United States
Germany
Japan
United Kingdom
China
LNK (SH2B3) (NM_005475) Human Untagged Clone
CAT＃: SC116715
SH2B3 (untagged)-Human SH2B adaptor protein 3 (SH2B3)
CNY 4,288.00
CNY 7,220.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | IDDM20; LNK |
| Vector | pCMV6-XL6 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC116715 sequence for NM_005475 edited (data generated by NextGen Sequencing)
ATGAACGGGCCTGCCCTGCAGCCCTCCTCGCCCTCTTCCGCGCCCTCAGCCTCCCCGGCG GCGGCCCCGCGGGGCTGGAGCGAGTTCTGTGAGTTGCACGCCGTAGCGGCGGCCCGGGAG CTGGCCCGCCAGTACTGGCTGTTCGCCCGGGAGCATCCGCAGCACGCGCCGCTGCGCGCC GAGCTGGTGTCGCTGCAGTTCACCGACCTCTTCCAGCGCTACTTCTGCCGCGAGGTGCGC GACGGACGGGCGCCGGGCCGCGACTACCGGGACACAGGCCGTGGGCCCCCAGCCAAGGCC GAGGCGTCCCCGGAGCCAGGCCCCGGCCCCGCCGCCCCTGGCCTGCCCAAGGCCCGCAGC TCTGAGGAGCTGGCCCCGCCGCGGCCGCCCGGGCCCTGCTCCTTCCAGCACTTTCGCCGC AGCCTCCGCCACATCTTCCGCCGCCGCTCGGCCGGGGAGCTGCCAGCGGCCCACACCGCT GCCGCCCCCGGGACCCCCGGAGAGGCTGCTGAGACCCCCGCCCGGCCTGGCCTGGCCAAG AAGTTCCTGCCCTGGAGCCTGGCCCGGGAGCCGCCACCCGAGGCGCTGAAGGAGGCGGTG CTGCGCTACAGCCTGGCCGACGAGGCCTCCATGGACAGCGGGGCACGCTGGCAGCGCGGG AGGCTGGCGCTGCGCCGGGCCCCGGGCCCCGATGGCCCCGACCGCGTGCTGGAGCTCTTC GACCCACCCAAGAGTTCAAGGCCCAAGCTACAAGCAGCTTGCTCCAGCATCCAGGAGGTC CGGCGGTGCACACGGCTTGAGATGCCTGACAACCTTTACACCTTTGTGCTGAAGGTGAAG GACCGGACAGACATCATCTTTGAGGTGGGAGACGAGCAGCAGCTGAATTCATGGATGGCT GAGCTCTCGGAGTGCACAGGCCGAGGGCTGGAGAGCACAGAAGCAGAGATGCATATTCCC TCAGCCCTAGAGCCTAGCACGTCCAGCTCCCCAAGGGGCAGCACAGATTCCCTTAACCAA GGTGCTTCTCCTGGGGGGCTGCTGGACCCGGCCTGCCAGAAGACGGACCATTTCCTGTCC TGCTACCCCTGGTTCCACGGCCCCATCTCCAGAGTGAAAGCAGCTCAGCTGGTTCAGCTG CAGGGCCCTGATGCTCATGGAGTGTTCCTGGTGCGGCAGAGCGAGACGCGGCGTGGGGAA TACGTGCTCACTTTCAACTTTCAGGGGATAGCCAAGCACCTGCGCCTGTCGCTGACAGAG CGGGGCCAGTGCCGTGTGCAGCACCTCCACTTTCCCTCGGTCGTGGACATGCTCCACCAC TTCCAGCGCTCGCCCATCCCACTCGAGTGCGGCGCCGCCTGTGATGTCCGGCTCTCCAGC TACGTGGTAGTCGTCTCCCAACCACCAGGTTCCTGCAACACGGTCCTCTTCCCTTTCTCC CTTCCTCACTGGGATTCAGAGTCCCTTCCTCACTGGGGTTCAGAGTTGGGCCTTCCCCAC CTTAGTTCTTCTGGCTGTCCCCGGGGGCTCAGCCCAGAGGGTCTCCCAGGGCGATCCTCA CCCCCCGAGCAGATCTTCCACCTGGTGCCTTCGCCCGAAGAACTGGCCAACAGCCTGCAG CACCTGGAGCATGAGCCTGTGAATCGAGCCCGGGACTCGGACTACGAAATGGACTCATCC TCCCGGAGCCACCTGCGGGCCATAGACAATCAGTACACACCTCTCTGA Clone variation with respect to NM_005475.2 784 t=>c >OriGene 5' read for NM_005475 unedited
TTTCGCCGCCCGTTGNCGCATTGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATAAGCA GAGCTCATTTAGGTGACACTATAGAATACAAGCTACTTGTTCTTTTTGCAGCGGCCGCGA ATTCGGCACGAGGCGGGCCACCGCCTCCGCCCGGCTGCCCGCCCGGACTGTCGCGGCCCG CGGTGGCGACGGCGGCCGCTGCAAAGTTTCCCCGGCGGCGGCGGCCCGGGGGCGCATCCT CCCGCAACTGTCAAGCGCTGGCGGCGGAAATGATGAGGCGCTGGCCATTTTCCGAGCCCG GGTTTCCTGCCTGAGCCCCGCTCGAGCGAGCCGCGAGCGAGGAGCCGGCGGGCGGGAGAG GACGCGCCCAGGGCGGGGGCCCGCCCGCCCCCTCGGGATTTCGAGGGCCCGGGGGCGCGC GACGCCATGGGCCGGCCGGGCCCAGAGCTCCTGTCTCTCAGCCCGGCCGCACCACCTGGG TCTCCGCCATGAACGGGCCTGCCCTGCAGCCCTCCTCGCCCTCTTCCGCGCCCTCAGCCT