eIF4GII (EIF4G3) (NM_003760) Human Untagged Clone

CAT#: SC117780

EIF4G3 (untagged)-Human eukaryotic translation initiation factor 4 gamma, 3 (EIF4G3), transcript variant 3



  "NM_003760" in other vectors (4)

CNY 10,856.00


货期*
现货

规格
    • 10 ug

Product images

经常一起买 (4)
TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00


Rabbit Polyclonal Anti-EIF4G3 Antibody
    • 100 ul

CNY 5,250.00

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Synonyms eIF-4G 3; eIF4G 3; eIF4GII
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC117780 sequence for NM_003760 edited (data generated by NextGen Sequencing)
ATGAATTCACAACCTCAAACCCGTTCTCCGTTTTTCCAGAGGCCTCAAATACAGCCTCCT
AGAGCTACCATCCCGAACAGCAGTCCTTCCATTCGTCCTGGTGCACAGACACCCACTGCA
GTGTACCAGGCTAATCAGCACATCATGATGGTTAACCATCTGCCCATGCCGTACCCAGTG
CCCCAGGGGCCTCAGTACTGTATACCACAGTACCGTCATAGTGGCCCTCCTTATGTTGGG
CCCCCCCAACAATATCCAGTTCAACCACCGGGGCCAGGTCCTTTTTATCCTGGACCAGGA
CCTGGGGACTTCCCCAATGCTTATGGAACGCCTTTTTACCCAAGTCAGCCGGTGTATCAG
TCAGCACCTATCATAGTGCCTACGCAGCAACAGCCGCCTCCAGCCAAGAGAGAGAAAAAA
ACTATAAGAATTCGGGATCCAAACCAGGGAGGTAAAGACATAACAGAGGAGATTATGTCT
GGAGGTGGCAGCAGAAATCCTACTCCACCCATAGGAAGACCCACGTCCACACCTACTCCT
CCTCAGCAGCTGCCCAGCCAGGTCCCCGAGCACAGCCCTGTGGTTTATGGGACTGTGGAG
AGCGCTCATCTTGCTGCCAGCACCCCTGTCACTGCAGCTAGCGACCAGAAGCAAGAGGAG
AAGCCAAAACCAGATCCAGTGTTAAAGTCTCCTTCCCCAGTCCTTAGGCTAGTCCTCAGT
GGAGAGAAGAAAGAACAAGAAGGCCAGACATCTGAAACTACTGCAATAGTATCCATAGCA
GAGCTTCCTCTGCCTCCATCACCTACCACTGTTTCTTCTGTTGCTCGAAGTACAATTGCA
GCCCCCACCTCTTCTGCTCTTAGTAGCCAACCAATATTCACCACTGCTATAGATGACAGA
TGTGAACTCTCATCCCCAAGAGAAGACACAATTCCTATACCCAGCCTCACATCTTGCACA
GAAACATCAGACCCTTTACCAACAAATGAAAATGATGATGATATATGCAAGAAACCCTGT
AGTGTAGCACCTAATGATATTCCACTGGTTTCTAGTACTAACCTAATTAATGAAATAAAT
GGAGTTAGCGAAAAATTATCAGCCACGGAGAGCATTGTGGAAATAGTAAAACAGGAAGTA
TTGCCATTGACTCTTGAATTGGAGATTCTCGAAAATCCCCCAGAAGAAATGAAACTGGAG
