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CREB1 (NM_004379) Human Untagged Clone
CAT＃: SC117388
CREB1 (untagged)-Human cAMP responsive element binding protein 1 (CREB1), transcript variant A
CNY 2,400.00
CNY 6,270.00
| Cited in 2 publications. |
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热销推荐Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CREB; CREB-1 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC117388 sequence for NM_004379 edited (data generated by NextGen Sequencing)
ATGACCATGGAATCTGGAGCCGAGAACCAGCAGAGTGGAGATGCAGCTGTAACAGAAGCT GAAAACCAACAAATGACAGTTCAAGCCCAGCCACAGATTGCCACATTAGCCCAGGTATCT ATGCCAGCAGCTCATGCAACATCATCTGCTCCCACCGTAACTCTAGTACAGCTGCCCAAT GGGCAGACAGTTCAAGTCCATGGAGTCATTCAGGCGGCCCAGCCATCAGTTATTCAGTCT CCACAAGTCCAAACAGTTCAGATTTCAACTATTGCAGAAAGTGAAGATTCACAGGAGTCA GTGGATAGTGTAACTGATTCCCAAAAGCGAAGGGAAATTCTTTCAAGGAGGCCTTCCTAC AGGAAAATTTTGAATGACTTATCTTCTGATGCACCAGGAGTGCCAAGGATTGAAGAAGAG AAGTCTGAAGAGGAGACTTCAGCACCTGCCATCACCACTGTAACGGTGCCAACTCCAATT TACCAAACTAGCAGTGGACAGTATATTGCCATTACCCAGGGAGGAGCAATACAGCTGGCT AACAATGGTACCGATGGGGTACAGGGCCTGCAAACATTAACCATGACCAATGCAGCAGCC ACTCAGCCGGGTACTACCATTCTACAGTATGCACAGACCACTGATGGACAGCAGATCTTA GTGCCCAGCAACCAAGTTGTTGTTCAAGCTGCCTCTGGAGACGTACAAACATACCAGATT CGCACAGCACCCACTAGCACTATTGCCCCTGGAGTTGTTATGGCATCCTCCCCAGCACTT CCTACACAGCCTGCTGAAGAAGCAGCACGAAAGAGAGAGGTCCGTCTAATGAAGAACAGG GAAGCAGCTCGAGAGTGTCGTAGAAAGAAGAAAGAATATGTGAAATGTTTAGAAAACAGA GTGGCAGTGCTTGAAAATCAAAACAAGACATTGATTGAGGAGCTAAAAGCACTTAAGGAC CTTTACTGCCACAAATCAGATTAA Clone variation with respect to NM_004379.3 >OriGene 5' read for NM_004379 unedited
GGTCACATTTGTATACGACTCATATAGGGCGGCCGCGAATTCGCACGAGGCCTCAGTCGG CGGCGGCTGCTGCTGCCTGTGGCCCGGGCGGCTGGGAGAAGCGGAGTGTTGGTGAGTGAC GCGGCGGAGGTGTAGTTTGACGCGGTGTGTTACGTGGGGGAGAGAATAAAACTCCAGCGA GATCCGGGCCGTGAACGAAAGCAGTGACGGAGGAGCTTGTACCACCGGTAACTAAATGAC CATGGAATCTGGAGCCGAGAACCAGCAGAGTGGAGATGCAGCTGTAACAGAAGCTGAAAA CCAACAAATGACAGTTCAAGCCCAGCCACAGATTGCCACATTAGCCCAGGTATCTATGCC AGCAGCTCATGCAACATCATCTGCTCCCACCGTAACTCTAGTACAGCTGCCCAATGGGCA GACAGTTCAAGTCCATGGAGTCATTCAGGCGGCCCAGCCATCAGTTATTCAGTCTCCACA AGTCCAAACAGTTCAGATTTCAACTATTGCAGAAAGTGAAGATTCACAGGAGTCAGTGGA TAGTGTAACTGATTCCCAAAAGCGAAGGGAAATTCTTTCAAGGAGGCCTTCCTACAGGAA AATTTTGAATGACTTATCTTCTGATGCACCAGGAGTGCCAAGGATTGAAGAAGAGAAGTC TGAAGAGGAGACTTCAGCACCTGCCATCACCACTGTAACGGTGCCAACTCCAATTTACCA NACTAGCAGTGGACAGTATATTGCCATTACCCAGGGGAGGAGCATACAGCTGGCTAACAA TGGTACCGATGGGGTACAGGGCCCTGCAACATTAACCATGACCAATGCAGCAGCCACTCA GCCGGGTACTACCATTCTACAGTATGCACAGACCACTGATGGACAGCAGATCTTAATGCC CAGCACCCAGTTGT >OriGene 3' read for NM_004379 unedited
CTATGAACGCGGCCGCAATCTANAATCGAGTTTTTTTTTTTTTTTTTTAAGATAACTGTT AGATTTATCGAGCTTAGTGAATAAAATGAGTAACAATTAAAAGTGGTATTGAAAACAATG TATGATATACACAAATACAGACTGTTTTAATCAGGAATTAAAATTATAAAATGACAAAGG CTATACAGCATATTGGAAAGCTAAAGCAGAACTAATAACTACTCTTTTTACAAGAGAACA AAAAAATGTTTTGTAAGAATGACAATCCAAATATTGCAGTACAGCAGTCATTCAAATATG TCTGAAAATAACTTTCCTTGTGCACATCTAACACTGTACTTTTTATATCCTTACAACTTC TTTCATTTAAAAAATTCACTAGAGATTCTCTGTTAAATTGTTAATATGGAAAATATTTAA AATCAGTATTTTTCTACATGTAACATTTCATAAACAAATATATATCACTTTGCTTTATTT