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EPS8 (NM_004447) Human Untagged Clone
CAT＃: SC117360
EPS8 (untagged)-Human epidermal growth factor receptor pathway substrate 8 (EPS8)
CNY 9,040.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | DFNB102 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC117360 sequence for NM_004447 edited (data generated by NextGen Sequencing)
ATGAATGGTCATATTTCTAATCATCCCAGTAGTTTTGGAATGTACCCATCTCAGATGAAT GGCTACGGATCATCACCTACCTTTTCCCAGACGGACAGAGAACATGGTTCAAAAACAAGT GCAAAGGCCCTTTATGAACAAAGGAAGAATTATGCACGGGACAGTGTCAGCAGTGTGTCA GATATATCTCAATACCGTGTTGAACACTTGACTACCTTTGTCCTGGATCGGAAAGATGCT ATGATCACTGTTGATGATGGAATAAGGAAATTGAAATTGCTTGATGCCAAGGGCAAAGTG TGGACTCAAGATATGATTCTTCAAGTGGATGACAGAGCTGTGAGCCTGATTGATTTAGAA TCAAAGAATGAACTGGAGAATTTTCCTTTAAACACAATCCAGCACTGCCAAGCTGTGATG CATTCATGCAGCTATGATTCAGTTCTTGCACTGGTGTGCAAAGAGCCAACCCAGAACAAG CCAGATCTTCATCTCTTCCAGTGTGATGAGGTTAAGGCAAACCTAATTAGTGAAGATATT GAAAGTGCAATCAGTGACAGTAAAGGAGGGAAACAGAAGAGGCGGCCCGACGCCCTGAGG ATGATTTCCAATGCAGACCCTAGTATACCGCCTCCACCCAGAGCTCCTGCCCCTGCGCCC CCTGGGACCGTCACCCAGGTGGATGTTAGAAGTCGAGTGGCAGCCTGGTCTGCATGGGCA GCCGACCAAGGGGACTTTGAGAAACCAAGGCAGTATCATGAGCAGGAAGAAACACCTGAG ATGATGGCAGCCCGCATTGACAGAGATGTGCAAATCTTAAACCACATTTTGGATGACATT GAATTTTTTATCACAAAACTCCAAAAAGCAGCAGAAGCATTTTCTGAGCTTTCTAAAAGG AAGAAAAACAAGAAAGGTAAAAGGAAAGGACCAGGAGAGGGTGTTTTAACGCTGCGGGCA AAACCTCCACCTCCTGATGAATTTCTTGACTGTTTCCAAAAGTTTAAACACGGATTTAAC CTTCTGGCCAAACTGAAGTCTCATATTCAGAATCCTAGTGCTGCAGATTTGGTTCACTTT TTGTTTACTCCATTAAATATGGTGGTGCAGGCAACAGGAGGTCCTGAACTAGCCAGTTCA GTACTTAGTCCCCTATTGAATAAGGACACAATTGATTTCTTAAATTATACTGTCAATGGT GATGAACGGCAGCTGTGGATGTCATTGGGAGGAACTTGGATGAAAGCCAGAGCAGAGTGG CCAAAAGAACAGTTTATTCCACCATATGTTCCACGATTCCGCAATGGCTGGGAGCCCCCA ATGCTGAACTTTATGGGAGCCACAATGGAACAAGATCTTTATCAACTGGCAGAATCTGTG GCAAATGTAGCAGAACATCAGCGCAAACAGGAAATAAAAAGATTATCCACAGAGCATTCC AGTGTATCAGAGTATCATCCAGCCGATGGCTATGCGTTCAGTAGCAACATTTACACAAGA GGATCCCACCTGGACCAAGGGGAAGCTGCTGTTGCTTTTAAGCCAACTTCTAATCGCCAT ATAGATAGAAATTATGAACCACTCAAAACACAACCCAAGAAATATGCCAAATCCAAGTAT GACTTTGTAGCAAGGAACAACAGTGAGCTCTCGGTTCTAAAGGATGATATTTTAGAGATA CTTGATGATCGGAAGCAATGGTGGAAAGTTCGAAATGCAAGTGGAGACTCTGGATTTGTG CCAAATAACATTTTGGATATTGTGAGACCTCCAGAATCTGGATTGGGGCGTGCTGATCCA