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CMKLR1 (NM_004072) Human Untagged Clone
CAT＃: SC117575
CMKLR1 (untagged)-Human chemokine-like receptor 1 (CMKLR1), transcript variant 2
CNY 3,656.00
CNY 6,080.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CHEMERINR; ChemR23; DEZ; RVER1 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC117575 sequence for NM_004072 edited (data generated by NextGen Sequencing)
ATGGAGGATGAAGATTACAACACTTCCATCAGTTACGGTGATGAATACCCTGATTATTTA GACTCCATTGTGGTTTTGGAGGACTTATCCCCCTTGGAAGCCAGGGTGACCAGGATCTTC CTGGTGGTGGTCTACAGCATCGTCTGCTTCCTCGGGATTCTGGGCAATGGTCTGGTGATC ATCATTGCCACCTTCAAGATGAAGAAGACAGTGAACATGGTCTGGTTCCTCAACCTGGCA GTGGCAGATTTCCTGTTCAACGTCTTCCTCCCAATCCATATCACCTATGCCGCCATGGAC TACCACTGGGTTTTCGGGACAGCCATGTGCAAGATCAGCAACTTCCTTCTCATCCACAAC ATGTTCACCAGCGTCTTCCTGCTGACCATCATCAGCTCTGACCGCTGCATCTCTGTGCTC CTCCCTGTCTGGTCCCAGAACCACCGCAGCGTTCGCCTGGCTTACATGGCCTGCATGGTC ATCTGGGTCCTGGCTTTCTTCTTGAGTTCCCCATCTCTCGTCTTCCGGGACACAGCCAAC CTGCATGGGAAAATATCCTGCTTCAACAACTTCAGCCTGTCCACACCTGGGTCTTCCTCG TGGCCCACTCACTCCCAAATGGACCCTGTGGGGTATAGCCGGCACATGGTGGTGACTGTC ACCCGCTTCCTCTGTGGCTTCCTGGTCCCAGTCCTCATCATCACAGCTTGCTACCTCACC ATCGTGTGCAAACTGCAGCGCAACCGCCTGGCCAAGACCAAGAAGCCCTTCAAGATTATT GTGACCATCATCATTACCTTCTTCCTCTGCTGGTGCCCCTACCACACACTCAACCTCCTA GAGCTCCACCACACTGCCATGCCTGGCTCTGTCTTCAGCCTGGGTTTGCCCCTGGCCACT GCCCTTGCCATTGCCAACAGCTGCATGAACCCCATTCTGTATGTTTTCATGGGTCAGGAC TTCAAGAAGTTCAAGGTGGCCCTCTTCTCTCGCCTGGTCAATGCTCTAAGTGAAGATACA GGCCACTCTTCCTACCCCAGCCATAGAAGCTTTACCAAGATGTCATCAATGAATGAGAGG ACTTCTATGAATGAGAGGGAGACCGGCATGCTTTGA Clone variation with respect to NM_004072.2 >OriGene 5' read for NM_004072 unedited
CCCCGTTCAGAATTGTATACGACTCATATAGGCGGCCGCGNAATCGGCACGAGGGNAAGC AGCTCCCGGCGNGCCAGCAGGGTAGCTCAGGACAGAGCAGGCTCCCTGGGAAGCCTCCGG GTGATAGGGGTGTTCCAGCTGCGGCGCTCTGGGGGTTCAGAGGGGGATCTTGAATGAACA AATGAATGAACTGCTTTCTGGGCAAACAGCCACAGCCAGAGGAGCCTGTGATTGGCAGAA AGAAGCCAGGGTGTGCAAGTCTCCCCAACAGCCTCGAGTGGCCTGCAGTCACAGGGAACC CTCAGGAAGACCTTCCGGGCAGAGACCAGAGGGAAGGTGTTTCTAGCTGTGTACAGGGAC TGATTGGCTGAGGACTCACATTGGAGAGCTGCAGACAACATAACGGTGAATGAGAATGGA GGATGAAGATTACAACACTTCCATCAGTTACGGTGATGAATACCCTGATTATTTAGACTC CATTGTGGTTTTGGAGGACTTATCCCCCTTGGAAGCCAGGGTGACCAGGATCTTCCTGGT GGTGGTCTACAGCATCGTCTGCTTCCTCGGGATTCTGGGCAATGGTCTGGTGATCATCAT TGCCACCTTCAAGATGAAGAAGACAGTGAACATGGTCTGGTTCCTCAACCTGGCAGTGGC AGATTTCCTGTTCAACGTCTTCCTCCCAATCCATATCACCTATGCCGCCATGGACTACCA CTGGGTTTTCGGGACAGCCATGTGCAAGATCAGCAACTTCCTTCTCATCCACAACATGTT CACCAGCGTCTTCCTGCTGACCATCATCAGCTCTGACCGCTGCATCTCTGTGCTCCTCCC TGTCTGGTCCCAGAACCACCGCAGCGTTCGCCTGGCTTACATGGCCTGG >OriGene 3' read for NM_004072 unedited
