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PARG (NM_003631) Human Untagged Clone
CAT＃: SC117822
PARG (untagged)-Human poly (ADP-ribose) glycohydrolase (PARG)
CNY 7,152.00
| Cited in 3 publications. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | PARG99 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC117822 sequence for NM_003631 edited (data generated by NextGen Sequencing)
ATGAATGCGGGCCCCGGCTGTGAACCCTGCACCAAGCGACCCCGCTGGGGCGCCGCTACA ACTTCGCCGGCTGCTTCGGACGCCCGGAGCTTTCCCAGCAGGCAGAGGCGCGTCCTCGAC CCCAAGGACGCTCACGTGCAGTTCAGGGTCCCACCGTCCTCGCCAGCCTGCGTCCCAGGG CGGGCGGGACAGCACAGAGGCAGCGCCACCTCGCTTGTTTTCAAACAAAAGACTATTACC AGTTGGATGGACACTAAAGGAATCAAGACAGCGGAATCAGAAAGTTTGGATAGTAAAGAA AACAACAATACAAGAATAGAATCCATGATGAGTTCTGTACAAAAAGATAACTTTTACCAA CATAATGTAGAAAAATTAGAAAATGTTTCTCAGCTAAGTCTTGATAAGTCACCCACTGAA AAAAGTACACAGTATTTGAACCAGCATCAGACTGCAGCAATGTGTAAGTGGCAAAATGAA GGGAAACACACGGAGCAGCTTTTGGAAAGTGAACCTCAAACAGTAACCCTGGTACCAGAG CAGTTTAGTAATGCTAACATTGATCGGTCACCTCAAAATGATGATCACAGTGACACAGAT AGTGAAGAGAATAGAGACAATCAACAGTTTCTCACAACTGTAAAGCTTGCAAATGCAAAG CAGACTACAGAAGATGAACAGGCCAGAGAAGCCAAAAGCCACCAGAAGTGCAGCAAGTCT TGCGATCCTGGGGAAGACTGTGCAAGTTGTCAGCAAGATGAGATAGATGTGGTGCCAGAG AGTCCATTGTCAGATGTTGGCTCTGAGGATGTTGGTACTGGGCCAAAAAATGACAACAAA TTGACTAGACAAGAAAGTTGCCTAGGAAATTCTCCTCCATTTGAGAAGGAAAGTGAACCC GAGTCACCGATGGATGTGGATAATTCTAAAAATAGTTGTCAAGACTCAGAAGCAGATGAG GAGACAAGTCCAGGTTTTGATGAACAAGAAGATGGTAGTTCCTCCCAAACAGCAAATAAA CCTTCAAGGTTCCAAGCAAGAGACGCTGACATTGAATTTAGGAAACGGTACTCTACTAAG GGCGGTGAAGTTAGATTACATTTCCAATTTGAAGGAGGAGAGAGTCGCACTGGAATGAAT GATTTAAATGCTAAACTACCTGGAAATATTTCTAGCCTGAATGTAGAATGCAGAAATTCT AAGCAACATGGAAAAAAGGATTCTAAAATCACAGATCATTTCATGAGACTGCCCAAAGCA GAGGACAGAAGAAAAGAACAGTGGGAAACCAAACATCAAAGAACAGAAAGGAAGATCCCT AAATACGTTCCACCTCACCTTTCTCCAGATAAGAAGTGGCTTGGAACTCCCATTGAGGAG ATGAGAAGAATGCCTCGGTGTGGGATCCGGCTGCCTCTCTTGAGACCATCTGCCAATCAC ACAGTAACTATTCGGGTAGATCTTTTGCGAGCAGGAGAAGTTCCTAAACCTTTTCCAACA CATTATAAAGATTTGTGGGATAACAAGCATGTTAAAATGCCTTGTTCAGAACAAAATTTG TACCCAGTGGAAGATGAGAATGGTGAGCGAACTGCGGGGAGCCGGTGGGAGCTCATTCAG ACTGCACTTCTCAACAAATTTACACGACCCCAAAACTTGAAGGATGCTATTCTGAAATAC AATGTGGCATATTCTAAGAAATGGGACTTTACAGCTTTGATCGATTTCTGGGATAAGGTA CTTGAAGAAGCAGAAGCTCAACATTTATATCAGTCCATCTTGCCTGATATGGTGAAAATT GCACTCTGTCTGCCAAATATTTGCACCCAGCCAATACCACTCCTGAAACAGAAGATGAAT CATTCCATCACAATGTCGCAGGAACAGATTGCCAGTCTTTTAGCTAATGCTTTCTTCTGC ACATTTCCACGACGAAATGCTAAGATGAAATCGGAGTATTCTAGTTACCCAGACATTAAC TTCAATCGATTGTTTGAGGGACGTTCATCAAGGAAACCGGAGAAACTTAAAACGCTCTTC TGCTACTTTAGAAGAGTCACAGAGAAAAAACCTACTGGGTTGGTGACATTTACAAGACAG AGTCTTGAAGATTTTCCAGAATGGGAAAGATGTGAAAAACCCTTGACACGATTGCATGTC