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Frizzled 5 (FZD5) (NM_003468) Human Untagged Clone
CAT＃: SC117952
FZD5 (untagged)-Human frizzled family receptor 5 (FZD5)
CNY 6,544.00
| Cited in 2 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | C2orf31; HFZ5 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_003468 edited
GAATTCGGCACGAGGGAGGCAGCGCCTTCCCAAAGCAGTTTATCTTTGGACGGTTTTCTT TAAAGGAAAAAGCAACCAACAGGTTGCCAGCCCCGGCGCCACACACGAGACGCCGGAGGG AGAAGCCCCGGCCCGGATTCCTCTGCCTGTGTGCGTCCCTCGCGGGCTGCTGGAGGCGAG GGGAGGGAGGGGGCGATGGCTCGGCCTGACCCATCCGCGCCGCCCTCGCTGTTGCTGCTG CTCCTGGCGCAGCTGGTGGGCCGGGCGGCCGCCGCGTCCAAGGCCCCGGTGTGCCAGGAA ATCACGGTGCCCATGTGCCGCGGCATCGGCTACAACCTGACGCACATGCCCAACCAGTTC AACCACGACACGCAGGACGAGGCGGGCCTGGAGGTGCACCAGTTCTGGCCGCTGGTGGAG ATCCAATGCTCGCCGGACCTGCGCTTCTTCCTATGCTCTATGTACACGCCCATCTGTCTG CCCGACTACCACAAGCCGCTGCCGCCCTGCCGCTCGGTGTGCGAGCGCGCCAAGGCCGGC TGCTCGCCGCTGATGCGCCAGTACGGCTTCGCCTGGCCCGAGCGCATGAGCTGCGACCGC CTCCCGGTGCTGGGCCGCGACGCCGAGGTCCTCTGCATGGATTACAACCGCAGCGAGGCC ACCACGGCGCCCCCCAGGCCTTTCCCAGCCAAGCCCACCCTTCCAGGCCCGCCAGGGGCG CCGGCCTCGGGGGGCGAATGCCCCGCTGGGGGCCCGTTCGTGTGCAAGTGTCGCGAGCCC TTCGTGCCCATTCTGAAGGAGTCACACCCGCTCTACAACAAGGTGCGGACGGGCCAGGTG CCCAACTGCGCGGTACCCTGCTACCAGCCGTCCTTCAGTGCCGACGAGCGCACGTTCGCC ACCTTCTGGATAGGCCTGTGGTCGGTGCTGTGCTTCATCTCCACGTCCACCACAGTGGCC ACCTTCCTCATCGACATGGAACGCTTCCGCTATCCTGAGCGCCCCATCATCTTCCTGTCA GCCTGCTACCTGTGCGTGTCGCTGGGCTTCCTGGTGCGTCTGGTCGTGGGCCATGCCAGC GTGGCCTGCAGCCGCGAGCACAACCACATCCACTACGAGACCACGGGCCCTGCACTGTGC ACCATCGTCTTCCTCCTGGTCTACTTCTTCGGCATGGCCAGCTCCATCTGGTGGGTCATC CTGTCGCTCACCTGGTTCCTGGCCGCCGGCATGAAGTGGGGCAACGAGGCCATCGCGGGC TACGCGCAGTACTTCCACCTGGCTGCGTGGCTCATCCCCAGCGTCAAGTCCATCACGGCA CTGGCGCTGAGCTCCGTGGACGGGGACCCAGTGGCCGGCATCTGCTACGTGGGCAACCAG AACCTGAACTCGCTGCGCGGCTTCGTGCTGGGCCCGCTGGTGCTCTACCTGCTGGTGGGC ACGCTCTTCCTGCTGGCGGGCTTCGTGTCGCTCTTCCGCATCCGCAGCGTCATCAAGCAG GGCGGCACCAAGACGGACAAGCTGGAGAAGCTCATGATCCGCATCGGCATCTTCACGCTG CTCTATACGGTCCCCGCCAGCATTGTGGTGGCCTGCTACCTGTACGAGCAGCACTACCGC GAGAGCTGGGAGGCGGCGCTCACCTGCGCCTGCCCGGGCCACGACACCGGCCAGCCGCGC GCCAAGCCCGAGTACTGGGTGCTCATGCTCAAGTACTTCATGTGCCTGGTGGTGGGCATC ACGTCGGGCGTCTGGATCTGGTCGGGCAAGACGGTGGAGTCGTGGCGGCGTTTCACCAGC CGCTGCTGCTGCCGCCCGCGGCGCGGCCACAAGAGCGGGGGCGCCATGGCCGCAGGGGAC