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Hsp105 (HSPH1) (NM_006644) Human Untagged Clone
CAT＃: SC115932
HSPH1 (untagged)-Human heat shock 105kDa/110kDa protein 1 (HSPH1)
CNY 6,288.00
| Cited in 2 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | HSP105; HSP105A; HSP105B; NY-CO-25 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC115932 sequence for NM_006644 edited (data generated by NextGen Sequencing)
ATGTCGGTGGTGGGGTTGGACGTGGGCTCGCAGAGCTGCTACATCGCGGTAGCCCGGGCC GGGGGCATCGAGACCATCGCCAATGAGTTCAGCGACCGGTGCACCCCGTCAGTCATATCA TTTGGATCAAAAAATAGAACAATCGGAGTTGCAGCCAAAAATCAGCAAATCACTCATGCA AACAATACGGTGTCTAACTTCAAAAGATTTCATGGCCGAGCATTCAACGACCCCTTCATT CAAAAGGAGAAGGAAAACTTGAGTTACGATTTGGTTCCATTGAAAAATGGTGGAGTTGGA ATAAAGGTAATGTACATGGGTGAAGAACATCTATTTAGTGTGGAGCAGATAACAGCCATG TTGTTGACTAAGCTGAAGGAAACTGCTGAAAACAGCCTCAAGAAACCAGTAACAGATTGT GTTATTTCAGTCCCCTCCTTCTTTACAGATGCTGAGAGGCGATCTGTGTTAGATGCTGCA CAGATTGTTGGCCTAAACTGTTTAAGACTTATGAATGACATGACAGCTGTTGCTTTGAAT TACGGAATTTATAAGCAGGATCTCCCAAGCCTGGATGAGAAACCTCGGATAGTGGTTTTT GTTGATATGGGACATTCAGCTTTTCAAGTGTCTGCTTGTGCTTTTAACAAGGGAAAATTG AAGGTACTGGGAACAGCTTTTGATCCTTTCTTAGGAGGAAAAAACTTCGATGAAAAGTTA GTGGAACATTTCTGTGCAGAATTTAAAACTAAGTACAAGTTGGATGCAAAATCCAAAATA CGAGCACTCCTACGTCTGTATCAGGAATGTGAAAAACTGAAAAAGCTAATGAGCTCTAAC AGCACAGACCTTCCACTGAATATCGAATGCTTTATGAATGATAAAGATGTTTCCGGAAAG ATGAACAGGTCACAATTTGAAGAACTCTGTGCTGAACTTCTGCAAAAGATAGAAGTACCC CTTTATTCACTGTTGGAACAAACTCATCTCAAAGTAGAAGATGTGAGTGCAGTTGAGATT GTTGGAGGCGCTACACGAATTCCAGCTGTGAAGGAAAGAATTGCCAAATTCTTTGGAAAA GATATTAGCACAACACTCAATGCAGATGAAGCAGTAGCCAGAGGATGTGCATTACAGTGT GCAATACTTTCCCCGGCATTTAAAGTTAGAGAATTTTCCGTCACAGATGCAGTTCCTTTT CCAATATCTCTGATCTGGAACCATGATTCAGAAGATACTGAAGGTGTTCATGAAGTCTTT AGTCGAAACCATGCTGCTCCTTTCTCCAAAGTTCTCACCTTTCTGAGAAGGGGGCCTTTT GAGCTAGAAGCTTTCTATTCTGATCCCCAAGGAGTTCCATATCCAGAAGCAAAAATAGGC CGCTTTGTAGTTCAGAATGTTTCTGCACAGAAAGATGGAGAAAAATCTAGAGTAAAAGTC AAAGTGCGAGTCAACACCCATGGCATTTTCACCATCTCTACGGCATCTATGGTGGAGAAA GTCCCAACTGAGGAGAATGAAATGTCTTCTGAAGCTGACATGGAGTGTCTGAATCAGAGA CCACCAGAAAACCCAGACACTGATAAAAATGTCCAGCAAGACAACAGTGAAGCTGGAACA CAGCCCCAGGTACAAACTGATGCTCAACAAACCTCACAGTCTCCCCCTTCACCTGAACTT ACCTCAGAAGAAAACAAAATCCCAGATGCTGACAAAGCAAATGAAAAAAAAGTTGACCAG CCTCCAGAAGCTAAAAAGCCCAAAATAAAGGTGGTGAATGTTGAGCTGCCTATTGAAGCC AACTTGGTCTGGCAGTTAGGGAAAGACCTTCTTAACATGTATATTGAGACAGAGGGTAAG ATGATAATGCAAGATAAATTGGAAAAAGAAAGGAATGATGCTAAAAATGCAGTTGAGGAA TATGTGTATGAGTTCAGAGACAAGCTGTGTGGACCATATGAAAAATTTATATGTGAGCAG GATCATCAAAATTTTTTGAGACTCCTCACAGAAACTGAAGACTGGCTGTATGAAGAAGGA