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IKK gamma (IKBKG) (NM_003639) Human Untagged Clone
CAT＃: SC117828
IKBKG (untagged)-Human inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma (IKBKG), transcript variant 3
CNY 3,656.00
| Cited in 1 publication. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | AMCBX1; EDAID1; FIP-3; FIP3; Fip3p; IKK-gamma; IKKAP1; IKKG; IMD33; IP; IP1; IP2; IPD2; NEMO; ZC2HC9 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_003639 edited
GAATTCGGCACGAGCGGGGCCCTACCAGCGTTCACAGTCCGCCGCTCCCACCCTTCTCAC GTCTGACGGACTCTGCTGACAGCCCTTGCCCTGTTGGATGAATAGGCACCTCTGGAAGAG CCAACTGTGTGAGATGGTGCAGCCCAGTGGTGGCCCGGCAGCAGATCAGGACGTACTGGG CGAAGAGTCTCCTCTGGGGAAGCCAGCCATGCTGCACCTGCCTTCAGAACAGGGCGCTCC TGAGACCCTCCAGCGCTGCCTGGAGGAGAATCAAGAGCTCCGAGATGCCATCCGGCAGAG CAACCAGATTCTGCGGGAGCGCTGCGAGGAGCTTCTGCATTTCCAAGCCAGCCAGAGGGA GGAGAAGGAGTTCCTCATGTGCAAGTTCCAGGAGGCCAGGAAACTGGTGGAGAGACTCGG CCTGGAGAAGCTCGATCTGAAGAGGCAGAAGGAGCAGGCTCTGCGGGAGGTGGAGCACCT GAAGAGATGCCAGCAGCAGATGGCTGAGGACAAGGCCTCTGTGAAAGCCCAGGTGACGTC CTTGCTCGGGGAGCTGCAGGAGAGCCAGAGTCGCTTGGAGGCTGCCACTAAGGAATGCCA GGCTCTGGAGGGTCGGGCCCGGGCGGCCAGCGAGCAGGCGCGGCAGCTGGAGAGTGAGCG CGAGGCGCTGCAGCAGCAGCACAGCGTGCAGGTGGACCAGCTGCGCATGCAGGGCCAGAG CGTGGAGGCCGCGCTCCGCATGGAGCGCCAGGCCGCCTCGGAGGAGAAGAGGAAGCTGGC CCAGTTGCAGGTGGCCTATCACCAGCTCTTCCAAGAATACGACAACCACATCAAGAGCAG CGTGGTGGGCAGTGAGCGGAAGCGAGGAATGCAGCTGGAAGATCTCAAACAGCAGCTCCA GCAGGCCGAGGAGGCCCTGGTGGCCAAACAGGAGGTGATCGATAAGCTGAAGGAGGAGGC CGAGCAGCACAAGATTGTGATGGAGACCGTTCCGGTGCTGAAGGCCCAGGCGGATATCTA CAAGGCGGACTTCCAGGCTGAGAGGCAGGCCCGGGAGAAGCTGGCCGAGAAGAAGGAGCT CCTGCAGGAGCAGCTGGAGCAGCTGCAGAGGGAGTACAGCAAACTGAAGGCCAGCTGTCA GGAGTCGGCCAGGATCGAGGACATGAGGAAGCGGCATGTCGAGGTCTCCCAGGCCCCCTT GCCCCCCGCCCCTGCCTACCTCTCCTCTCCCCTGGCCCTGCCCAGCCAGAGGAGGAGCCC CCCCGAGGAGCCACCTGACTTCTGCTGTCCCAAGTGCCAGTATCAGGCCCCTGATATGGA CACCCTGCAGATACATGTCATGGAGTGCATTGAGTAGGGCCGGCCAGTGCAAGGCCACTG CCTGCCGAGGACGTGCCCGGGACCGTGCAGTCTGCGCTTTCCTCTCCCGCCTGCCTAGCC CAGGATGAAGGGCTGGGTGGCCACAACTGGGATGCCACCTGGAGCCCCACCCAGGAGCTG GCCGCGGCACCTTACGCTTCAGCTGTTGATCCGCTGGTCCCCTCTTTTGGGGTAGATGCG GCCCCGATCAGGCCTGACTCGCTGCTCTTTTTGTTCCCTTCTGTCTGCTCGAACCACTTG CCTCGGGCTAATCCCTCCCTCTTCCTCCACCCGGCACTGGGGAAGTCAAGAATGGGGCCT GGGGCTCTCAGGGAGAACTGCTTCCCCTGGCAGAGCTGGGTGGCAGCTCTTCCTCCCACC GGACACCGACCCGCCCGCTGCTGTGCCCTGGGAGTGCTGCCCTCTTACCATGCACACGGG TGCTCTCCTTTTGGGCTGCATGCTATTCCATTTTGCAGCCAGACCGATGTGTATTTAACC AGTCACTATTGATGGACATTTGGGTTGTTTCCCATCTTTTTGTTACCATAAATAATGGCA TAGTAAAAAAAAAAAAAAAAAACTCGAC >OriGene 5' read for NM_003639 unedited
