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HYAL2 (NM_003773) Human Untagged Clone
CAT＃: SC117754
HYAL2 (untagged)-Human hyaluronoglucosaminidase 2 (HYAL2), transcript variant 1
CNY 3,656.00
| Cited in 2 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | LUCA2 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC117754 sequence for NM_003773 edited (data generated by NextGen Sequencing)
ATGCGGGCAGGCCCAGGCCCCACCGTTACATTGGCCCTGGTGCTGGCGGTGGCATGGGCC ATGGAGCTCAAGCCCACAGCACCACCCATCTTCACTGGCCGGCCCTTTGTGGTAGCGTGG GACGTGCCCACACAGGACTGTGGCCCACGCCTCAAGGTGCCACTGGACCTGAATGCCTTT GATGTGCAGGCCTCACCTAATGAGGGTTTTGTGAACCAGAATATTACCATCTTCTACCGC GACCGTCTAGGCCTGTATCCACGCTTCGATTCTGCCGGAAGGTCTGTGCATGGTGGTGTG CCACAGAATGTCAGCCTTTGGGCACACCGGAAGATGCTGCAGAAACGTGTGGAGCACTAC ATTCGGACACAGGAGTCTGCGGGGCTGGCGGTCATCGACTGGGAGGACTGGCGACCTGTG TGGGTGCGCAACTGGCAGGACAAAGATGTGTATCGCCGGTTATCACGCCAGCTAGTGGCC AGTCGTCACCCTGACTGGCCTCCAGACCGCATAGTCAAACAGGCACAATATGAGTTTGAG TTCGCAGCACAGCAGTTCATGCTGGAGACACTGCGTTATGTCAAGGCAGTGCGGCCCCGG CACCTCTGGGGCTTCTACCTCTTTCCTGACTGCTACAATCATGATTATGTGCAGAACTGG GAGAGCTACACAGGCCGCTGCCCTGATGTTGAGGTGGCCCGCAATGACCAGCTGGCCTGG CTGTGGGCTGAGAGCACGGCCCTCTTCCCGTCTGTCTACCTGGACGAGACACTTGCTTCC TCCCGCCATGGCCGCAACTTTGTGAGCTTCCGTGTTCAGGAGGCCCTTCGTGTGGCTCGC ACCCACCATGCCAACCATGCACTCCCAGTCTACGTCTTCACACGACCCACCTACAGCCGC AGGCTCACGGGGCTTAGTGAGATGGACCTCATCTCTACCATTGGCGAGAGTGCGGCCCTG GGCGCAGCTGGTGTCATCCTCTGGGGTGACGCGGGGTACACCACAAGCACGGAGACCTGC CAGTACCTCAAAGATTACCTGACACGGCTGCTGGTCCCCTACGTGGTCAATGTGTCCTGG GCCACCCAATATTGCAGCCGGGCCCAGTGCCATGGCCATGGGCGCTGTGTGCGCCGCAAC CCCAGTGCCAGTACCTTCCTGCATCTCAGCACCAACAGTTTCCGCCTAGTGCCTGGCCAT GCACCTGGTGAACCCCAGCTGCGACCTGTGGGGGAGCTCAGTTGGGCCGACATTGACCAC CTGCAGACACACTTCCGCTGCCAGTGCTACTTGGGCTGGAGTGGTGAGCAATGCCAGTGG GACCATAGGCAGGCAGCTGGAGGTGCCAGCGAGGCCTGGGCTGGGTCCCACCTCACCAGT CTGCTGGCTCTGGCAGCCCTGGCCTTTACCTGGACCTTGTAG Clone variation with respect to NM_003773.4 52 t=>g >OriGene 5' read for NM_003773 unedited
NGGTCGAATTTGTATACGACTCATATAGGGCGGCCGCGAATTCGCACGAGGGCGAGTTCC TGAGCTGGTGCCAGGCAGGTGACACCTCCTGCAGCCCCCAGCATGCGGGCAGGCCCAGGC CCCACCGTTACATTGGCCCTGGTGCTGGCGGTGGCATGGGCCATGGAGCTCAAGCCCACA GCACCACCCATCTTCACTGGCCGGCCCTTTGTGGTAGCGTGGGACGTGCCCACACAGGAC TGTGGCCCACGCCTCAAGGTGCCACTGGACCTGAATGCCTTTGATGTGCAGGCCTCACCT AATGAGGGTTTTGTGAACCAGAATATTACCATCTTCTACCGCGACCGTCTAGGCCTGTAT CCACGCTTCGATTCTGCCGGAAGGTCTGTGCATGGTGGTGTGCCACAGAATGTCAGCCTT TGGGCACACCGGAAGATGCTGCAGAAACGTGTGGAGCACTACATTCGGACACAGGAGTCT GCGGGGCTGGCGGTCATCGACTGGGAGGACTGGCGACCTGTGTGGGTGCGCAACTGGCAG GACAAAGATGTGTATCGCCGGTTATCACGCCAGCTAGTGGCCAGTCGTCACCCTGACTGG CCTCCAGACCGCATAGTCAAACAGGCACAATATGAGNTTTGAGTTCGCAGCACAGCAGTT CATGCTGGAGACACTGCGTTATGTCAAGGCAGTGCGGCCCCGGCACCTCTGGGGCTTCTA CCTCTTTCCTGACTGCTACAATCATGNATTATGTGCAGAACTGGGAGAGCTACACAGGCC GCTGCCCTGATGTTTGAGGTGGCCCGCAATGACCAGCTGCCCTGGCTGTGGGCTGAGACA CGGNCCTCTTCCCGTCTGTCTANCTGGACGAGACACTTGCTTTCTCCGNCATGGCGCNNA CTTNGAGCC >OriGene 3' read for NM_003773 unedited