TGTATCCCAGCTCCCATCACCCCTTCCACAGTTCCTTCCTTTCCTCCAACTCCTCCAACT
CCTCCAGCTTCTCCTCCTCACACTCCAGTCATTGTTCCTGCTGCTGCCACTACTGTTAGT
TCTCCGAGTGCTGCCATCACAGTCCAGAGAGTCCTAGAGGAGGACGAGAGCATAAGAACT
TGCCTTAGTGAAGATGCAAAAGAGATTCAGAACAAAATAGAGGTAGAAGCAGATGGGCAA
ACAGAAGAGATTTTGGATTCTCAAAACTTAAATTCAAGAAGGAGCCCTGTCCCAGCTCAA
ATAGCTATAACTGTACCAAAGACATGGAAGAAACCAAAAGATCGGACCCGAACCACTGAA
GAGATGTTAGAGGCAGAATTGGAGCTTAAAGCTGAAGAGGAGCTTTCCATTGACAAAGTA
CTTGAATCTGAACAAGATAAAATGAGCCAGGGGTTTCATCCTGAAAGAGACCCCTCTGAC
CTAAAAAAAGTGAAAGCTGTGGAAGAAAATGGAGAAGAAGCTGAGCCAGTACGTAATGGT
GCTGAGAGTGTTTCTGAGGGTGAAGGAATAGATGCTAATTCAGGCTCCACAGATAGTTCT
GGTGATGGGGTTACATTTCCATTTAAACCAGAATCCTGGAAGCCTACTGATACTGAAGGT
AAGAAGCAGTATGACAGGGAGTTTCTGCTGGACTTCCAGTTCATGCCTGCCTGTATACAA
AAACCAGAGGGCCTGCCTCCTATCAGTGATGTGGTTCTTGACAAGATCAACCAACCCAAA
TTGCCAATGCGAACTCTGGATCCTCGAATTTTGCCTCGAGGACCAGACTTTACACCAGCC
TTTGCTGATTTTGGAAGGCAGACACCTGGTGGAAGAGGCGTACCTTTGTTGAATGTTGGG
TCACGAAGATCTCAACCTGGCCAAAGAAGAGAACCCAGAAAGATCATCACAGTTTCTGTA
AAAGAAGATGTACACCTGAAAAAGGCAGAAAATGCCTGGAAGCCAAGCCAAAAACGAGAC
AGCCAAGCCGATGATCCCGAAAACATTAAAACCCAGGAGCTTTTTAGAAAAGTTCGAAGT
ATCTTAAATAAATTGACACCACAGATGTTCAATCAACTGATGAAGCAAGTGTCAGGACTT
ACTGTTGACACAGAGGAGCGGCTGAAAGGAGTTATTGACCTGGTCTTTGAGAAGGCTATT
GATGAACCCAGTTTCTCTGTGGCTTACGCAAACATGTGTCGATGTCTAGTAACGCTGAAA
GTACCCATGGCAGACAAGCCTGGTAACACAGTGAATTTCCGGAAGCTGCTACTGAACCGT
TGCCAGAAGGAGTTTGAAAAAGATAAAGCAGATGATGATGTCTTTGAGAAGAAGCAGAAA
GAACTTGAGGCTGCCAGTGCTCCAGAGGAGAGGACAAGGCTTCATGATGAACTGGAAGAA
GCCAAGGACAAAGCCCGGCGGAGATCCATTGGCAACATCAAGTTTATTGGAGAACTCTTT
AAACTCAAAATGCTGACTGAAGCCATCATGCATGACTGTGTGGTGAAGCTGCTAAAGAAC
CATGATGAAGAATCCCTGGAGTGCCTGTGTCGCCTGCTCACCACCATTGGCAAAGACTTG
GACTTTGAAAAAGCAAAGCCACGTATGGACCAGTACTTTAATCAGATGGAGAAAATTGTG
AAAGAAAGAAAAACCTCATCTAGGATTCGGTTCATGCTTCAAGATGTTATAGACCTAAGG