TCAGATTTTGTAATACGACTTCACTATAGGGCGGCCGCGAATTCGCACGAGCGGGNGCCC TACCAGCGTTCACAGTCCGCCGCTCCCACCCTTCTCACGTCTGACGGACTCTGCTGACAG CCCTTGCCCTGTTGGATGAATAGGCACCTCTGGAAGAGCCAACTGTGTGAGATGGTGCAG CCCAGTGGTGGCCCGGCAGCAGATCAGGACGTACTGGGCGAAGAGTCTCCTCTGGGGAAG CCAGCCATGCTGCACCTGCCTTCAGAACAGGGCGCTCCTGAGACCCTCCAGCGCTGCCTG GAGGAGAATCAAGAGCTCCGAGATGCCATCCGGCAGAGCAACCAGATTCTGCGGGAGCGC TGCGAGGAGCTTCTGCATTTCCAAGCCAGCCAGAGGGAGGAGAAGGAGTTCCTCATGTGC AAGTTCCAGGAGGCCAGGAAACTGGTGGAGAGACTCGGCCTGGAGAAGCTCGATCTGAAG AGGCAGAAGGAGCAGGCTCTGCGGGAGGTGGAGCACCTGAAGAGATGCCAGCAGCAGATG GCTGAGGACAAGGCCTCTGTGAAAGCCCAGGTGACGTCCTTGCTCGGGGAGCTGCAGGAG AGCCAGAGTCGCTTGGAGGCTGCCACTAAGGAATGCCAGGCTCTGGAGGGTCAGGCCCGG GCGGCCAGCGAGCAGGCGCGGCAGCTGGAGAGTGAGCGCGAGGCGCTGCAGCAGCAGCAC AGCGTGCAGGTGGACCAGCTGCGCATGCAGGGCCAGAGCGTGGAGGCCGCGCTCCGCATG GAGCGCCAGCCCCGCCTCGAGGAGAAAGAGGAGCTGGGCCAGTTGCAGGTGGCCTATCAC CAGCTCTTTCCANNGATACGACACCACATCAGAGCANCGTGGTGGGCAGTGAGCGGAACC GAGNATGCANCTGGGAGATCTCAACAGCAGCTCAGCAGACCGAGGAGGCCTGGTGGCCAA CAGNAGTGATCGATAGCTGAAG >OriGene 3' read for NM_003639 unedited
CATAAGCCTCATGGCGATCGGCATCTTCCCATGACCAGGAAAGCACTGGGGAGGGTCACA GGGCTGCCACCCGGGTTCTGTTCAGGAAAAGCTATGACCGCGGCCGCAATCTAAAGTCGA GTTTTTTTTTTTTTTTTTTACTATGCCATTATTTATGGTAACAAAAAATGGGAAACAACC CAAATGTCCATCAATAGTGACTGGTTAAATACACATCGGTCTGGCTGCAAAATGGAATAG CATGCAGCCCAAAAGGAGAGCACCCGTGTGCATGGTAAGAGGGCAGCACTCCCAGGGCAC AGCAGCGGGCGGGTCGGTGTCCGGTGGGAAGAATATCTGCCACCCAGCTCTGCCAGGGGA AGCAGTTCTCCCTGAGAGCCCCAGGCCCCATTCTTGACTTCCCCAGTGCCGGGTGGAAGA AGAGGGAGGGATTAGCCCGAGGCATGTGGTTCGAGCATACAGAAGGGAACAAAAAGAGCA GCGAGTCAGGCCTGATCGGGGCCGCCTCTACCCCAAAAGAGGGGACCAGCGGATCAACAG CTGAAGCGTAAGGTGCCGCGGCCAGCTCCTGGGTGGGGCTCCAGGTGGCATCCCAGTTGT GGCCACCCAGCCCTTCATCCTGGGCTAGGCAGGCGGGAGAGGAAAGCGCAAACTGCACGG TCCCGGGCACGTCCTCGGCAGGCAGTGGCCTTGCACTGGCCGGCCCTACTCAATGCACTC CATGACATGTTTCTGCAGGGTGTCCATATCAGGGGCCTGATACTGGCACTTGGGACAACA AATGTCATGTGGCTCCTCGGGGGGGCTCCTCCTCTGGCTGGCCNNGGGCCAGGGGAAAAG AAAATGTAACCCGGGGCCGGGGGGCAAAGGGGCCCTGGAAAACCTTNNATTGCCCCTTTC CCATGTCCCTGATA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_003639 |
| Insert Size | 2000 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_003639.2, NP_003630.1 |
| RefSeq Size | 2121 bp |
| RefSeq ORF | 1260 bp |
| Locus ID | 8517 |
| UniProt ID | Q9Y6K9 |
| Domains | zf-C2H2 |
