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KRIT1 (NM_004912) Human Untagged Clone
CAT＃: SC117060
KRIT1 (untagged)-Human KRIT1, ankyrin repeat containing (KRIT1), transcript variant 2
CNY 5,400.00
CNY 7,220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CAM; CCM1 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_004912, the custom clone sequence may differ by one or more nucleotides
ATGGGAAATCCAGAAAACATAGAAGATGCATATGTTGCTGTTATTCGTCCAAAGAATACTGCCAGTCTCA ATTCTCGGGAATACAGAGCTAAGTCATATGAAATTTTGTTGCATGAAGTTCCCATTGAAGGACAGAAAAA AAAGAGAAAGAAAGTTTTATTGGAAACGAAACTTCAAGGCAACAGTGAAATAACACAAGGCATATTGGAT TACGTAGTAGAAACCACCAAACCAATTTCTCCTGCAAACCAGGGTATCAGAGGAAAACGAGTTGTACTAA TGAAAAAATTTCCTCTGGATGGAGAGAAGATGGGCAGAGAAGCATCATTATTTATTGTTCCATCAGTTGT CAAAGATAATACTAAATACACATATACCCCAGGATGCCCAATTTTTTACTGCTTACAAGATATTATGCGA GTCTGTAGTGAATCCAGTACTCATTTTGCTACACTTACAGCAAGGATGTTAATAGCCTTGGATAAGTGGT TAGATGAACGTCATGCACAATCTCACTTTATTCCAGCTTTATTCCGACCTTCTCCTCTTGAGCGGATAAA AACTAATGTCATAAATCCTGCATATGCTACTGAATCAGGTCAGACAGAAAACTCACTACATATGGGCTAT AGTGCACTAGAAATAAAGAGTAAAATGTTAGCCCTAGAGAAAGCAGATACCTGTATTTACAACCCTTTGT TTGGATCAGATCTTCAGTATACAAATCGGGTAGATAAAGTGGTAATAAATCCATACTTTGGTCTAGGAGC TCCAGACTACTCAAAAATCCAAATACCTAAACAGGAAAAATGGCAGAGAAGCATGAGCAGTGTCACAGAA GACAAGGAACGACAGTGGGTAGATGATTTTCCTCTCCACCGAAGCGCCTGTGAAGGAGATTCAGAATTAC TAAGCCGTCTTCTCAGTGAAAGATTTTCAGTCAACCAGTTAGATAGTGACCACTGGGCACCCATTCATTA TGCATGCTGGTATGGAAAAGTTGAGGCCACTCGCATATTGTTAGAGAAAGGAAAGTGCAATCCAAACCTT TTAAATGGACAACTTAGTTCTCCTCTTCATTTTGCTGCTGGAGGAGGACATGCTGAAATAGTACAGATTC TCCTAAACCACCCAGAAACGGATAGACATATAACAGACCAACAAGGAAGATCTCCATTAAATATTTGTGA AGAAAACAAACAAAACAACTGGGAAGAAGCTGCAAAATTGTTGAAGGAAGCAATTAACAAACCATATGAA AAAGTTCGAATATACAGAATGGATGGGTCATATCGTTCTGTTGAATTGAAGCATGGAAATAATACCACAG TGCAGCAGATAATGGAAGGAATGCGTCTCTCTCAAGAAACTCAGCAATATTTCACTATATGGATTTGTTC AGAAAACCTCAGCCTTCAACTCAAACCATATCATAAACCCTTGCAACATGTTCGTGACTGGCCAGAAATA CTTGCTGAATTGACTAATCTGGATCCTCAAAGGGAAACACCTCAGCTTTTTCTAAGAAGAGATGTGAGAC TTCCCTTGGAAGTTGAAAAACAGATTGAAGACCCACTAGCTATTCTTATTCTCTTTGATGAAGCCAGATA TAATTTATTGAAGGGCTTTTATACAGCTCCTGATGCTAAGCTGATAACATTGGCAAGTCTGCTTTTGCAA ATAGTCTATGGAAATTATGAGAGTAAAAAACACAAGCAAGGTTTCCTAAATGAAGAAAATCTAAAATCCA TCGTACCTGTTACCAAACTGAAAAGTAAGGCACCTCACTGGACAAATCGCATACTTCATGAATACAAGAA TCTCAGTACAAGTGAAGGTGTCAGTAAAGAAATGCATCACCTTCAGCGCATGTTCTTACAGAATTGCTGG GAAATTCCTACTTATGGAGCAGCATTTTTCACAGGACAGATATTTACAAAGGCAAGCCCCAGCAATCATA AAGTCATCCCTGTGTATGTAGGAGTGAATATAAAAGGACTTCATCTCCTCAACATGGAAACTAAGGCTTT ACTCATCAGTCTTAAGTATGGTTGTTTTATGTGGCAATTGGGAGATACTGATACTTGTTTTCAGATCCAT AGCATGGAAAATAAAATGAGCTTTATAGTACATACAAAACAGGCTGGTCTCGTGGTAAAACTGTTAATGA AGCTAAATGGACAGTTAATGCCCACTGAAAGAAATTCATGA >OriGene 5' read for NM_004912 unedited
GGTTCACCAATTTGTAATACGACCTCACTATAGGCGGCCCGCGAATCGGCACGAGGCCTC GTGCCGAATTCGGCACGAGGCACAAGGCATATTGGATTACGTAGTAGAAACCACCAAACC AATTTCTCCTGCAAACCAGGGTATCAGAGGAAAACGAGTTGTACTAATGAAAAAATTTCC TCTGGATGGAGAGAAGATGGGCAGAGAAGCATCATTATTTATTGTTCCATCAGTTGTCAA AGATAATACTAAATACACATATACCCCAGGATGCCCAATTTTTTACTGCTTACAAGATAT TATGCGAGTCTGTAGTGAATCCAGTACTCATTTTGCTACACTTACAGCAAGGATGTTAAT AGCCTTGGATAAGTGGTTAGATGAACGTCATGCACAATCTCACTTTATTCCAGCTTTATT CCGACCTTCTCCTCTTGAGCGGATAAAAACTAATGTCATAAATCCTGCATATGCTACTGA ATCAGGTCAGACAGAAAACTCACTACATATGGGCTATAGTGCACTAGAAATAAAGAGTAA AATGTTAGCCCTAGAGAAAGCAGATACCTGTATTTACAACCCTTTGTTTGGATCAGATCT TCAGTATACAAATCGGGTAGATAAAGTGGTAATAAATCCATACTTTGGTCTAGGAGCTCC AGACTACTCANAAATCCAAATACCTAAACAGGAAAAATGGCAGAGAAGCATGAGCAGTGT CACAGAAGACAAGGAACGACAGTGGGTAGATGATTTTCCTCTCCACCCGAGCGCCTGTGA ANGAGATTCAGAATTACTAAGCCGTCTTCTCAGTGAAAGATTTCAGTCAACCAGNTAGAT AGTGACCCACTGGCACCCATTCTTATGCATGCCTGTATGGAAAAAGTTGAGCCACTCGCA TATTGTTAGAGAAAGGAC >OriGene 3' read for NM_004912 unedited
CGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTGAGATGGAGTCTTGCTGTGT CACCCAGGCTAGCGTGCCGTGGTGCAATCTCGGCTCACTACAACCTCCACCTCCCGGGTT TAAGCGATCTCCCACCTTGGCCTCCCTAGTAGCTAGGATTATAGGCGCCCGCCACCACAC CCAGCTAATTTTTGCATTTCTGTAGAGACAGGGTTCCACCATGTTGGCACATCCTGGTAT TGAACTCCTGACTTCAGGTGATACCGACTGCCACAAACCCCATAAACCGCCGAAATTCCA CGAATGCCTTCTTCCCCCCCCTCCCTTATTCTTCCCCCGCCACCCAAACCCCCCCCCCAC CCCCGAGTTCTTCTACCTAATCCGCTTCCCAATTCTCCTCCCCCCTCTCCCCCCTCTCAC TCTTCCCACCCACACTCCTTCCCCCCCATCCCCCTACCCCCCTTTTTTCCCCCCACCCCA CTTACTCCCCCCACCCCCCCCTCTCCCCATTTTTCTCATTCTTCTCACTCCCCTTCACTT CCTTATCTCCAACCACTTCCCACCCCCCCCCTCCCTTCTACCCCCCCCCCCCCCACACAT ACCTCCCATCTTTATTTCTCTATCACTCCCCCCCCCTCCACCCTGCTGATAACCCACCAG TTTACTTCCCTACTCTCTCTTCTTCCTTTCCCCCCCCCTCCTCACCATTTTACTTCTCCC CTCCCCCCACTCCCTCCCACCCTTCTAATTCCTAAATCAACCCGAGTCCGCCGCGCCACC CCCCCTCTCCCTCCTTTCCCTTTTTCCCCACTTCACCCACTCCCCCCCATGACCTCCTAT CCTCCCCTCCCCCCCTTCCTCCTCCTTTACTCCCCGCACCCCAACCCCCATGCCCCCTCC CACCTCATACTCTCCTTTCTTCCCCCTCCCCT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_004912 |
| Insert Size | 2600 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_004912.3, NP_004903.2 |
| RefSeq Size | 4870 bp |
| RefSeq ORF | 2211 bp |
| Locus ID | 889 |
| UniProt ID | O00522 |
| Domains | B41, ANK |
| Protein Families | Druggable Genome |
| Gene Summary | This gene encodes a protein containing four ankyrin repeats, a band 4.1/ezrin/radixin/moesin (FERM) domain, and multiple NPXY sequences. The encoded protein is localized in the nucleus and cytoplasm. It binds to integrin cytoplasmic domain-associated protein-1 alpha (ICAP1alpha), and plays a critical role in beta1-integrin-mediated cell proliferation. It associates with junction proteins and RAS-related protein 1A (Rap1A), which requires the encoded protein for maintaining the integrity of endothelial junctions. It is also a microtubule-associated protein and may play a role in microtubule targeting. Mutations in this gene result in cerebral cavernous malformations. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2009] Transcript Variant: This variant (2) lacks the 5' exon but has an alternate segment in the 5' UTR, as compared to variant 1. Variants 1-4 encode the same isoform (1). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC211686 | KRIT1 (Myc-DDK-tagged)-Human KRIT1, ankyrin repeat containing (KRIT1), transcript variant 2 |
CNY 3,990.00 |
|
| RC211686L3 | Lenti-ORF clone of KRIT1 (Myc-DDK-tagged)-Human KRIT1, ankyrin repeat containing (KRIT1), transcript variant 2 |
CNY 5,890.00 |
|
| RC211686L4 | Lenti-ORF clone of KRIT1 (mGFP-tagged)-Human KRIT1, ankyrin repeat containing (KRIT1), transcript variant 2 |
CNY 5,890.00 |
|
| RG211686 | KRIT1 (tGFP-tagged) - Human KRIT1, ankyrin repeat containing (KRIT1), transcript variant 2 |
CNY 4,370.00 |
