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CILP (NM_003613) Human Untagged Clone
CAT＃: SC117885
CILP (untagged)-Human cartilage intermediate layer protein, nucleotide pyrophosphohydrolase (CILP)
CNY 8,248.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CILP-1; HsT18872 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC117885 sequence for NM_003613 edited (data generated by NextGen Sequencing)
ATGGTGGGGACCAAGGCCTGGGTGTTCTCCTTCCTGGTCCTGGAAGTCACATCTGTGTTG GGGAGACAGACGATGCTCACCCAGTCAGTAAGAAGAGTCCAGCCTGGGAAGAAGAACCCC AGCATCTTTGCCAAGCCTGCCGACACCCTGGAGAGCCCTGGTGAGTGGACAACATGGTTC AACATCGACTACCCAGGCGGGAAGGGCGACTATGAGCGGCTGGACGCCATTCGCTTCTAC TATGGGGACCGTGTATGTGCCCGTCCCCTGCGGCTAGAGGCTCGGACCACTGACTGGACA CCTGCGGGCAGCACTGGCCAGGTGGTCCATGGTAGTCCCCGTGAGGGTTTCTGGTGCCTC AACAGGGAGCAGCGGCCTGGCCAGAACTGCTCTAATTACACCGTACGCTTCCTCTGCCCA CCAGGATCCCTGCGCCGAGACACAGAGCGCATCTGGAGCCCATGGTCTCCCTGGAGCAAG TGCTCAGCTGCCTGTGGTCAGACTGGGGTCCAGACTCGCACACGCATTTGCTTGGCAGAG ATGGTGTCGCTGTGCAGTGAGGCCAGCGAAGAGGGTCAGCACTGCATGGGCCAGGACTGT ACAGCCTGTGACCTGACCTGCCCAATGGGCCAGGTGAATGCTGACTGTGATGCCTGCATG TGCCAGGACTTCATGCTTCATGGGGCTGTCTCCCTTCCCGGAGGTGCCCCAGCCTCAGGG GCTGCTATCTACCTCCTGACCAAGACGCCGAAGCTGCTGACCCAGACAGACAGTGATGGG AGATTCCGAATCCCTGGCTTGTGCCCTGATGGCAAAAGCATCCTGAAGATCACAAAGGTC AAGTTTGCCCCCATTGTACTCACAATGCCCAAGACTAGCCTGAAGGCAGCCACCATCAAG GCAGAGTTTGTGAGGGCAGAGACTCCATACATGGTGATGAACCCTGAGACAAAAGCACGG AGAGCTGGGCAGAGCGTGTCTCTGTGCTGTAAGGCCACAGGGAAGCCCAGGCCAGACAAG TATTTTTGGTATCATAATGACACATTGCTGGATCCTTCCCTCTACAAGCATGAGAGCAAG CTGGTGCTGAGGAAACTGCAGCAGCACCAGGCTGGGGAGTACTTTTGCAAGGCCCAGAGT GATGCTGGGGCTGTGAAGTCCAAGGTTGCCCAGCTGATTGTCATAGCATCTGATGAGACT CCTTGCAACCCAGTTCCTGAGAGCTATCTTATCCGGCTGCCCCATGATTGCTTTCAGAAT GCCACCAACTCCTTCTACTATGACGTGGGACGCTGCCCTGTTAAGACTTGTGCAGGGCAG CAGGATAATGGGATCAGGTGCCGTGATGCTGTGCAGAACTGCTGTGGCATCTCCAAGACA GAGGAAAGGGAGATCCAGTGCAGTGGCTACACGCTACCCACCAAGGTGGCCAAGGAGTGC AGCTGCCAGCGGTGTACGGAAACTCGGAGCATCGTGCGGGGCCGTGTCAGTGCTGCTGAC AATGGGGAGCCCATGCGCTTTGGCCATGTGTACATGGGGAACAGCCGTGTAAGCATGACT GGCTACAAGGGCACTTTCACCCTCCATGTCCCCCAGGACACTGAGAGGCTGGTGCTCACA TTTGTGGACAGGCTGCAGAAGTTTGTCAACACCACCAAAGTGCTACCTTTCAACAAGAAG GGGAGTGCCGTGTTCCATGAAATCAAGATGCTTCGTCGGAAAGAGCCCATCACTTTGGAA GCCATGGAGACCAACATCATCCCCCTGGGGGAAGTGGTTGGTGAAGACCCCATGGCTGAA CTGGAGATTCCATCCAGGAGTTTCTACAGGCAGAATGGGGAGCCCTACATAGGAAAAGTG AAGGCCAGTGTGACCTTCCTGGATCCCCGGAATATTTCCACAGCCACAGCTGCCCAGACT GACCTGAACTTCATCAATGACGAAGGAGACACTTTCCCCCTTCGGACGTATGGCATGTTC TCTGTGGACTTCAGAGATGAGGTCACCTCAGAGCCACTTAATGCTGGCAAAGTGAAGGTC CACCTTGACTCGACCCAGGTCAAGATGCCAGAGCACATATCCACAGTGAAACTCTGGTCA CTCAATCCAGACACAGGGCTGTGGGAGGAGGAAGGTGATTTCAAATTTGAAAATCAAAGG AGGAACAAAAGAGAAGACAGAACCTTCCTGGTGGGCAACCTGGAGATTCGTGAGAGGAGG CTCTTTAACCTGGATGTTCCTGAAAGCAGGCGGTGCTTTGTTAAGGTGAGGGCCTACCGG