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PGP9.5 (UCHL1) (NM_004181) Human Untagged Clone
CAT＃: SC117505
UCHL1 (untagged)-Human ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) (UCHL1)
CNY 3,600.00
| Cited in 1 publication. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | HEL-117; HEL-S-53; NDGOA; PARK5; PGP 9.5; PGP9.5; PGP95; SPG79; Uch-L1 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC117505 sequence for NM_004181 edited (data generated by NextGen Sequencing)
ATGCAGCTCAAGCCGATGGAGATCAACCCCGAGATGCTGAACAAAGTGCTGTCCCGGCTG GGGGTCGCCGGCCAGTGGCGCTTCGTGGACGTGCTGGGGCTGGAAGAGGAGTCTCTGGGC TCGGTGCCAGCGCCTGCCTGCGCGCTGCTGCTGCTGTTTCCCCTCACGGCCCAGCATGAG AACTTCAGGAAAAAGCAGATTGAAGAGCTGAAGGGACAAGAAGTTAGTCCTAAAGTGTAC TTCATGAAGCAGACCATTGGGAATTCCTGTGGCACAATCGGACTTATTCACGCAGTGGCC AATAATCAAGACAAACTGGGATTTGAGGATGGATCAGTTCTGAAACAGTTTCTTTCTGAA ACAGAGAAAATGTCCCCTGAAGACAGAGCAAAATGCTTTGAAAAGAATGAGGCCATACAG GCAGCCCATGATGCCGTGGCACAGGAAGGCCAATGTCGGGTAGATGACAAGGTGAATTTC CATTTTATTCTGTTTAACAACGTGGATGGCCACCTCTATGAACTTGATGGACGAATGCCT TTTCCGGTGAACCATGGCGCCAGTTCAGAGGACACCCTGCTGAAGGACGCTGCCAAGGTC TGCAGAGAATTCACCGAGCGTGAGCAAGGAGAAGTCCGCTTCTCTGCCGTGGCTCTCTGC AAGGCAGCCTAA Clone variation with respect to NM_004181.4 >OriGene 5' read for NM_004181 unedited
ACAGTCAGATGTGTATCCGACTCATATGGGCGGCCGCGCAATCGGCACGAGGCCTCGTGC CGAATTCGGCACGAGGCTTCCCTAGGCTATTTCTGCCGGGCGCTCCGCGAAGATGCAGCT CAAGCCGATGGAGATCAACCCCGAGATGCTGAACAAAGTGCTGTCCCGGCTGGGGGTCGC CGGCCAGTGGCGCTTCGTGGACGTGCTGGGGCTGGAAGAGGAGTCTCTGGGCTCGGTGCC AGCGCCTGCCTGCGCGCTGCTGCTGCTGTTTCCCCTCACGGCCCAGCATGAGAACTTCAG GAAAAAGCAGATTGAAGAGCTGAAGGGACAAGAAGTTAGTCCTAAAGTGTACTTCATGAA GCAGACCATTGGGAATTCCTGTGGCACAATCGGACTTATTCACGCAGTGGCCAATAATCA AGACAAACTGGGATTTGAGGATGGATCAGTTCTGAAACAGTTTCTTTCTGAAACAGAGAA AATGTCCCCTGAAGACAGAGCAAAATGCTTTGAAAAGAATGAGGCCATACAGGCAGCCCA TGATGCCGTGGCACAGGAAGGCCAATGTCGGGTAGATGACAAGGTGAATTTCCATTTTAT TCTGTTTAACAACGTGGATGGCCACCTCTATGAACTTGATGGACGAATGCCTTTTCCGGT GAACCATGGCGCCAGTTCAGAGGACACCCTGCTGCAGGACGCTGCCAAGGTCTGCAGAGA ATTCACCGAGCGTGAGCAAGGAGACAGTCGCTTCTCTGCCGTGGCTCTCTGCAGGCAGCC TAATGCTCTGTGGGAGGGACTTTGCTGAGTTCCCCTCTTCCATTCACATGAAAATATATA CCCCCCCATGCAGTCTAGAATGCTTCAGTACTTGTGAAACACAGCTGATCTTCTGATCTG CAGACACGCATTCC >OriGene 3' read for NM_004181 unedited