CCTTATACTCATACTATACAGAAACAAAGGATGGAGTATGGCCCAAGACCAGCTGATACT CCCCCTGCTCCATCACCTCCTCCAACACCAGCTCCTGTTCCTGTTCCCCTTCCCCCTTCC ACTCCAGCACCTGTTCCTGTGTCAAAGGTCCCAGCAAATATAACACGTCAAAACAGCAGC TCCAGTGACAGTGGTGGCAGTATCGTGCGAGACAGCCAGAGACACAAACAACTTCCGGTG GACCGAAGGAAATCTCAGATGGAGGAAGTGCAAGATGAACTCATCCACAGACTGACCATT GGTCGGAGTGCCGCTCAGAAGAAATTCCATGTGCCACGGCAGAACGTGCCAGTTATCAAT ATCACTTACGACTCCACACCAGAGGATGTGAAGACGTGGTTACAGTCAAAGGGATTCAAC CCTGTGACTGTCAATAGTCTTGGAGTATTAAATGGTGCACAACTTTTCTCTCTCAATAAG GATGAACTGAGGACAGTCTGCCCTGAAGGGGCGAGAGTCTATAGCCAAATCACTGTACAA AAAGCTGCATTGGAGGATAGCAGTGGCAGCTCCGAGTTACAAGAAATTATGAGAAGACGA CAGGAAAAAATCAGTGCTGCCGCTAGTGATTCAGGAGTGGAATCTTTTGATGAAGGAAGC AGTCACTAA Clone variation with respect to NM_004447.5 >OriGene 5' read for NM_004447 unedited
TTTTGTATACGACTCACTATAGGGCGGCCGCGATTCGGCACGAGGCGAGGGCGGATCCGA GAACACACNAAGTGAAAGACACAATGAATGGTCATATTTCTAATCATCCCAGTAGTTTTG GAATGTACCCATCTCAGATGAATGGCTACGGATCATCACCTACCTTTTCCCAGACGGACA GAGAACATGGTTCAAAAACAAGTGCAAAGGCCCTTTATGAACAAAGGAAGAATTATGCAC GGGACAGTGTCAGCAGTGTGTCAGATATATCTCAATACCGTGTTGAACACTTGACTACCT TTGTCCTGGATCGGAAAGATGCTATGATCACTGTTGATGATGGAATAAGGAAATTGAAAT TGCTTGATGCCAAGGGCAAAGTGTGGACTCAAGATATGATTCTTCAAGTGGATGACAGAG CTGTGAGCCTGATTGATTTAGAATCAAAGAATGAACTGGAGAATTTTCCTTTAAACACAA TCCAGCACTGCCAAGCTGTGATGCATTCATGCAGCTATGATTCAGTTCTTGCACTGGTGT GCAAAGAGCCAACCCAGAACAAGCCAGATCTTCATCTCTTCCAGTGTGATGAGGTTAAGG CAAACCTAATTAGTGAAGATATTGAAAGTGCAATCAGTGACAGTAAAGGAGGGAAACAGA AGAGGCGGCCCGACGCCCTGAGGATGATTTCCAATGCAGACCCTAGTATACCGCCTCCAC CCAGAGCTCCTGCCCCTGCGCCCCCTGGGACCGTCACCCAGGTGGATGTTAGAAGTCGAG TGGCAGCCTGGTCTGCATGGGCAGCCGACCAAGGGGACTTTGAGAAACCAGGCAGTATCA TGAGCAGGAAGAAACACCTGAGAGATGGCAGCCCGCATGACAGAGAGTGCAAATCTTAAC ACATTTGG >OriGene 3' read for NM_004447 unedited
GCGGCACGCAATCTAGAATCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT TTTTTTTTTTTTTTTTTTTTTTTTAAACAAACAAAAAATCCTGTTTTTTGGAAACTTTCC AGTTGCCTTTTGGGAAAAGGGCCCTTTGAAAATTAAGGAATCTAAATAATTTCTCTAAAG GATTTATGTAAAAATATCCAACTTTTTTACAAAACATGGGTTTTTTTTTGGGGAAAAAAT ATACCTTTTAAGGCCAAAATTGGGGTTCCCAAAAAAAACATTGGGGGAAGGGTAGGTTTT TTTCTTTTCTTTATGGGGAATCTTTCACAGGATTAAAATTTGGGGAAATTAAGGGCTTTT TTTTCCCAAAAATCCTTGCCCCAAATAAACCCATAAAAGGGCCCCCCTTCCTTTTAACCC CCCATATAAACATTCAAAACGGGGGCTTTCTTTAACCAAAATCCTGGATGGCCCCCCAAG