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Complement Component 6 (C6) (NM_000065) Human Untagged Clone
CAT＃: SC115886
C6 (untagged)-Human complement component 6 (C6), transcript variant 1
CNY 6,848.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC115886 sequence for NM_000065 edited (data generated by NextGen Sequencing)
ATGGCCAGACGCTCTGTCTTGTACTTCATCCTGCTGAATGCTCTGATCAACAAGGGCCAA GCCTGCTTCTGTGATCACTATGCATGGACTCAGTGGACCAGCTGCTCAAAAACTTGCAAT TCTGGAACCCAGAGCAGACACAGACAAATAGTAGTAGATAAGTACTACCAGGAAAACTTT TGTGAACAGATTTGCAGCAAGCAGGAGACTAGAGAATGTAACTGGCAAAGATGCCCCATC AACTGCCTCCTGGGAGATTTTGGACCATGGTCAGACTGTGACCCTTGTATTGAAAAACAG TCTAAAGTTAGATCTGTCTTGCGTCCCAGTCAGTTTGGGGGACAGCCATGCACTGAGCCT CTGGTAGCCTTTCAACCATGCATTCCATCTAAGCTCTGCAAAATTGAAGAGGCTGACTGC AAGAATAAATTTCGCTGTGACAGTGGCCGCTGCATTGCCAGAAAGTTAGAATGCAATGGA GAAAATGACTGTGGAGACAATTCAGATGAAAGGGACTGTGGGAGGACAAAGGCAGTATGC ACACGGAAGTATAATCCCATCCCTAGTGTACAGTTGATGGGCAATGGGTTTCATTTTCTG GCAGGAGAGCCCAGAGGAGAAGTCCTTGATAACTCTTTCACTGGAGGAATATGTAAAACT GTCAAAAGCAGTAGGACAAGTAATCCATACCGTGTTCCGGCCAATCTGGAAAATGTCGGC TTTGAGGTACAAACTGCAGAAGATGACTTGAAAACAGATTTCTACAAGGATTTAACTTCT CTTGGACACAATGAAAATCAACAAGGCTCATTCTCAAGTCAGGGGGGGAGCTCTTTCAGT GTACCAATTTTTTATTCCTCAAAGAGAAGTGAAAATATCAACCATAATTCTGCCTTCAAA CAAGCCATTCAAGCCTCTCACAAAAAGGATTCTAGTTTTATTAGGATCCATAAAGTGATG AAAGTCTTAAACTTCACAACGAAAGCTAAAGATCTGCACCTTTCTGATGTCTTTTTGAAA GCACTTAACCATCTGCCTCTAGAATACAACTCTGCTTTGTACAGCCGAATATTCGATGAC TTTGGGACTCATTACTTCACCTCTGGCTCCCTGGGAGGCGTGTATGACCTTCTCTATCAG TTTAGCAGTGAGGAACTAAAGAACTCAGGTTTAACCGAGGAAGAAGCCAAACACTGTGTC AGGATTGAAACAAAGAAACGCGTTTTATTTGCTAAGAAAACAAAAGTGGAACATAGGTGC ACCACCAACAAGCTGTCAGAGAAACATGAAGGTTCATTTATACAGGGAGCAGAGAAATCC ATATCCCTGATTCGAGGTGGAAGGAGTGAATATGGAGCAGCTTTGGCATGGGAGAAAGGG AGCTCTGGTCTGGAGGAGAAGACATTTTCTGAGTGGTTAGAATCAGTGAAGGAAAATCCT GCTGTGATTGACTTTGAGCTTGCCCCCATCGTGGACTTGGTAAGAAACATCCCCTGTGCA GTGACAAAACGGAACAACCTCAGGAAAGCTTTGCAAGAGTATGCAGCCAAGTTCGATCCT TGCCAGTGTGCTCCATGCCCTAATAATGGCCGACCCACCCTCTCAGGGACTGAATGTCTG TGTGTGTGTCAGAGTGGCACCTATGGTGAGAACTGTGAGAAACAGTCTCCAGATTATAAA TCCAATGCAGTAGACGGACAGTGGGGTTGTTGGTCTTCCTGGAGTACCTGTGATGCTACT TATAAGAGATCGAGAACCCGAGAATGCAATAATCCTGCCCCCCAACGAGGAGGGAAACGC TGTGAGGGGGAGAAGCGACAAGAGGAAGACTGCACATTTTCAATCATGGAAAACAATGGA