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kynurenine 3 monooxygenase (KMO) (NM_003679) Human Untagged Clone
CAT＃: SC117858
KMO (untagged)-Human kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) (KMO)
CNY 3,656.00
CNY 7,790.00
| Cited in 2 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | dJ317G22.1 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC117858 sequence for NM_003679 edited (data generated by NextGen Sequencing)
ATGGACTCATCTGTCATTCAAAGGAAAAAAGTAGCTGTCATTGGTGGTGGCTTGGTTGGC TCATTACAAGCATGCTTTCTTGCAAAGAGGAATTTCCAGATTGATGTATATGAAGCTAGG GAAGATACTCGAGTGGCTACCTTCACACGTGGAAGAAGCATTAACTTAGCCCTTTCTCAT AGAGGACGACAAGCCTTGAAAGCTGTTGGCCTGGAAGATCAGATTGTATCCCAAGGTATT CCCATGAGAGCAAGAATGATCCACTCTCTTTCAGGAAAAAAGTCTGCAATTCCCTATGGG ACAAAGTCTCAGTATATTCTTTCTGTAAGCAGAGAAAATCTAAACAAGGATCTATTGACT GCTGCTGAGAAATACCCCAATGTGAAAATGCACTTTAACCACAGGCTGTTGAAATGTAAT CCAGAGGAAGGAATGATCACAGTGCTTGGATCTGACAAAGTTCCCAAAGATGTCACTTGT GACCTCATTGTAGGATGTGATGGAGCCTATTCAACTGTCAGATCTCACCTGATGAAGAAA CCTCGCTTTGATTACAGTCAGCAGTACATTCCTCATGGGTACATGGAGTTGACTATTCCA CCTAAGAACGGAGATTATGCCATGGAACCTAATTATCTGCATATTTGGCCTAGAAATACC TTTATGATGATTGCACTTCCTAACATGAACAAATCATTCACATGTACTTTGTTCATGCCC TTTGAAGAGTTTGAAAAACTTCTAACCAGTAATGATGTGGTAGATTTCTTCCAGAAATAC TTTCCAGATGCCATCCCTCTAATTGGAGAGAAACTCCTAGTGCAAGATTTCTTCCTGTTG CCTGCCCAGCCCATGATATCTGTAAAGTGCTCTTCATTTCACTTTAAATCTCACTGTGTA CTGCTGGGAGATGCAGCTCATGCTATAGTGCCGTTTTTTGGGCAAGGAATGAATGCGGGC TTTGAAGACTGCTTGGTATTTGATGAGTTAATGGATAAATTCAGTAACGACCTTAGTTTG TGTCTTCCTGTGTTCTCAAGATTGAGAATCCCAGATGATCACGCGATTTCAGACCTATCC ATGTACAATTACATAGAGATGCGAGCACATGTCAACTCAAGCTGGTTCATTTTTCAGAAG AACATGGAGAGATTTCTTCATGCGATTATGCCATCGACCTTTATCCCTCTCTATACAATG GTCACTTTTTCCAGAATAAGATACCATGAGGCTGTGCAGCGTTGGCATTGGCAAAAAAAG GTGATAAACAAAGGACTCTTTTTCTTGGGATCACTGATAGCCATCAGCAGTACCTACCTA CTTATACACTACATGTCACCACGATCTTTCCTCTGCTTGAGAAGACCATGGAACTGGATA GCTCACTTCCGGAATACAACATGTTTCCCCGCAAAGGCCGTGGACTCCCTAGAACAAATT TCCAATCTCATTAGCAGGTGA Clone variation with respect to NM_003679.3 786 g=>a;1354 c=>t >OriGene 5' read for NM_003679 unedited
NAACGTTCAAATTTGTAAACGACTCACTATAGGCGGCCGCGAATTCGCACGAGGCACTCA GTGACAGAAGCAACAATAATTGTGAAAAAACTTCAGCAGTTATGGACTCATCTGTCATTC AAAGGAAAAAAGTAGCTGTCATTGGTGGTGGCTTGGTTGGCTCATTACAAGCATGCTTTC TTGCAAAGAGGAATTTCCAGATTGATGTATATGAAGCTAGGGAAGATACTCGAGTGGCTA CCTTCACACGTGGAAGAAGCATTAACTTAGCCCTTTCTCATAGAGGACGACAAGCCTTGA AAGCTGTTGGCCTGGAAGATCAGATTGTATCCCAAGGTATTCCCATGAGAGCAAGAATGA TCCACTCTCTTTCAGGAAAAAAGTCTGCAATTCCCTATGGGACAAAGTCTCAGTATATTC TTTCTGTAAGCAGAGAAAATCTAAACAAGGATCTATTGACTGCTGCTGAGAAATACCCCA ATGTGAAAATGCACTTTAACCACAGGCTGTTGAAATGTAATCCAGAGGAAGGAATGATCA CAGTGCTTGGATCTGACAAAGTTCCCAAAGATGTCACTTGTGACCTCATTGTAGGATGTG ATGGAGCCTATTCAACTGTCAGATCTCACCTGATGAAGAAACCTCGCTTTGATTACAGTC AGCAGTACATTCCTCATGGGTACATGGAGTTGACTATTCCCACCTAGAACGAGATTATGC CATGGGACCTAATTATCTGCATATTTGGCCTAGAAATACCTTTATGATGATTGCACTTNC CTACATGAAACAATCATTCACATGTACTTTGTTCATGCCCTTTTGAAGAGTTTGAAAAAC TCTNACCAGTAATGATGTGGTAGATTTNCTTCCAGAATACTTTCCAGATGCCATCCCNTC TATTGNAGAGAAACTNNCTAGTGCAGAC >OriGene 3' read for NM_003679 unedited
