United States
Germany
Japan
United Kingdom
China
ZBTB48 (NM_005341) Human Untagged Clone
CAT＃: SC116763
ZBTB48 (untagged)-Human zinc finger and BTB domain containing 48 (ZBTB48)
CNY 5,048.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | HKR3; pp9964; TZAP; ZNF855 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC116763 sequence for NM_005341 edited (data generated by NextGen Sequencing)
ATGGACGGCTCCTTCGTCCAGCACAGTGTGAGGGTTCTGCAGGAGCTCAACAAGCAGCGG GAGAAGGGCCAGTACTGCGACGCCACTCTGGACGTGGGGGGCCTGGTGTTTAAGGCACAC TGGAGTGTCCTTGCCTGCTGCAGTCACTTTTTCCAGAGCCTCTACGGGGATGGCTCAGGG GGCAGTGTCGTCCTCCCTGCTGGCTTCGCTGAGATCTTTGGCCTCTTGTTGGACTTTTTC TACACTGGTCACCTCGCTCTCACCTCAGGGAACCGGGATCAGGTGCTCCTGGCAGCCAGG GAGTTGCGAGTGCCAGAGGCCGTAGAGCTGTGCCAGAGCTTCAAGCCCAAAACTTCAGTG GGACAGGCAGCAGGTGGCCAGAGTGGGCTGGGGCCCCCTGCCTCCCAGAATGTGAACAGC CACGTCAAGGAGCCGGCAGGCTTGGAAGAAGAGGAAGTTTCGAGGACTCTGGGTCTAGTC CCCAGGGATCAGGAGCCCAGAGGCAGTCATAGTCCTCAGAGGCCCCAGCTCCATTCCCCA GCTCAGAGTGAGGGCCCCTCCTCCCTCTGTGGGAAACTGAAGCAGGCCTTGAAGCCTTGT CCCCTTGAGGACAAGAAACCCGAGGACTGCAAAGTGCCCCCAAGGCCCTTAGAGGCTGAA GGTGCCCAGCTGCAGGGCGGCAGTAATGAGTGGGAAGTGGTGGTTCAAGTGGAGGATGAT GGGGATGGCGATTACATGTCTGAGCCTGAGGCTGTGCTGACCAGGAGGAAGTCAAATGTA ATCCGAAAGCCCTGTGCAGCTGAGCCAGCCCTGAGCGCGGGCTCCCTAGCAGCTGAGCCT GCTGAGAACAGAAAAGGTACAGCGGTGCCGGTCGAATGCCCCACATGTCATAAAAAGTTC CTCAGCAAATATTATCTAAAAGTCCACAACAGGAAACATACTGGGGAGAAACCCTTTGAG TGTCCCAAATGTGGGAAGTGTTACTTTCGGAAGGAGAACCTCCTGGAGCATGAAGCCCGG AATTGCATGAACCGCTCGGAACAGGTCTTCACGTGCTCTGTGTGCCAGGAGACATTCCGC CGAAGGATGGAGCTGCGGGTGCACATGGTGTCTCACACAGGGGAGATGCCCTACAAGTGT TCCTCCTGCTCCCAGCAGTTCATGCAGAAGAAGGACTTGCAGAGCCACATGATCAAACTT CATGGAGCCCCCAAGCCCCATGCATGCCCCACCTGTGCCAAGTGCTTCCTGTCTCGGACA GAGCTGCAGCTGCATGAAGCTTTCAAGCACCGTGGTGAGAAGCTGTTTGTGTGTGAGGAG TGTGGGCACCGGGCCTCGAGCCGGAATGGCCTGCAGATGCACATCAAGGCCAAGCACAGG AATGAGAGGCCACACGTATGTGAGTTCTGCAGCCACGCCTTCACCCAAAAGGCCAATCTC AACATGCACCTGCGCACACACACGGGTGAGAAGCCCTTCCAGTGCCACCTCTGTGGCAAG ACCTTCCGAACCCAAGCCAGCCTGGACAAGCACAACCGCACCCACACCGGGGAAAGGCCC TTCAGTTGCGAGTTCTGTGAACAGCGCTTCACTGAGAAGGGGCCCCTCCTGAGGCACGTG GCCAGCCGCCATCAGGAGGGCCGGCCCCACTTCTGCCAGATATGCGGCAAGACCTTCAAA GCCGTGGAGCAACTGCGTGTGCACGTCAGACGGCACAAGGGGGTGAGGAAGTTTGAGTGC