CCCCGGCGGCGGCCCCGCGGGGCTGGAGCGAGTTCTGTGAGTTGCACGCCGTANCGGCGG CCCGGGAGCTGGCCCGCCAGTACTGGCTGTTCGCCCGGGAGCATNCGCAGCACGCGCCGC TGCGCGCCGAGCTGGTGTCGCTGCAGNTCACCGACCTCTTNCAGCGCTACTTCTGCCCGC GAGGTGCGCGACGGACGGGCGCCGGGCCGCGACTACCGGAACAGGGGCCGTGGGCCCCCA GCCAGCNCCGAGCGTCCCCGGAGCCAAGCCCCGGCCCGCGCCCTGTCTTGCCAGGCGATN TTTTGGANNATTGNCCCCCCCGGGCCCCCGGCCCTGGTCCTCCACATTTGGCGCAACTCG GCATTTCGCCGCTGNGGGGGGGGGGAATGTCCGCGGCCCACCGTGCG >OriGene 3' read for NM_005475 unedited
CGGTAATACTATGNNACCGCGGCCGCATTCTAGNGATCAGTTTTTTTTTTTTTTTTTTGA AAACTTTTTAATTCAATATAGCAATTTGTACATTATAGCAAAATTTGCATTATTCAAGAA TAAGTTACTTGTACAGTACATAAAACAATACATAAAAATTTGCCAAATACCTTCTGCCTA TAATGATACAAGATGAATCCACTTTATGTTATCACAATGTGCTGTATATTCTAACCAAAC ACAGGATGTCAGATGTGTCCTTGTTAATATACTCGCAAGTTCCTCTAGCTTGTGGGAGAT GTTAGAGCTAACACATTTGCAGTAAGGGACTTAGTCCTGAATAGAAAGCATGAAGGAATC TCAGGCAACCCTCAGGGAAGAGTCCAAGGCCTTGACTTTAGGTTAAGAAACTGTTATGTA AAAATAGTGTTCTCTGGCCCAAGATTTTAATGATTGCTATTCCTTTTTCCTACGGTCCAG AAATGATCAAAGGCAGAAGATTTATACCAGATAAAGCCATATGGATTGCTGGTCTAAAAT TCAAGGCAGGTTAGTTGACTTAATTCTTTGGTGCTGGTGACTGTTAGTTTGTAAAAGTTC AATAAGTCAAATGAANGAAGGGATGGTGCCGGGAGCTGTCAAGCTGTACTGGTGGGGTCT GTAATTAGAGCTAACTGGAGGGATCATGATGTCTACTGTCCAGTTTGGTGTTGAGCCATG GCTCTCGGTAAAATTGCCCGCTGGGGCCCGTTCACGACTGGAAAGAAAATGGTGGGAGTG CTTTGCCCTTGGGGGGCAAACTGCACCCATGGGGTGCCTGGCCCCACTGGTGCCCACCCC TTCTAAACTGAAATTGTTCCCCATTAAGAAAAGGGTGGGCTAAGGGCACTTTTTCCTAAA CCATGGGG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_005475 |
| Insert Size | 4700 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_005475.1, NP_005466.1 |
| RefSeq Size | 5423 bp |
| RefSeq ORF | 1728 bp |
| Locus ID | 10019 |
| UniProt ID | Q9UQQ2 |
| Domains | SH2, PH |
| Protein Pathways | Neurotrophin signaling pathway |
| Gene Summary | This gene encodes a member of the SH2B adaptor family of proteins, which are involved in a range of signaling activities by growth factor and cytokine receptors. The encoded protein is a key negative regulator of cytokine signaling and plays a critical role in hematopoiesis. Mutations in this gene have been associated with susceptibility to celiac disease type 13 and susceptibility to insulin-dependent diabetes mellitus. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2014] Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC218359 | SH2B3 (Myc-DDK-tagged)-Human SH2B adaptor protein 3 (SH2B3) |
CNY 4,280.00 |
|
| RC218359L1 | Lenti ORF clone of Human SH2B adaptor protein 3 (SH2B3), Myc-DDK-tagged |
CNY 6,680.00 |
|
| RC218359L2 | Lenti ORF clone of Human SH2B adaptor protein 3 (SH2B3), mGFP tagged |
CNY 6,460.00 |
|
| RC218359L3 | Lenti ORF clone of Human SH2B adaptor protein 3 (SH2B3), Myc-DDK-tagged |
CNY 6,680.00 |
|
| RC218359L4 | Lenti ORF clone of Human SH2B adaptor protein 3 (SH2B3), mGFP tagged |
CNY 6,680.00 |
|
| RG218359 | SH2B3 (tGFP-tagged) - Human SH2B adaptor protein 3 (SH2B3) |
CNY 5,880.00 |
