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Angiotensinogen (AGT) (NM_000029) Human Untagged Clone
CAT＃: SC117553
AGT (untagged)-Human angiotensinogen (serpin peptidase inhibitor, clade A, member 8) (AGT)
CNY 3,656.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ANHU; hFLT1; SERPINA8 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC117553 sequence for NM_000029 edited (data generated by NextGen Sequencing)
ATGCGGAAGCGAGCACCCCAGTCTGAGATGGCTCCTGCCGGTGTGAGCCTGAGGGCCACC ATCCTCTGCCTCCTGGCCTGGGCTGGCCTGGCTGCAGGTGACCGGGTGTACATACACCCC TTCCACCTCGTCATCCACAATGAGAGTACCTGTGAGCAGCTGGCAAAGGCCAATGCCGGG AAGCCCAAAGACCCCACCTTCATACCTGCTCCAATTCAGGCCAAGACATCCCCTGTGGAT GAAAAGGCCCTACAGGACCAGCTGGTGCTAGTCGCTGCAAAACTTGACACCGAAGACAAG TTGAGGGCCGCAATGGTCGGGATGCTGGCCAACTTCTTGGGCTTCCGTATATATGGCATG CACAGTGAGCTATGGGGCGTGGTCCATGGGGCCACCGTCCTCTCCCCAACGGCTGTCTTT GGCACCCTGGCCTCTCTCTATCTGGGAGCCTTGGACCACACAGCTGACAGGCTACAGGCA ATCCTGGGTGTTCCTTGGAAGGACAAGAACTGCACCTCCCGGCTGGATGCGCACAAGGTC CTGTCTGCCCTGCAGGCTGTACAGGGCCTGCTAGTGGCCCAGGGCAGGGCTGATAGCCAG GCCCAGCTGCTGCTGTCCACGGTGGTGGGCGTGTTCACAGCCCCAGGCCTGCACCTGAAG CAGCCGTTTGTGCAGGGCCTGGCTCTCTATACCCCTGTGGTCCTCCCACGCTCTCTGGAC TTCACAGAACTGGATGTTGCTGCTGAGAAGATTGACAGGTTCATGCAGGCTGTGACAGGA TGGAAGACTGGCTGCTCCCTGATGGGAGCCAGTGTGGACAGCACCCTGGCTTTCAACACC TACGTCCACTTCCAAGGGAAGATGAAGGGCTTCTCCCTGCTGGCCGAGCCCCAGGAGTTC TGGGTGGACAACAGCACCTCAGTGTCTGTTCCCATGCTCTCTGGCATGGGCACCTTCCAG CACTGGAGTGACATCCAGGACAACTTCTCGGTGACTCAAGTGCCCTTCACTGAGAGCGCC TGCCTGCTGCTGATCCAGCCTCACTATGCCTCTGACCTGGACAAGGTGGAGGGTCTCACT TTCCAGCAAAACTCCCTCAACTGGATGAAGAAACTGTCTCCCCGGACCATCCACCTGACC ATGCCCCAACTGGTGCTGCAAGGATCTTATGACCTGCAGGACCTGCTCGCCCAGGCTGAG CTGCCCGCCATTCTGCACACCGAGCTGAACCTGCAAAAATTGAGCAATGACCGCATCAGG GTGGGGGAGGTGCTGAACAGCATTTTTTTTGAGCTTGAAGCGGATGAGAGAGAGCCCACA GAGTCTACCCAACAGCTTAACAAGCCTGAGGTCTTGGAGGTGACCCTGAACCGCCCATTC CTGTTTGCTGTGTATGATCAAAGCGCCACTGCCCTGCACTTCCTGGGCCGCGTGGCCAAC CCGCTGAGCACAGCATGA Clone variation with respect to NM_000029.3 1116 a=>g >OriGene 5' read for NM_000029 unedited
GTGTGCACTATTTTGTNAATACGACNCACTTATAGGGCGGCCGCGATTCGGCACGAGGTT GTTCTGGGTACTACAGCAGAAGGGTATGCGGAAGCGAGCACCCCAGTCTGAGATGGCTCC TGCCGGTGTGAGCCTGAGGGCCACCATCCTCTGCCTCCTGGCCTGGGCTGGCCTGGCTGC AGGTGACCGGGTGTACATACACCCCTTCCACCTCGTCATCCACAATGAGAGTACCTGTGA GCAGCTGGCAAAGGCCAATGCCGGGAAGCCCAAAGACCCCACCTTCATACCTGCTCCAAT TCAGGCCAAGACATCCCCTGTGGATGAAAAGGCCCTACAGGACCAGCTGGTGCTAGTCGC TGCAAAACTTGACACCGAAGACAAGTTGAGGGCCGCAATGGTCGGGATGCTGGCCAACTT CTTGGGCTTCCGTATATATGGCATGCACAGTGAGCTATGGGGCGTGGTCCATGGGGCCAC CGTTCTCTCCCCAACGGCTGTCTTTGGCACCCTGGCCTCTCTCTATCTGGGAGCCTTGGA CCACACAGCTGACAGGCTACAGGCAATCCTGGGTGTTCCTTGGAAGGACAAGAACTGCAC CTCCCCGGCTGGATGCGCACAAGGCCCCTGTCTGCCCTGCAGGCTGTACAGGGCCCTGCT AATGGCCCAAGGCAGGGCTGATAGCCAGGCCCAGCTGCTGCTGTCCACGTGGTGGGCGTG TTCACACTCCCAGCCTGCACTCGAACCACCGTTTGTGCAGGCCCTGCTTTCTATAACCCC TGAGGTCCTCCACCCTCTCTGGACTTCACAAAATGGATGTGCCGCTGACAAAAGGCAGGT TCATGCCCCCTGTGCACCGAAGGAAGACCGGCTGTTCCCTGATGGGACCACCGTGGAACA CACACCTGCCTT >OriGene 3' read for NM_000029 unedited
