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Frizzled homolog 1 (FZD1) (NM_003505) Human Untagged Clone
CAT＃: SC117910
FZD1 (untagged)-Human frizzled family receptor 1 (FZD1)
CNY 4,824.00
| Cited in 4 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_003505 edited
GAATTCGGCACGAGGCGGCGGCGGAGAAGGAGGCGGAGGCGCAGGGGGGAGCCGAGCCCG CTGGGCTGCGGAGAGTTGCGCTCTCTACGGGGCCGCGGCCACTAGCGCGGCGCCGCCAGC CGGGAGCCAGCGAGCCGAGGGCCAGGAAGGCGGGACACGACCCCGGCGCGCCCTAGCCAC CCGGGTTCTCCCCGCCGCCCGCGCTTCATGAATCGCAAGTTTCCGCGGCGGCGGCGGCTG CGGTACGCAGAACAGGAGCCGGGGGAGCGGGCCGAAAGCGGCTTGGGCTCGACGGAGGGC ACCCGCGCAGAGGTCTCCCTGGCCGCAGGGGGAGCCGCCGCCGGCCGTGCCCCTGGCAGC CCCAGCGGAGCGGCGCCAAGAGAGGAGCCGAGAAAGTATGGCTGAGGAGGAGGCGCCTAA GAAGTCCCGGGCCGCCGGCGGTGGCGCGAGCTGGGAACTTTGTGCCGGGGCGCTCTCGGC CCGGCTGGCGGAGGAGGGCAGCGGGGACGCCGGTGGCCGCCGCCGCCCGCCAGTTGACCC CCGGCGATTGGCGCGCCAGCTGCTGCTGCTGCTTTGGCTGCTGGAGGCTCCGCTGCTGCT GGGGGTCCGGGCCCAGGCGGCGGGCCAGGGGCCAGGCCAGGGGCCCGGGCCGGGGCAGCA ACCGCCGCCGCCGCCTCAGCAGCAACAGAGCGGGCAGCAGTACAACGGCGAGCGGGGCAT CTCCGTCCCGGACCACGGCTATTGCCAGCCCATCTCCATCCCGCTGTGCACGGACATCGC GTACAACCAGACCATCATGCCCAACCTGCTGGGCCACACGAACCAGGAGGACGCGGGCCT GGAGGTGCACCAGTTCTACCCTCTAGTGAAAGTGCAGTGTTCCGCTGAGCTCAAGTTCTT CCTGTGCTCCATGTACGCGCCCGTGTGCACCGTGCTAGAGCAGGCGCTGCCGCCCTGCCG CTCCCTGTGCGAGCGCGCGCGCCAGGGCTGCGAGGCGCTCATGAACAAGTTCGGCTTCCA GTGGCCAGACACGCTCAAGTGTGAGAAGTTCCCGGTGCACGGCGCCGGCGAGCTGTGCGT GGGCCAGAACACGTCCGACAAGGGCACCCCGACGCCCTCGCTGCTTCCAGAGTTCTGGAC CAGCAACCCTCAGCACGGCGGCGGAGGGCACCGTGGCGGCTTCCCGGGGGGCGCCGGCGC GTCGGAGCGAGGCAAGTTCTCCTGCCCGCGCGCCCTCAAGGTGCCCTCCTACCTCAACTA CCACTTCCTGGGGGAGAAGGACTGCGGCGCACCTTGTGAGCCGACCAAGGTGTATGGGCT CATGTACTTCGGGCCCGAGGAGCTGCGCTTCTCGCGCACCTGGATTGGCATTTGGTCAGT GCTGTGCTGCGCCTCCACGCTCTTCACGGTGCTTACGTACCTGGTGGACATGCGGCGCTT CAGCTACCCGGAGCGGCCCATCATCTTCTTGTCCGGCTGTTACACGGCCGTGGCCGTGGC CTACATCGCCGGCTTCCTCCTGGAAGACCGAGTGGTGTGTAATGACAAGTTCGCCGAGGA CGGGGCACGCACTGTGGCGCAGGGCACCAAGAAGGAGGGCTGCACCATCCTCTTCATGAT GCTCTACTTCTTCAGCATGGCCAGCTCCATCTGGTGGGTGATCCTGTCGCTCACCTGGTT CCTGGCGGCTGGCATGAAGTGGGGCCACGAGGCCATCGAAGCCAACTCACAGTATTTTCA CCTGGCCGCCTGGGCTGTGCCGGCCATCAAGACCATCACCATCCTGGCGCTGGGCCAGGT GGACGGCGATGTGCTGAGCGGAGTGTGCTTCGTGGGGCTTAACAACGTGGACGCGCTGCG TGGCTTCGTGCTGGCGCCCCTCTTCGTGTACCTGTTTATCGGCACGTCCTTTCTGCTGGC CGGCTTTGTGTCGCTCTTCCGCATCCGCACCATCATGAAGCACGATGGCACCAAGACCGA