GAGGACCAAGCTAAACAAGCATATGTTGACAAGTTGGAAGAATTAATGAAAATTGGCACT CCAGTTAAAGTTCGGTTTCAGGAAGCTGAAGAACGGCCAAAAATGTTTGAAGAACTAGGA CAGAGGCTGCAGCATTATGCCAAGATAGCAGCTGACTTCAGAAATAAGGATGAGAAATAC AACCATATTGATGAGTCTGAAATGAAAAAAGTGGAGAAGTCTGTTAATGAAGTGATGGAA TGGATGAATAATGTCATGAATGCTCAGGCTAAAAAGAGTCTTGATCAGGATCCAGTTGTA CGTGCTCAGGAAATTAAAACAAAAATCAAGGAATTGAACAACACATGTGAACCCGTTGTA ACACAACCGAAACCAAAAATTGAATCACCCAAACTGGAAAGAACTCCAAATGGCCCAAAT ATTGATAAAAAGGAAGAAGATTTAGAAGACAAAAACAATTTTGGTGCTGAACCTCCACAT CAGAATGGTGAATGTTACCCTAATGAGAAAAATTCTGTTAATATGGACTTGGACTAG Clone variation with respect to NM_006644.2 228 t=>c;732 t=>c >OriGene 5' read for NM_006644 unedited
ATACGACTACTATAGGGCGGCCGCGAATCGGCACGAGGGGCTGAGGAAGTGGGACCTCCC CTTTTGGGTCGGTAGTTCAGCGCCGGCGCCGGTGTGCGAGCCGCGGCAGAGTGAGGCAGG CAACCCGAGGTGCGGAGCGACCTGCGGAGGCTGAGCCCCGCTTTCTCCCAGGGTTTCTTA TCAGCCAGCCGCCGCTGTCCCCGGGGGAGTAGGAGGCTCCTGACAGGCCGCGGCTGTCTG TGTGTCCTTCTGAGTGTCAGAGGAACGGCCAGACCCCGCGGGCCGGAGCAGAACGCGGCC AGGGCAGAAAGCGGCGGCAGGAGAAGCAGGCAGGGGGCCGGAGGACGCAGACCGAGACCC GAGGCGGAGGCGGACCGCGAGCCGGCCATGTCGGTGGTGGGGTTGGACGTGGGCTCGCAG AGCTGCTACATCGCGGTAGCCCGGGCCGGGGGCATCGAGACCATCGCCAATGAGTTCAGC GACCGGTGCACCCCGTCAGTCATATCATTTGGATCAAAAAATAGAACAATCGGAGTTGCA GCCAAAAATCAGCAAATCACTCATGCAAACAATACGGTGTCTAACTTCAAAAGATTTCAT GGCCGAGCATTCAACGACCCCTTCATTCAAAAGGAGAAGGAAAACTTGAGTTACGATTTG GTTCCATTGAAAAATGGTGGAGTTGGAATAAGGTAATGTACATGGGTGAAGACATCTATN TAGTGTGGAGCAGATACAGCCATGTTGNTGACTAAGCTGAAGGAAACTGCTGAAAACAGC CTCAAGAACCAGTNNACAGATGTGTATTTCAGTCCCCTCCTTCTTTACGATGCTGAGAGG CGATCTGTGNTAGATGCTGCACAGATGGNTGCCCTAACTGTNTAGAACTATGAATGACAT GACAGCTGTGCTTTGATTACGGAATTATAANCAGACTCCCAGCCTGATGAGAACTCGGGA AGGGGGGTTTGTGGAATGGAAANTCACCTTNCAGGGTCTGCTGTGCTTACAGGAN >OriGene 3' read for NM_006644 unedited
GCTATGGACCGGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTTGGAAAGAC ACCATAAGATGAACTTTATTTTAAAGCTCATAAAAGTGTTCACAATCAGTTACAACAGGA TCGACATTTCTTCCATTCCACACTTTCACATGACAATATACTGTATAGTGAGAGAGAAAG TTTAAAGTTTTTGTTCTGCATGCTGCTAACACATTTGACTAGCTTTTGTTTTACTCATTG AATTTTTAATATCAAAGCAAAAAGTCATTTTCTCTTGGACAGAAATGGTTTTAGAAAGCC CTTATGAAGTCAGACTTAGTCTTGTTTATAAACATCCACACCCACACACATGCTGAATGG AGAGCAAAATGCAAGAAAACTACCTTGGCAGGAACAAATGCTTAAAGATTTTAATCACAG CCCTCTTGAACAAGCAGTACAGTTTTTTTTCTCCAAAAGACAAAAGTCAGTTTCATCCTC AGTGATGCAAATGGTGAGACTGCACAGAAAGCTTAGTATGAATTCACAATTCCACAGGAA TCTGAAAGTTACCAAGGCAATTTTCCCTTTTAGGATCATAAAGACTACAGACTTAAGCTT TTTTTCTTTTTCCATATAATACACAAAATTTCTAAATATCCTTAAAAAAGAAAATATAAA TAGTTTCAGTATGTTATGTAGAGTCACATACTATGGCAAAAATATTTTATTAATTGAAGG AATAGGCCAATTTAAGGTTATCTAGTCCAAGTCCATATTAACAGAATTTTTCTCATTAGG GTAACATTCACCATTCTGTGGNGGGNAGGTTCAGCACCAAAAATGGNGTTTTGGNCTTCT AAATCTTCTTCCTTTTTATCAATNATTTGGCCAATTTTGGNAGTCTTTTCCAGTTTGGGT GAGTCAAATNTTGGGNTTTCGCGTTGGGGTACAACNGGGNTCACAAGGNGGTGNTCAATT CCCTTGAATTTTGGTTTAATTCCCTGAGCCGTACACCTGGAAA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_006644 |