TACCCCGAGGCGAGCGCCGCGCTCACAGGCAGGACCGGGCCGCCGGGCCCCGCCGCCACC TACCACAAGCAGGTGTCCCTGTCGCACGTGTAGGAGGCTGCCGCCGAGGGACTCGGCCGG AGAGCTGAGGGGAGGGGGGCGTTTTGTTTGGTAGTTTTGCCAAGGTCACTTCCGTTTACC TTCATGGTGCTGTTGCCCCCTCCCGCGGCGACTTGGAGAGAGGGAAGAGGGGCGTTTTCG AGGAAGAACCTGTCCCAGGTCTTCTCCAAGGGGCCCAGCTCACGTGTATTCTATTTTGCG TTTCTTACTGCCTTCTTTATGGGAACCCTCTTTTTAATTTATATGTATTTTTCTTAATTT GTAACTTTGTTGCATTTTGGCAACAATTTACCTTTGCTTTGGGGGCTTTACAATCCTAAG GTTGGCGTTGTAATGAAGTTCCACTTGGTTCAGGTTTCTTTGAACTGTGTGGTCTCAATT GGGAAAATATATTTCCTATACGTGTGTCTTTAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAACTCGAC >OriGene 5' read for NM_003468 unedited
AAAAACCCTCCCCCGCCCGTTGCCGTCTATAGGGCGGTAGCGTGTACGGTGGNGAGTCTA TATAAGCAGAGCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCG GCCGCGAATTCGGCACGAGGGAGGCAGCGCCTTCCCAAAGCAGTTTATCTTTGGACGGTT TTCTTTAAAGGAAAAAGCAACCAACAGGTTGCCTGCCTTGGCGCCACACACGAGACGCCG GAGGGAGAAGCCCCGGCCCGGATTCCTCTGCCTGTGTGCGTCCCTCGCGGGCTGCTGGAG GCGAGGGGAGGGAGGGGGCGATGGCTCGGCCTGACCCATCCGCGCCGCCCTCGCTGTTGC TGCTGCTCCTGGCGCAGCTGGTGGGCCGGGCGGCCGCCGCGTCCAAGGCCCCGGTGTGCC AGGAAATCACGGTGCCCATGTGCCGCGGCATCGGCTACAACCTGACGCACATGCCCAACC AGTTCAACCACGACACGCAGGACGAGGCGGGCCTGGAGGTGCACCAGTTCTGGCCGCTGG TGGAGATCCAATGCTCGCCGGACCTGCGCTTCTTCCTATGCTCTATGTACACGCCCATCT GTCTGCCCGACTACCACAAGCCGCTGCCGCCCTGCCGCTCGGTGTGCGAGCGCGCCAAGG CCGGCTGCTCGCCGCTGATGCGCCAGTACGGCTTCGCCTGGCCCGAGCGCATGAGCTGCG ACCGCCTCCCGGTGCTGGGCCGCGACGCCGAGGTCCTCTGCATGGATTACAACCGCAGCG AGGCCACCCACGGCGCCCCCCAGCCCTTTCCAACCAAGCCACCCTTCCAGGCCGCCAGGG GCGCCGCCTCGGGGGCGAAAGCCCCGCTGGGGGCCCGTTCCTGTGC >OriGene 3' read for NM_003468 unedited
GTCCCATTATGNATGAGGNCACGCATACNATGATCGGTTTTTTTTTTTTTTTTTTTTTTT TTTTTTTTTTTTTTAAAAACCACGTTTAGGGAAATATATTTTCCCAATTGAGACCACACA GTTCAAAAAAACCTGAACCAAGTGGAACTTCATTACAACGCCAACCTTAGGATTGTAAAG CCCCCAAAGCAAAGGTAAATTGTTGCCAAAATGCAACAAAGTTACAAATTAAGAAAAATA CCTATAAATTAAAAAGAGGGTTCCCATAAAGAAGGCAGTAAGAAACGCAAAATAGAATAC ACGTGAGCTGGGCCCCTTGGAGAAAACCTGGGACAGGTTCTTCCTCGAAAACGCCCCTTT TTCCTTTCTCCAAGTCGCCGCGGGAGGGGGCAACAGCACCATGAAGGTAAACGGAAGTGA CCTTGGCAAAACTACCAAACAAAACGCCCCCCTCCCCTTAACTCTCCGGCCGAGTCCCTC GGCGGGAGCCTCCTACACGTGCGACAGGGACACCTGCTTGTGGTAAGTGGCGGCGGGGCC CGGCGGCCCGGTCCTGCCTGTGAGCCGGGGCTCGCCTCGGGGTAATCCCCTGGGGCCTGG GGCCCCCGCTCTTGTGGCCGCGCCCGGGCGGGAACAACAACGGGTGGGGAAACCCCGCCC CGACTCCACCGGTTTTGTCCGAACAAATTCAGAACCCCGAGGTGTTGCCCCCCACCAGGC ACATGGAAGTACTTGGACATGGACACCCATTCCTCGGCCTTGGCCCCCGGTTGGCCCGGT TTTTTGGCCCGGGAAGCCCCAGGTTGACCCCCCCTTCCCACTCTTTCGGGAATGCCGCCC CTACAAGGTTGAAGGCCCCCCAAGGGTTGGGGGGGCCCGCTTTAAGCAG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_003468 |
