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PITRM1 (NM_014889) Human Untagged Clone
CAT＃: SC114737
PITRM1 (untagged)-Human pitrilysin metallopeptidase 1 (PITRM1), nuclear gene encoding mitochondrial protein, transcript variant 2
CNY 10,840.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | MP1; PreP |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC114737 sequence for NM_014889 edited (data generated by NextGen Sequencing)
ATGTGGCGCTGCGGCGGGCGGCAGGGCCTGTGTGTGCTGAGGCGGCTGAGCGGCGGACAT GCACACCACAGAGCGTGGCGATGGAACAGTAACCGGGCTTGTGAGAGGGCTCTGCAGTAT AAACTAGGAGACAAGATCCATGGATTCACCGTAAACCAGGTGACATCTGTTCCCGAGCTG TTCCTGACTGCAGTGAAGCTCACCCATGATGACACAGGAGCCAGGTATTTACACCTGGCC AGAGAAGACACGAATAATCTGTTCAGCGTGCAGTTCCGTACTACTCCCATGGACAGTACT GGTGTTCCTCACATTCTTGAGCATACCGTCCTTTGTGGGTCTCAGAAATATCCGTGCAGA GACCCTTTCTTCAAAATGTTGAACCGGTCCCTCTCCACGTTCATGAACGCCTTCACAGCT AGTGATTATACTCTGTATCCATTTTCCACACAAAATCCCAAGGACTTTCAGAATCTCCTC TCGGTGTATTTGGATGCCACCTTTTTCCCATGTTTACGCGAGCTGGATTTCTGGCAGGAA GGATGGCGGCTGGAACATGAGAATCCGAGCGACCCCCAGACGCCCTTGGTCTTTAAAGGA GTCGTCTTTAATGAGATGAAGGGAGCGTTTACAGACAATGAGAGGATATTCTCCCAGCAC CTTCAGAACAGACTTCTTCCTGACCACACGTACTCAGTGGTCTCCGGGGGTGACCCACTG TGCATCCCGGAGCTTACATGGGAGCAGCTTAAGCAGTTTCATGCCACTCACTATCACCCA AGCAATGCTAGGTTCTTCACGTACGGTAATTTTCCATTAGAACAGCATCTGAAACAAATT CACGAGGAAGCACTGAGCAAATTCCAGAAAATTGAACCAAGCACCGTGGTGCCAGCTCAG ACACCCTGGGACAAGCCTAGGGAATTCCAGATAACATGTGGCCCGGATTCATTTGCTACA GATCCCTCTAAACAAACAACCATCAGCGTTAGCTTCCTCTTACCGGACATCACCGACACA TTTGAAGCCTTCACATTAAGTCTTCTGTCTTCACTCTTGACTTCTGGGCCCAATTCTCCC TTTTACAAAGCCTTGATTGAATCTGGCCTTGGCACAGACTTTTCTCCTGATGTTGGATAT AATGGCTACACGAGGGAGGCCTACTTTAGTGTCGGCCTCCAAGGGATTGCGGAGAAAGAC ATTGAGACCGTCAGAAGCCTCATAGACAGAACGATTGATGAAGTAGTTGAGAAAGGATTT GAAGATGATCGAATTGAGGCTTTACTTCATAAAATTGAAATACAGATGAAACATCAGTCT ACCAGCTTTGGGCTGATGCTGACATCATACATAGCTTCTTGCTGGAACCATGATGGGGAC CCTGTGGAGCTCTTGAAGTTGGGAAATCAGTTAGCTAAATTCAGACAGTGCCTGCAGGAA AATCCAAAATTTTTGCAAGAAAAAGTAAAACAGTATTTTAAGAATAACCAGCATAAGCTG ACTTTATCGATGAGGCCAGATGACAAGTATCACGAGAAGCAGGCACAGGTGGAAGCCACG AAGCTCAAGCAGAAGGTCGAGGCTCTGTCCCCCGGAGACAGGCAGCAGATCTACGAGAAA GGTCTAGAATTACGGAGTCAACAAAGCAAACCTCAAGATGCCTCTTGTCTGCCAGCGTTG AAAGTTTCCGATATTGAACCCACCATACCTGTCACAGAGTTGGACGTGGTCCTGACAGCT GGAGATATCCCTGTTCAGTACTGCGCCCAGCCCACCAATGGCATGGTGTATTTCCGGGCC TTCTCCAGCCTGAACACACTCCCCGAGGAGCTGAGGCCCTATGTGCCCCTCTTCTGCAGC GTCCTCACCAAGCTGGGCTGCGGCCTTCTTGACTACCGGGAGCAGGCTCAGCAGATAGAA TTGAAGACCGGAGGGATGAGTGCTTCTCCCCACGTGCTCCCCGACGACTCACACATGGAC ACCTACGAGCAGGGTGTGCTTTTCTCCTCTCTCTGCCTGGATCGAAACCTGCCAGACATG