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IRF6 (NM_006147) Human Untagged Clone
CAT＃: SC116274
IRF6 (untagged)-Human interferon regulatory factor 6 (IRF6), transcript variant 1
CNY 5,488.00
| Cited in 1 publication. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | LPS; OFC6; PIT; PPS; PPS1; VWS; VWS1 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC116274 sequence for NM_006147 edited (data generated by NextGen Sequencing)
ATGGCCCTCCACCCCCGCAGAGTCCGGCTAAAGCCCTGGCTGGTGGCCCAGGTGGATAGT GGCCTCTACCCTGGGCTCATCTGGCTACACAGGGACTCTAAACGCTTCCAGATTCCCTGG AAACATGCCACCCGGCATAGCCCTCAACAAGAAGAGGAAAATACCATTTTTAAGGCCTGG GCTGTAGAGACAGGGAAGTACCAGGAAGGGGTGGATGACCCTGACCCAGCTAAATGGAAG GCCCAGCTGCGCTGTGCTCTCAATAAGAGCAGAGAATTCAACCTGATGTATGATGGCACC AAGGAGGTGCCCATGAACCCAGTGAAGATATATCAAGTGTGTGACATCCCTCAGCCCCAG GGCTCGATCATTAACCCAGGATCCACAGGGTCTGCTCCCTGGGATGAGAAGGATAATGAT GTGGATGAAGAAGATGAGGAAGATGAGCTGGATCAGTCGCAGCACCATGTTCCCATCCAG GACACCTTCCCCTTCCTGAACATCAATGGTTCTCCCATGGCGCCAGCCAGTGTGGGCAAT TGCAGTGTGGGCAACTGCAGCCCGGAGGCAGTGTGGCCCAAAACTGAACCCCTGGAGATG GAAGTACCCCAGGCACCTATACAGCCCTTCTATAGCTCTCCAGAACTGTGGATCAGCTCT CTCCCAATGACTGACCTGGACATCAAGTTTCAGTACCGTGGGAAGGAGTACGGGCAGACC ATGACCGTGAGCAACCCTCAGGGCTGCCGACTCTTCTATGGGGACCTGGGTCCCATGCCT GACCAGGAGGAGCTCTTTGGTCCCGTCAGCCTGGAGCAGGTCAAATTCCCAGGTCCTGAG CATATTACCAATGAGAAGCAGAAGCTGTTCACTAGCAAGCTGCTGGACGTCATGGACAGA GGACTGATCCTGGAGGTCAGCGGTCATGCCATTTATGCCATCAGGCTGTGCCAGTGCAAG GTGTACTGGTCTGGGCCATGTGCCCCATCACTTGTTGCTCCCAACCTGATTGAGAGACAA AAGAAGGTCAAGCTATTTTGTCTGGAAACATTCCTTAGCGATCTCATTGCCCACCAGAAA GGACAGATAGAGAAGCAGCCACCGTTTGAGATCTACTTATGCTTTGGGGAAGAATGGCCA GATGGGAAACCATTGGAAAGGAAACTCATCTTGGTTCAGGTCATTCCAGTAGTGGCTCGG ATGATCTACGAGATGTTTTCTGGTGATTTCACACGATCCTTTGATAGTGGCAGTGTCCGC CTGCAGATCTCAACCCCAGACATCAAGGATAACATCGTTGCTCAGCTGAAGCAGCTGTAC CGCATCCTTCAAACCCAGGAGAGCTGGCAGCCCATGCAGCCCACCCCCAGCATGCAACTG CCCCCTGCCCTGCCTCCCCAGTAA Clone variation with respect to NM_006147.3 >OriGene 5' read for NM_006147 unedited
TTCCCGCCCCGTTGCCGCAAAGGGCGGTAGGCGTGTACGGTGGGAAGGTCTATATAAGCA GAGCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGCGAA TTCGGCACCAGGCGCACCTGGGCTGGGCAGGTAAGGGCTGGTGCGGGACGGGGAGAGGAA CCTGCAGTCCCTACTTGGGTAGAGCCAGGCGCCCCTTGGCTAAGACGTCGAGGAGCGTGG TAGCGACGGGTGATCTTCGCTGCGGACTTGGTTCGGAGGGACGTCCGCTTCTGGTGGACA GATTGAGCAAAGAATCTTTGAGCGGTCAAGGGAAAGACAAGCCGACTCTTCAGATCCCTG TGGACACACTGCCTGCTCTTCCATATCATGGCCCTCCACCCCCGCAGAGTCCGGCTAAAG CCCTGGCTGGTGGCCCAGGTGGATAGTGGCCTCTACCCTGGGCTCATCTGGCTACACAGG GACTCTAAACGCTTCCAGATTCCCTGGAAACATGCCACCCGGCATAGCCCTCAACAAGAA GAGGAAAATACCATTTTTAAGGCCTGGGCTGTAGAGACAGGGAAGTACCAGGAAGGGGTG GATGACCCTGACCCAGCTAAATGGAATGCCCAGCTGCGCTGTGCTCTCAATAAGAGCAGA GAATTCAACCTGATGTATGATGGCACCAATGATGTGCCCATGAACCCAGTGAAGATATAT CAAGTGTGTGACATCCCTCAGCCCCAGGGCTCGATCATTAACCCANGATCCACAGGNTCT GCTCCNTGGGATGAGAAAGGATATGATGTGGATGAAGAATNATGAGGAGATGAGCTGGAT CAGTCGCAGCACCATGGTTCCATTCCAGACACCTNCCCTTNNCTGACAATCATGGNNTCT CCATGGCGCCAGCCANTGTGGGCAATTGCAGTGTGGGCAACTGCAGCCCCGNAGCAT >OriGene 3' read for NM_006147 unedited