CAACCATGTATCAATGATGATGAAGAAATGAAAGAGGTCGATCTTCCTGAGATAGAAGCA GATTCCGGGTGTCCTCAGCCAGTTCCTCCAGAAAATGGATTTATCCGGAATGAAAAGCAA CTATACTTGGTTGGAGAAGATGTTGAAATTTCATGCCTTACTGGCTTTGAAACTGTTGGA TACCAGTACTTCAGATGCTTACCAGACGGGACCTGGAGACAAGGGGATGTGGAATGCCAA CGGACGGAGTGCATCAAGCCAGTTGTGCAGGAAGTCCTGACAATTACACCATTTCAGAGA TTGTATAGAATTGGTGAATCCATTGAGCTAACTTGCCCCAAAGGCTTTGTTGTTGCTGGG CCATCAAGGTACACATGCCAGGGGAATTCCTGGACACCACCCATTTCAAACTCTCTCACC TGTGAAAAAGATACTCTAACAAAATTAAAAGGCCATTGTCAGCTGGGACAGAAACAATCA GGATCTGAATGCATTTGTATGTCTCCAGAAGAAGACTGTAGCCATCATTCAGAAGATCTC TGTGTGTTTGACACAGACTCCAACGATTACTTTACTTCACCCGCTTGTAAGTTTTTGGCT GAGAAATGTTTAAATAATCAGCAACTCCATTTTCTACATATTGGTTCCTGCCAAGACGGC CGCCAGTTAGAATGGGGTCTTGAAAGGACAAGACTTTCATCCAACAGCACAAAGAAAGAA TCCTGTGGCTATGACACCTGCTATGACTGGGAAAAATGTTCAGCCTCCACTTCCAAATGT GTCTGCCTATTGCCCCCACAGTGCTTCAAGGGTGGAAACCAACTCTACTGTGTCAAAATG GGATCATCAACAAGTGAGAAAACATTGAACATCTGTGAAGTGGGAACTATAAGATGTGCA AACAGGAAGATGGAAATACTGCATCCTGGAAAGTGTTTGGCCTAG Clone variation with respect to NM_000065.2 356 c=>a >OriGene 5' read for NM_000065 unedited
CTAGATTTTGTATCCGACTTACTATNAGGNCGGCACGCGCAATTCGGCACGAGGCATTGC CTTGTGTTAGCTAGCAATAAGAAAAGAAGCTTTGTTTGGATTAACATATATACCCTCTTC ATTCTGCATACCTATTTTTTCCCCAATAATTTGCAGCTTATGTCCGAGGACACCACAAAC TCTGCTTAAAGGGCCTGGAGGCTCTCAAGGCATGGCCAGACGCTCTGTCTTGTACTTCAT CCTGCTGAATGCTCTGATCAACAAGGGCCAAGCCTGCTTCTGTGATCACTATGCATGGAC TCAGTGGACCAGCTGCTCAAAAACTTGCAATTCTGGAACCCAGAGCAGACACAGACAAAT AGTAGTAGATAAGTACTACCAGGAAAACTTTTGTGAACAGATTTGCAGCAAGCAGGAGAC TAGAGAATGTAACTGGCAAAGATGCCCCATCAACTGCCTCCTGGGAGATTTTGGACCATG GTCAGACTGTGACCCTTGTATTGAAAAACAGTCTAAAGTTAGATCTGTCTTGCGTCCCAG TCAGTTTGGGGGACAGCCATGCACTGAGCCTCTGGTAGCCTTTCAACCATGCATTCCATC TAAGCTCTGCAAAATTGAAGAGGCTGACTGCAAGAATAAATTTCGCTGTGACAGTGGCCG CTGCATTGCCAGATAGTTAGAATGCAATGGAGAAAATGACTGTGGAGACCATTCAGATGA TAGGGACTGTGGGAGGACATAGGCAGTATGCACACGGAAGTATAATCCCATCCCTAGTGT ACAGTTGATGGGCAATGGNGTTCATTTTCTGGCAAGAGAGCCCAGAAGAGAAGTCCTTGA TACTCTTNCCTGGNAGAATATGTAAACTGTCAAAGCAGTAGGACAAGTAATCATACCGTG TNCCGCCATCTGNAAATGTCGCTTNGAGTACAACTGCAGAGAGACTGAA >OriGene 3' read for NM_000065 unedited