ACTTACGAAGGTACCATAGAAGAAAATGGCCAAGGCATGCTACAGGTGGATTTTGCAAAT CGTTTTGTTGGAGGTGGTGTAACCAGTGCAGGACTTGTGCAAGAAGAAATCCGCTTTTTA ATCAATCCTGAGTTGATTATTTCACGGCTCTTCACTGAGGTGCTGGATCACAATGAATGT CTAATTATCACAGGTACTGAGCAGTACAGTGAATACACAGGCTATGCTGAGACATATCGT TGGTCCCGGAGCCACGAAGATGGGAGTGAAAGGGACGACTGGCAGCGGCGCTGCACTGAG ATCGTTGCCATCGATGCTCTTCACTTCAGACGCTACCTCGATCAGTTTGTGCCTGAGAAA ATGAGACGCGAGCTGAACAAGGCTTACTGTGGATTTCTCCGTCCTGGAGTTTCTTCAGAG AATCTTTCTGCAGTGGCCACAGGAAACTGGGGCTGTGGTGCCTTTGGGGGTGATGCCAGG TTAAAAGCCTTAATACAGATATTGGCAGCTGCTGCAGCTGAGCGAGATGTGGTTTATTTC ACCTTTGGGGACTCAGAATTGATGAGAGACATTTACAGCATGCACATTTTCCTTACTGAA AGGAAACTCACTGTTGGAGATGTGTATAAGCTGTTGCTACGATACTACAATGAAGAATGC AGAAACTGTTCCACCCCTGGACCAGACATCAAGCTTTATCCATTCATATACCATGCTGTC GAGTCCTGTGCAGAGACCGCTGACCATTCAGGGCAAAGGACAGGGACCTGA Clone variation with respect to NM_003631.2 669 g=>a >OriGene 5' read for NM_003631 unedited
TGTATACGACTCACTTATAGGGCGGCCGCGATTTGGCACGAGGGGCAGGTGGGGTGCCAG TGGAAGAGGGAAGGCAGGCGAGTGTTTACGGCCTGACTTGGGAGGCCGGCGGATCAGCAA TTGCAGAAGCAGGCAGCGGCAGAGAGGGAATGGTGCAGGCAGGCGCTGAGAAGGAGGCGC AGTCCATCTCTCTCAGGGTTAGTGAATGAGGCTCTCCGCCCGGGCCGGCCCGGGGACAGT GCGCTGCTGGTCCCAGCATGAATGCGGGCCCCGGCTGTGAACCCTGCACCAAGCGACCCC GCTGGGGCGCCGCTACAACTTCGCCGGCTGCTTCGGACGCCCGGAGCTTTCCCAGCAGGC AGAGGCGCGTCCTCGACCCCAAGGACGCTCACGTGCAGTTCAGGGTCCCACCGTCCTCGC CAGCCTGCGTCCCAGGGCGGGCGGGACAGCACAGAGGCAGCGCCACCTCGCTTGTTTTCA AACAAAAGACTATTACCAGTTGGATGGACACTAAAGGAATCAAGACAGCGGAATCAGAAA GTTTGGATAGTAAAGAAAACAACAATACAAGAATAGAATCCATGATGAGTTCTGTACAAA AAGATAACTTTTACCAACATAATGTAGAAAAATTAGAAAATGTTTCTCAGCTAAGTCTTG ATAAGTCACCCACTGGAAAAAGTACACAGTATTTGAACCAGCATCAGACTGCAGNCATGG TGTAAGTGGCANAATGAAGGGAAACACACGGAGCAGCTTTGGNAAAGTGAACCTCAACAG TAACCCTGGTACCAGAGCAGNTTAGTAATGCTACCATTGATCGGNCACCTCAAATGATGA TCCCAGTGCACAGATAGTGAAGAGATAGAGACATCACAGTTTCTACACTGTAAAGCTTGC AATGCAAGCAACTACAGAGATGACAGCCANAAAN >OriGene 3' read for NM_003631 unedited
NNCCTACTTGNAAGCGGCCGCATTCTANGATCGAGTTTTTTTTTTTTTTTTTTTTTTTTT TTTTTTTTTTTTTCCCACCAGTCCAATTTTATTTAAATTTTATGGGCTCACATATAGACA CACTTAAAGAGCATACGTTTATTTATACATATTTAAAATATAGATGATTTGGGAGTTTCT GACAAAGGGATTTATTAAGGAAAATTCATTCACTATATAACCTTTGAATACCAAAAAAAC TTCAATATGTACAAATCAGCATGAAGTTCCCAGTTCTCAAACTTTGGTTATATGAATATG CCTCAAGCCCCAAAAAAAAAACATTAGCCCTAATTTAAAAAGAAAAAAGTACCAAGAAAC AAAAAAAATCTCAAATTTTCTTGAATCGGTTTTTTTTACACCACATCAGGAAAACCTCCT TTTATTCCCACATTTCCTTTCATCTAAGGCAGTCTCCAAAACTGGTATAAAAAAATCCTG TCCAGAGGAAAAAAGACAGACAAACCCTTACAGACAAAAATGATCCCTCAAAGCACAATT TCTGGAAATTATTCTATCTTAAATAAAGAAACTATTTTAACCTAGGAGGTTCGCTTTATG CCCCACATATGACAAAACCCCCAATTATTAATCCCCAGAATTCAAAAACTTTAACATGGC CGCCATTTTAACAGTCGAGTGGAAGGCTCCAGGGAAATTTTTATCACAATCCGTTAAAGA GATCCCTGGATTTCAACCTGCTTCCTGGCACCCCTGGTATCTGCGGCGTTGCCAAAGCCC CCGTTATAAATTATGGGCCAGACAAAAAAAACCCGACGGGCTTGAACACACCTTTCATGG GCATCTCACAAATTATCGCGGGACCCAATGAATCACCTCTCAGAAAGGGAAACCTGCATC AAAACCAAATTCAAN |
