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COX7A2L (NM_004718) Human Untagged Clone
CAT＃: SC117225
COX7A2L (untagged)-Human cytochrome c oxidase subunit VIIa polypeptide 2 like (COX7A2L), nuclear gene encoding mitochondrial protein
CNY 1,200.00
CNY 2,950.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | COX7AR; COX7RP; EB1; SCAF1; SCAFI; SIG81 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC117225 sequence for NM_004718 edited (data generated by NextGen Sequencing)
ATGTACTACAAGTTTAGTGGCTTCACGCAGAAGTTGGCAGGAGCATGGGCTTCGGAGGCC TATAGCCCGCAGGGATTAAAGCCTGTGGTTTCCACAGAAGCACCACCTATCATATTTGCC ACACCAACTAAACTGACCTCCGATTCCACAGTGTATGATTATGCTGGGAAAAACAAAGTT CCAGAGCTACAAAAGTTTTTCCAGAAAGCTGATGGTGTGCCCGTCTACCTGAAACGAGGC CTGCCTGACCAAATGCTTTACCGGACCACCATGGCGCTGACTGTGGGAGGGACCATCTAC TGCCTGATCGCCCTCTACATGGCTTCGCAGCCCAAAAACAAATGA Clone variation with respect to NM_004718.2 >OriGene 5' read for NM_004718 unedited
AAGTCAGAATTTGTATACGACTCATATAGGGCGGCCGCGAATTCGCACGAGGGTCCTTCT CTGGGGCGGTCGCGTTGGCAGCGGATGCGGGAAGCCGGACTCTGGGCGTCATGTACTACA AGTTTAGTGGCTTCACGCAGAAGTTGGCAGGAGCATGGGCTTCGGAGGCCTATAGCCCGC AGGGATTAAAGCCTGTGGTTTCCACAGAAGCACCACCTATCATATTTGCCACACCAACTA AACTGACCTCCGATTCCACAGTGTATGATTATGCTGGGAAAAACAAAGTTCCAGAGCTAC AAAAGTTTTTCCAGAAAGCTGATGGTGTGCCCGTCTACCTGAAACGAGGCCTGCCTGACC AAATGCTTTACCGGACCACCATGGCGCTGACTGTGGGAGGGACCATCTACTGCCTGATCG CCCTCTACATGGCTTCGCAGCCCAAAAACAAATGAGTTAGGCTGCAGAGGACTGGTTTGT TTTTTGGCATAAACCCTTTGAAGTTCCTTTTTCATTGTTAAATTAAAATTTTTTTTTTTA CTTGGATGGCTTAACATTTTTGCAAGAAAAATAGGAAGATATGAAGATGATGTTNTTGGT TTGTTTATGAAATGCATATGGCTTGTCAGAGCTCATTCGACAGTTAAAGCCATTGTTTAA AGAAATGGTGCTTTGCTCTGTGTTTGTGCTCCTGATTTCCCTGGAGGTTCTGGATGAAGG CTGAACACAGGCTTGTTAATGTCAGTCTGTGCTGAGGACCTCAGGACNTTGAGGTTGCAT TTTTGAGCATGGGGTGCANGAGCCTTTCTGGATTTTGGATGTGGCTATNGGAAAGAACAC AGAGCAAGGTCATGTGCATGAATGGAGGAGTTTGAGTTAGTCCCTCGGGGGATTTTTTCC ATTTTGCAGTAAATGTTAAATTAATGTACCTGCCTCTATT >OriGene 3' read for NM_004718 unedited
CGGCCGCAATCTAAAGTCGAGTTTTTTTTTTTTTTTTTTAATTTTTCATTCATGTATTTA TTCCACAGTCAAAATAAATCAAAATTTAAAGCTATAACATTTTTAAAAGATAAAGGAGAA TTTGTGGCACAGCTGCATTAACAAAACAGACACCAGTCTAAAGTGCAACACTAAACAGGT ATTCTCTGTTCCCACGGTGGAATAATTACACATAAGATTTCACTAAAGATAGGAGATGAG GCAAATAACCCTTTGAAATTACCTGCCCAACAAATAGAGGCAGGCTACATTAATTTAACA TTTTACTGCAAAATGGAAAAAATCCCCGAGGTGACTAACTCAAACTCCTCATTTCATGCA CATGACCTTGGCTTCTGTGTTCTTTCCATAGCCACATCCAAATCCAGAAAGGCTCCTGCA CCCCATGCTCAAAAATGCAACCTCAAGTCCCTGAGGTCCTCAGCACAGACTGACATTAAC AAGCCTGTGTTCAGCCTTCATCCAGAACCTCCAGGGAAATCAGGAGCACAAACACAGAGC AAAGCACCATTTCTTTAAACAATGGCTTTAACTGTCGAATGAGCTCTGACAAGCCATATG CATTTCATAAACAAACCAAAACATCATCTTCATATCTTCCTATTTTTCTTGCAAAAATGT TAAGCCATCCAANGTAAAAAAAAAATTTAATTTAACAATGAAAAAGGAACTTNCAAGGGT TTATGCCAAAAAACAAACCAGTCCTCTGCAGCCTAACTCATTTGTTTTTGGGGCTGCGAA GCCATGTAGAGGGCGATCAGGCAGTAGATGGTCCCCTCCACAGTCAGCGCCATGGTGGTC CCGTTAAGCATTTGGTCAGGCAGCCCTCGTTTCAGTACACGGCCACACCATCAAGCTTCT GGAAACACTTTTGTAGCTCTGGAACTCTGGTTTTCCACCCATATCTACCCTGGGGATCGG AGTCATTTTATTTGTGTGGCAAAATGATAGGCGTGCTCCT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_004718 |
| Insert Size | 1110 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_004718.2, NP_004709.2 |
| RefSeq Size | 1145 bp |
| RefSeq ORF | 345 bp |
| Locus ID | 9167 |
| UniProt ID | O14548 |
| Domains | COX7a |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Alzheimer's disease, Cardiac muscle contraction, Huntington's disease, Oxidative phosphorylation, Parkinson's disease |
| Gene Summary | Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein similar to polypeptides 1 and 2 of subunit VIIa in the C-terminal region, and also highly similar to the mouse Sig81 protein sequence. This gene is expressed in all tissues, and upregulated in a breast cancer cell line after estrogen treatment. It is possible that this gene represents a regulatory subunit of COX and mediates the higher level of energy production in target cells by estrogen. Several transcript variants, some protein-coding and others non-protein coding, have been found for this gene. [provided by RefSeq, Jan 2016] Transcript Variant: This variant (1) represents the predominant transcript and encodes the longest isoform (a). Variants 1 and 2 both encode the same isoform (a). |
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC202697 | COX7A2L (Myc-DDK-tagged)-Human cytochrome c oxidase subunit VIIa polypeptide 2 like (COX7A2L), nuclear gene encoding mitochondrial protein |
CNY 1,200.00 |
|
| RC202697L3 | Lenti ORF clone of Human cytochrome c oxidase subunit VIIa polypeptide 2 like (COX7A2L), nuclear gene encoding mitochondrial protein, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC202697L4 | Lenti ORF clone of Human cytochrome c oxidase subunit VIIa polypeptide 2 like (COX7A2L), nuclear gene encoding mitochondrial protein, mGFP tagged |
CNY 5,890.00 |
|
| RG202697 | COX7A2L (tGFP-tagged) - Human cytochrome c oxidase subunit VIIa polypeptide 2 like (COX7A2L), nuclear gene encoding mitochondrial protein |
CNY 2,800.00 |
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