CD299 (CLEC4M) (NM_014257) Human Untagged Clone
CAT#: SC115079
CLEC4M (untagged)-Human C-type lectin domain family 4, member M (CLEC4M), transcript variant 1
CNY 3,656.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | CD209L; CD299; DC-SIGN2; DC-SIGNR; DCSIGNR; HP10347; L-SIGN; LSIGN |
Vector | pCMV6-XL5 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene sequence for NM_014257 edited
TGAGGATCAGAGGGTGGAAAATAAAAGCTGTGGTCCCCAGGAGTCCTGAACATCTGGGGA CAGCGGGAAAACATGAGTGACTCCAAGGAACCAAGGGTGCAGCAGCTGGGCCTCCTGGAA GAAGATCCAACAACCAGTGGCATCAGACTTTTTCCAAGAGACTTTCAATTCCAGCAGATA CATGGCCACAAGAGCTCTACAGGGTGTCTTGGCCATGGCGCCCTGGTGCTGCAACTCCTC TCCTTCATGCTCTTGGCTGGGGTCCTGGTGGCCATCCTTGTCCAAGTGTCCAAGGTCCCC AGCTCCCTAAGTCAGGAACAATCCGAGCAAGACGCAATCTACCAGAACCTGACCCAGCTT AAAGCTGCAGTGGGTGAGCTCTCAGAGAAATCCAAGCTGCAGGAGATCTACCAGGAGCTG ACCCAGCTGAAGGCTGCAGTGGGTGAGTTGCCAGAGAAATCCAAGCTGCAGGAGATCTAC CAGGAGCTGACCCGGCTGAAGGCTGCAGTGGGTGAGTTGCCAGAGAAATCCAAGCTGCAG GAGATCTACCAGGAGCTGACCCGGCTGAAGGCTGCAGTGGGTGAGTTGCCAGAGAAATCC AAGCTGCAGGAGATCTACCAGGAGCTGACCCGGCTGAAGGCTGCAGTGGGTGAGTTGCCA GAGAAATCCAAGCTGCAGGAGATCTACCAGGAGCTGACGGAGCTGAAGGCTGCAGTGGGT GAGTTGCCAGAGAAATCCAAGCTGCAGGAGATCTACCAGGAGCTGACCCAGCTGAAGGCT GCAGTGGGTGAGTTGCCAGACCAGTCCAAGCAGCAGCAAATCTATCAAGAACTGACCGAT TTGAAGACTGCATTTGAACGCCTGTGCCGCCACTGTCCCAAGGACTGGACATTCTTCCAA GGAAACTGTTACTTCATGTCTAACTCCCAGCGGAACTGGCACGACTCCGTCACCGCCTGC CAGGAAGTGAGGGCCCAGCTCGTCGTAATCAAAACTGCTGAGGAGCAGAACTTCCTACAG CTGCAGACTTCCAGGAGTAACCGCTTCTCCTGGATGGGACTTTCAGACCTAAATCAGGAA GGCACGTGGCAATGGGTGGACGGCTCACCTCTGTCACCCAGCTTCCAGCGGTACTGGAAC AGTGGAGAACCCAACAATAGCGGGAATGAAGACTGTGCGGAATTTAGTGGCAGTGGCTGG AACGACAATCGATGTGACGTTGACAATTACTGGATCTGCAAAAAGCCCGCAGCCTGCTTC AGAGACGAATAGTTGTTTCCCTGCTAGCCTCAGCCTCCATTGTGGTATAGCAGAACTTCA CCCACTTGTAAGCCAGCGCTTCTTCTCTCCATCCTTGGACCTTCACAAATGCCCTGAGAC GGTTCTCTGTTCGATTTTTCATCCCCTATGAACCTGGGTCTTATTCTGTCCTTCTGATGC CTCCAAGTTTCCCTGGTGTAGAGCTTGTGTTCTTGGCCCATCCTTGGAGCTTTATAAGTG ACCTGAGTGGGATGCATTTAGGGGGCGGGCTTGGTATGTTGTATGAATCCACTCTCTGTT CCTTTTGGAGATTAGACTATTTGGATTCATGTGTAGCTGCCCTGTCCCCTGGGGCTTTAT CTCATCCATGCAAACTACCATCTGCTCAACTTCCAGCTACACCCCGTGCACCCTTTTGAC TGGGGACTTGCTGGTTGAAGGAGCTCATCTTGCAGGCTGGAAGCACCAGGGAATTAATTC CCCCAGTCAACCAATGGCATCCAGAGAGGGCATGGAGGCTCCATACAACCTCTTCCACCC CCACATCTTTCTTTGTCCTATACATGTCTTCCATTTGGCTGTTTCTGAGTTGTAGCCTTT ATAATAAAGTGGTAAATGTTGTAACTGCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAA >OriGene 5' read for NM_014257 unedited