GAAGCTGGAGAAGCTCATGGTGCGCATTGGCGTCTTCAGCGTGCTGTACACTGTGCCAGC CACCATCGTCATCGCCTGCTACTTCTACGAGCAGGCCTTCCGGGACCAGTGGGAACGCAG CTGGGTGGCCCAGAGCTGCAAGAGCTACGCTATCCCCTGCCCTCACCTCCAGGCGGGCGG AGGCGCCCCGCCGCACCCGCCCATGAGCCCGGACTTCACGGTCTTCATGATTAAGTACCT TATGACGCTGATCGTGGGCATCACGTCGGGCTTCTGGATCTGGTCCGGCAAGACCCTCAA CTCCTGGAGGAAGTTCTACACGAGGCTCACCAACAGCAAACAAGGGGAGACTACAGTCTG AGACCCGGGGCTCAGCCCATGCCCAGGCCTCGGCCGGGGCGCAGCGATCCCCCAAAGCCA GCGCCGTGGAGTTCGTGCCAATCCTGACATCTCGAGGTTTCCTCACTAGACAACTCTCTT TCGCAGGCTCCTTTGAACAACTCAGCTCCTGCAAAAGCTTCCGTCCCTGAGGCAAAAGGA CACGAGGGCCCGACTGCCAGAGGGAGGATGGACAGACCTCTTGCCCTCACACTCTGGTAC CAGGACTGTTCGCTTTTATGATTGTAAATAGCCTGTGTAAGATTTTTGTAAGTATATTTG TATTTAAATGACGACCGATCACGCGTTTTTCTTTTTCAAAAGTTTTTAATTATTTAGGGC GGTTTAACCATTTGAGGCTTTTCCTTCTTGCCCTTTTCGGAGTATTGCAAAGGAGCTAAA ACTGGTGTGCAACCGCACAGCGCTCCTGGTCGTCCTCGCGCGCCTCTCCCTACCACGGGT GCTCGGGACGGCTGGGCGCCAGCTCCGGGGCGAGTTCAGCACTGCGGGGTGCGACTAGGG CTGCGCTGCCAGGGTCACTTCCCGCCTCCTCCTTTTGCCCCCTCCCCCTCCTTCTGTCCC CTCCCTTTCTTTCCTGGCTTGAGGTAGGGGCTCTTAAGGTACAGAACTCCACAAACCTTC CAAATCTGGAGGAGGGCCCCCATACATTACAATTCCTCCCTTGCTCGGCGGTGGATTGCG AAGGCCCGTCCCTTCGACTTCCTGAAGCTGGATTTTTAACTGTCCAGAACTTTCCTCCAA CTTCATGGGGGCCCACGGGTGTGGGCGCTGGCAGTCTCAGCCTCCCTCCACGGTCACCTT CAACGCCCAGACACTCCCTTCTCCCACCTTAGTTGGTTACAGGGTGAGTGAGATAACCAA TGCCAAACTTTTTGAAGTCTAATTTTTGAGGGGTGAGCTCATTTCATTCTCTAGTGTCTA AAACCTGGTATGGGTTTGGCCAGCGTCATGGAAAGATGTGGTTACTGAGATTTGGGAAGA AGCATGAAGCTTTGTGTGGGTTGGAAGAGACTGAAGATATGGGTTATAAAATGTTAATTC TAATTGCATACGGATGCCTGGCAACCTTGCCTTTGAGAATGAGACAGCCTGCGCTTAGAT TTTACCGGTCTGTAAAATGGAAATGTTGAGGTCACCTGGAAAGCTTTGTTAAGGAGTTGA TGTTTGCTTTCCTTAACAAGACAGCAAAACGTAAACAGAAATTGAAAACTTGAAGGATAT TTCAGTGTCATGGACTTCCTCAAAATGAAGTGCTATTTTCTTATTTTTAATCAAATAACT AGACATATATCAGAAACTTTAAAATGTAAAAGTTGTACACTTTCAACATTTTATTACGAT TATTATTCAGCAGCACATTCTGAGGGGGGAACAATTCACACCACCAATAATAACCTGGTA AGATTTCAGGAGGTAAAGAAGGTGGAATAATTGACGGGGAGATAGCGCCTGAAATAAACA AAATATGGGCATGCATGCTAAAGGGAAAATGTGTGCAGGTCTACTGCATTAAATCCTGTG TGCTCCTCTTTTGGATTTACAGAAATGTGTCAAATGTAAATCTTTCAAAGCCATTTAAAA ATATTCACTTTAGTTCTCTGTGAAGAAGAGGAGAAAAGCAATCCTCCTGATTGTATTGTT TTAAACTTTAAGAATTTATCAAAATGCCGGTACTTAGGACCTAAATTTATCTATGTCTGT CATACGCTAAAATGATATTGGTCTTTGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAACTCGAC >OriGene 5' read for NM_003505 unedited