CTGTGCAATTGGGTATCTCGAAGAGCAGATCAAGGGCCTAAAACTATCGAACAGATTCAC
AAAGAGGCTAAAATAGAAGAACAAGAAGAGCAAAGGAAGGTCCAGCAACTCATGACCAAA
GAGAAGAGAAGACCAGGTGTCCAGAGAGTGGACGAAGGTGGGTGGAACACTGTACAAGGG
GCCAAGAACAGTCGGGTACTGGACCCCTCAAAATTCCTAAAAATCACTAAGCCTACAATT
GATGAAAAAATTCAGCTGGTACCTAAAGCACAGCTAGGCAGCTGGGGAAAAGGCAGCAGT
GGTGGAGCAAAGGCAAGTGAGACTGATGCCTTACGGTCAAGTGCTTCCAGTTTAAACAGA
TTCTCTGCCCTGCAACCTCCAGCACCCTCAGGGTCCACGCCATCCACGCCTGTAGAGTTT
GATTCCCGAAGGACCTTAACTAGTCGTGGAAGTATGGGCAGGGAGAAGAATGACAAGCCC
CTTCCATCTGCAACAGCTCGGCCAAATACTTTCATGAGGGGTGGCAGCAGTAAAGACCTG
CTAGACAATCAGTCTCAAGAAGAGCAGCGGAGAGAGATGCTGGAGACCGTGAAGCAGCTC
ACAGGAGGTGTGGATGTGGAGAGGAACAGCACTGAGGCTGAGCGAAATAAAACAAGGGAG
TCAGCAAAACCAGAAATTTCAGCAATGTCAGCTCATGACAAGGCTGCATTATCAGAAGAG
GAACTGGAGAGGAAGTCGAAATCTATCATTGATGAATTTCTACACATTAATGATTTTAAG
GAAGCCATGCAGTGTGTGGAAGAGCTGAATGCCCAGGGCCTACTACATGTTTTTGTGAGA
GTGGGAGTGGAGTCCACCCTGGAAAGGAGCCAGATCACCAGGGATCACATGGGCCAACTA
CTCTATCAGCTGGTACAGTCAGAAAAACTCAGCAAACAGGACTTTTTCAAAGGTTTTTCA
GAAACTTTGGAATTGGCAGATGACATGGCCATTGATATTCCCCATATTTGGTTGTACCTT
GCTGAACTGGTGACCCCCATGTTAAAAGAAGGTGGAATCTCCATGAGAGAACTTACCATA
GAATTTAGCAAACCTTTACTTCCTGTTGGAAGAGCTGGGGTCTTGCTATCTGAAATATTG
CACCTACTATGCAAACAAATGAGCCATAAGAAAGTGGGAGCCTTATGGAGGGAGGCTGAC
CTCAGCTGGAAGGACTTTTTACCAGAAGGAGAAGATGTACATAATTTTCTTTTGGAGCAG
AAGTTGGACTTCATAGAGTCTGACAGTCCCTGTTCCTCTGAAGCACTTTCAAAGAAAGAA
CTGTCTGCCGAAGAGCTGTATAAGCGACTCGAGAAACTCATTATTGAGGACAAAGCGAAT
GATGAACAGATCTTTGACTGGGTAGAGGCTAATCTAGACGAAATCCAGATGAGTTCACCT
ACATTCCTTAGAGCTTTAATGACTGCTGTTTGTAAAGCAGCTATTATAGCCGACTCTTCT
ACCTTCAGAGTGGACACTGCTGTTATCAAGCAGAGAGTGCCGATCTTACTCAAGTACCTA
GACTCAGATACAGAGAAGGAACTGCAAGCACTTTATGCACTACAAGCATCGATAGTAAAA
CTTGATCAACCTGCCAATTTGCTGCGGATGTTTTTTGATTGTCTATATGACGAGGAGGTG
ATCTCCGAGGATGCCTTCTACAAATGGGAGAGCAGCAAGGACCCTGCAGAGCAGAATGGG
AAGGGCGTGGCTCTGAAATCTGTCACGGCATTCTTCACGTGGCTGCGGGAAGCAGAAGAG
GAGTCTGAGGATAACTAA

