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VEGFC (NM_005429) Human Untagged Clone
CAT＃: SC116730
VEGFC (untagged)-Human vascular endothelial growth factor C (VEGFC)
CNY 5,488.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | Flt4-L; LMPH1D; LMPHM4; VRP |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_005429 edited
GGCACCAGGGGAGAGGGACCAGGAGGGGCCCGCGGCCTCGCAGGGGCGCCCGCGCCCCCA CCCCTGCCCCCGCCAGCGGACCGGTCCCCCACCCCCGGTCCTTCCACCATGCACTTGCTG GGCTTCTTCTCTGTGGCGTGTTCTCTGCTCGCCGCTGCGCTGCTCCCGGGTCCTCGCGAG GCGCCCGCCGCCGCCGCCGCCTTCGAGTCCGGACTCGACCTCTCGGACGCGGAGCCCGAC GCGGGCGAGGCCACGGCTTATGCAAGCAAAGATCTGGAGGAGCAGTTACGGTCTGTGTCC AGTGTAGATGAACTCATGACTGTACTCTACCCAGAATATTGGAAAATGTACAAGTGTCAG CTAAGGAAAGGAGGCTGGCAACATAACAGAGAACAGGCCAACCTCAACTCAAGGACAGAA GAGACTATAAAATTTGCTGCAGCACATTATAATACAGAGATCTTGAAAAGTATTGATAAT GAGTGGAGAAAGACTCAATGCATGCCACGGGAGGTGTGTATAGATGTGGGGAAGGAGTTT GGAGTCGCGACAAACACCTTCTTTAAACCTCCATGTGTGTCCGTCTACAGATGTGGGGGT TGCTGCAATAGTGAGGGGCTGCAGTGCATGAACACCAGCACGAGCTACCTCAGCAAGACG TTATTTGAAATTACAGTGCCTCTCTCTCAAGGCCCCAAACCAGTAACAATCAGTTTTGCC AATCACACTTCCTGCCGATGCATGTCTAAACTGGATGTTTACAGACAAGTTCATTCCATT ATTAGACGTTCCCTGCCAGCAACACTACCACAGTGTCAGGCAGCGAACAAGACCTGCCCC ACCAATTACATGTGGAATAATCACATCTGCAGATGCCTGGCTCAGGAAGATTTTATGTTT TCCTCGGATGCTGGAGATGACTCAACAGATGGATTCCATGACATCTGTGGACCAAACAAG GAGCTGGATGAAGAGACCTGTCAGTGTGTCTGCAGAGCGGGGCTTCGGCCTGCCAGCTGT GGACCCCACAAAGAACTAGACAGAAACTCATGCCAGTGTGTCTGTAAAAACAAACTCTTC CCCAGCCAATGTGGGGCCAACCGAGAATTTGATGAAAACACATGCCAGTGTGTATGTAAA AGAACCTGCCCCAGAAATCAACCCCTAAATCCTGGAAAATGTGCCTGTGAATGTACAGAA AGTCCACAGAAATGCTTGTTAAAAGGAAAGAAGTTCCACCACCAAACATGCAGCTGTTAC AGACGGCCATGTACGAACCGCCAGAAGGCTTGTGAGCCAGGATTTTCATATAGTGAAGAA GTGTGTCGTTGTGTCCCTTCATATTGGAAAAGACCACAAATGAGCTAAGATTGTACTGTT TTCCAGTTCATCGATTTTCTATTATGGAAAACTGTGTTGCCACAGTAGAACTGTCTGTGA ACAGAGAGACCCTTGTGGGTCCATGCTAACAAAGACAAAAGTCTGTCTTTCCTGAACCAT GTGGATAACTTTACAGAAATGGACTGGAGCTCATCTGCAAAAGGCCTCTTGTAAAGACTG GTTTTCTGCCAATGACCAAACAGCCAAGATTTTCCTCTTGTGATTTCTTTAAAAGAATGA CTATATAATTTATTTCCACTAAAAATATTGTTTCTGCATTCATTTTTATAGCAACAACAA TTGGTAAAACTCACTGTGATCAATATTTTTATATCATGCAAAATATGTTTAAAATAAAAT GAAAATTGTATTAT >OriGene 5' read for NM_005429 unedited
GATTTTGGTATACGACTCACTATAGGGCGGCCGCGAATTCGGCACCAGGGGNAAAGGGAC CAGGAGGGGCCCGCGGCCTCGCAGGGGCGCCCGCGCCCCCACCCCTGCCCCCGCCAGCGG ACCGGTCCCCCACCCCCGGTCCTTCCACCATGCACTTGCTGGGCTTCTTCTCTGTGGCGT GTTCTCTGCTCGCCGCTGCGCTGCTCCCGGGTCCTCGCGAGGCGCCCGCCGCCGCCGCCG CCTTCGAGTCCGGACTCGACCTCTCGGACGCGGAGCCCGACGCGGGCGAGGCCACGGCTT ATGCAAGCAAAGATCTGGAGGAGCAGTTACGGTCTGTGTCCAGTGTAGATGAACTCATGA CTGTACTCTACCCAGAATATTGGAAAATGTACAAGTGTCAGCTAAGGAAAGGAGGCTGGC AACATAACAGAGAACAGGCCAACCTCAACTCAAGGACAGAAGAGACTATAAAATTTGCTG CAGCACATTATAATACAGAGATCTTGAAAAGTATTGATAATGAGTGGAGAAAGACTCAAT GCATGCCACGGGAGGTGTGTATAGATGTGGGGAAGGAGTTTGGAGTCGCGACAAACACCT TCTTTAAACCTCCATGTGTGTCCGTCTACAGATGTGGNGGTTGCTGCAATAGTGAGGGGC TGCAGTGCATGAACACCAGCACGAGCTACCTCAGNCAGACGTTATTTGAAATTACAGTGC CTCTCTCTCAGGGCCCANACCAGTANNNCATCAGTTTGCCAATCACACTTCCTGCCGATG CATGTCTAACTGGATGNTACAGACAGNTCATTNCATATTAGACCGTCCTGNCAGCACACT ACCCAGTGTCAGGCAGCGACAAGACTGCCCCACATTACATGGGATAATACTCTGCCGAGC CTGCTCAGAGAATTATTTTTCCTCGAGCTGAGAGACCACAGAGGATCCTGACTCGTGACA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_005429 |
| Insert Size | 1900 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_005429.2, NP_005420.1 |
| RefSeq Size | 2076 bp |
| RefSeq ORF | 1260 bp |
| Locus ID | 7424 |
| UniProt ID | P49767 |
| Domains | PDGF, CXCXC |
| Protein Families | Druggable Genome, Secreted Protein |
| Protein Pathways | Bladder cancer, Cytokine-cytokine receptor interaction, Focal adhesion, mTOR signaling pathway, Pancreatic cancer, Pathways in cancer, Renal cell carcinoma |
| Gene Summary | The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. The encoded protein promotes angiogenesis and endothelial cell growth, and can also affect the permeability of blood vessels. The proprotein is further cleaved into a fully processed form that can bind and activate VEGFR-2 and VEGFR-3 receptors. [provided by RefSeq, Apr 2014] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
E2F1 promotes angiogenesis through the VEGF-C/VEGFR-3 axis in a feedback loop for cooperative induction of PDGF-B
,null,
Journal of Molecular Cell Biology
,PubMed ID 24014887
[VEGFC]
|
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Resources
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| RC209451L3 | Lenti ORF clone of Human vascular endothelial growth factor C (VEGFC), Myc-DDK-tagged |
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