GCGGCCCGCAATCTAGNATCGAGTTTTTTTTTTTTTTTTTTTGCCCAATTTTTATTTCTT ATATGACTCTAGTGTTTCATCTTCATAATTAATCATGTTTGAAGGATTTCTGAGTGACTC AGCAGCCTGTTAAAGAAGGATGAACCAAAGAAAACATTTCACTAAATGTGCTTTTAAAAA TCAAGTGTATTGCTGGTTCTGCTGCAGTATGTAGTCGAAGAATAAATTAGTAAATTGCTT CTGAGGGTCTGAAATTGAATAAAGTAATGGCTTTGTATTTCTATAAAAGTTGTCTCCCCT TGTTTCCTTTCCATTCTGGCACATGTAGACATTTAATTTATGAATAAAACCCTTTCCTGT CCTTCACTTAGTATGATATTAATAGCCTTTTTCTTATCTTTAGAGGGTAACTCTGGGCTG GCAGCGGTGGCTCACAACTCTAATCCCTGTACTTTGGGAGGCTGAGGTGGGCAGATCACA TGAGGCCAGGAGTTTGAGACTGGCCTGNGCAGCATGGCAAGACCCGGTCTCTACTGAAAA ATACCATGGTAGCCCCAGCTATTTGNGAGGCTGAAGTGGGAGGATTGCTTGAGCCCAGGA GGCAGAGGTTGCAGTGAACCCAGATCTCACCACTGCACTCCAGCCTGGTCAACAGAGTGA GACCTGATCTCTAATACATAANTAAATAGAGATAGATAGATAGATAGATAGATAGATAGA TAGATAGATGATCGATAGATAGATAGATGATAGATAGATAGACGATAAACCAGATGATGA TACTACCTATATTTGAAGGTGGGAAATAAAATGAGGTCATTCTGAAGTCTCCTGGACTCC CCTGGAATCCTTATTTCCATTTCTGGTTTTAACTAGAAAGTCTGAACCCTGGGGNTATGA AGTTTCCATCACNGTATGGAAAGGGCAGTTACATGCTAGTAAGTTGGGATTTTAGCCCTA GGGTG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_003679 |
| Insert Size | 1461 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_003679.2, NP_003670.1 |
| RefSeq Size | 4992 bp |
| RefSeq ORF | 1461 bp |
| Locus ID | 8564 |
| UniProt ID | O15229 |
| Domains | Monooxygenase |
| Protein Families | Druggable Genome |
| Protein Pathways | Metabolic pathways, Tryptophan metabolism |
| Gene Summary | This gene encodes a mitochondrion outer membrane protein that catalyzes the hydroxylation of L-tryptophan metabolite, L-kynurenine, to form L-3-hydroxykynurenine. Studies in yeast identified this gene as a therapeutic target for Huntington disease. [provided by RefSeq, Oct 2011] |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
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Prognostic significance of kynurenine 3-monooxygenase and effects on proliferation, migration, and invasion of human hepatocellular carcinoma
,Jin, H;Zhang, Y;You, H;Tao, X;Wang, C;Jin, G;Wang, N;Ruan, H;Gu, D;Huo, X;Cong, W;Qin, W;,
Sci Rep
,PubMed ID 26099564
[KMO]
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Development of LC/MS/MS, High-Throughput Enzymatic and Cellular Assays for the Characterization of Compounds That Inhibit Kynurenine Monooxygenase (KMO)
,Dirk Winkler, Maria Beconi, Leticia M. Toledo-Sherman, Michael Prime, Andreas Ebneth, Celia Dominguez, and Ignacio Muñoz-Sanjuan,
J Biomol Screen, May 2013; 10.1177/1087057113489731.
,PubMed ID 23690293
[KMO]
|
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC222594 | KMO (Myc-DDK-tagged)-Human kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) (KMO) |
CNY 3,656.00 |
|
| RC222594L1 | Lenti ORF clone of Human kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) (KMO), Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC222594L2 | Lenti ORF clone of Human kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) (KMO), mGFP tagged |
CNY 6,180.00 |
|
| RC222594L3 | Lenti ORF clone of Human kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) (KMO), Myc-DDK-tagged |
CNY 6,180.00 |
|
| RC222594L4 | Lenti ORF clone of Human kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) (KMO), mGFP tagged |
CNY 6,180.00 |
|
| RG222594 | KMO (tGFP-tagged) - Human kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) (KMO) |
CNY 5,256.00 |
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