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GRK3 (NM_005160) Human Untagged Clone
CAT＃: SC116916
ADRBK2 (untagged)-Human adrenergic, beta, receptor kinase 2 (ADRBK2)
CNY 7,568.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ADRBK2; BARK2 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_005160 edited
ATGGCGGACCTGGAGGCTGTGCTGGCCGATGTCAGTTACCTGATGGCCATGGAGAAGAGC AAGGCGACCCCGGCCGCCCGCGCCAGCAAGAGGATCGTCCTGCCGGAGCCCAGTATCCGG AGTGTGATGCAGAAGTACCTTGCAGAGAGAAATGAAATAACCTTTGACAAGATTTTCAAT CAGAAAATTGGTTTCTTGCTATTTAAAGATTTTTGTTTGAATGAAATTAATGAAGCTGTA CCTCAGGTGAAGTTTTATGAAGAGATAAAGGAATATGAAAAACTTGATAATGAGGAAGAC CGCCTTTGCAGAAGTCGACAAATTTATGATGCCTACATCATGAAGGAACTTCTTTCCTGT TCACATCCTTTCTCAAAGCAAGCTGTAGAACACGTACAAAGTCATTTATCCAAGAAACAA GTGACATCAACTCTTTTTCAGCCATACATAGAAGAAATTTGTGAAAGCCTTCGAGGTGAC ATTTTTCAAAAATTTATGGAAAGTGACAAGTTCACTAGATTTTGTCAGTGGAAAAACGTT GAATTAAATATCCATTTGACCATGAATGAGTTCAGTGTGCATAGGATTATTGGACGAGGA GGATTCGGGGAAGTTTATGGTTGCAGGAAAGCAGACACTGGAAAAATGTATGCAATGAAA TGCTTAGATAAGAAGAGGATCAAAATGAAACAAGGAGAAACATTAGCCTTAAATGAAAGA ATCATGTTGTCTCTTGTCAGCACAGGAGACTGTCCTTTCATTGTATGTATGACCTATGCC TTCCATACCCCAGATAAACTCTGCTTCATCCTGGATCTGATGAACGGGGGCGATTTGCAC TACCACCTTTCACAACACGGTGTGTTCTCTGAGAAGGAGATGCGGTTTTATGCCACTGAA ATCATTCTGGGTCTGGAACACATGCACAATCGGTTTGTTGTCTACAGAGATTTGAAGCCA GCAAATATTCTCTTGGATGAACATGGACACGCAAGAATATCAGATCTTGGTCTTGCCTGC GATTTTTCCAAAAAGAAGCCTCATGCGAGTGTTGGCACCCATGGGTACATGGCTCCCGAG GTGCTGCAGAAGGGGACGGCCTATGACAGCAGTGCCGACTGGTTCTCCCTGGGCTGCATG CTTTTCAAACTTCTGAGAGGTCACAGCCCTTTCAGACAACATAAAACCAAAGACAAGCAT GAAATTGACCGAATGACACTCACCGTGAATGTGGAACTTCCAGACACCTTCTCTCCTGAA CTGAAGTCCCTTTTGGAGGGCTTGCTTCAGCGAGACGTTAGCAAGCGGCTGGGCTGTCAC GGAGGCGGCTCACAGGAAGTAAAAGAGCACAGCTTTTTCAAAGGTGTTGACTGGCAGCAT GTCTACTTACAAAAGTACCCACCACCCTTGATTCCTCCCCGGGGAGAAGTCAATGCTGCT GATGCCTTTGATATTGGCTCATTTGATGAAGAGGATACCAAAGGGATTAAGCTACTTGAT TGCGACCAAGAACTCTACAAGAACTTCCCTTTGGTCATCTCTGAACGCTGGCAGCAAGAA GTAACGGAAACAGTTTATGAAGCAGTAAATGCAGACACAGATAAAATCGAGGCCAGGAAG AGAGCTAAAAATAAGCAACTTGGCCACGAAGAAGATTACGCTCTGGGGAAGGACTGTATT ATGCACGGGTACATGCTGAAACTGGGAAACCCATTTCTGACTCAGTGGCAGCGTCGCTAT TTTTACCTCTTTCCAAATAGACTTGAATGGAGAGGAGAGGGAGAGTCCCGGCAAAATTTA CTGACAATGGAACAGATTCTCTCTGTGGAAGAAACTCAAATTAAAGACAAAAAATGCATT TTGTTCAGAATAAAAGGAGGGAAACAATTTGTCTTGCAATGTGAGAGTGATCCAGAGTTT GTGCAGTGGAAGAAAGAGTTGAACGAAACCTTCAAGGAGGCCCAGCGGCTATTGCGTCGT GCCCCGAAGTTCCTCAACAAACCTCGGTCAGGTACTGTGGAGCTCCCAAAGCCATCCCTC TGTCACAGAAACAGCAACGGCCTCTAG >OriGene 5' read for NM_005160 unedited
AAATCTTGGATTTGTATACGACTTATATAGGCGGCCGCGCAATTCGCACGAGGCCAAAGC TCGCCAACATGGCGGACCTGGAGGCTGTGCTGGCCGATGTCAGTTACCTGATGGCCATGG AGAAGAGCAAGGCGACCCCGGCCGCCCGCGCCAGCAAGAGGATCGTCCTGCCGGAGCCCA GTATCCGGAGTGTGATGCAGAAGTACCTTGCAGAGAGAAATGAAATAACCTTTGACAAGA TTTTCAATCAGAAAATTGGTTTCTTGCTATTTAAAGATTTTTGTTTGAATGAAATTAATG AAGCTGTACCTCAGGTGAAGTTTTATGAAGAGATAAAGGAATATGAAAAACTTGATAATG AGGAAGACCGCCTTTGCAGAAGTCGACAAATTTATGATGCCTACATCATGAAGGAACTTC TTTCCTGTTCACATCCTTTCTCAAAGCAAGCTGTAGAACACGTACAAAGTCATTTATCCA AGAAACAAGTGACATCAACTCTTTTATAGCCATACATAGAAGAAATTTGTGAAAGCCTTC GAGGTGACATTTTTCAAAAATTTATGGAAAGTGACAAGTTCACTAGATTTTGTCAGTGGA AAAACGTTGAATTAAATATCCATTTGACCATGAATGAGTTCAGTGTGCATAGGATTATTG GACGAGGAGGATTCGGGGAAGTTTATGGTTGCAGGANAGCAGACACTGGAAAAATGTATG CAATGAAATGCTTAGATAAGAAGAGGATCANAATGAAACAAGGAGAAACATTAGCCTTAA ATGANAGAATCATGTTGTCTCTTGTCAGCACNAGAGACTGTCNCTTCATTGTATGTATGA CCTATGCCTTNCATACCCCAGATAACTCTGCTTCATCCTGGATCTGATGAACGGGGGCGA TTTGCACTACCACCTTTCACACAN >OriGene 3' read for NM_005160 unedited