| Restriction Sites | ECoRI-NOT |
| ACCN | NM_003631 |
| Insert Size | 4420 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_003631.2, NP_003622.2 |
| RefSeq Size | 4276 bp |
| RefSeq ORF | 2931 bp |
| Locus ID | 8505 |
| UniProt ID | Q86W56 |
| Domains | PARG |
| Gene Summary | Poly(ADP-ribose) glycohydrolase (PARG) is the major enzyme responsible for the catabolism of poly(ADP-ribose), a reversible covalent-modifier of chromosomal proteins. The protein is found in many tissues and may be subject to proteolysis generating smaller, active products. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2015] Transcript Variant: This variant (1) encodes the longest isoform (a). |
Citations (3)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Non-NAD-like PARP-1 inhibitors in prostate cancer treatment
,Karpova, Y;Wu, C;Divan, A;McDonnell, ME;Hewlett, E;Makhov, P;Gordon, J;Ye, M;Reitz, AB;Childers, WE;Skorski, T;Kolenko, V;Tulin, AV;,
Biochem. Pharmacol.
,PubMed ID 30880062
[PARG]
|
|
Comparative inhibitory profile and distribution of bacterial PARPs, using Clostridioides difficile CD160 PARP as a model
,García-Saura, AG;Zapata-Pérez, R;Hidalgo, JF;Sánchez-Ferrer, Á;,
Sci Rep
,PubMed ID 29795234
[PARG]
|
|
Cooperative Role of NF-{kappa}B and Poly(ADP-ribose) Polymerase 1 (PARP-1) in the TNF-induced Inhibition of PHEX Expression in Osteoblasts
,Pawel M. Majewski, Robert D. Thurston, Rajalakshmy Ramalingam, Pawel R. Kiela, and Fayez K. Ghishan,
J. Biol. Chem., Nov 2010; 285: 34828 - 34838.
[PARG]
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Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC208530 | PARG (Myc-DDK-tagged)-Human poly (ADP-ribose) glycohydrolase (PARG) |
CNY 7,152.00 |
|
| RC208530L1 | Lenti ORF clone of Human poly (ADP-ribose) glycohydrolase (PARG), Myc-DDK-tagged |
CNY 9,552.00 |
|
| RC208530L2 | Lenti ORF clone of Human poly (ADP-ribose) glycohydrolase (PARG), mGFP tagged |
CNY 5,890.00 |
|
| RC208530L3 | Lenti ORF clone of Human poly (ADP-ribose) glycohydrolase (PARG), Myc-DDK-tagged |
CNY 9,552.00 |
|
| RC208530L4 | Lenti ORF clone of Human poly (ADP-ribose) glycohydrolase (PARG), mGFP tagged |
CNY 9,552.00 |
|
| RG208530 | PARG (tGFP-tagged) - Human poly (ADP-ribose) glycohydrolase (PARG) |
CNY 8,752.00 |
|
| SC323845 | PARG (untagged)-Human poly (ADP-ribose) glycohydrolase (PARG) |
CNY 7,152.00 |