| Insert Size | 4000 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_006644.2, NP_006635.2 |
| RefSeq Size | 3680 bp |
| RefSeq ORF | 2577 bp |
| Locus ID | 10808 |
| UniProt ID | Q92598 |
| Domains | HSP70 |
| Protein Families | Stem cell - Pluripotency |
| Gene Summary | This gene encodes a member of the heat shock protein 70 family of proteins. The encoded protein functions as a nucleotide exchange factor for the molecular chaperone heat shock cognate 71 kDa protein (Hsc70). In addition, this protein plays a distinct but related role as a holdase that inhibits the aggregation of misfolded proteins, including the cystic fibrosis transmembrane conductance regulator (CFTR) protein. Elevated expression of this protein has been observed in numerous human cancers. [provided by RefSeq, Mar 2017] Transcript Variant: This variant (1) represents the longest transcript and encodes isoform 1, also known as Hsp105alpha. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Mutational Analysis of Sse1 (Hsp110) Suggests an Integral Role for this Chaperone in Yeast Prion Propagation In Vivo
,Ciara Moran, Gemma K. Kinsella, Zai-Rong Zhang, Sarah Perrett, and Gary W. Jones,
g3, Aug 2013; 3: 1409 - 1418.
,PubMed ID 23797105
[HSPH1]
|
|
The chaperone network connected to human ribosome-associated complex (mRAC)
,Himjyot Jaiswal, Charlotte Conz, Hendrik Otto, Tina Wölfle, Edith Fitzke, Matthias P. Mayer, and Sabine Rospert,
Mol. Cell. Biol., Jan 2011; 10.1128/MCB.00986-10
[HSPH1]
|
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC207102 | HSPH1 (Myc-DDK-tagged)-Human heat shock 105kDa/110kDa protein 1 (HSPH1) |
CNY 6,288.00 |
|
| RC207102L1 | Lenti ORF clone of Human heat shock 105kDa/110kDa protein 1 (HSPH1), Myc-DDK-tagged |
CNY 8,688.00 |
|
| RC207102L2 | Lenti ORF clone of Human heat shock 105kDa/110kDa protein 1 (HSPH1), mGFP tagged |
CNY 5,890.00 |
|
| RC207102L3 | Lenti ORF clone of Human heat shock 105kDa/110kDa protein 1 (HSPH1), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC207102L4 | Lenti ORF clone of Human heat shock 105kDa/110kDa protein 1 (HSPH1), mGFP tagged |
CNY 5,890.00 |
|
| RG207102 | HSPH1 (tGFP-tagged) - Human heat shock 105kDa/110kDa protein 1 (HSPH1) |
CNY 7,888.00 |