AATTTTGGNACCGCGGCCGCATNCTAGGATCGAGTTTTTTTTTTTTTTTTTTGGTTTATG TTTAATTTACAAAAGAGACCCCAAAATAATAATAATAATAAACTATCTAGGGCAAGGGAG TAGGGTCAGGTCCTCCCCAGCCCAGCTGTACCCTCCTTCCCCTCTGGCAGGGAGAGAAGG GGCCTCCCAGGGACTTCCCCTCCCCCTTAGAACAGGGGGGTGCGAGCTGGTATGGATGCC CTCCTGGGCTTCCTGGGGGCTCTGCCCACTCCAGACTCCAGTTTGTCCACCCCCTGCAGG GTCCTACATGCCTAAGAGAGCCCTTGTGGTAGAGGCCAGCTTGCTAGGCAGCTAGGCAGG AGACCCCTACAAGGTCCAGGTAAAGGCCAGGGCTGCCAGAGCCAGCAGACTGGTGAGGTG GGACCCAGCCCAGGCCTCGCTGGCACCTCCAGCTGCCTGCCTATGGTCCCACTGGCATTG CTCACCACTCCAGCCCAAGTAGCACTGGCAGCGGAAGTGTGTCTGCAGGTGGTCAATGTC GGCCCAACTGAGCTCCCCCACAGGTCGCAGCTGGGGTTCACCAGGTGCATGGCCAGGCAC TANGCGGAAACTGTTGGTGCTGAGATGCANGAAGGTACTGGCACTGGGGTTGCGGGGCAC ACAGCGCCCATGGCCATGGCACTGGGCCCGGGTGCAATAATGGGGTGGCCAGGGCACATT TGACCACCGTAGGGACCAGCAGCCGTGTCAAGTAATCTTTGAGGGCCTGGCAAGCCTCCG GGCTTGGGGGGACCCCCCGTAACCCCAAAGAAGACACCAGCTGGGCCCCAGGGCCGGACT CTCGCCCATGGTANAGAAGGAGGGCCCATCTCACTAACCCCCGGAACCTGCCGCTGTAAG GGGGGCCGGGGAAAACCCAAACTGGGATGCCTG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_003773 |
| Insert Size | 1830 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_003773.2, NP_003764.3 |
| RefSeq Size | 1848 bp |
| RefSeq ORF | 1422 bp |
| Locus ID | 8692 |
| UniProt ID | Q12891 |
| Domains | Glyco_hydro_56 |
| Protein Families | Druggable Genome |
| Protein Pathways | Glycosaminoglycan degradation, Metabolic pathways |
| Gene Summary | This gene encodes a weak acid-active hyaluronidase. The encoded protein is similar in structure to other more active hyaluronidases. Hyaluronidases degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan and fragments of hyaluronan are thought to be involved in cell proliferation, migration and differentiation. Although it was previously thought to be a lysosomal hyaluronidase that is active at a pH below 4, the encoded protein is likely a GPI-anchored cell surface protein. This hyaluronidase serves as a receptor for the oncogenic virus Jaagsiekte sheep retrovirus. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. This gene encodes two alternatively spliced transcript variants which differ only in the 5' UTR.[provided by RefSeq, Mar 2010] Transcript Variant: This variant (1) represents the shorter transcript. Both variants 1 and 2 encode the same protein. |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Midgut Laterality Is Driven by Hyaluronan on the Right
,Sivakumar, A;Mahadevan, A;Lauer, ME;Narvaez, RJ;Ramesh, S;Demler, CM;Souchet, NR;Hascall, VC;Midura, RJ;Garantziotis, S;Frank, DB;Kimata, K;Kurpios, NA;,
Dev. Cell
,PubMed ID 30174180
[HYAL2]
|
|
High molecular weight hyaluronan mediates the cancer resistance of the naked mole-rat
,null,
Nature
,PubMed ID 23783513
[HYAL2]
|
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC214453 | HYAL2 (Myc-DDK-tagged)-Human hyaluronoglucosaminidase 2 (HYAL2), transcript variant 1 |
CNY 3,656.00 |
|
| RC214453L1 | Lenti ORF clone of Human hyaluronoglucosaminidase 2 (HYAL2), transcript variant 1, Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC214453L2 | Lenti ORF clone of Human hyaluronoglucosaminidase 2 (HYAL2), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RC214453L3 | Lenti ORF clone of Human hyaluronoglucosaminidase 2 (HYAL2), transcript variant 1, Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC214453L4 | Lenti ORF clone of Human hyaluronoglucosaminidase 2 (HYAL2), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RG214453 | HYAL2 (tGFP-tagged) - Human hyaluronoglucosaminidase 2 (HYAL2), transcript variant 1 |
CNY 5,256.00 |