ATGCAGCTATGGAGTGAAATATTTAACAACCCGTGCTTTGAAGAAGAGGAGCACTTCAAG GTGCTGGTGAAGATGACCGCCCAGGAGCTCGCCAATGGAATTCCTGACTCTGGGCACCTG TACGCATCCATCAGGGCAGGCCGGACCCTCACGCCCGCAGGGGACCTGCAGGAGACCTTC AGCGGGATGGATCAGGTGCGGCTGATGAAGAGGATTGCAGAAATGACAGATATCAAACCC ATCCTGAGGAAGCTCCCGCGTATCAAGAAACACTTGTTAAATGGTGATAATATGAGGTGT TCAGTGAATGCGACTCCTCAGCAGATGCCTCAGACAGAAAAAGCGGTCGAAGACTTCCTT AGAAGCATCGGTCGGAGTAAAAAGGAACGGAGGCCTGTGCGCCCACACACGGTCGAGAAA CCTGTGCCCAGCAGCTCTGGTGGAGATGCCCACGTTCCCCATGGCTCCCAGGTCATTAGG AAGCTGGTCATGGAACCCACCTTCAAGCCCTGGCAGATGAAGACTCACTTCCTGATGCCC TTCCCGGTGAATTACGTGGGTGAATGCATCCGAACTGTCCCCTACACGGACCCAGATCAT GCCAGTCTTAAAATCCTTGCACGTTTGATGACTGCCAAATTCTTGCATACAGAAATTCGA GAAAAAGGCGGTGCTTATGGTGGAGGCGCAAAACTCAGCCACAATGGGATTTTCACCCTT TACTCTTACAGGGACCCAAATACAATAGAGACGCTCCAGTCTTTTGGGAAGGCTGTCGAC TGGGCTAAGTCTGGAAAATTCACACAGCAAGACATCGACGAAGCCAAACTTTCTGTCTTC TCAACCGTAGATGCTCCTGTCGCTCCTTCAGACAAAGGAATGGACCACTTCTTGTACGGC CTCTCGGATGAGATGAAGCAGGCCCACAGAGAGCAGCTCTTTGCTGTCAGCCACGACAAG CTCCTGGCCGTGAGCGATAGATACCTCGGCACTGGGAAGAGCACACACGGCCTGGCCATC CTCGGACCCGAGAACCCGAAAATTGCCAAGGACCCATCCTGGATCATCCAATGA Clone variation with respect to NM_014889.3 >OriGene 5' read for NM_014889 unedited
TATACGACAACTATAGGGCGGCCGCGATTCGGCACGAGGGCGCAATGTGGCGCTGCGGCG GGCGGCAGGGCCTGTGTGTGCTGAGGCGGCTGAGCGGCGGACATGCACACCACAGAGCGT GGCGATGGAACAGTAACCGGGCTTGTGAGAGGGCTCTGCAGTATAAACTAGGAGACAAGA TCCATGGATTCACCGTAAACCAGGTGACATCTGTTCCCGAGCTGTTCCTGACTGCAGTGA AGCTCACCCATGATGACACAGGAGCCAGGTATTTACACCTGGCCAGAGAAGACACGAATA ATCTGTTCAGCGTGCAGTTCCGTACTACTCCCATGGACAGTACTGGTGTTCCTCACATTC TTGAGCATACCGTCCTTTGTGGGTCTCAGAAATATCCGTGCAGAGACCCTTTCTTCAAAA TGTTGAACCGGTCCCTCTCCACGTTCATGAACGCCTTCACAGCTAGTGATTATACTCTGT ATCCATTTTCCACACAAAATCCCAAGGACTTTCAGAATCTCCTCTCGGTGTATTTGGATG CCACCTTTTTCCCATGTTTACGCGAGCTGGATTTCTGGCAGGAAGGATGGCGGCTGGAAC ATGAGAATCCGAGCGACCCCCAGACGCCCTTGGTCTTTAAAGGNAGTCGTCTTTAATGAG ATGAANGGGAGNCGTTACAGACAATGAGAGGATATTCTCCCAGCACCTTCAGAACAGACT TCTTNCTGACCACACGTACTNCAGTGGTCTNCGGGGGGTGACCCACTGTGCATCCCGGAG CTACATGGGAGCAGCTTTAGCAGTTTATGCCACTCACTATACCCAGCATGGCTAGGTTTT TACGTCGGGAATTTTTCATTAAACAGCTTGAACAAATCGAGGAGCCTGGGCAATCAAAAT GACAGNCCCCGGGGGCACTTNAAACCCTGGCAGCTAGGATCAAAAAATGGCCGGATTTTT TTAAAACCTTAACAACATAA >OriGene 3' read for NM_014889 unedited
ACTCTCTGGACCCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTTT AAGTCAGAGTTGCCCTTTATTTTTAGATTCTTAAATATTCTAGAATGAGGTAAAACGAGC CTGCCAGTACAAAGTGAAAATTCTACATGGTGCATCTTTGGCGCTTCATGCATGATTATT TCAATGAACCTCTTCCTGGTCACTCTTAAGATAGATCTGAGTTTTTGACTCGCCAGTCAA GGGCTTTGGCGACACTCAATGACATAATATTCTTGGAAAAAGCAGTAGCATTTCTGACTT TTCATATTCAGCTCGGAGGTGTATTGTCTCGGGCTCCTGTGCAGTCGAGCGCCACGGCTG CTCATTGGATGATCCAGGATGGGTCCTTGGCAATTTTCGGGTTCTCGGGTCCGAGGATGG CCAGGCCGTGTGTGCTCTTCCCAGTGCCGAGGTATCTATCGCTCACGGCCAGGAGCTTGT CGTGGCTGACAGCAAAGAGCTGCTCTCTGTGGGCCTGCTTCATCTCATCCGAGAGGCCGT ACAAGAAGTGGTCCATTCCTTTGTCTGAAGGAGCGACAGGAGCATCTACGGTTGAGAAGA CAGAAAGTTTGGCTTCGTCGATGTCTTGCTGTGTGAATTTTCCAGACTTAGCCCAGTCGA CAGCCTTCCCAAAAGACTGGAGCGTCTCTATTGTATTTTGGTCCCTGTAGAGTAAAGGGG TGAAATCCCATTGTGGCTGAGTTTTGCGCCTCCCCATAGCCACCGNCTTTTTCTCGAATT TCTGTATGCAAGAATTTGGCAGTCATCAAACGTGCAAGGATTTAAGACTGCCATGATCTG GGTCCGTGTAGGGGACAGTTCGGATGCATTCACCCACGTATTTACCGGGAAGGGCATCAN GAAGTGAGTCTCATCTGCCAGGCCTTGAAGGTGGGTCCTGAG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_014889 |
| Insert Size | 5270 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_014889.2, NP_055704.2 |
| RefSeq Size | 3465 bp |
| RefSeq ORF | 3114 bp |
| Locus ID | 10531 |
| UniProt ID | Q5JRX3 |
| Domains | Peptidase_M16_C |
| Protein Families | Druggable Genome, Protease |
| Gene Summary | The protein encoded by this gene is an ATP-dependent metalloprotease that degrades post-cleavage mitochondrial transit peptides. The encoded protein binds zinc and can also degrade amyloid beta A4 protein, suggesting a possible role in Alzheimer's disease. [provided by RefSeq, Dec 2016] Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. This results in a shorter protein (isoform 2), compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC210596 | PITRM1 (Myc-DDK-tagged)-Human pitrilysin metallopeptidase 1 (PITRM1), nuclear gene encoding mitochondrial protein, transcript variant 2 |
CNY 10,832.00 |
|
| RC210596L1 | Lenti ORF clone of Human pitrilysin metallopeptidase 1 (PITRM1), nuclear gene encoding mitochondrial protein, transcript variant 2, Myc-DDK-tagged |
CNY 13,232.00 |
|
| RC210596L2 | Lenti ORF clone of Human pitrilysin metallopeptidase 1 (PITRM1), nuclear gene encoding mitochondrial protein, transcript variant 2, mGFP tagged |
CNY 12,260.00 |
|
| RC210596L3 | Lenti ORF clone of Human pitrilysin metallopeptidase 1 (PITRM1), nuclear gene encoding mitochondrial protein, transcript variant 2, Myc-DDK-tagged |
CNY 12,260.00 |
|
| RC210596L4 | Lenti ORF clone of Human pitrilysin metallopeptidase 1 (PITRM1), nuclear gene encoding mitochondrial protein, transcript variant 2, mGFP tagged |
CNY 12,260.00 |
|
| RG210596 | PITRM1 (tGFP-tagged) - Human pitrilysin metallopeptidase 1 (PITRM1), nuclear gene encoding mitochondrial protein, transcript variant 2 |
CNY 11,400.00 |
