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AP2M1 (NM_004068) Human Untagged Clone
CAT＃: SC117611
AP2M1 (untagged)-Human adaptor-related protein complex 2, mu 1 subunit (AP2M1), transcript variant 1
CNY 3,656.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | AP50; CLAPM1; MRD60; mu2 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC117611 sequence for NM_004068 edited (data generated by NextGen Sequencing)
ATGATTGGAGGCTTATTCATCTATAATCACAAGGGGGAGGTGCTCATCTCCCGAGTCTAC CGAGATGACATCGGGAGGAACGCAGTGGATGCCTTTCGGGTCAATGTTATCCATGCCCGG CAGCAGGTGCGCAGCCCCGTCACCAACATTGCTCGCACCAGCTTCTTCCACGTTAAGCGG TCCAACATTTGGCTGGCAGCAGTCACCAAGCAGAATGTCAACGCTGCCATGGTCTTCGAA TTCCTCTATAAGATGTGTGACGTGATGGCTGCCTACTTTGGCAAGATCAGCGAGGAAAAC ATCAAGAACAATTTTGTGCTCATATATGAGCTGCTGGATGAGATTCTAGACTTTGGCTAC CCACAGAATTCCGAGACAGGCGCGCTGAAAACCTTCATCACGCAGCAGGGCATCAAGAGT CAGCATCAGACAAAAGAAGAGCAGTCACAGATCACCAGCCAGGTAACTGGGCAGATTGGC TGGCGGCGAGAGGGTATCAAGTATCGTCGGAATGAGCTCTTCCTGGATGTGCTGGAGAGT GTGAACCTGCTCATGTCCCCACAAGGGCAGGTGCTGAGTGCCCATGTGTCGGGCCGGGTG GTGATGAAGAGCTACCTGAGTGGCATGCCTGAATGCAAGTTTGGGATGAATGACAAGATT GTTATTGAAAAGCAGGGCAAAGGCACAGCTGATGAAACAAGCAAGAGCGGGAAGCAATCA ATTGCCATTGATGACTGCACCTTCCACCAGTGTGTGCGACTCAGCAAGTTTGACTCTGAA CGCAGCATCAGCTTTATCCCGCCAGATGGAGAGTTTGAGCTTATGAGGTATCGCACAACC AAGGACATCATCCTTCCCTTCCGGGTGATCCCGCTAGTGCGAGAAGTGGGACGCACCAAA CTGGAGGTCAAGGTGGTCATCAAGTCCAACTTTAAACCCTCACTGCTGGCTCAGAAGATC GAGGTGAGGATCCCAACCCCACTGAACACAAGCGGGGTGCAGGTGATCTGCATGAAGGGG AAGGCCAAGTACAAGGCCAGCGAGAATGCCATCGTGTGGAAGATCAAGCGCATGGCAGGC ATGAAGGAATCGCAGATCAGCGCAGAGATTGAGCTTCTGCCTACCAACGACAAGAAGAAA TGGGCTCGACCCCCCATTTCCATGAACTTTGAGGTGCCATTCGCGCCCTCTGGCCTCAAG GTGCGCTACTTGAAGGTGTTTGAACCGAAGCTGAACTACAGCGACCATGATGTCATCAAA TGGGTGCGCTACATTGGCCGCAGTGGCATTTATGAAACTCGCTGCTAG Clone variation with respect to NM_004068.3 >OriGene 5' read for NM_004068 unedited
TACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCCGAGGCAGCGGGCAGACGAG CAGGGGGCGGGCGGACATCTTGGGATCCGGAGAGTGGCCGGGCCGGCAGAGCAGGGGGCC GAGGACACCAGGTCTGTTCTCAGAGCGATGGGCCGCGGAGACTGATCTGCCGCCATGATT GGAGGCTTATTCATCTATAATCACAAGGGGGAGGTGCTCATCTCCCGAGTCTACCGAGAT GACATCGGGAGGAACGCAGTGGATGCCTTTCGGGTCAATGTTATCCATGCCCGGCAGCAG GTGCGCAGCCCCGTCACCAACATTGCTCGCACCAGCTTCTTCCACGTTAAGCGGTCCAAC ATTTGGCTGGCAGCAGTCACCAAGCAGAATGTCAACGCTGCCATGGTCTTCGAATTCCTC TATAAGATGTGTGACGTGATGGCTGCCTACTTTGGCAAGATCAGCGAGGAAAACATCAAG AACAATTTTGTGCTCATATATGAGCTGCTGGATGAGATTCTAGACTTTGGCTACCCACAG AATTCCGAGACAGGCGCGCTGAAAACCTTCATCACGCAGCAGGGCATCAAGAGTCAGCAT