GGCAACTTTCCAGGGCCAGGNATAGCACTGGGGAGGGGTCACAGGGCAGCCACCCGGGAT CTGTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTT TTTGTGGCAAGACGTTTATTACTAACACAAGGGAGAAATAACCAGCTATTGTTCCGCATT CAAACAGAAATTCAGGTGCTTGCATCTTTCACGTATTGGTCAAAAATCACAAGCATCTGT GGAAAAAACTAAGGTATTACAGACACTACACGGAGGTCATGTTCTTACATTCAAGACACT AAATACAAACCGAAGGCAATGCAAAAATGTATACTTTAATTTTAAAACCCAATTTTTGTT CTCAACTTGAAAAGGGAACACTTTTTTGTTTCACAAACAAGCTGGTCGGTTGGAATTCTT TTTGGAACAGTAGTCCCGCGCTAAACACTGGTTCTTGCCTCCCCACCCCCATTCTCTAAA ATAAACCCAGCAAACTGGGAGGTGCATTTGTGCCGCTGCAGGCTTCTACTGCTCACTCCA TGCAGCACACTTAGACCAAGGAGAAACGGCTGCTTTCCAGCTCAAAGTCGACTATTAAAA GAAAAGGTGGGAGACTGGGGGTGACCATCCTGATTGTCCCCGGGGGGTGGTATCTGGCTG CTGGCCTTTGCCTCAAAGCCAAGGGCAAAAGCCTTGCAGCAACTGGGTTTTTGGGGGGCC TGGCTCATGCTGGCTAAAGGGGGTTGGCCCCCCGCCCACAAAAGCAGGGGCAATGGGGCT TTTTAATCTCCACACAGAAAGGGGGGGGGTTGGAGGCCCCCCCCAACCTAGGCTGTAAAA GCCGGGGGGGAAACCTTGGGGGGCCTCTTATAACGGTAAGCCAAAAAAGGCGG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_000029 |
| Insert Size | 2050 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_000029.2 |
| RefSeq Size | 2192 bp |
| RefSeq ORF | 1458 bp |
| Locus ID | 183 |
| UniProt ID | P01019 |
| Domains | SERPIN |
| Protein Families | Druggable Genome, Secreted Protein |
| Protein Pathways | Renin-angiotensin system |
| Gene Summary | The protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure, body fluid and electrolyte homeostasis, and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease. [provided by RefSeq, Nov 2019] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC203768 | AGT (Myc-DDK-tagged)-Human angiotensinogen (serpin peptidase inhibitor, clade A, member 8) (AGT) |
CNY 3,656.00 |
|
| RC203768L1 | Lenti ORF clone of Human angiotensinogen (serpin peptidase inhibitor, clade A, member 8) (AGT), Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC203768L2 | Lenti ORF clone of Human angiotensinogen (serpin peptidase inhibitor, clade A, member 8) (AGT), mGFP tagged |
CNY 5,890.00 |
|
| RC203768L3 | Lenti ORF clone of Human angiotensinogen (serpin peptidase inhibitor, clade A, member 8) (AGT), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC203768L4 | Lenti ORF clone of Human angiotensinogen (serpin peptidase inhibitor, clade A, member 8) (AGT), mGFP tagged |
CNY 5,890.00 |
|
| RG203768 | AGT (tGFP-tagged) - Human angiotensinogen (serpin peptidase inhibitor, clade A, member 8) (AGT) |
CNY 5,256.00 |
|
| SC322276 | AGT (untagged)-Human angiotensinogen (serpin peptidase inhibitor, clade A, member 8) (AGT) |
CNY 3,656.00 |
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