NUMB (NM_003744) Human Untagged Clone

CAT#: SC117802

NUMB (untagged)-Human numb homolog (Drosophila) (NUMB), transcript variant 3



  "NM_003744" in other vectors (7)

CNY 1,200.00


货期*
现货

规格
    • 10 ug

Product images

经常一起买 (4)
NUMB mouse monoclonal antibody, clone OTI4F3 (formerly 4F3)
    • 100 ul

CNY 1,999.00
CNY 2,700.00


TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Synonyms C14orf41; c14_5527; S171
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>NCBI ORF sequence for NM_003744, the custom clone sequence may differ by one or more nucleotides


ATGAACAAATTACGGCAAAGTTTTAGGAGAAAGAAGGATGTTTATGTTCCAGAGGCCAGTCGTCCACATC
AGTGGCAGACAGATGAAGAAGGCGTTCGCACCGGAAAATGTAGCTTCCCGGTTAAGTACCTTGGCCATGT
AGAAGTTGATGAATCAAGAGGAATGCACATCTGTGAAGATGCTGTAAAAAGATTGAAAGCTACTGGAAAG
AAAGCAGTTAAAGCAGTTCTGTGGGTCTCAGCAGATGGACTCAGAGTTGTGGATGAAAAAACTAAGGACC
TCATAGTTGACCAGACGATAGAGAAAGTTTCTTTCTGTGCCCCAGACAGGAACTTTGATAGAGCCTTTTC
TTACATATGCCGTGATGGCACCACTCGTCGCTGGATCTGTCACTGCTTCATGGCTGTCAAGGACACAGGT
GAAAGGTTGAGCCATGCAGTAGGCTGTGCTTTTGCAGCCTGTTTAGAGCGCAAGCAGAAGCGGGAGAAGG
AATGTGGAGTGACTGCTACTTTTGATGCTAGTCGGACCACTTTTACAAGAGAAGGATCATTCCGTGTCAC
AACAGCCACTGAACAAGCAGAAAGAGAGGAGATCATGAAACAAATGCAAGATGCCAAGAAAGCTGAAACA
GATAAGATAGTCGTTGGTTCATCAGTTGCCCCTGGCAACACTGCCCCATCCCCATCCTCTCCCACCTCTC
CTACTTCTGATGCCACGACCTCTCTGGAGATGAACAATCCTCATGCCATCCCACGCCGGCATGCTCCAAT
TGAACAGCTTGCTCGCCAAGGCTCTTTCCGAGGTTTTCCTGCTCTTAGCCAGAAGATGTCACCCTTTAAA
CGCCAACTATCCCTACGCATCAATGAGTTGCCTTCCACTATGCAGAGGAAGACTGATTTCCCCATTAAAA
ATGCAGTGCCAGAAGTAGAAGGGGAGGCAGAGAGCATCAGCTCCCTGTGCTCACAGATCACCAATGCCTT
CAGCACACCTGAGGACCCCTTCTCATCTGCTCCGATGACCAAACCAGTGACAGTGGTGGCACCACAATCT
CCTACCTTCCAAGCTAATGGCACTGACTCAGCCTTCCATGTGCTTGCTAAGCCAGCCCATACTGCTCTAG
CACCCGTAGCAATGCCTGTGCGTGAAACCAACCCTTGGGCCCATGCCCCTGATGCTGCTAACAAGGAAAT
TGCAGCCACATGTTCGGGGACCGAGTGGGGTCAATCTTCTGGTGCTGCCTCTCCAGGTCTCTTCCAGGCC
GGTCATAGACGTACTCCCTCTGAGGCCGACCGATGGTTAGAAGAGGTGTCTAAGAGCGTCCGGGCTCAGC
AGCCCCAGGCCTCAGCTGCTCCTCTGCAGCCAGTTCTCCAGCCTCCTCCACCCACTGCCATCTCCCAGCC
AGCATCACCTTTCCAAGGGAATGCATTCCTCACCTCTCAGCCTGTGCCAGTGGGTGTGGTCCCAGCCCTG
CAACCAGCCTTTGTCCCTGCCCAGTCCTATCCTGTGGCCAATGGAATGCCCTATCCAGCCCCTAATGTGC
CTGTGGTGGGCATCACTCCCTCCCAGATGGTGGCCAACGTATTTGGCACTGCAGGCCACCCTCAGGCTGC
CCATCCCCATCAGTCACCCAGCCTGGTCAGGCAGCAGACATTCCCTCACTACGAGGCAAGCAGTGCTACC
ACCAGTCCCTTCTTTAAGCCTCCTGCTCAGCACCTCAACGGTTCTGCAGCTTTCAATGGTGTAGATGATG
GCAGGTTGGCCTCAGCAGACAGGCATACAGAGGTTCCTACAGGCACCTGCCCAGTGGATCCTTTTGAAGC
CCAGTGGGCTGCATTAGAAAATAAGTCCAAGCAGCGTACTAATCCCTCCCCTACCAACCCTTTCTCCAGT
GACTTACAGAAGACGTTTGAAATTGAACTTTAA