Clone variation with respect to NM_003760.4
3838 t=>c
>OriGene 5' read for NM_003760 unedited
CCGCGTAATTCGGCACGAGGGTCCCCCCTCCNACCCGAACATCAGGGCCCTCCAGACTCA
GGCGCCCCAACAAATTCCTAGAGGACCTGTGCAACAACCTCTTGAGGATCGAATCTTCAC
TCCCGCTGTCTCAGCAGTCTACAGCACGGTAACACAAGTGGCAAGACAGCCGGGAACCCC
TACCCCATCCCCTTATTCAGCACATGAAATAAACAAGGGGCATCCAAATCTTGCGGCAAC
GCCCCCGGGACATGCATCGTCCCCTGGACTCTCTCAAACCCCTTATCCCTCTGGACAGAA
TGCAGGTCCAACCACGCTGGTATACCCTCAAACCCCTCAGACAATGAATTCACAACCTCA
AACCCGTTCTCCGTTTTTCCAGAGGCCTCAAATACAGCCTCCTAGAGCTACCATCCCGAA
CAGCAGTCCTTCCATTCGTCCTGGTGCACAGACACCCACTGCAGTGTACCAGGCTAATCA
GCACATCATGATGGTTAACCATCTGCCCATGCCGTACCCAGTGCCCCAGGGGCCTCAGTA
CTGTATACCACAGTACCGTCATAGTGGCCCTCCTTATGTTGGGCCCCCCCAACAATATCC
AGTTCAACCACCGGGGCCAGGTCCTTTNTATCCTGGACCAGGACCTGGGGACTTCCCCAA
TGCTTATGGAACGCCTTTTTACCCAGTCAGCCGGTGTATCAGTCAGCACCTATCATAGTG
CCTACGCAGCAACAGCCGNCTTCAGCCAAGAGAGAGAAAAAACTATTAGAATTCGGGATC
CAACCAGGGGAGTAAAGACAAACAGAGGAGATATGTCTGGAGTGGCAGCAGAATCCTACT
CCACCATAGGA
>OriGene 3' read for NM_003760 unedited
TATGGACCGGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTAAACAATTCTT
GGAGTTCTGTGGTCCACAGCATTTCCTTCTGTTTCAATGTTATGTATGTTTTGATTACTA
TTGTGATTTTTTAAATTTTCTGAAGCAAGCTGAGAGGCAGGCAGAAAGATTTGATGCCAA
AAAAAAAAAAAATCTTTCTTACCTTGTTCACCCCAAACTTTCTCAAATCTGGACTAAATG
CTATACCTTAAAACAAACATGAGGTGCATCTTGAAGGGGAGGGAAATTTATTTCTCTGCT
TTTCTATTATACAAGTTGTTTACAGAAACTGCAAATTAAAAAATTACACTGGCATTTGCA
GTCCTTAAAATAAATTAAAAGTTCTCAACTTTTTTTTTTTTTGCTAAACATTTTTTTAAG
TATGAGTCCTTGTTTAAAAAGAAAAGATTAAAACAGAAAATATTTTCTATAAATAATACA
TGTATTTTGGTTTTAGTGCTCCCGCCCTAAGGTTTGAAGTTTACTTTTATCCAGTACCTT
TTTCCTCCATGACCACCTTTTTTTCTCTTTCCCCTCTCCCACTCGTGCACACGTGGGGGT
TTCTGCGAGAATTGGCCTTGCTGCACTGNGATTGGCGAAGACGTGAAACTTTCTAAAAAA
AACTTAAACCGTTCCTTTTGTTTCTTTTGTGCATTTGAAGTTTTAGTTATCCTCAAACTC
CTCTTCTGCTTCCCGAAGCCACGCGAAGAATGCCGTGACAGATTTCAAAAGCACGCCCTT
CCCATTTTGTTTGCCAGGTCCCTGCTGCTCTCCCCATTGTAGACGCCTCCTTGGCAATCA
CCTCCTGTGTATAAGACATTAAAAAAATTCGNACCAATTGGCGGGTGGACAAGCTTACTC
TCGAGCTTGCACGGCACAAGGGCTGGACCCCTTCCTTGTATCCGTCCCAGGACCTGGACC
AGATCGGCCTTTCTGCTGACACCCCACGGTCCCACGTCCGTCCG
Restriction Sites NotI-NotI     
ACCN NM_003760
Insert Size 5650 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq NM_003760.2, NP_003751.2
RefSeq Size 5880 bp
RefSeq ORF 4758 bp
Locus ID 8672
UniProt ID O43432
Domains eIF5C, MIF4G, MA3
Protein Families Transcription Factors
Protein Pathways Viral myocarditis
Gene Summary The protein encoded by this gene is thought to be part of the eIF4F protein complex, which is involved in mRNA cap recognition and transport of mRNAs to the ribosome. Interestingly, a microRNA (miR-520c-3p) has been found that negatively regulates synthesis of the encoded protein, and this leads to a global decrease in protein translation and cell proliferation. Therefore, this protein is a key component of the anti-tumor activity of miR-520c-3p. [provided by RefSeq, May 2016]
Transcript Variant: This variant (3) lacks an in-frame exon in the CDS, as compared to variant 1. The resulting isoform (3) lacks an internal segment, as compared to isoform 1.
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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