GCGGCACGCAATCTAGTATCGAGTTTTTTTTTTTTTTTTTTAAGACTGATGACATGGNGG GATTTCGCTGGTTCTCATAACCCAGCATCTATTTGGGGGTATCAGTGGGGCCTGGAGGCA GTGGGAGAAAACAAACTTCACAGGGCAGATGCTGCTGGGACCAGGAAAAAGGCTTCATGC CCTAAGGTCCTCACTGTCGTACAGCCCAGTGCAAAGTATCATTCATTCATGACAGATGCA TGACGACATGAAAGTCAATATACACAGTTAACCCATTTTGACACATTCATTCCTCAGCAT TTTTTCAATACAATTCATCTGAAATTATACTAAGACATAAAACAGACCTGCTTTTGTACA TCCATTACTGATATGTCTCCCAGGGTCAGGCAGAAGGAACCAGAATGACTGTCACACAAC TGCTAATTGTCGAGACCTGAGACGGACTCACCCATGAGTGCTCCTGCATGCCAGGTACTG CTTGTCGACTCGTGCACACTGGACTCAAAGACTTTTGAAAACTGCTCTTGCCCCTGAAAC CTAAAACTCCACGGCCTGTCCTTCAGAATCACTGTAAATCTTTCCAATGATGGACGGATG AATGCCTTCAATGATTAGTTAATCCCATACACTTGGATAGTACGTGTCCGTCATTCCCAC CTGGCTGAGGGGGCCCCGGAACAGACTGGTCAGAGGCAGGGCAGTCATGTGGGTGCGGCT CCCAGAGGAGGCCCAATGCAGAATATCTTCAACTTTAATATATCAGAAATATCTTCACTT TAACCCCAGACAAGAATAGTTGCGAGTGCCATAGTAACCACTGGGCTCTCCATCCCCAGC AGTTGACCAAGACTANAAATCACGTGACTGACGGATATGTGCATGCTTAGGCATCTGTAC CCAACTGACATCTTAAATTCTCCTGCGAGTCTAGAAGTGTTGATTCAGACTAAN |
| Restriction Sites | NotI-NotI |
| ACCN | NM_005160 |
| Insert Size | 3370 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_005160.2, NP_005151.1 |
| RefSeq Size | 3628 bp |
| RefSeq ORF | 2067 bp |
| Locus ID | 157 |
| UniProt ID | P35626 |
| Domains | RGS, pkinase, S_TK_X, TyrKc, PH, S_TKc |
| Protein Families | Druggable Genome, Protein Kinase |
| Protein Pathways | Chemokine signaling pathway, Endocytosis, Olfactory transduction |
| Gene Summary | The beta-adrenergic receptor kinase specifically phosphorylates the agonist-occupied form of the beta-adrenergic and related G protein-coupled receptors. Overall, the beta adrenergic receptor kinase 2 has 85% amino acid similarity with beta adrenergic receptor kinase 1, with the protein kinase catalytic domain having 95% similarity. These data suggest the existence of a family of receptor kinases which may serve broadly to regulate receptor function. [provided by RefSeq, Jul 2008] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC215129 | ADRBK2 (Myc-DDK-tagged)-Human adrenergic, beta, receptor kinase 2 (ADRBK2) |
CNY 7,560.00 |
|
| RC215129L1 | Lenti ORF clone of Human adrenergic, beta, receptor kinase 2 (ADRBK2), Myc-DDK-tagged |
CNY 9,960.00 |
|
| RC215129L2 | Lenti ORF clone of Human adrenergic, beta, receptor kinase 2 (ADRBK2), mGFP tagged |
CNY 9,120.00 |
|
| RC215129L3 | Lenti ORF clone of Human adrenergic, beta, receptor kinase 2 (ADRBK2), Myc-DDK-tagged |
CNY 9,120.00 |
|
| RC215129L4 | Lenti ORF clone of Human adrenergic, beta, receptor kinase 2 (ADRBK2), mGFP tagged |
CNY 9,960.00 |
|
| RG215129 | ADRBK2 (tGFP-tagged) - Human adrenergic, beta, receptor kinase 2 (ADRBK2) |
CNY 9,160.00 |
|
| SC116917 | ADRBK2 (untagged)-ORIGENE UNIQUE VARIANT 1 of Human adrenergic, beta, receptor kinase 2 (ADRBK2) |
CNY 13,300.00 |
|
| SC323529 | ADRBK2 (untagged)-Kinase deficient mutant (K220M) of Human adrenergic, beta, receptor kinase 2 (ADRBK2) |
CNY 7,568.00 |