TGTATACGACTACTATAGGGCGGCCGCGATTCGGCACGAGGCGGCGGCGGAGAAGAGCGG GGCGCAGGGGGAGCCGAGCCCGCTGGGCTGCGGAGAGTTGCGCTCTCTACGGGGCCGCGG CCACTAGCGCGGCGCCGCCAGCCGGGAGCCAGCGAGCCGAGGGCCAGGAAGGCGGGACAC GACCCCGGCGCGCCCTAGCCACCCGGGTTCTCCCCGCCGCCCGCGCTTCATGAATCGCAA GTTTCCGCGGCGGCGGCGGCTGCGGTACGCAGAACAGGAGCCGGGGGAGCGGGCCGAAAG CGGCTTGGGCTCGACGGAGGGCACCCGCGCAGAGGTCTCCCTGGCCGCAGGGGGAGCCGC CGCCGGCCGTGCCCCTGGCAGCCCCAGCGGAGCGGCGCCAAGAGAGGAGCCGAGAAAGTA TGGCTGAGGAGGAGGCGCCTAAGAAGTCCCGGGCCGCCGGCGGTGGCGCGAGCTGGGAAC TTTGTGCCGGGGCGCTCTCGGCCCGGCTGGCGGAGGAGGGCAGCGGGGACGCCGGTGGCC GCCGCCGCCCGCCAGTTGACCCCCGGCGATTGGCGCGCCAGCTGCTGCTGCTGCTTTGGC TGCTGGAGGCTCCGCTGCTGCTGGGGGTCCGGGCCCAGGCGGCGGGCCAGGGGCCAGGCC AGGGGCCCGGGCCGGGGCAGCAACCGCCGCCGCCGCCTCAGCAGCAACAGAGCGGGCAGC AGTACAACGGCGAGCGGGGCATCTNCGTCCCGGACCCGGCTATTGCCAGCCCATCTCCAT CCCGCTGTGCACGGACATCGCGTACACCAGACCATCATGCCCAACCTGCTGGGCCACACG AACCAGAGGACGCGGGCCTGGAGTGCACAGTTCTACCCTTANTGAAGTGCAGTGTTCGCT GAN >OriGene 3' read for NM_003505 unedited
ATCAGGTTCATTTTACCGNTATACAGGACTAGNTAAATTTACGGTCCTAAGTACCGGCAT TTTGTATAAATTCTTAAAGTTTAAAACAATACAATCAGGAGGATTGCTTTTCTCCTCTTC TTCACAGAGAACTAAAGTGAATATTTTTAAATGGCTTTGAAAGATTTACATTTGACACAT TTCTGTAAATCCAAAAGAGGAGCACACAGGATTTATATCTTTAGACCTGCACACATTTTC CCTTTAGCAAGCATGCCCATATTTTGTTTATTTCAGGCGCTATCTCCCCGTCAATTATTC CACCTTCTTTACCTCCTGAAATCTTACCAGGTTATTATTGGTGGTGTGAATTGTTCCCCC CTCAGAATGTGCTGCTGAATAATAATCGTAATAAAATGTTGAAAGTGTACAACTTTTACA TTTTAAAGTTTCTGATATATGTCTAGTTATTTGATTAAAAATAAGACAATAGCACTTCAT TTTGAGGAAGTCCATGACACTGAAATATCCTTCAAGTTTTCAATTTCTGTTTACGTTATG CTGGCTTGTTAAGGAAAGCAAACATCAACTCCTTAACAAAGCTTTCCAGGTGACCTCAAC ATTTCCATTTTACAGACCCGTAAAATCTAAGCGCAAGCTGTCTCATTCTCAAAGGCCAAG GTGCCAAGCTTCCCGTATCCATTTAGAATTTACATTTTATAACCCCATTATCTTCAGTCC CTTTTCAACCCACACAAAGCTTAATGCTTTTTCCCAAATCTCGATAACCACATTTTTTCC TGAACCTGGGCAAACCCATACCAGGGTTTATAACCCTTGGAATGGTATGAGGCCTCCCCC TTAAAAATTTAAACTTCAAAAATTTTGGCTATTGGTTATACACCTCCCCCTGTACCCACT AAAGGTGTGGAAAGGGAGAGTTCTGCGCCCTTTAACGGTTCCCGGGTGAGGAGGGTCTAG AATTGACCGGGCCCCGCC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_003505 |
| Insert Size | 4300 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_003505.1, NP_003496.1 |
| RefSeq Size | 4350 bp |
| RefSeq ORF | 1944 bp |
| Locus ID | 8321 |
| UniProt ID | Q9UP38 |
| Domains | FRI, Frizzled |
| Protein Families | Druggable Genome, GPCR, Transmembrane |