NGGACGTTCACATTTGTAAACGACTCATATAGGGCGGCCGCGATTCCCGGGATTGAGGAT CAGAGGGTGNGAAAATAAAAGCTGTGGTCCCCAGGAGTCCTGACATCTGGGGACAGCGGG AAAACATGAGTGACTCCAAGGAACCAAGGGTGCAGCAGCTGGGCCTCCTGGAAGAAGATC CAACAACCAGTGGCATCAGACTTTTTCCAAGAGACTTTCAATTCCAGCAGATACATGGCC ACAAGAGCTCTACAGGGTGTCTTGGCCATGGCGCCCTGGTGCTGCAACTCCTCTCCTTCA TGCTCTTGGCTGGGGTCCTGGTGGCCATCCTTGTCCAAGTGTCCAAGGTCCCCAGCTCCC TAAGTCAGGAACAATCCGAGCAAGACGCAATCTACCAGAACCTGACCCAGCTTAAAGCTG CAGTGGGTGAGCTCTCAGAGAAATCCAAGCTGCAGGAGATCTACCAGGAGCTGACCCAGC TGAAGGCTGCAGTGGGTGAGTTGCCAGAGAAATCCAAGCTGCAGGAGATCTACCAGGAGC TGACCCGGCTGAAGGCTGCAGTGGGTGAGTTGCCAGAGAAATCCAAGCTGCAGGAGATCT ACCAGGAGCTGACCCGGCTGAAGGCTGCAGTGGGTGAGTTGCCAGAGAAATCCAAGCTGC AGGAGATCTACCAGGAGCTGACCCGGCTGAAGGCTGCAGTGGGTGAGTTGCCAGAGAAAT CCAAGCTGCAGGAGATCTACCAGGAGCTGACGGAGCTGAAGGCTGCAGTGGGTGAGTTGC CAGAGAAATCCAAGCTGCANGAGATCTACCAGGAGCTGACCCAGCTGAANGCTGCAGTGG GTGAGTTGCCAGACCAGTCCAAGCAGCAGCAAATCTATCAAGAACTGACCGATTGNGAGA CTGCA |
Restriction Sites | Please inquire |
ACCN | NM_014257 |
Insert Size | 1930 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_014257.3, NP_055072.3 |
RefSeq Size | 1930 bp |
RefSeq ORF | 1200 bp |
Locus ID | 10332 |
UniProt ID | Q9H2X3 |
Protein Families | Druggable Genome, Transmembrane |
Gene Summary | This gene encodes a C-type lectin that functions in cell adhesion and pathogen recognition. This receptor recognizes a wide range of evolutionarily divergent pathogens with a large impact on public health, including tuberculosis mycobacteria, and viruses including Ebola, hepatitis C, HIV-1, influenza A, West Nile virus and the SARS-CoV acute respiratory syndrome coronavirus. The protein is organized into four distinct domains: a C-terminal carbohydrate recognition domain, a flexible tandem-repeat neck domain of variable length, a transmembrane region and an N-terminal cytoplasmic domain involved in internalization. This gene is closely related in terms of both sequence and function to a neighboring gene, CD209 (Gene ID: 30835), also known as DC-SIGN. The two genes differ in viral recognition and expression patterns, with this gene showing high expression in endothelial cells of the liver, lymph node and placenta. Polymorphisms in the tandem repeat neck domain are associated with resistance to SARS infection. [provided by RefSeq, May 2020] Transcript Variant: This variant (1) encodes the longest isoform (1). |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC207947 | CLEC4M (Myc-DDK-tagged)-Human C-type lectin domain family 4, member M (CLEC4M), transcript variant 1 |
CNY 3,656.00 |
|
RC207947L1 | Lenti ORF clone of Human C-type lectin domain family 4, member M (CLEC4M), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
RC207947L2 | Lenti ORF clone of Human C-type lectin domain family 4, member M (CLEC4M), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
RC207947L3 | Lenti ORF clone of Human C-type lectin domain family 4, member M (CLEC4M), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
RC207947L4 | Lenti ORF clone of Human C-type lectin domain family 4, member M (CLEC4M), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
RG207947 | CLEC4M (tGFP-tagged) - Human C-type lectin domain family 4, member M (CLEC4M), transcript variant 1 |
CNY 5,256.00 |