| Protein Families | Druggable Genome, Transcription Factors |
| Protein Pathways | Acute myeloid leukemia, Adipocytokine signaling pathway, Apoptosis, B cell receptor signaling pathway, Chemokine signaling pathway, Chronic myeloid leukemia, Cytosolic DNA-sensing pathway, Epithelial cell signaling in Helicobacter pylori infection, MAPK signaling pathway, NOD-like receptor signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prostate cancer, RIG-I-like receptor signaling pathway, Small cell lung cancer, T cell receptor signaling pathway, Toll-like receptor signaling pathway |
| Gene Summary | This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome. [provided by RefSeq, Mar 2016] Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 3 and 5 encode the same isoform (a). |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Biallelic hypomorphic mutations in a linear deubiquitinase define otulipenia, an early-onset autoinflammatory disease
,Zhou, Q;Yu, X;Demirkaya, E;Deuitch, N;Stone, D;Tsai, WL;Kuehn, HS;Wang, H;Yang, D;Park, YH;Ombrello, AK;Blake, M;Romeo, T;Remmers, EF;Chae, JJ;Mullikin, JC;Güzel, F;Milner, JD;Boehm, M;Rosenzweig, SD;Gadina, M;Welch, SB;Özen, S;Topaloglu, R;Abinun, M;Kastner, DL;Aksentijevich, I;,
Proc. Natl. Acad. Sci. U.S.A.
,PubMed ID 27559085
[IKBKG]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC201743 | IKBKG (Myc-DDK-tagged)-Human inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma (IKBKG), transcript variant 3 |
CNY 3,656.00 |
|
| RC201743L1 | Lenti ORF clone of Human inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma (IKBKG), transcript variant 3, Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC201743L2 | Lenti ORF clone of Human inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma (IKBKG), transcript variant 3, mGFP tagged |
CNY 5,890.00 |
|
| RC201743L3 | Lenti ORF clone of Human inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma (IKBKG), transcript variant 3, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC201743L4 | Lenti ORF clone of Human inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma (IKBKG), transcript variant 3, mGFP tagged |
CNY 5,890.00 |
|
| RG201743 | IKBKG (tGFP-tagged) - Human inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma (IKBKG), transcript variant 3 |
CNY 4,370.00 |
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