AGGAGAGGCACTGGGGAGGGGTACAGGGATGCCACCCGGGATCTGTTCAGGAAACAGCTA TGACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT TTTTTTTTTTTTTTTTTTTTTTTTTTTTAACCCAAACAACAAAAAAGTTTTTTTCCTTTT GAGGACAAACAATTAAACCCCCTCCAAGGTTTTAACTTACAAACAAAAACCAAAGTTCCC CTTTAAAGCGTTAAATATCGGATACAAAACATACCCTGGGGAAAATGCTTCACCATTTGA AGCTCACACCACAATGGCCCAGGGGACAACTGGGCCCTCTGCTTGGGCTTAAATGCCTGG GTGGGGCTAAGGGGAAAGCCTTTCTACAAAACAAAAAAACAGCTGGGTTTCACAAGTACT GAAGCATTTTAAACTGGATGGGGGGGTATATATTTTCATGTTGAAGGGAAGAGGGGAAAT CACCAAAGTCCCTCCCACAGAGCATTAGGCTGCCTTGCAAAGAGCCACGGNAAAGAAGCG GACTTCTCCTTGCTCACGCTCGGGGAATTCTCTGAAAACTTGGNAGGGTTCTTAACAAGG TGTCCTCTGACTGGCCCATGGTTCACCGGAAAAGCATTCGCCCATCAGTTCATAAAGGGG CCATCCCCGTTGTTACAAATAAAATGAAATTCCCCTGTTTTTACCCAAATTGCCTTCTGT GCCACGGATATGGGCCTGCTGATGCCTATTCTTTAAAACATTTGCTTGGCTCAGGGATTT TCTTTGTTAAAAAAACTGTTAAAACGACCTCCTAAACCCATTTGTTTGATTTGCCACGGG AAAAACCCATGGCCCAGATTCCAAGGGCGCTTAAGAAACCTAAGACAACTTTGCCCTACT TTATTGCTTTCCGAACCCAGCGGCCGGAGGAAAAAAAAAGGCAGGGGGTTGGCAACCAAA TTTTCACCCAATTCAAGCCTGGCGACCACGAAATTTTT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_004181 |
| Insert Size | 1180 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_004181.3, NP_004172.2 |
| RefSeq Size | 1110 bp |
| RefSeq ORF | 672 bp |
| Locus ID | 7345 |
| UniProt ID | P09936 |
| Domains | Peptidase_C12 |
| Protein Families | Druggable Genome, Protease |
| Protein Pathways | Parkinson's disease |
| Gene Summary | The protein encoded by this gene belongs to the peptidase C12 family. This enzyme is a thiol protease that hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. This gene is specifically expressed in the neurons and in cells of the diffuse neuroendocrine system. Mutations in this gene may be associated with Parkinson disease.[provided by RefSeq, Sep 2009] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Potential of UCHL1 as biomarker for destruction of pancreatic beta cells
,Brackeva, B;De Punt, V;Kramer, G;Costa, O;Verhaeghen, K;Stangé, G;Sadones, J;Xavier, C;Aerts, JM;Gorus, FK;Martens, GA;,
J Proteomics
,PubMed ID 25638021
[UCHL1]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC201803 | UCHL1 (Myc-DDK-tagged)-Human ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) (UCHL1) |
CNY 3,600.00 |
|
| RC201803L1 | Lenti ORF clone of Human ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) (UCHL1), Myc-DDK-tagged |
CNY 6,000.00 |
|
| RC201803L2 | Lenti ORF clone of Human ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) (UCHL1), mGFP tagged |
CNY 6,000.00 |
|
| RC201803L3 | Lenti ORF clone of Human ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) (UCHL1), Myc-DDK-tagged |
CNY 6,000.00 |
|
| RC201803L4 | Lenti ORF clone of Human ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) (UCHL1), mGFP tagged |
CNY 6,000.00 |
|
| RG201803 | UCHL1 (tGFP-tagged) - Human ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) (UCHL1) |
CNY 5,200.00 |