AGTGAGAGGTTCTTGCCTAGTGAGCAGATCCAGGGGGTTGTGATCTCCGTGATTAACCTG GAGCCTAGAACTGGCTTCTTGTCCAACCCTAGGGCCTGGGGCCGCTTTGACAGTGTCATC ACAGGCCCCAACGGGGCCTGTGTGCCTGCCTTCTGTGATGACCAGTCCCCTGATGCCTAC TCTGCCTATGTCTTGGCAAGCCTGGCTGGGGAGGAACTGCAAGCAGTGGAGTCTTCTCCT AAATTCAACCCAAATGCAATTGGCGTCCCTCAGCCCTATCTCAACAAGCTCAACTACCGT CGGACGGACCATGAGGATCCACGGGTTAAAAAGACAGCTTTCCAGATTAGCATGGCCAAG CCAAGGCCCAACTCAGCTGAGGAGAGCAATGGGCCCATCTATGCCTTTGAGAACCTCCGG GCATGTGAAGAGGCACCACCCAGTGCAGCCCACTTCCGGTTCTACCAGATTGAGGGGGAT CGATATGACTACAACACAGTCCCCTTCAACGAAGATGACCCTATGAGCTGGACTGAAGAC TATCTGGCATGGTGGCCAAAGCCGATGGAATTCAGGGCCTGCTATATCAAGGTGAAGATT GTGGGGCCACTGGAAGTGAATGTGCGATCCCGCAACATGGGGGGCACTCATCGGCGGACA GTGGGGAAGCTGTATGGAATCCGAGATGTGAGGAGCACTCGGGACAGGGACCAGCCCAAT GTCTCAGCTGCCTGTCTGGAGTTCAAGTGCAGTGGGATGCTCTATGATCAGGACCGTGTG GACCGCACCCTGGTGAAGGTCATCCCCCAGGGCAGCTGCCGTCGAGCCAGTGTGAACCCC ATGCTGCATGAGTACCTGGTCAACCACTTGCCACTTGCAGTCAACAACGACACCAGTGAG TACACCATGCTGGCACCCTTGGACCCACTGGGCCACAACTATGGCATCTACACTGTCACT GACCAGGACCCTCGCACGGCCAAGGAGATCGCGCTCGGCCGGTGCTTTGATGGCACATCC GATGGCTCCTCCAGAATCATGAAGAGCAATGTGGGAGTAGCCCTCACCTTCAACTGTGTA GAGAGGCAAGTAGGCCGCCAGAGTGCCTTCCAGTACCTCCAAAGCACCCCAGCCCAGTCC CCTGCTGCAGGCACTGTCCAAGGAAGAGTGCCCTCGAGGAGGCAGCAGCGAGCGAGCAGG GGTGGCCAGCGCCAGAGTGGAGTGGTGGCCTCTCTGAGATTTCCTAGAGTTGCTCAACAG CCCCTGATCAACTAA Clone variation with respect to NM_003613.3 2936 a=>g;3496 g=>a >OriGene 5' read for NM_003613 unedited
GGTCAGGATTTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGGCAGCTGAGG AGTCCTGCTCAAAACACGGTCACTGGATCTGAGAACTTCCCAGGGGACCGCATTCCAGAG TCAGTGACTCTGTGAAGCACCCACATCTACCTCTTGCCACGTTCCCACGGGCTTGGGGGA AAGATGGTGGGGACCAAGGCCTGGGTGTTCTCCTTCCTGGTCCTGGAAGTCACATCTGTG TTGGGGAGACAGACGATGCTCACCCAGTCAGTAAGAAGAGTCCAGCCTGGGAAGAAGAAC CCCAGCATCTTTGCCAAGCCTGCCGACACCCTGGAGAGCCCTGGTGAGTGGACAACATGG TTCAACATCGACTACCCAGGCGGGAAGGGCGACTATGAGCGGCTGGACGCCATTCGCTTC TACTATGGGGACCGTGTATGTGCCCGTCCCCTGCGGCTAGAGGCTCGGACCACTGACTGG ACACCTGCGGGCAGCACTGGCCAGGTGGTCCATGGTAGTCCCCGTGAGGGTTTCTGGTGC CTCAACAGGGAGCAGCGGCCTGGCCAGAACTGCTCTAATTACACCGTACGCTTCCTCTGC CCACCAGGATCCCTGCGCCGAGACACAGAGCGCATCTGGAGCCCATGGTCTCCCTGGAGC AAGTGCTCAGCTGCCTGTGGTCAGACTGGGGTCCAGACTCGCACACGCATTTGCTTGGCA GAGATGGTGTCGCTGTGCAGTGAGGCCAGCGAAGAGGGTCAGCACTGCATGGGCCAGGAC TGTACAGCCTGTGACCTGACCTGCCCAATGGGCCANGTGAATGCTGACTGTGATGCCTGC ATGTGCCANGACTTCATGCTTCATGGGGCTGTCTCCTTTNCCGNAGTGCCCCAGCTCAGG GGCTGCTATCTACTCCTGACN >OriGene 3' read for NM_003613 unedited
GCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTACAGAGTATGCATTT ATTGACATCTGCCCTGGGCTACACTGGGTTTCTAGCAAGAACAAAAGCGAATGCAAAGGG AAATGTACAAATACAGTTAGCAACCTGGTGTAATTGGGGATACCAGGAGATGTTCTTTCC AGACTTGGTAGAGGAACTATGATCACCCTATATTTAATAGCTTAACTTTGAATGTGCACT AAAATTCCAAATTTAGCAAAGAAATAAATAAGTTATTTACATTTCAAGTAAAAGTATTGG GTTTTATTTCTTTATTTCACCACCATTTATATGTATGAACTATGATCAAGGCTTGCCTAT GTCCTGTGGAGCAAGGCCAAGAAATATGCTTTATATTGGTTATTTGATCTTCAGCATCAG ATTATCACTATTGCAGAGGTGGGCAAAACCATGCAAAAAGAAGAGGAAGTATATTTGCAT TAATGGCATTAAATGAAGTACAGTTGAAGCTGCAGAGTTTTACCAGTGGCCAATTTCTTG TGTTTCATTAAAAGAACATGTTCACAAAGGGGCCTTATTGTGCCATTGTGGGGGGCACGT GCCATTCTTTGCCTGGGACAAAGTAAGTAAAGGCTCGAACAACCATCAGTCATATCCCGA AAACAAAATGCCTAAATAAACCAAGGGACAGTTGGCCTTACTTTCACAAGGGTTGTTATG GAATGAGGGGCGACAAGGCGCATTACCCCACACCTATTGCTCACGCGCGGCTGGTCACTT TAGGAATTCTATAAGGGCACCTTNCCTCTGGCCCGTGCACCCCCGCTCCTACACTCCGCT TTCAACACGGCTTCCCCCTCATCTCTCTCCTAAACGGCCGCCGCGAGCGCCTTCCTGTTC TTAACGACTCTCTCGCCCACTCCTCTCCCCTTTTGGACTAGGCCTCCTCTCACTCTCTCC ATTTCCTGCCTACCCGTG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_003613 |
| Insert Size | 4760 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_003613.2, NP_003604.2 |
| RefSeq Size | 4436 bp |
| RefSeq ORF | 3555 bp |
| Locus ID | 8483 |
| UniProt ID | O75339 |
| Domains | tsp_1, ig, IGc2, IG |
| Protein Families | Druggable Genome, Phosphatase, Secreted Protein |
| Gene Summary | Major alterations in the composition of the cartilage extracellular matrix occur in joint disease, such as osteoarthrosis. This gene encodes the cartilage intermediate layer protein (CILP), which increases in early osteoarthrosis cartilage. The encoded protein was thought to encode a protein precursor for two different proteins; an N-terminal CILP and a C-terminal homolog of NTPPHase, however, later studies identified no nucleotide pyrophosphatase phosphodiesterase (NPP) activity. The full-length and the N-terminal domain of this protein was shown to function as an IGF-1 antagonist. An allelic variant of this gene has been associated with lumbar disc disease. [provided by RefSeq, Sep 2010] |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC207801 | CILP (Myc-DDK-tagged)-Human cartilage intermediate layer protein, nucleotide pyrophosphohydrolase (CILP) |
CNY 12,368.00 |
|
| RC207801L1 | Lenti ORF clone of Human cartilage intermediate layer protein, nucleotide pyrophosphohydrolase (CILP), Myc-DDK-tagged |
CNY 13,680.00 |
|
| RC207801L2 | Lenti ORF clone of Human cartilage intermediate layer protein, nucleotide pyrophosphohydrolase (CILP), mGFP tagged |
CNY 14,768.00 |
|
| RC207801L3 | Lenti ORF clone of Human cartilage intermediate layer protein, nucleotide pyrophosphohydrolase (CILP), Myc-DDK-tagged |
CNY 13,680.00 |
|
| RC207801L4 | Lenti ORF clone of Human cartilage intermediate layer protein, nucleotide pyrophosphohydrolase (CILP), mGFP tagged |
CNY 13,680.00 |
|
| RG207801 | CILP (tGFP-tagged) - Human cartilage intermediate layer protein, nucleotide pyrophosphohydrolase (CILP) |
CNY 13,968.00 |
