NC2 alpha (DRAP1) (NM_006442) Human Untagged Clone
CAT#: SC116124
DRAP1 (untagged)-Human DR1-associated protein 1 (negative cofactor 2 alpha) (DRAP1)
CNY 2,400.00
CNY 2,950.00
Product images
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Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | NC2-alpha |
Vector | pCMV6-XL5 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>NCBI ORF sequence for NM_006442, the custom clone sequence may differ by one or more nucleotides
ATGCCGAGCAAGAAGAAGAAGTACAACGCGCGGTTCCCGCCGGCGCGGATCAAGAAGATCATGCAGACGG ACGAAGAGATTGGGAAGGTGGCGGCGGCGGTGCCTGTCATCATCTCCCGGGCGCTCGAGCTCTTCCTAGA GTCGCTGTTGAAGAAGGCCTGCCAGGTGACCCAGTCGCGGAACGCGAAGACCATGACCACATCCCACCTG AAGCAGTGCATCGAGCTGGAGCAGCAGTTTGACTTCTTGAAGGACCTGGTGGCATCTGTTCCCGACATGC AGGGGGACGGGGAAGACAACCACATGGATGGGGACAAGGGCGCCCGCAGGGGCCGGAAGCCAGGCAGCGG CGGCCGGAAGAACGGTGGGATGGGAACGAAAAGCAAGGACAAGAAGCTGTCCGGGACAGACTCGGAGCAG GAGGATGAATCTGAGGACACAGATACTGATGGGGAAGAGGAGACATCACAACCCCCACCCCAGGCCAGCC ACCCCTCTGCCCACTTTCAGAGCCCCCCGACACCCTTCCTGCCCTTCGCCTCTACTCTGCCTTTGCCCCC AGCGCCCCCGGGCCCCTCAGCACCTGATGAAGAGGACGAAGAAGATTACGACTCCTAG >OriGene 5' read for NM_006442 unedited
CACGAGGGGAGCCGGGAGGCTGCGGGCGGCGGCGCTGGACCCGACGCGGCGAGAGAGGCC CCGAGATGCCGAGCAAGAAGAAGAAGTACAACGCGCGGTTCCCGCCGGCGCGGATCAAGA AGATCATGCAGACGGACGAAGAGATTGGGAAGGTGGCGGCGGCGGTGCCTGTCATCATCT CCCGGGCGCTCGAGCTCTTCCTAGAGTCGCTGTTGAAGAAGGCCTGCCAGGTGACCCAGT CGCGGAACGCGAAGACCATGACCACATCCCACCTGAAGCAGTGCATCGAGCTGGAGCAGC AGTTTGACTTCTTGAAGGACCTGGTGGCATCTGTTCCCGACATGCAGGGGGACGGGGAAG ACAACCACATGGATGGGGACAAGGGCGCCCGCAGGGGCCGGAAGCCAGGCAGCGGCGGCC GGAAGAACGGTGGGATGGGAACGAAAAGCAAGGACAAGAAGCTGTCCGGGACAGACTCGG AGCAGGAGGATGAATCTGAGGACACAGATACTGATGGGGAAGAGGAACATNNACAAACCC CCACCCCAGGCCAGCCACCCCTCTGCCCACTTTCAGAGCCCCCCGACACCCTTCCTGCCC TTCGCCTCTACTCTGCCTTTGCCCCCAGCGCCCCCGGGCCCCTCAGCACCTGATGAAGAG GACGAAGAAGATTACGACTCCTAGCGCCTTCTGCCCCCCAGACCATAGCCCCTTTTAGTT GGTT |
Restriction Sites | NotI-NotI |
ACCN | NM_006442 |
Insert Size | 890 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_006442.2, NP_006433.2 |
RefSeq Size | 988 bp |
RefSeq ORF | 618 bp |
Locus ID | 10589 |
UniProt ID | Q14919 |
Protein Families | Transcription Factors |
Gene Summary | Transcriptional repression is a general mechanism for regulating transcriptional initiation in organisms ranging from yeast to humans. Accurate initiation of transcription from eukaryotic protein-encoding genes requires the assembly of a large multiprotein complex consisting of RNA polymerase II and general transcription factors such as TFIIA, TFIIB, and TFIID. DR1 is a repressor that interacts with the TATA-binding protein (TBP) of TFIID and prevents the formation of an active transcription complex by precluding the entry of TFIIA and/or TFIIB into the preinitiation complex. The protein encoded by this gene is a corepressor of transcription that interacts with DR1 to enhance DR1-mediated repression. The interaction between this corepressor and DR1 is required for corepressor function and appears to stabilize the TBP-DR1-DNA complex. [provided by RefSeq, Jul 2008] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC204031 | DRAP1 (Myc-DDK-tagged)-Human DR1-associated protein 1 (negative cofactor 2 alpha) (DRAP1) |
CNY 2,400.00 |
|
RC204031L1 | Lenti ORF clone of Human DR1-associated protein 1 (negative cofactor 2 alpha) (DRAP1), Myc-DDK-tagged |
CNY 4,800.00 |
|
RC204031L2 | Lenti ORF clone of Human DR1-associated protein 1 (negative cofactor 2 alpha) (DRAP1), mGFP tagged |
CNY 5,890.00 |
|
RC204031L3 | Lenti ORF clone of Human DR1-associated protein 1 (negative cofactor 2 alpha) (DRAP1), Myc-DDK-tagged |
CNY 5,890.00 |
|
RC204031L4 | Lenti ORF clone of Human DR1-associated protein 1 (negative cofactor 2 alpha) (DRAP1), mGFP tagged |
CNY 5,890.00 |
|
RG204031 | DRAP1 (tGFP-tagged) - Human DR1-associated protein 1 (negative cofactor 2 alpha) (DRAP1) |
CNY 4,000.00 |
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