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LIMPII (SCARB2) (NM_005506) Human Untagged Clone
CAT＃: SC116693
SCARB2 (untagged)-Human scavenger receptor class B, member 2 (SCARB2), transcript variant 1
CNY 3,656.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | AMRF; CD36L2; EPM4; HLGP85; LGP85; LIMP-2; LIMPII; SR-BII |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_005506 edited
CGGCCCGTGAGCGGCGCACAGAATGGGCCGATGCTGCTTCTACACGGCGGGGACGTTGTC CCTGCTCCTGCTGGTGACCAGCGTCACGCTGCTGGTGGCCCGGGTCTTCCAGAAGGCTGT AGACCAGAGTATCGAGAAGAAAATTGTGTTAAGGAATGGTACTGAGGCATTTGACTCCTG GGAGAAGCCCCCTCTGCCTGTGTATACTCAGTTCTATTTCTTCAATGTCACCAATCCAGA GGAGATCCTCAGAGGGGAGACCCCTCGGGTGGAAGAAGTGGGGCCATACACCTACAGGGA ACTCAGAAACAAAGCAAATATTCAATTTGGAGATAATGGAACAACAATATCTGCTGTTAG CAACAAGGCCTATGTTTTTGAACGAGACCAATCTGTTGGAGACCCTAAAATTGACTTAAT TAGAACATTAAATATTCCTGTATTGACTGTCATAGAGTGGTCCCAGGTGCACTTCCTCAG GGAGATCATCGAGGCCATGTTGAAAGCCTATCAGCAGAAGCTCTTTGTGACTCACACAGT TGACGAATTGCTCTGGGGCTACAAAGATGAAATCTTGTCCCTTATCCATGTTTTCAGGCC CGATATCTCTCCCTATTTTGGCCTATTCTATGAGAAAAATGGGACTAATGATGGAGACTA TGTTTTTCTAACTGGAGAAGACAGTTACCTTAACTTTACAAAAATTGTGGAATGGAATGG GAAAACGTCACTTGACTGGTGGATAACAGACAAGTGCAATATGATTAATGGAACAGATGG AGATTCTTTTCACCCACTAATAACCAAAGATGAGGTCCTTTATGTCTTCCCATCTGACTT TTGCAGGTCAGTGTATATTACTTTCAGTGACTATGAGAGTGTACAGGGACTGCCTGCCTT TCGGTATAAAGTTCCTGCAGAAATATTAGCCAATACGTCAGACAATGCCGGCTTCTGTAT ACCTGAGGGAAACTGCCTGGGCTCAGGAGTTCTGAATGTCAGCATCTGCAAGAATGGTGC ACCCATCATTATGTCTTTCCCACACTTTTACCAAGCAGATGAGAGGTTTGTTTCTGCCAT AGAAGGCATGCACCCAAATCAGGAAGACCATGAGACATTTGTGGACATTAATCCTTTGAC TGGAATAATCCTAAAAGCAGCCAAGAGGTTCCAAATCAACATTTATGTCAAAAAATTAGA TGACTTTGTTGAAACGGGAGACATTAGAACCATGGTTTTCCCAGTGATGTACCTCAATGA GAGTGTTCACATTGATAAAGAGACGGCGAGTCGACTGAAGTCTATGATTAACACTACTTT GATCATCACCAACATACCCTACATCATCATGGCGCTGGGTGTGTTCTTTGGTTTGGTTTT TACCTGGCTTGCATGCAAAGGACAGGGATCCATGGATGAGGGAACAGCGGATGAAAGAGC ACCCCTCATTCGAACCTAAACATTGCCTTTGCTTGGTGAAGAAACTGTGTGAGCTGTCCT GACCTGGACGATGACGTGGGGAAACCCTCCACCTCCTTGCAGGCTTGTTGCCTGTTGAAA GAAGGAAAAAGACACGGCGCTGGCAAGTGATAGGAACATTCTGGCCAGAGGTTAAAGAGC AGGCTGACATGGCTGGCCATTAAGCTTTATAAAATCATGTGGGCTCTGAAATTGTTCTTT TATGTGTCTAGCAAGTATTTAATAAACCCTTGTATAGTAAAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_005506 |
| Insert Size | 1700 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | The ORF of this clone has been fully sequenced and found to be a perfect match to NM_005506.2. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_005506.2, NP_005497.1 |
| RefSeq Size | 4748 bp |
| RefSeq ORF | 1437 bp |
| Locus ID | 950 |
| UniProt ID | Q14108 |
| Domains | CD36 |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Lysosome |
| Gene Summary | The protein encoded by this gene is a type III glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes. Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. The protein deficiency in mice was reported to impair cell membrane transport processes and cause pelvic junction obstruction, deafness, and peripheral neuropathy. Further studies in human showed that this protein is a ubiquitously expressed protein and that it is involved in the pathogenesis of HFMD (hand, foot, and mouth disease) caused by enterovirus-71 and possibly by coxsackievirus A16. Mutations in this gene caused an autosomal recessive progressive myoclonic epilepsy-4 (EPM4), also known as action myoclonus-renal failure syndrome (AMRF). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2011] Transcript Variant: This variant (1) encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
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A new animal model containing human SCARB2 and lacking stat-1 is highly susceptible to EV71
,Liou, AT;Wu, SY;Liao, CC;Chang, YS;Chang, CS;Shih, C;,
Sci Rep
,PubMed ID 27499235
[SCARB2]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC202162 | SCARB2 (Myc-DDK-tagged)-Human scavenger receptor class B, member 2 (SCARB2), transcript variant 1 |
CNY 3,656.00 |
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| RC202162L1 | Lenti ORF clone of Human scavenger receptor class B, member 2 (SCARB2), transcript variant 1, Myc-DDK-tagged |
CNY 6,056.00 |
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| RC202162L2 | Lenti ORF clone of Human scavenger receptor class B, member 2 (SCARB2), transcript variant 1, mGFP tagged |
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| RC202162L3 | Lenti ORF clone of Human scavenger receptor class B, member 2 (SCARB2), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
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| RC202162L4 | Lenti ORF clone of Human scavenger receptor class B, member 2 (SCARB2), transcript variant 1, mGFP tagged |
CNY 6,056.00 |
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| RG202162 | SCARB2 (tGFP-tagged) - Human scavenger receptor class B, member 2 (SCARB2), transcript variant 1 |
CNY 5,256.00 |
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| SC322407 | SCARB2 (untagged)-Human scavenger receptor class B, member 2 (SCARB2), transcript variant 1 |
CNY 3,656.00 |
