United States
Germany
Japan
United Kingdom
China
D4S234E (NSG1) (NM_014392) Human Untagged Clone
CAT＃: SC115028
NSG1 (untagged)-Human DNA segment on chromosome 4 (unique) 234 expressed sequence (D4S234E), transcript variant 1
CNY 2,400.00
CNY 2,950.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | D4S234; D4S234E; NEEP21; P21 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC115028 sequence for NM_014392 edited (data generated by NextGen Sequencing)
ATGGTGAAGTTGGGGAACAATTTCGCAGAGAAGGGCACCAAGCAGCCGCTGCTGGAGGAT GGCTTCGACACCATTCCCCTGATGACGCCCCTCGATGTCAATCAGCTGCAGTTCCCGCCC CCGGATAAGGTGGTCGTGAAAACTAAGACCGAGTATGAACCTGACCGCAAGAAAGGGAAA GCACGTCCTCCCCAAATTGCTGAGTTCACCGTCAGCATCACGGAGGGTGTCACCGAGAGG TTTAAGGTCTCCGTGTTGGTCCTCTTCGCCCTGGCCTTCCTCACCTGCGTCGTCTTCCTG GTTGTCTACAAGGTGTACAAGTATGACCGCGCCTGCCCCGATGGGTTCGTCCTCAAGAAC ACCCAGTGCATCCCAGAAGGCTTGGAGAGCTACTACGCGGAGCAAGACTCCAGTGCCCGG GAGAAATTTTACACAGTCATAAACCACTACAACCTGGCCAAGCAGAGCATCACGCGCTCC GTATCGCCCTGGATGTCAGTTCTGTCAGAAGAGAAGCTGTCCGAGCAGGAGACTGAAGCG GCTGAGAAGTCAGCTTAG Clone variation with respect to NM_014392.3 >OriGene 5' read for NM_014392 unedited
AGAAATTGTATACGACTCCTATAGGCGGCCCGCGAATTCGCACGAGGGGCGGCGGCGCGA GGAGGAGGGAGCGGCCGTGGAGCCCAATCGTTCGCTCCCCTTCCCGGGTCCGCGCGCGGC GCCGCCTCCGCCATTGCTGCGAGCAGGAGCAGGAGACGCGGAGCTCGGAGCGCTGAGCTG ACCTGCCGGAGCCGGGCGTGGGCTGCAGCCTCGGAGCTCCCGGAACGATGGTGAAGTTGG GGAACAATTTCGCAGAGAAGGGCACCAAGCAGCCGCTGCTGGAGGATGGCTTCGACACCA TTCCCCTGATGACGCCCCTCGATGTCAATCAGCTGCAGTTCCCGCCCCCGGATAAGGTGG TCGTGAAAACTAAGACCGAGTATGAACCTGACCGCAAGAAAGGGAAAGCACGTCCTCCCC AAATTGCTGAGTTCACCGTCAGCATCACGGAGGGTGTCACCGAGAGGTTTAAGGTCTCCG TGTTGGTCCTCTTCGCCCTGGCCTTCCTCACCTGCGTCGTCTTCCTGGTTGTCTACAAGG TGTACAAGTATGACCGCGCCTGCCCCGATGGGTTCGTCCTCAAGAACACCCAGTGCATCC CAGAAGGCTTGGAGAGCTACTACGCGGAGCAAGACTCCAGTGCCCGGGAGAAATTTTACA CAGTCATAAACCACTACAACCTGGCCAAGCAGAGCATCACGCGCTCCGTATCGCCCTGGA TGTCAGTTCTGTCAGAAGAGAAGCTGTCCGAGCAGGAGACTGAAGCGGCTGAGAAGTCAG CTTAGCGGGATGGGGCAGTTCCCTTACATGTGTCACTTGCNAATACANAGGGACTNTGAG GGNACATTNCATAAATATAATACTGATACTTTANAGGTACTCATTNNACGNNGCANTGCT NCTGTTTGCTAATGGCTGCTTGCAAATAANAACTGCTGCCGACCACCACGGNCATANAAC >OriGene 3' read for NM_014392 unedited
GACCGCGGCCGCAATCTANATCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT TTTTTTTTTTTAACCTCATGTTCTTTATTTGCACAAAGGGAAATGTCAAAAGTTACATGT AAATGAATTCACAGTCAATAAAGTCCACGTTTACCTGGAAATACAGGCTCGGCCTTTGCA CTGGGCGCACACGGGCTTCACTTGGGTCTATTCAAATGCCCAGGGAAACTTTGGCACTGA TTTATTGCTCTTGAGTCATTTTCCACAGCTTAACACCACCCTTTTCAACACACCCCTTTG ATGCACACCGCTGCGCCAAGGTCACGGTCTGTGTCTCCAAACACCCTTGATGAAAAAATA CATTTTCTGTCTTAAAAGCACATTTCAGGAAACAAGAGTGGCGCTGACCACGGTCACCAT GCCTGTTCACAACACATTTCACACTATTTGGCGTTTATTTCTGATCTAAAAAACTGAAAC