NNGGGGTTTTGACTTTGGACCGGCGGCCGCATNCTANGATCGAGTTTTTTTTTTTTTTTT TTCCTAAATTAAATCAGCTTTAAATCTAGGCATATTTGGGAAAATCACAAACTTCTAACA CTGTTAGAGAAAAGAGAGATTTAAAAGCTGGTTAAATCTAAACAATAAAAAAATCCATAT GTACAATATTATAAAAAAGAGAAGGAAGAAGATGGCATTCACAATTACTGGGGAGGCAGG GCAGGGGGCAGTTGCATGCTGGGGGTGGGCTGCATGGGCTGCCAGCTCTCCTGGGTTTGA AGGATGCGGTACAGCTGCTTCAGCTGAGCAACGATGTTATCCTTGATGTCTGGGGTTGAG ATCTGCAGGCGGACACTGCCACTATCAAAGGATCGTGTGAAATCACCAGAAAACATCTCG TAGATCATCCGAGCCACTACTGGAATGACCTGAACCAAGATGAGTTTCCTTTCCAATGGT TTCCCATCTGGCCATTCTTCCCCAAAGCATAAGTAGATCTCAAACGGTGGCTGCTTCTCT ATCTGTCCTTTCTGGTGGGCAATGAGATCGCTAAGGAATGTTTCCAGACAAAATAGCTTG ACCTTCTTTTGTCTCTCAATCAGGTTGGGAGCAACAAGTGATGGGGCACATGGCCCAGAC CAGTACACCTTGCACTGGCACAGCCTGATGGCATAAATGGCATGACCGCTGACCTCCAGG ATCAGTCCTCTGTCCATGACGTCCAGCAGCTTGCTAGTGAACAGCTTCTGCTTCTCATTG GTAATATGCTCAGGACCTGGGAATTTGACCTGCTCCAGGCTGACGGGGACCAAAGAGCTC TCCTGGTCAGGCATGGGACCCCAGTCCNCATAGAAAGAGTCGCAGCCCTGGAGGGTGCTC ACGTNCATGGTCTGCCCGTACTCTTCN |
| Restriction Sites | NotI-NotI |
| ACCN | NM_006147 |
| Insert Size | 2100 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_006147.2, NP_006138.1 |
| RefSeq Size | 2171 bp |
| RefSeq ORF | 1404 bp |
| Locus ID | 3664 |
| UniProt ID | O14896 |
| Domains | IRF |
| Protein Families | ES Cell Differentiation/IPS, Transcription Factors |
| Gene Summary | This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. The encoded protein may be a transcriptional activator. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. Mutations in this gene are also associated with non-syndromic orofacial cleft type 6. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2011] Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Interferon Regulatory Factor 6 differentially regulates Toll-like Receptor 2-dependent chemokine gene expression in epithelial cells
,Kwa, MQ;Nguyen, T;Huynh, J;Ramnath, D;De Nardo, D;Lam, PY;Reynolds, EC;Hamilton, JA;Sweet, MJ;Scholz, GM;,
J. Biol. Chem.
,PubMed ID 24872416
[IRF6]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC201579 | IRF6 (Myc-DDK-tagged)-Human interferon regulatory factor 6 (IRF6), transcript variant 1 |
CNY 5,488.00 |
|
| RC201579L1 | Lenti ORF clone of Human interferon regulatory factor 6 (IRF6), transcript variant 1, Myc-DDK-tagged |
CNY 7,888.00 |
|
| RC201579L2 | Lenti ORF clone of Human interferon regulatory factor 6 (IRF6), transcript variant 1, mGFP tagged |
CNY 7,888.00 |
|
| RC201579L3 | Lenti ORF clone of Human interferon regulatory factor 6 (IRF6), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC201579L4 | Lenti ORF clone of Human interferon regulatory factor 6 (IRF6), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RG201579 | IRF6 (tGFP-tagged) - Human interferon regulatory factor 6 (IRF6), transcript variant 1 |
CNY 7,088.00 |
|
| SC322491 | IRF6 (untagged)-Human interferon regulatory factor 6 (IRF6), transcript variant 1 |
CNY 5,488.00 |
