCATCTTCAGCTTACAAGATCTACAATGCAGCTNGA AAGCAACCNAATNATNNTTTGCTGAAAT >OriGene 3' read for NM_003338 unedited
GCACGCAATCTATAGTCGAGTTTTTTTTTTTTTTTTTTTTCAAGTTTCAAAAACTTTAAT AAAGAAAAAAAAGAAGACACTTCCAAAAATAAATGCCACACAAATGAAAGTTGTTTTTTT TTTTGTTTAAAGGGAAGATATTCAAGAAACAAAACCCTTTACTATCAAAATATACTAAAT ATTTAAATCTAGGGATGTTGAGTGTTCAAATTCAGGGCAAATGTAGCTTATAATAATATA GCTAAGTAAAATTTTTCATGATATGGCTGTTTTAAGACATCATTTTATAGATTTACTTTT TAAGCCTATATTTTCTTAAACATCCATTTCACAATTCATTTAATTATTTTACATTCATTT ATAAAAACACATATTTTCTAACAATAGGTTATTTTGGGCTTTAATAATAATGAACCATGA CAAAATACTCAAGTGATTTAAATGCTTTGCTAATGACTACACCCATCACATATTCTTACA TACTTCTACAGCTACTGCAATAATCAGAAGGGCTACAACTGTTCTTAAAAATGACACTCA CTCAAGGTTGACAAGCATGCTAAACATTAAAGAGATGTATTTTTCCCCAAGTTAAAACAT TAAAACTTTCTAGTTTTCTTTAAAATCTATAAAGATAACCTGCTTATTTAAATCACTTTT CGATGGCAACTTATAAAAACAGAGGGAGGCATAATTNTAGAACTTCCTTTGTAACTTCTA TAGTAAAAAAAAAAANAAGTTTTTCAAATGGTGATGGCATTAAATCCATTTTAGAAATCC TAGATCTTAAATGGTAAGAAATGTNATGTCAATTACATCAAGGTGGGGGGCATTTTAATG AAATAATCTAGTGACTGTGCAGGTCTATAAGACCTTNCTTAGNATGGTGATACTGCCTAT ACTCATTTAGTTCTTTAACAATTATCCTTTANATTAATCCAGAAAACCCAATTCTCTAAT CTCCTTACGCAGGGATCACTTTTNTNCTATGACG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_003338 |
| Insert Size | 2680 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_003338.3, NP_003329.1 |
| RefSeq Size | 2669 bp |
| RefSeq ORF | 444 bp |
| Locus ID | 7321 |
| UniProt ID | P51668 |
| Domains | UBCc |
| Protein Pathways | Ubiquitin mediated proteolysis |
| Gene Summary | The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011] Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
UBE2L3 Polymorphism Amplifies NF-?B Activation and Promotes Plasma Cell Development, Linking Linear Ubiquitination to Multiple Autoimmune Diseases
,Lewis, MJ;Vyse, S;Shields, AM;Boeltz, S;Gordon, PA;Spector, TD;Lehner, PJ;Walczak, H;Vyse, TJ;,
Am. J. Hum. Genet.
,PubMed ID 25640675
[UBE2D1]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC205621 | UBE2D1 (Myc-DDK-tagged)-Human ubiquitin-conjugating enzyme E2D 1 (UBE2D1), transcript variant 1 |
CNY 1,200.00 |
|
| RC205621L1 | Lenti ORF clone of Human ubiquitin-conjugating enzyme E2D 1 (UBE2D1), transcript variant 1, Myc-DDK-tagged |
CNY 3,600.00 |
|
| RC205621L2 | Lenti ORF clone of Human ubiquitin-conjugating enzyme E2D 1 (UBE2D1), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RC205621L3 | Lenti ORF clone of Human ubiquitin-conjugating enzyme E2D 1 (UBE2D1), transcript variant 1, Myc-DDK-tagged |
CNY 3,600.00 |
|
| RC205621L4 | Lenti ORF clone of Human ubiquitin-conjugating enzyme E2D 1 (UBE2D1), transcript variant 1, mGFP tagged |
CNY 3,600.00 |
|
| RG205621 | UBE2D1 (tGFP-tagged) - Human ubiquitin-conjugating enzyme E2D 1 (UBE2D1), transcript variant 1 |
CNY 2,800.00 |