ACCGAGTGTGGCTACAAGTTTACCCGACAGGCCCACCTGCGGAGGCACATGGAGATCCAC GACCGGGTAGAGAACTACAACCCGCGGCAGCGCAAGCTCCGCAACCTGATCATCGAGGAC GAGAAGATGGTGGTGGTGGCGCTGCAGCCGCCTGCAGAGCTGGAGGTGGGCTCGGCGGAG GTCATTGTGGAGTCCCTGGCCCAGGGCGGCCTGGCCTCCCAGCTCCCCGGCCAGAGACTG TGTGCAGAGGAGAGCTTCACCGGCCCAGGTGTCCTGGAGCCCTCCCTCATCATCACAGCT GCTGTCCCCGAGGACTGTGACACATAG Clone variation with respect to NM_005341.2 >OriGene 5' read for NM_005341 unedited
AGATTTTGTATACGACTACTATAGGCGGCNCGCGAATTCGCACGAGGGAGTCTCCGCACT GTCGGCGGGGTACGCATAGCCGGGCACTAGGAGCTTTCTCTTGCATACCCTCGCTTAGGC TGGCCGGGGTGTCACTTCTGCCTCCCTGCCCTCCAGACCATGGACGGCTCCTTCGTCCAG CACAGTGTGAGGGTTCTGCAGGAGCTCAACAAGCAGCGGGAGAAGGGCCAGTACTGCGAC GCCACTCTGGACGTGGGGGGCCTGGTGTTTAAGGCACACTGGAGTGTCCTTGCCTGCTGC AGTCACTTTTTCCAGAGCCTCTACGGGGATGGCTCAGGGGGCAGTGTCGTCCTCCCTGCT GGCTTCGCTGAGATCTTTGGCCTCTTGTTGGACTTTTTCTACACTGGTCACCTCGCTCTC ACCTCAGGGAACCGGGATCAGGTGCTCCTGGCAGCCAGGGAGTTGCGAGTGCCAGAGGCC GTAGAGCTGTGCCAGAGCTTCAAGCCCAAAACTTCAGTGGGACAGGCAGCAGGTGGCCAG AGTGGGCCTGGGGCCCCCTGCCTCCCAGAATGTGAACAGCCACGTCAAGGAGCCGGCAGG CTTGGAAGAAGAGGAAGTTTCGAGGACTCTGGGTCTAGTCCCCAGGGATCAGGAGCCCAG AGGCAGTCATAGTCCTCAGAGGCCCCAGCTCCATTCCCCAGCTCAGAAGTGAGGGCCCCT CCTNCCTCTGTGGGGAACTGNNAGCANGCCTTTGAGCCTTGTCCNCTTTTGAGACAGAAC CCGAGACTGCAAAGTGCCCCCAAGCCCTAAGGCTCTGAGGTGCCCACTGCAGCGCATATG TGNAAAAAAANGGGGTAATGAGAGAAAANNANNNNNNNNNNNGAAATNNTNNNNNACNNA GAGGTTGTCTCCCAAGAGGAATTAATGTTATCCAAAACCTGTCAATGACCACCTTTAACC GGCTCCTACACTAACTGCTGAACANAAGGACCCCGA >OriGene 3' read for NM_005341 unedited
NAATCNTTGNNACCGCGGCCGCAATTCTANGTCGAGNTTTTTTTTTTTTTTTTTTTTTGT CCAAAGCCACTCGGTTTATTGAGGGGTGGGGCCAAGTGGGCTCTGGTGGCCAGAATGGGC TATGTGTCACAGTCCTCGGGGACAGCAGCTGTGATGATGAGGGAGGGCTCCAGGACACCT GGGCCGGTGAAGCTCTCCTCTGCACACAGTCTCTGGCCGGGGAGCTGGGAGGCCAGGCCG CCCTGGGCCAGGGACTCCACAATGACCTCCGCCGAGCCCACCTCCAGCTCTGCAGGCGGC TGCAGCGCCACCACCACCATCTTCTCGTCCTCGATGATCAGGTTGCGGAGCTTGCGCTGC CGCGGGTTGTAGTTCTCTACCCGGTCGTGGATCTCCATGTGCCTCCGCAGGTGGGCCTGT CGGGTAAACTTGTAGCCACACTCGGTGCACTCAAACTTCCTCACCCCCTTGTGCCGTCTG ACGTGCACACGCAGTTGCTCCACGGCTTTGAAGGTCTTGCCGCATATCTGGCAGAAGTGG GGCCGGCCCTCCTGATGGCGGCTGGCCACGTGCCTCAGGAGGGGCCCCTTCTCAGTGAAG CGCTGTTCACAGAACTCGCAACTGAAGGGCCTTTCCCCGGTGTGGGTGCCCGTTGTGCTT GCCCAGGCTGCCTTTGGGGTCCGAAGGGCCTTGCCCCCGAGGTGGCACCTGGAAGGGCCT CTCACCCGGGGGGCGTGCGCCAGTGCCTGTCTGAGATCGCCCCTTTTGGGTGAAGGCCGT GCTGCCCAAATTCCATCCGCGGGGCCTCCCCCTTCTGGGCTTGGCCTCCAATGGCCCTCT CCAGGCCATTCCGTTTTGGGCCCGGTGGCCCACCTTTTAACCCCAAACACTTCTTCCCCG TGCCTTGACCCTTTATCCACTGCACCCTTTCCCAG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_005341 |