| Insert Size | 2500 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_003468.2, NP_003459.2 |
| RefSeq Size | 2561 bp |
| RefSeq ORF | 1758 bp |
| Locus ID | 7855 |
| UniProt ID | Q13467 |
| Domains | FRI, Frizzled |
| Protein Families | Druggable Genome, GPCR, Transmembrane |
| Protein Pathways | Basal cell carcinoma, Colorectal cancer, Melanogenesis, Pathways in cancer, Wnt signaling pathway |
| Gene Summary | Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD5 protein is believed to be the receptor for the Wnt5A ligand. [provided by RefSeq, Jul 2008] |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
A GTPase-activating protein binding protein (G3BP1) / antiviral protein relay conveys arteriosclerotic Wnt signals in aortic smooth muscle cells
,Ramachandran, B;Stabley, JN;Cheng, SL;Behrmann, AS;Gay, A;Li, L;Mead, M;Kozlitina, J;Lemoff, A;Mirzaei, H;Chen, Z;Towler, DA;,
J. Biol. Chem.
,PubMed ID 29626090
[FZD5]
|
|
R-Spondin1 regulates Wnt signaling by inhibiting internalization of LRP6
,ME Binnerts, KA Kim, JM Bright, SM Patel, K Tran, M Zhou, JM Leung, Y Liu, WE Lomas 3rd, M Dixon, SA Hazell, M Wagle, WS Nie, N Tomasevic, J Williams, X Zhan, MD Levy, WD Funk, and A Abo,
Proc Natl Acad Sci U S A. 2007 Sep 11;104(37):14700-5.
[FZD5]
|
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC213960 | FZD5 (Myc-DDK-tagged)-Human frizzled family receptor 5 (FZD5) |
CNY 6,536.00 |
|
| RC213960L1 | Lenti ORF clone of Human frizzled family receptor 5 (FZD5), Myc-DDK-tagged |
CNY 8,936.00 |
|
| RC213960L2 | Lenti ORF clone of Human frizzled family receptor 5 (FZD5), mGFP tagged |
CNY 8,936.00 |
|
| RC213960L3 | Lenti ORF clone of Human frizzled family receptor 5 (FZD5), Myc-DDK-tagged |
CNY 7,030.00 |
|
| RC213960L4 | Lenti ORF clone of Human frizzled family receptor 5 (FZD5), mGFP tagged |
CNY 7,030.00 |
|
| RG213960 | FZD5 (tGFP-tagged) - Human frizzled family receptor 5 (FZD5) |
CNY 8,136.00 |
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