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TOMM20 (NM_014765) Human Untagged Clone
CAT＃: SC114860
TOMM20 (untagged)-Human translocase of outer mitochondrial membrane 20 homolog (yeast) (TOMM20), nuclear gene encoding mitochondrial protein
CNY 1,200.00
CNY 2,950.00
| Cited in 2 publications. |
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热销推荐Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | MAS20; MOM19; TOM20 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC114860 sequence for NM_014765 edited (data generated by NextGen Sequencing)
ATGGTGGGTCGGAACAGCGCCATCGCCGCCGGTGTATGCGGGGCCCTTTTCATTGGGTAC TGCATCTACTTCGACCGCAAAAGACGAAGTGACCCCAACTTCAAGAACAGGCTTCGAGAA CGAAGAAAGAAACAGAAGCTTGCCAAGGAGAGAGCTGGGCTTTCCAAGTTACCTGACCTT AAAGATGCTGAAGCTGTTCAGAAGTTCTTCCTTGAAGAAATACAGCTTGGTGAAGAGTTA CTAGCTCAAGGTGAATATGAGAAGGGCGTAGACCATCTGACAAATGCAATTGCTGTGTGT GGACAGCCACAGCAGTTACTGCAGGTCTTACAGCAAACTCTTCCACCACCAGTGTTCCAG ATGCTTCTGACTAAGCTCCCAACAATTAGTCAGAGAATTGTAAGTGCTCAGAGCTTGGCT GAAGATGATGTGGAATGA Clone variation with respect to NM_014765.2 >OriGene 5' read for NM_014765 unedited
CTTGGATTTTGTAACACGACTTACTATAGGGCGGCCGCGCATTCGGCACGAGGGACGACC TCGAGGCCCTTAGTTGACTGGGACCGGAAGTGGCGTGTGCTCGGCCTTTCTGTGTTCCTG GCCCGCGGCCGTCGGGTGTGAGCTGCGCCGACCGCTCTGAGGGTTCGTGGCCCACCGCTC CTTCGCGGTCCCTGCCGCCACCGTCCACGCTCATCGTTGTAGAGAAGATGGTGGGTCGGA ACAGCGCCATCGCCGCCGGTGTATGCGGGGCCCTTTTCATTGGGTACTGCATCTACTTCG ACCGCAAAAGACGAAGTGACCCCAACTTCAAGAACAGGCTTCGAGAACGAAGAAAGAAAC AGAAGCTTGCCAAGGAGAGAGCTGGGCTTTCCAAGTTACCTGACCTTAAAGATGCTGAAG CTGTTCAGAAGTTCTTCCTTGAAGAAATACAGCTTGGTGAAGAGTTACTAGCTCAAGGTG AATATGAGAAGGGCGTAGACCATCTGACAAATGCAATTGCTGTGTGTGGACAGCCACAGC AGTTACTGCAGGTCTTACAGCAAACTCTTCCACCACCAGTGTTCCAGATGCTTCTGACTA AGCTCCCAACAATTAGTCAGAGAATTGTAAGTGCTCAGAGCTTGGCTGAAGATGATGTGG AATGAGAAACAAATGTCAACATAATAAAATCTCAGTTAAAAATATTTTAAAAATTCTTGG TAGTTGAGCAGCTCTGGGGGAATATGGCANATATGCTTGTTATGAACCTACACTGAATCT ACCANAGTTAATGTTTACTTTGAGTAGATCCATTTGTCTATTTTATTTATTTTTCCCAGT GAAAAGTGTATTTTGATAGAGGACTTTTCATTCTATAATACACTATGAGTACTAAAATAT CATGGATTTGTTNATTCCCTGAACATAGTACTAGTTAAACTGACATAT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_014765 |
| Insert Size | 3000 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_014765.1, NP_055580.1 |
| RefSeq Size | 3259 bp |
| RefSeq ORF | 438 bp |
| Locus ID | 9804 |
| UniProt ID | Q15388 |
| Domains | MAS20 |
| Protein Families | Druggable Genome, Transmembrane |
| Gene Summary | Central component of the receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with TOM22 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the TOM40 translocation pore (By similarity). Required for the translocation across the mitochondrial outer membrane of cytochrome P450 monooxygenases.[UniProtKB/Swiss-Prot Function] |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Defective mitochondrial protein import contributes to complex I-induced mitochondrial dysfunction and neurodegeneration in Parkinson's disease
,Franco-Iborra, S;Cuadros, T;Parent, A;Romero-Gimenez, J;Vila, M;Perier, C;,
Cell Death Dis
,PubMed ID 30405116
[TOMM20]
|
|
Removal or masking of phosphatidylinositol(4,5)bisphosphate from the outer mitochondrial membrane causes mitochondrial fragmentation
,null,
Cellular Signalling
,PubMed ID 21044681
[TOMM20]
|
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Other Versions
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|---|---|---|---|
| RC210746 | TOMM20 (Myc-DDK-tagged)-Human translocase of outer mitochondrial membrane 20 homolog (yeast) (TOMM20), nuclear gene encoding mitochondrial protein |
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| RC210746L1 | Lenti ORF clone of Human translocase of outer mitochondrial membrane 20 homolog (yeast) (TOMM20), nuclear gene encoding mitochondrial protein, Myc-DDK-tagged |
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| RC210746L2 | Lenti ORF clone of Human translocase of outer mitochondrial membrane 20 homolog (yeast) (TOMM20), nuclear gene encoding mitochondrial protein, mGFP tagged |
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| RC210746L3 | Lenti ORF clone of Human translocase of outer mitochondrial membrane 20 homolog (yeast) (TOMM20), nuclear gene encoding mitochondrial protein, Myc-DDK-tagged |
CNY 5,890.00 |
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| RC210746L4 | Lenti ORF clone of Human translocase of outer mitochondrial membrane 20 homolog (yeast) (TOMM20), nuclear gene encoding mitochondrial protein, mGFP tagged |
CNY 3,600.00 |
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| RG210746 | TOMM20 (tGFP-tagged) - Human translocase of outer mitochondrial membrane 20 homolog (yeast) (TOMM20), nuclear gene encoding mitochondrial protein |
CNY 2,800.00 |