CAGACAAAAGAAGAGCAGTCACAGATCACCAGCCAGGTAACTGGGCAGATTGGCTGGCGG CGAGAGGGTATCAAGTATCGTCGGAATGAGCTCTTCCTGGATGTGCTGGAGAGTGTGAAC CTGCTCATGTCCCCACAGGGGCAGGTGCTGAGTGCCCATGTGTCGGGCCGGGTGGTGATG AANAGCTACCTGAGTGGCATGCCTGAAATGCAGTTTGGGATGAAATGACAAGATTGTTAT TGAAAAGCAGGNCANAGGCACAGCTGATGAAACAAAGCAGAGCGGAAGCATCAATTGCAT TGTGACTGCACCTTCACCATGTGTGCGATCANCAGTTGACTCGACGCACATAGCTTTATC CGCGAN >OriGene 3' read for NM_004068 unedited
TTTTTTTTCTTCCACACCTTCTACACAAATTTTATTGGGTTTGTAACTGGACGAAGTCAC ACGTGTACAAAATGAAGCTCACACTATCCCAAAGCAGAAGNTAGGGACTGAGGCCGGGGA TCCATTACTGGCCTTTGGGGGGAGCTCTGAGGTGAGGGG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_004068 |
| Insert Size | 2000 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_004068.3, NP_004059.2 |
| RefSeq Size | 1958 bp |
| RefSeq ORF | 1308 bp |
| Locus ID | 1173 |
| UniProt ID | Q96CW1 |
| Domains | Adap_comp_sub |
| Protein Families | Druggable Genome |
| Protein Pathways | Endocytosis, Huntington's disease |
| Gene Summary | This gene encodes a subunit of the heterotetrameric coat assembly protein complex 2 (AP2), which belongs to the adaptor complexes medium subunits family. The encoded protein is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes. The encoded protein may also play an important role in regulating the intracellular trafficking and function of CTLA-4 protein. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2015] Transcript Variant: This variant (1) lacks two alternate in-frame exons compared to variant 3. The resulting isoform (a) has the same N- and C-termini but is shorter compared to isoform c. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC218161 | AP2M1 (Myc-DDK-tagged)-Human adaptor-related protein complex 2, mu 1 subunit (AP2M1), transcript variant 1 |
CNY 5,488.00 |
|
| RC218161L1 | Lenti ORF clone of Human adaptor-related protein complex 2, mu 1 subunit (AP2M1), transcript variant 1, Myc-DDK-tagged |
CNY 7,888.00 |
|
| RC218161L2 | Lenti ORF clone of Human adaptor-related protein complex 2, mu 1 subunit (AP2M1), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RC218161L3 | Lenti ORF clone of Human adaptor-related protein complex 2, mu 1 subunit (AP2M1), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC218161L4 | Lenti ORF clone of Human adaptor-related protein complex 2, mu 1 subunit (AP2M1), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RG218161 | AP2M1 (tGFP-tagged) - Human adaptor-related protein complex 2, mu 1 subunit (AP2M1), transcript variant 1 |
CNY 7,088.00 |