| Protein Pathways | Basal cell carcinoma, Colorectal cancer, Melanogenesis, Pathways in cancer, Wnt signaling pathway |
| Gene Summary | Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD1 protein contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, 7 transmembrane domains, and a C-terminal PDZ domain-binding motif. The FZD1 transcript is expressed in various tissues. [provided by RefSeq, Jul 2008] |
Citations (4)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Mapping of Wnt-Frizzled interactions by multiplex CRISPR targeting of receptor gene families
,Voloshanenko, O;Gmach, P;Winter, J;Kranz, D;Boutros, M;,
FASEB J.
,PubMed ID 28733458
[FZD1]
|
|
ß-Catenin-dependent pathway activation by both promiscuous canonical WNT3a-, and specific noncanonical WNT4- and WNT5a-FZD receptor combinations with strong differences in LRP5 and LRP6 dependency
,Ring, L;Neth, P;Weber, C;Steffens, S;Faussner, A;,
Cell. Signal.
,PubMed ID 24269653
[FZD1]
|
|
Secreted Frizzled-related protein-1 is a negative regulator of androgen receptor activity in prostate cancer
,Y Kawano, S Diez, P Uysal-Onganer, R S Darrington, J Waxman, R M Kypta,
British Journal of Cancer 100, 1165-1174 (10 March 2009)
[FZD1]
|
|
R-Spondin1 regulates Wnt signaling by inhibiting internalization of LRP6
,ME Binnerts, KA Kim, JM Bright, SM Patel, K Tran, M Zhou, JM Leung, Y Liu, WE Lomas 3rd, M Dixon, SA Hazell, M Wagle, WS Nie, N Tomasevic, J Williams, X Zhan, MD Levy, WD Funk, and A Abo,
Proc Natl Acad Sci U S A. 2007 Sep 11;104(37):14700-5.
[FZD1]
|
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC208603 | FZD1 (Myc-DDK-tagged)-Human frizzled family receptor 1 (FZD1) |
CNY 4,816.00 |
|
| RC208603L1 | Lenti-ORF clone of FZD1 (Myc-DDK-tagged)-Human frizzled family receptor 1 (FZD1) |
CNY 7,216.00 |
|
| RC208603L2 | Lenti-ORF clone of FZD1 (mGFP-tagged)-Human frizzled family receptor 1 (FZD1) |
CNY 5,890.00 |
|
| RC208603L3 | Lenti-ORF clone of FZD1 (Myc-DDK-tagged)-Human frizzled family receptor 1 (FZD1) |
CNY 5,890.00 |
|
| RC208603L4 | Lenti-ORF clone of FZD1 (mGFP-tagged)-Human frizzled family receptor 1 (FZD1) |
CNY 5,890.00 |
|
| RG208603 | FZD1 (tGFP-tagged) - Human frizzled family receptor 1 (FZD1) |
CNY 6,416.00 |
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