TTCTATGNACCGCGCCGCATTCTAGGATCGAGTTTTTTTTTTTTTTTTTTTCAGAGTTCT GGAGATTTCTGTTTATTAACTCATTGAAAAAAATATGGGTTTTATTCTTATTTCTAATTG TGAGAATGCTTAATGTCACAGGCTACATAAGGGCCTCAAAAGTCACATTATTTTTGTACA ATGTGAACAGGAGAATTTACGAGACTGCTGTGGAAGTTGGTACCTAGGGGTATGCTACAG GGCGTCATGAGCTGGAACTGAATAAGACATGCCCAAACAGGAGAGTCAGGGGAGAATAAT GATCTCAAACTAACAGAAAATAATTTTTGTCAGTAACTTTGAGCATGCCAGTCTGCTGTT TGTGCAAGAATTCTCATTTGTAGGAGTTGGTTCTTCGGGATGGTAAATCTGTTCATTGTG CTGGGCCTAGCAGTAATTGTGCTAGGCCAAACACTTTCCAGGATGCAGTATTTCCATCTT CCTGTTTGCACATCTTATAGTTCCCACTTCACAGATGTTCAATGTTTTCTCACTTGTTGA TGATCCCATTTTGACACAGTAGAGTTGGTTTCCACCCTTGAAGCACTGTGGGGGCAATAG GCAGACACATTTGGAAGTGGAGGCTGAACATTNTTCCCAGTCATAGCAGGTGTCATAGCC ACAGGATTCTTTCTTTGTGCTGTTGGATGAAAGTCTTGTCCTTTCAGACCCCATTCTAAC TGGNCGCCGTCTTGGCAGGAACCCATATGTAGAANATGGGAGTGCTGATTATTTAAACAT TNCTCACCAAAAACTTTACAGCGGGTGAAGTAAAGTATCGTTGGAGTCTGTGTCAAACCA CAGAGATCTTCTGATGATGGCTACAGTCTTCTTCTGGAGAATACAAAGCATTCGATCCTG ANTGTTCTGTCCAGCTGACATGGCCTTTTAANTTGTAGATATCTTTTACAGTGAAAA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_000065 |
| Insert Size | 3110 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_000065.1, NP_000056.1 |
| RefSeq Size | 3551 bp |
| RefSeq ORF | 2805 bp |
| Locus ID | 729 |
| UniProt ID | P13671 |
| Domains | CCP, tsp_1, MACPF, ldl_recept_a, kazal, FIMAC |
| Protein Families | Druggable Genome, Secreted Protein |
| Protein Pathways | Complement and coagulation cascades, Prion diseases, Systemic lupus erythematosus |
| Gene Summary | This gene encodes a component of the complement cascade. The encoded protein is part of the membrane attack complex that can be incorporated into the cell membrane and cause cell lysis. Mutations in this gene are associated with complement component-6 deficiency. Transcript variants encoding the same protein have been described.[provided by RefSeq, Nov 2012] Transcript Variant: This variant (1) represents the predominant transcript. Variants 1 and 2 both encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC207784 | C6 (Myc-DDK-tagged)-Human complement component 6 (C6), transcript variant 1 |
CNY 6,840.00 |
|
| RC207784L3 | Lenti ORF clone of Human complement component 6 (C6), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC207784L4 | Lenti ORF clone of Human complement component 6 (C6), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RG207784 | C6 (tGFP-tagged) - Human complement component 6 (C6), transcript variant 1 |
CNY 8,440.00 |
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