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SH3BP5 (NM_004844) Human Untagged Clone
CAT＃: SC117138
SH3BP5 (untagged)-Human SH3-domain binding protein 5 (BTK-associated) (SH3BP5), transcript variant 1
CNY 3,656.00
CNY 7,220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | SAB; SH3BP-5 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC117138 sequence for NM_004844 edited (data generated by NextGen Sequencing)
ATGGACGCGGCACTGAAGCGGAGCCGCTCGGAGGAGCCAGCCGAAATCCTGCCGCCTGCC CGGGACGAGGAGGAGGAGGAGGAAGAGGGGATGGAGCAGGGGCTGGAGGAGGAAGAAGAG GTGGATCCCCGGATCCAGGGAGAACTGGAGAAGTTAAATCAGTCCACGGATGATATCAAC AGACGGGAGACTGAACTTGAGGATGCTCGTCAGAAGTTCCGCTCTGTTCTGGTTGAAGCA ACGGTGAAACTGGATGAACTGGTGAAGAAAATTGGCAAAGCTGTGGAAGACTCCAAGCCC TACTGGGAGGCACGGAGGGTGGCGAGGCAGGCTCAGCTGGAAGCTCAGAAAGCCACGCAG GACTTCCAGAGGGCCACAGAGGTGCTCCGTGCCGCCAAGGAGACCATCTCCCTGGCCGAG CAGCGGCTGCTGGAGGATGACAAGCGGCAGTTCGACTCCGCCTGGCAGGAGATGCTGAAT CACGCCACTCAGAGGGTCATGGAGGCGGAGCAGACCAAGACCAGGAGCGAGCTGGTGCAT AAGGAGACGGCAGCCAGGTACAATGCCGCCATGGGCCGCATGCGACAGCTGGAGAAGAAA CTCAAGAGAGCCATCAACAAGTCCAAGCCTTATTTTGAACTCAAGGCAAAGTACTATGTG CAGCTCGAGCAACTGAAAAAGACTGTGGATGACCTGCAGGCCAAACTGACCCTGGCAAAA GGCGAGTACAAGATGGCCCTGAAGAACCTGGAGATGATCTCAGATGAGATCCACGAGCGG CGGCGCTCCAGTGCCATGGGGCCTCGGGGATGCGGTGTTGGTGCTGAGGGCAGCAGCACA TCTGTGGAGGATCTGCCAGGGAGCAAACCTGAGCCTGATGCCATTTCTGTGGCCTCGGAG GCCTTTGAAGATGACAGCTGTAGCAACTTTGTGTCTGAAGATGACTCGGAAACCCAGTCC GTGTCCAGCTTTAGTTCAGGACCAACAAGCCCGTCTGAGATGCCTGACCAGTTCCCTGCG GTTGTGAGGCCTGGCAGCCTGGATCTGCCCAGCCCTGTGTCCCTGTCAGAGTTTGGGATG ATGTTCCCAGTGTTGGGCCCTCGAAGTGAATGCAGCGGGGCCTCCTCCCCTGAATGTGAA GTAGAACGAGGAGACAGGGCAGAAGGGGCAGAGAATAAAACAAGTGACAAAGCCAACAAC AACCGGGGCCTCAGCAGTAGCAGTGGCAGTGGTGGCAGCAGTAAGAGCCAAAGCAGCACC TCCCCTGAGGGCCAGGCCTTGGAGAACCGGATGAAGCAGCTCTCCCTACAGTGCTCAAAG GGAAGAGATGGAATTATTGCTGACATAAAAATGGTGCAGATTGGCTGA Clone variation with respect to NM_004844.3 >OriGene 5' read for NM_004844 unedited
NGGTTCAAATTTGTATACGACTCCTATAGGGCGGCCGCGAATTCGCACGAGGGCGCGGCG CGCGTGCCGGCTGCCTGCATGGACGCGGCACTGAAGCGGAGCCGCTCGGAGGAGCCAGCC GAAATCCTGCCGCCTGCCCGGGACGAGGAGGAGGAGGAGGAAGAGGGGATGGAGCAGGGG CTGGAGGAGGAAGAAGAGGTGGATCCCCGGATCCAGGGAGAACTGGAGAAGTTAAATCAG TCCACGGATGATATCAACAGACGGGAGACTGAACTTGAGGATGCTCGTCAGAAGTTCCGC TCTGTTCTGGTTGAAGCAACGGTGAAACTGGATGAACTGGTGAAGAAAATTGGCAAAGCT GTGGAAGACTCCAAGCCCTACTGGGAGGCACGGAGGGTGGCGAGGCAGGCTCAGCTGGAA GCTCAGAAAGCCACGCAGGACTTCCAGAGGGCCACAGAGGTGCTCCGTGCCGCCAAGGAG ACCATCTCCCTGGCCGAGCAGCGGCTGCTGGAGGATGACAAGCGGCAGTTCGACTCCGCC TGGCAGGAGATGCTGAATCACGCCACTCAGAGGGTCATGGAGGCGGAGCAGACCAAGACC AGGAGCGAGCTGGTGCATAAGGAGACGGCAGCCAGGTACAATGCCGCCATGGGCCGCATG CGACAGCTGGAGAAGAAACTCAAGAGAGCCATCAACAAGTCCAAGCCTTATTTTGAACTC AAGGCAAAGTACTATGTGCAGCTCGAGCAACTGAAAAAGACTGTGGATGACCTGCAGGCC AAACTGACCCTGGCANAAGCGAGTACAAGATGGCCCTGNAGAACCTGGAGATGATCTCAN ATGAGATCCACGAGCGGCGGGCGCTCAGTGCCATGGGGCCTCCGNGATGCGGTGTTTGTG C >OriGene 3' read for NM_004844 unedited
CGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTCTCAAGCCGTTTTTATTAC ACTTAGTGTATTAAGACAAGTACAAAATAACCTTGTAATTAAGATACTGTATCAGTCAAA AAAGAAGTCACTATTGTATGAAGAGATTTACAAATGACTAAAATATACAGGCTGTGACAG AATTAACAGTTTGAAAGAGGGTTGCTTTTTTCTTTTAGAAATGCTAAATTTTCTTAACAA GACAAAAATACAGTGCTCTAAATATGCATTACCATGAAAACGTTAAAGAAAAGCAGTCTT AACACTTAACTACTATTAACAGCCTTTGCCAACACATGCCTGCCTACTCCCTTTCCTAAC TTTAAAGAACTGTTTCCTCTAAGGAATACTAGTGCAGCATAACCCTTAAATAATTTCATT TATTTTTAAAGTTACAACCTACAGAGAAATTAACATCTTGTCAATCTAATAACAGTGGCA ACCATTCTTCACATGCACTTCTCTTAGAATAAATCCCCTTGGCTGGCAGGATAAGGCTTA TGCTGTAGAACCTTCTCCCCCACAGCCACAAATCCCCTTCTATAAGTCCCTCCTACCCTC ATCCCCCCGCATCCCCACTGGCATTCACCTTTTCCACCCCAANAAGTGCAGCTCATGGTA GCCTTCTAGAAAATGGTTTTAATGGGTATCCCAGCATACACGCTTTTTTAAAAGCCCCCT CTGAACACCAGAGGGTGGTGAAAATGAATNGTGTTCTTGGATTTTTTTTTTTTTTTTTTA ACCTCACTGGTCAAAAAATGTGCTCTTAAACTTGAGTTTTGCTTTGGGGGGGGTTTCTTT CTTTTCATTANATTCGNGGGAAAAGGGGAGAGACATTCCTTTTTCATACAACTGAGGTGA GAGAGAAGAAANCAGCTGTGCCCCATTTGCCTGTTTCCANCATTTTCACTTTGTTTTTAT G |
| Restriction Sites | NotI-NotI |
| ACCN | NM_004844 |
| Insert Size | 2890 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_004844.2, NP_004835.1 |
| RefSeq Size | 2906 bp |
| RefSeq ORF | 1278 bp |
| Locus ID | 9467 |
| UniProt ID | O60239 |
| Gene Summary | Functions as guanine nucleotide exchange factor (GEF) with specificity for RAB11A and RAB25 (PubMed:26506309, PubMed:30217979). Inhibits the auto- and transphosphorylation activity of BTK. Plays a negative regulatory role in BTK-related cytoplasmic signaling in B-cells. May be involved in BCR-induced apoptotic cell death.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a). |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC203999 | SH3BP5 (Myc-DDK-tagged)-Human SH3-domain binding protein 5 (BTK-associated) (SH3BP5), transcript variant 1 |
CNY 3,656.00 |
|
| RC203999L1 | Lenti ORF clone of Human SH3-domain binding protein 5 (BTK-associated) (SH3BP5), transcript variant 1, Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC203999L2 | Lenti ORF clone of Human SH3-domain binding protein 5 (BTK-associated) (SH3BP5), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RC203999L3 | Lenti ORF clone of Human SH3-domain binding protein 5 (BTK-associated) (SH3BP5), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC203999L4 | Lenti ORF clone of Human SH3-domain binding protein 5 (BTK-associated) (SH3BP5), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RG203999 | SH3BP5 (tGFP-tagged) - Human SH3-domain binding protein 5 (BTK-associated) (SH3BP5), transcript variant 1 |
CNY 5,256.00 |
|
| SC317747 | SH3BP5 (untagged)-Human SH3-domain binding protein 5 (BTK-associated) (SH3BP5), transcript variant 1 |
CNY 7,220.00 |