GTGATTTTTTCATTTNCTNAAGCCACCCTNCCAGNCCAGNANCTGNAGTGGNATTAGGGA AAGGCAGNAAAAAAATCCCTGTGATGGGGTGAGGGCTGCTGGTGAAGATGCCTGCCACAA CCCCACCCCCAGGTAAGAGGGGCAAGGTGAGATCAGGGGCTGGCACCACCCTGACGCCCC AAATAGCTCCAGCCTAAAGCACCATCAGCCTGCGATGTTCTAGGGTGAGCTGCTCCATGC CTGCATCCTTTAAAGGTTCTTTTCTCCTTTCTCATTTCTTTGCCAAATCTCAAGTCCTCG TTGCATCCCTCACTTGTCTTGCCCTTGCAAAGAGCCCACAGGACCTCTCAGGACCAGTTC TCTGTCTTCCTAGCTGATCCGAAAGCCAAATTCATGGCCTATGGAGTTCATGGGCTGATA TGTCACCTTCCTCTCCCAGATCACCTATGCATTTCCACATACTTTAACACAGAGCAGTGA CTTGAAGGTAGGGTTTTCTGGCCAGCTACTGATAATATATATACAAGGGCCAAGTGTGAT CTGCATCACACTGGGTTTGCTCTGACCCCCTCACTGCTCACACCAGGAATGGACCTTGGA GAGTGTCATTTCTGGGGCACACACAATAGGCAGCTTAATCCCACCGCCCTATGCCAATCC CAGTTCATGGCAATGCTTTTGAGAATTCTTCCTTTTTTGCTNTGAGTCAGTCAAGGCCTG GCCTCCCAAGAAGCATAAATTGCTAGTCCAANGCTGTATGGGACACAGCATGTTCTGTCC ACTANAAGAAAGGGGTTCCNGCCCCTTTATCCCAACCTAAACACTGTTCATTCCATGCAA AATGCATGAAAATTGGTGTATGCTTAAGAGGTCTTGCCCTAGACCTACAAANACATATCC TTGGGTGTCCCTGGGGTGAGAGAGTCAATGAGGGTCCACAGGAGGATAAGCCTGCCGGCT CTCTCCATTAATAAAGCCCTTTTCTGGAGACTTTGGAAAACTTATGGTGGGTAGGAAAAG CGCTTTTTCCTAAACATGCCACGAGAAAAG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_004072 |
| Insert Size | 2630 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_004072.1, NP_004063.1 |
| RefSeq Size | 1900 bp |
| RefSeq ORF | 1116 bp |
| Locus ID | 1240 |
| UniProt ID | Q99788 |
| Domains | 7tm_1 |
| Protein Families | Druggable Genome, GPCR, Transmembrane |
| Gene Summary | Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1. Interaction with RARRES2 induces activation of intracellular signaling molecules, such as SKY, MAPK1/3 (ERK1/2), MAPK14/P38MAPK and PI3K leading to multifunctional effects, like, reduction of immune responses, enhancing of adipogenesis and angionesis. Resolvin E1 down-regulates cytokine production in macrophages by reducing the activation of MAPK1/3 (ERK1/2) and NF-kappa-B. Positively regulates adipogenesis and adipocyte metabolism. Acts as a coreceptor for several SIV strains (SIVMAC316, SIVMAC239, SIVMACL7E-FR and SIVSM62A), as well as a primary HIV-1 strain (92UG024-2).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (2) differs in the 5' UTR and 5' coding sequence, compared to variant 1. It encodes isoform b, which has a shorter N-terminus than isoform a. |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC217247 | CMKLR1 (Myc-DDK-tagged)-Human chemokine-like receptor 1 (CMKLR1), transcript variant 2 |
CNY 3,656.00 |
|
| RC217247L1 | Lenti ORF clone of Human chemokine-like receptor 1 (CMKLR1), transcript variant 2, Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC217247L2 | Lenti ORF clone of Human chemokine-like receptor 1 (CMKLR1), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RC217247L3 | Lenti ORF clone of Human chemokine-like receptor 1 (CMKLR1), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC217247L4 | Lenti ORF clone of Human chemokine-like receptor 1 (CMKLR1), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RG217247 | CMKLR1 (tGFP-tagged) - Human chemokine-like receptor 1 (CMKLR1), transcript variant 2 |
CNY 5,256.00 |