GCAAACTCCTTCCTTTGCTAAATTTGGAAAAAACATGACCTTTTTCCCATTGGGGCTTTC TCATTTTTAAAAACCCGGTTTCCTTATTAGGCAAATTTTAACCTAATTCAAATTCCCCCC TTTCCAGGGGGTTGCATTCAACAAACCCATGACAAACGGGCTTGAAAATGCCCCATAAAT TTATATTGGCATGCCCAAGGGATGGGTGGCCTTTACAGTTCATTCAAAGGTTTTAATTTT TTTTTAAACGGGCGGCCTTAAAAACTTTAAATAAACCTAATATTCCCCCCCTTGACTTGC CAAAAAGAGACTTAAGTAGCCGAGGCTTCCCCCAGTGAGCTTGCCCTGAAGACAAACCCC TTTTCCGGCAAATCGAACCTGTTAATTTTGATTTGGACACATTGGGCTTTGTGAGGATAT CTCCCCCTTAAACATTCTNTTTCCCGGGATGGGAAAAAATTCGCATTG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_004447 |
| Insert Size | 3670 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | A True clone. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_004447.4, NP_004438.3 |
| RefSeq Size | 3912 bp |
| RefSeq ORF | 2469 bp |
| Locus ID | 2059 |
| UniProt ID | Q12929 |
| Domains | SH3, PID |
| Protein Families | Druggable Genome |
| Gene Summary | This gene encodes a member of the EPS8 family. This protein contains one PH domain and one SH3 domain. It functions as part of the EGFR pathway, though its exact role has not been determined. Highly similar proteins in other organisms are involved in the transduction of signals from Ras to Rac and growth factor-mediated actin remodeling. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008] |
Documents
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| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC205300 | EPS8 (Myc-DDK-tagged)-Human epidermal growth factor receptor pathway substrate 8 (EPS8) |
CNY 9,032.00 |
|
| RC205300L1 | Lenti ORF clone of Human epidermal growth factor receptor pathway substrate 8 (EPS8), Myc-DDK-tagged |
CNY 11,432.00 |
|
| RC205300L2 | Lenti ORF clone of Human epidermal growth factor receptor pathway substrate 8 (EPS8), mGFP tagged |
CNY 5,890.00 |
|
| RC205300L3 | Lenti ORF clone of Human epidermal growth factor receptor pathway substrate 8 (EPS8), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC205300L4 | Lenti ORF clone of Human epidermal growth factor receptor pathway substrate 8 (EPS8), mGFP tagged |
CNY 5,890.00 |
|
| RG205300 | EPS8 (tGFP-tagged) - Human epidermal growth factor receptor pathway substrate 8 (EPS8) |
CNY 10,632.00 |