| Insert Size | 2400 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_005341.1, NP_005332.1 |
| RefSeq Size | 2289 bp |
| RefSeq ORF | 2067 bp |
| Locus ID | 3104 |
| UniProt ID | P10074 |
| Domains | BTB, zf-C2H2 |
| Protein Families | Transcription Factors |
| Gene Summary | Telomere-binding protein that acts as a regulator of telomere length (PubMed:28500257, PubMed:28082411). Directly binds the telomeric double-stranded 5'-TTAGGG-3' repeat (PubMed:28500257, PubMed:28082411). Preferentially binds to telomeres that have a low concentration of shelterin complex and acts as a regulator of telomere length by initiating telomere trimming, a process that prevents the accumulation of aberrantly long telomeres (PubMed:28082411). Also acts as a transcription regulator that binds to promoter regions (PubMed:7969177, PubMed:24382891, PubMed:28500257). Regulates expression of a small subset of genes, including MTFP1 (PubMed:28500257). Regulates expression the J and/or S elements in MHC II promoter (PubMed:7969177). Acts as a negative regulator of cell proliferation by specifically activating expression of ARF, a tumor suppressor isoform of CDKN2A (PubMed:24382891).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2 and 3 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC202057 | ZBTB48 (Myc-DDK-tagged)-Human zinc finger and BTB domain containing 48 (ZBTB48) |
CNY 5,040.00 |
|
| RC202057L3 | Lenti ORF clone of Human zinc finger and BTB domain containing 48 (ZBTB48), Myc-DDK-tagged |
CNY 7,700.00 |
|
| RC202057L4 | Lenti ORF clone of Human zinc finger and BTB domain containing 48 (ZBTB48), mGFP tagged |
CNY 7,700.00 |
|
| RG202057 | ZBTB48 (tGFP-tagged) - Human zinc finger and BTB domain containing 48 (ZBTB48) |
CNY 6,640.00 |
|
| SC322351 | ZBTB48 (untagged)-Human zinc finger and BTB domain containing 48 (ZBTB48) |
CNY 5,048.00 |
