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Methionine Aminopeptidase 2 (METAP2) (NM_006838) Human Untagged Clone
CAT＃: SC115832
METAP2 (untagged)-Human methionyl aminopeptidase 2 (METAP2)
CNY 3,656.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | MAP2; MNPEP; p67eIF2 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC115832 sequence for NM_006838 edited (data generated by NextGen Sequencing)
ATGGCGGGTGTGGAGGAGGTAGCGGCCTCCGGGAGCCACCTGAATGGCGACCTGGATCCA GACGACAGGGAAGAAGGAGCTGCCTCTACGGCTGAGGAAGCAGCCAAGAAAAAAAGACGA AAGAAGAAGAAGAGCAAAGGGCCTTCTGCAGCAGGGGAACAGGAACCTGATAAAGAATCA GGAGCCTCAGTGGATGAAGTAGCAAGACAGTTGGAAAGATCAGCATTGGAAGATAAAGAA AGAGATGAAGATGATGAAGATGGAGATGGCGATGGAGATGGAGCAACTGGAAAGAAGAAG AAAAAGAAGAAGAAGAAGAGAGGACCAAAAGTTCAAACAGACCCTCCCTCAGTTCCAATA TGTGACCTGTATCCTAATGGTGTATTTCCCAAAGGACAAGAATGCGAATACCCACCCACA CAAGATGGGCGAACAGCTGCTTGGAGAACTACAAGTGAAGAAAAGAAAGCATTAGATCAG GCAAGTGAAGAGATTTGGAATGATTTTCGAGAAGCTGCAGAAGCACATCGACAAGTTAGA AAATACGTAATGAGCTGGATCAAGCCTGGGATGACAATGATAGAAATCTGTGAAAAGTTG GAAGACTGTTCACGCAAGTTAATAAAAGAGAATGGATTAAATGCAGGCCTGGCATTTCCT ACTGGATGTTCTCTCAATAATTGTGCTGCCCATTATACTCCCAATGCCGGTGACACAACA GTATTACAGTATGATGACATCTGTAAAATAGACTTTGGAACACATATAAGTGGTAGGATT ATTGACTGTGCTTTTACTGTCACTTTTAATCCCAAATATGATACGTTATTAAAAGCTGTA AAAGATGCTACTAACACTGGAATAAAGTGTGCTGGAATTGATGTTCGTCTGTGTGATGTT GGTGAGGCCATCCAAGAAGTTATGGAGTCCTATGAAGTTGAAATAGATGGGAAGACATAT CAAGTGAAACCAATCCGTAATCTAAATGGACATTCAATTGGGCAATATAGAATACATGCT GGAAAAACAGTGCCGATTGTGAAAGGAGGGGAGGCAACAAGAATGGAGGAAGGAGAAGTA TATGCAATTGAAACCTTTGGTAGTACAGGAAAAGGTGTTGTTCATGATGATATGGAATGT TCACATTACATGAAAAATTTTGATGTTGGACATGTGCCAATAAGGCTTCCAAGAACAAAA CACTTGTTAAATGTCATCAATGAAAACTTTGGAACCCTTGCCTTCTGCCGCAGATGGCTG GATCGCTTGGGAGAAAGTAAATACTTGATGGCTCTGAAGAATCTGTGTGACTTGGGCATT GTAGATCCATATCCACCATTATGTGACATTAAAGGATCATATACAGCGCAATTTGAACAT ACCATCCTGTTGCGTCCAACATGTAAAGAAGTTGTCAGCAGAGGAGATGACTATTAA Clone variation with respect to NM_006838.3 >OriGene 5' read for NM_006838 unedited
NNNTTTGTCAAAATTTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGGGAAG GATCGGGGCCCTCGCCGCTCTGTCTCATTCCCTCGCGCTCTCTCGGGCAACATGGCGGGT GTGGAGGAGGTAGCGGCCTCCGGGAGCCACCTGAATGGCGACCTGGATCCAGACGACAGG GAAGAAGGAGCTGCCTCTACGGCTGAGGAAGCAGCCAAGAAAAAAAGACGAAAGAAGAAG AAGAGCAAAGGGCCTTCTGCAGCAGGGGAACAGGAACCTGATAAAGAATCAGGAGCCTCA GTGGATGAAGTAGCAAGACAGTTGGAAAGATCAGCATTGGAAGATAAAGAAAGAGATGAA GATGATGAAGATGGAGATGGCGATGGAGATGGAGCAACTGGAAAGAAGAAGAAAAAGAAG AAGAAGAAGAGAGGACCAAAAGTTCAAACAGACCCTCCCTCAGTTCCAATATGTGACCTG TATCCTAATGGTGTATTTCCCAAAGGACAAGAATGCGAATACCCACCCACACAAGATGGG CGAACAGCTGCTTGGAGAACTACAAGTGAAGAAAAGAAAGCATTAGATCAGGCAAGTGAA GAGATTTGGAATGATTTTCGAGAAGCTGCAGAAGCACATCGACAAGTTAGAAAATACGTA ATGAGCTGGATCAAGCCTGNGATGACAATGATAGAAATCTGTGAAAAGTTGGAAGACTGT TCACGCAAGTTAATAAAAGAGAATGGATTAAATGCANGCCTGGCATTTCCTACTGGATGN TCTCTCAATAATTGTGCTGCCCATTATACTCCCNAATGCCGTGACACAACAGTATTACAG TATGATGACANTCTGTAAATAGACTTTGGAACCATATNAGTGGNTAGGGATATTGACTGT GNCTTTACT >OriGene 3' read for NM_006838 unedited
NNTTTTAGCTATGNACCCGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTGC TTTTGTGGCTTTAATACCCTTTTGGTTTTCTGAGCAAGCTGAATACATTCCCTGATAAAC ACCACCACTGGACAAAGGATCTAAACATTGAGATTTTTACTAAATCAAGGTTTTGAGTTG GCACAATGTTCCTACTAAGTCAAGTTTCAATTAGCACATCTTTCCAATGTCAGGAGAAAA AAAGACAAGGACTACTATGTCCTACAAAGAATGGTGAAATATTCCTAAAGCTGTATATTT ATGAAGAAAAGGTGATTGTCCCTTTTTATGCATGTGTAGATCTTGTTTTAGCCACTATGC CAGAAAAGTCTCAGTGTAGAGGTCTACATTTCAGATAAATGTCTCTGCATTTGCCTACAT TAAGTTTAGCTATTTATCCTGTCCAGAATTATAACCACAGACATTGAGATGTAGCTCTCA GATCTGAAAATGTCTTTATTTTTTAGAAAATGGATTCCAGGAAGGTTAAAAAGCAACACC AGAGGGTATAGGTGCAGAACTGGATGTAGTCATTCAAAGCATTCAAGTAAGAATATGGCA ATATAAATATCCAAAAAGTATCTCTTAGGTATTCAAAACAAAACGTATAAGTCATTCCTA ACTAATTTGAGCTTTATAGCATTTTCCTAGACAGGAAGGGGAAAAACAGTTAGCATTTAA AAGTCCGGAAAGCTTTTTCGTTGGTTAATTACATTAGACGGTTTGCCTTTGTCCAAATTC CTTCTTTTTTAAACATGGNATANAGTATTACATGGGTCCACTGNTAANAACAGACACATG TGGCANATTAATTCTGGTATCATGTTTTNCCACAAAGCTCAGAAATAAAGTGNTGAGGTG GCTTGGACC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_006838 |
| Insert Size | 2320 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_006838.2, NP_006829.1 |
| RefSeq Size | 1908 bp |
| RefSeq ORF | 1437 bp |
| Locus ID | 10988 |
| UniProt ID | P50579 |
| Domains | Peptidase_M24 |
| Protein Families | Druggable Genome, Protease |
| Gene Summary | The protein encoded by this gene is a member of the methionyl aminopeptidase family. The encoded protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent proteins. Increased expression of this gene is associated with various forms of cancer, and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site. Inhibitors of this gene have also been shown to be effective for the treatment of obesity. A pseudogene of this gene is located on chromosome 2. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015] Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC203809 | METAP2 (Myc-DDK-tagged)-Human methionyl aminopeptidase 2 (METAP2) |
CNY 3,656.00 |
|
| RC203809L1 | Lenti ORF clone of Human methionyl aminopeptidase 2 (METAP2), Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC203809L2 | Lenti ORF clone of Human methionyl aminopeptidase 2 (METAP2), mGFP tagged |
CNY 5,890.00 |
|
| RC203809L3 | Lenti ORF clone of Human methionyl aminopeptidase 2 (METAP2), Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC203809L4 | Lenti ORF clone of Human methionyl aminopeptidase 2 (METAP2), mGFP tagged |
CNY 6,056.00 |
|
| RG203809 | METAP2 (tGFP-tagged) - Human methionyl aminopeptidase 2 (METAP2) |
CNY 5,256.00 |
|
| SC322467 | METAP2 (untagged)-Human methionyl aminopeptidase 2 (METAP2) |
CNY 3,656.00 |
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