>OriGene 5' read for NM_003744 unedited
TACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGATTACAGGTGTGAGCTACCAC
AACCAGCTAGTTTCTGTATTGTGGATGAGCCATAGCAACAGCGAGGGGTTTCTGACATCA
GTCAGCTGCCGTGGTTTAATGCATTTGAGCCATATCTAGACAGTGCTTCAGTGTGGCTGA
CACAGCAGCATGGTCTTGACAAGTTTTCTTCATCCTACCACAAAATCCCAGTTGGTAATA
GAGACTTTACTCCTACCTATCAAAACCACAAAATGTCCCATTAGGGGGGGACATGTTGTA
CATGTTAGGATCATTCAAATAACCAAGATTATAAGGTGAGGAAAGATGCCCCTAACTGAT
TCTTTTGTCTCTCATCTTGTTGGTTCCAGGGACCGAGTGGGGTCAATCTTCTGGTGCTGC
CTCTCCAGGTCTCTTCCAGGCCGGTCATAGACGTACTCCCTCTGAGGCCGACCGATGGTT
AGAAGAGGTGTCTAAGAGCGTCCGGGCTCAGCAGCCCCAGGCCTCAGCTGCTCCTCTGCA
GCCAGTTCTCCAGCCTCCTCCACCCACTGCCATCTCCCAGCCAGCATCACCTTTCCAAGG
GAATGCATTCCTCACCTCTCAGCCTGTGCCAGTGGGTGTGGTCCCAGCCCTGCACCAGCC
TTTGTCCCTGCCCAGTCCTATCCTGTGGCCAATGGAATGCCCTATCCAGCCCCTAATGTG
CCTGTGGTGGGCATCACTCCCTCCCAGATGGTGGCCAACGTATTTGGCACTGCAGGCCAC
CCTCANGCTGCCCCATCCCATCAGTCACCCAGCCTGGTCAGGCAGCAGACATTTCCTTCA
CTACGAGCAGCAGTGCTACCACCAGTCCTTTCTTTAAAGCTCTGCTCACACCTCAACGGT
TCTGCAGCTTTCATGGTGTAAAGATGGCAGGTTGGCTCACCGACAGCATACAGAGGTTCT
ACNG
>OriGene 3' read for NM_003744 unedited
GGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTCTACCATGAACATTTATTTTTG
TTAAAGCAGATTATAAATTTTCATCAGTACAAATATATATAACTTACATTTGATTGTAAG
GCCAACGTTCAAAAGTAAAAATGAGATGAGCTCTCTTATTGTTATCCGAGGTCAAGAGGC
TGCAACTGTCAAGGGGATGTTCTCACCAAAAGGGGGTTTGGGGGAAGAGGACACACACAA
AGCTAATAAAACCAGAATCCCCATCCCCACAAAACTCATGGGAACAAAATTTAAAGGATA
AAACAAAACCCACCAAGACCCATATTACAAACCAATATGGTAACCTGTGTTCCCTTCTAT
GGTATGATTATGTCATGTTACCTTAGTGTTAAAAGATTAACATAAGGAAACTGCAGCAAT
ATATAAAAGATATATTCTCTATAGAGCATATTTCGATTGATTCCATTAAAATAATGACAT
TAGAATTCCATCATAGGTTTAAAACCAGGACAATACTGCTTTTCCTTTATTTAAAAAAAA
CTACAACCTAGTGACTGTATTGGTCATAAGCATGATTGTTGTTGCAATGTGCTACTTACA
ATGAATGACTGACAGAAAACAAGCTAGGGATCCTGTCTGCAGCTTCCAGCCTTTCCTCTT
TTTATTTCAGTAGGCATCAATGATAAATCAATCTTATGTACAATTTCTTACAACTAGCCC
CTTTACCTTNTGCANNGATACTTTACACTCATACAACTTNCTAATATCTGAGAACTATTT
AAATATTCTAAATGCATANAAATAAGATTTCGCCTTTTGAATATATAAATATTATTCCTG
TACTCAAAATGGAGCTCAACTCCNCCCCAAAATATCTCTGCTGGGCAGTGCTGATTGCCC
TCTAGGAATCTGCAGCTACGTCCTCTTGTCCCAGCTGACACAACATCTTCTGATTT
Restriction Sites NotI-NotI     
ACCN NM_003744
Insert Size 2440 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq NM_003744.1, NP_003735.1
RefSeq Size 3614 bp
RefSeq ORF 408 bp
Locus ID 8650
UniProt ID P49757
Domains PID
Protein Pathways Notch signaling pathway
Gene Summary The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
Transcript Variant: This variant (3) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (3) has the same N- and C-termini but is shorter compared to isoform 1.
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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