GACATCTTGAAGGCTTTCTTGGTGGTGGTATGTAAGTGCAATGGGCAACAGTAAATTAGA AATATCTTTTTACGTAAATGAGTGACAATATAAATATTTTTGAAGGTGAGGACAATAACA TTTATTTAAAAATCTTGTTATATAACTCAAGGGATTGGTTTACTGATCAGCATTTTACTA AGAATTTAGTACTAACTAAAATATGCTNTGTACTTTTATTTACTTTGCTTTAATTTAAAA TTCAAATACCATGCTTTGTCGTTCAGTTGGTTACTTCTTTTAATGTATTCAAAAATGTTG AACACATACAGAACTGAATAAAAAGCACAACTGCCCTATGGAAGAGCTGTATTAGTACAG AATGCTTTTAAGAACCAAGGACANATTNTCAGTNNTGNAGAAGACAACTACATAAAAGCC CTCAATTCATTCTAATCCTTCATACATGCTAAAGTCTTTTAGAGGGATGTCTTAACAACT TACTATTCCATGAGAGGGACACAGTCATTG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_004379 |
| Insert Size | 2690 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_004379.2, NP_004370.1 |
| RefSeq Size | 2964 bp |
| RefSeq ORF | 984 bp |
| Locus ID | 1385 |
| UniProt ID | P16220 |
| Domains | pKID, BRLZ |
| Protein Families | Druggable Genome, Transcription Factors |
| Protein Pathways | Antigen processing and presentation, Huntington's disease, Melanogenesis, Prostate cancer |
| Gene Summary | This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in several transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016] Transcript Variant: This variant (1, also known as A) lacks an alternate in-frame exon compared to variant 2. The resulting isoform (A) has the same N- and C-termini but is shorter compared to isoform B. Sequence Note: The RefSeq transcript and protein were derived from transcript and genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Mechanistic insights into COVID-19 by global analysis of the SARS-CoV-2 3CLpro substrate degradome
,null,
Cell Reports
,PubMed ID 34672947
[CREB1]
|
|
Regulation of the Hyaluronan Synthase 2 Gene by Convergence in Cyclic AMP Response Element-binding Protein and Retinoid Acid Receptor Signaling
,Katri M. Makkonen, Sanna Pasonen-Seppänen, Kari Törrönen, Markku I. Tammi, and Carsten Carlberg,
J. Biol. Chem., Jul 2009; 284: 18270 - 18281.
[CREB1]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC210577 | CREB1 (Myc-DDK-tagged)-Human cAMP responsive element binding protein 1 (CREB1), transcript variant A |
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| RC210577L1 | Lenti ORF clone of Human cAMP responsive element binding protein 1 (CREB1), transcript variant A, Myc-DDK-tagged |
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| RC210577L2 | Lenti ORF clone of Human cAMP responsive element binding protein 1 (CREB1), transcript variant A, mGFP tagged |
CNY 4,800.00 |
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| RC210577L3 | Lenti ORF clone of Human cAMP responsive element binding protein 1 (CREB1), transcript variant A, Myc-DDK-tagged |
CNY 4,800.00 |
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| RC210577L4 | Lenti ORF clone of Human cAMP responsive element binding protein 1 (CREB1), transcript variant A, mGFP tagged |
CNY 4,800.00 |
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| RG210577 | CREB1 (tGFP-tagged) - Human cAMP responsive element binding protein 1 (CREB1), transcript variant A |
CNY 4,000.00 |