TTTTGACACGTACCCCAAAAACAACCCTTTCAATAACATAGAAGAAATGTCTGCGAATGT CTTTTCTATTTGTTTTACACACTTAGTTCATCTAACTGGCAGTTTTGTAAACATAAACTT TAATATCAAGATTCAAACTGGAACAATTTTCTTACAAAGATTGTGAGTTGAAATTTGTCA TTTTGTTTGCACGGTGCCACACCCAGTCCCCCACCCCCACCCCACACCTTTCCTGCCTGT TTCCACATCAAGGGATATCAGTTTCATAAATAAAAATTAAAGTAGCTAAGGCTACCAGAA ATACATTTCCACTTTCCCACCAGCTCATTTCTTTAAAACTATGGGGCTTTTGTGCAATTT ATTCTATAAAGTGAACCGAGGGCAGGGGGGTTTTTTCTTANNCATACAGAGCAACAACTC TGGGGGAAGTCTGCT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_014392 |
| Insert Size | 2560 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_014392.2, NP_055207.1 |
| RefSeq Size | 1517 bp |
| RefSeq ORF | 558 bp |
| Locus ID | 27065 |
| UniProt ID | P42857 |
| Protein Families | Druggable Genome, Transmembrane |
| Gene Summary | Plays a role in the recycling mechanism in neurons of multiple receptors, including AMPAR, APP and L1CAM and acts at the level of early endosomes to promote sorting of receptors toward a recycling pathway. Regulates sorting and recycling of GRIA2 through interaction with GRIP1 and then contributes to the regulation of synaptic transmission and plasticity by affecting the recycling and targeting of AMPA receptors to the synapse (By similarity). Is required for faithful sorting of L1CAM to axons by facilitating trafficking from somatodendritic early endosome or the recycling endosome (By similarity). In an other hand, induces apoptosis via the activation of CASP3 in response to DNA damage (PubMed:20599942, PubMed:20878061).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) differs in the 5' UTR compared to variant (3). Variants 1, 2, and 3 all encode the same isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC222554 | NSG1 (Myc-DDK-tagged)-Human DNA segment on chromosome 4 (unique) 234 expressed sequence (D4S234E), transcript variant 1 |
CNY 2,400.00 |
|
| RC222554L1 | Lenti ORF clone of Human DNA segment on chromosome 4 (unique) 234 expressed sequence (D4S234E), transcript variant 1, Myc-DDK-tagged |
CNY 4,800.00 |
|
| RC222554L2 | Lenti ORF clone of Human DNA segment on chromosome 4 (unique) 234 expressed sequence (D4S234E), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RC222554L3 | Lenti ORF clone of Human DNA segment on chromosome 4 (unique) 234 expressed sequence (D4S234E), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC222554L4 | Lenti ORF clone of Human DNA segment on chromosome 4 (unique) 234 expressed sequence (D4S234E), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RG222554 | NSG1 (tGFP-tagged) - Human DNA segment on chromosome 4 (unique) 234 expressed sequence (D4S234E), transcript variant 1 |
CNY 4,000.00 |
其它D4S234E产品
